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Items: 1 to 50 of 441

1.

Immunophenotyping of cerebrospinal fluid cells in ischaemic stroke.

Schulte-Mecklenbeck A, Kleffner I, Beuker C, Wirth T, Hartwig M, Schmidt-Pogoda A, Klotz L, Hansen W, Wiendl H, Meuth SG, Gross CC, Minnerup J.

Eur J Neurol. 2019 Jan 19. doi: 10.1111/ene.13909. [Epub ahead of print]

PMID:
30659722
2.

Immune Cell Activation in the Cerebrospinal Fluid of Patients With Parkinson's Disease.

Schröder JB, Pawlowski M, Meyer Zu Hörste G, Gross CC, Wiendl H, Meuth SG, Ruck T, Warnecke T.

Front Neurol. 2018 Dec 18;9:1081. doi: 10.3389/fneur.2018.01081. eCollection 2018.

3.

Dietary salt promotes ischemic brain injury and is associated with parenchymal migrasome formation.

Schmidt-Pogoda A, Strecker JK, Liebmann M, Massoth C, Beuker C, Hansen U, König S, Albrecht S, Bock S, Breuer J, Sommer C, Schwab N, Wiendl H, Klotz L, Minnerup J.

PLoS One. 2018 Dec 27;13(12):e0209871. doi: 10.1371/journal.pone.0209871. eCollection 2018.

4.

Plasma kallikrein modulates immune cell trafficking during neuroinflammation via PAR2 and bradykinin release.

Göbel K, Asaridou CM, Merker M, Eichler S, Herrmann AM, Geuß E, Ruck T, Schüngel L, Groeneweg L, Narayanan V, Schneider-Hohendorf T, Gross CC, Wiendl H, Kehrel BE, Kleinschnitz C, Meuth SG.

Proc Natl Acad Sci U S A. 2019 Jan 2;116(1):271-276. doi: 10.1073/pnas.1810020116. Epub 2018 Dec 17.

PMID:
30559188
5.

Can we predict cognitive decline after initial diagnosis of multiple sclerosis? Results from the German National early MS cohort (KKNMS).

Johnen A, Bürkner PC, Landmeyer NC, Ambrosius B, Calabrese P, Motte J, Hessler N, Antony G, König IR, Klotz L, Hoshi MM, Aly L, Groppa S, Luessi F, Paul F, Tackenberg B, Bergh FT, Kümpfel T, Tumani H, Stangel M, Weber F, Bayas A, Wildemann B, Heesen C, Zettl UK, Zipp F, Hemmer B, Meuth SG, Gold R, Wiendl H, Salmen A; German Competence Network Multiple Sclerosis (KKNMS).

J Neurol. 2019 Feb;266(2):386-397. doi: 10.1007/s00415-018-9142-y. Epub 2018 Dec 4.

PMID:
30515631
6.

Targeting Voltage-Dependent Calcium Channels with Pregabalin Exerts a Direct Neuroprotective Effect in an Animal Model of Multiple Sclerosis.

Hundehege P, Fernandez-Orth J, Römer P, Ruck T, Müntefering T, Eichler S, Cerina M, Epping L, Albrecht S, Menke AF, Birkner K, Göbel K, Budde T, Zipp F, Wiendl H, Gorji A, Bittner S, Meuth SG.

Neurosignals. 2018 Nov 27;26(1):77-93. doi: 10.1159/000495425. [Epub ahead of print]

7.

Efficacy and safety of alemtuzumab versus fingolimod in RRMS after natalizumab cessation.

Pfeuffer S, Schmidt R, Straeten FA, Pul R, Kleinschnitz C, Wieshuber M, Lee DH, Linker RA, Doerck S, Straeten V, Windhagen S, Pawlitzki M, Aufenberg C, Lang M, Eienbroeker C, Tackenberg B, Limmroth V, Wildemann B, Haas J, Klotz L, Wiendl H, Ruck T, Meuth SG.

J Neurol. 2019 Jan;266(1):165-173. doi: 10.1007/s00415-018-9117-z. Epub 2018 Nov 16.

PMID:
30446966
8.

Vitiligo after alemtuzumab treatment: Secondary autoimmunity is not all about B cells.

Ruck T, Pfeuffer S, Schulte-Mecklenbeck A, Gross CC, Lindner M, Metze D, Ehrchen J, Sondermann W, Pul R, Kleinschnitz C, Wiendl H, Meuth SG, Klotz L.

Neurology. 2018 Dec 11;91(24):e2233-e2237. doi: 10.1212/WNL.0000000000006648. Epub 2018 Nov 7.

9.

Intubation, tracheostomy, and decannulation in patients with Guillain-Barré-syndrome-does dysphagia matter?

Schröder JB, Marian T, Muhle P, Claus I, Thomas C, Ruck T, Wiendl H, Warnecke T, Suntrup-Krueger S, Meuth S, Dziewas R.

Muscle Nerve. 2019 Feb;59(2):194-200. doi: 10.1002/mus.26377. Epub 2018 Dec 18.

PMID:
30390307
10.

Apraxia screening predicts Alzheimer pathology in frontotemporal dementia.

Pawlowski M, Joksch V, Wiendl H, Meuth SG, Duning T, Johnen A.

J Neurol Neurosurg Psychiatry. 2018 Oct 10. pii: jnnp-2018-318470. doi: 10.1136/jnnp-2018-318470. [Epub ahead of print]

PMID:
30305323
11.

Primary B Cell Lymphoma of the CNS Mimicking Anti-LGI1 Limbic Encephalitis.

Thomas C, Lehrich C, Gross CC, Wiendl H, Meuth SG, Melzer N.

Front Neurol. 2018 Aug 10;9:658. doi: 10.3389/fneur.2018.00658. eCollection 2018.

12.

Blockade of MCAM/CD146 impedes CNS infiltration of T cells over the choroid plexus.

Breuer J, Korpos E, Hannocks MJ, Schneider-Hohendorf T, Song J, Zondler L, Herich S, Flanagan K, Korn T, Zarbock A, Kuhlmann T, Sorokin L, Wiendl H, Schwab N.

J Neuroinflammation. 2018 Aug 22;15(1):236. doi: 10.1186/s12974-018-1276-4.

13.

The Coagulation Factors Fibrinogen, Thrombin, and Factor XII in Inflammatory Disorders-A Systematic Review.

Göbel K, Eichler S, Wiendl H, Chavakis T, Kleinschnitz C, Meuth SG.

Front Immunol. 2018 Jul 26;9:1731. doi: 10.3389/fimmu.2018.01731. eCollection 2018.

14.

Discriminative power of intra-retinal layers in early multiple sclerosis using 3D OCT imaging.

Seitz CB, Droby A, Zaubitzer L, Krämer J, Paradis M, Klotz L, Wiendl H, Groppa S, Meuth SG, Zipp F, Fleischer V.

J Neurol. 2018 Oct;265(10):2284-2294. doi: 10.1007/s00415-018-8988-3. Epub 2018 Aug 2.

PMID:
30073502
15.

Nur77 serves as a molecular brake of the metabolic switch during T cell activation to restrict autoimmunity.

Liebmann M, Hucke S, Koch K, Eschborn M, Ghelman J, Chasan AI, Glander S, Schädlich M, Kuhlencord M, Daber NM, Eveslage M, Beyer M, Dietrich M, Albrecht P, Stoll M, Busch KB, Wiendl H, Roth J, Kuhlmann T, Klotz L.

Proc Natl Acad Sci U S A. 2018 Aug 21;115(34):E8017-E8026. doi: 10.1073/pnas.1721049115. Epub 2018 Aug 2.

PMID:
30072431
16.

Immune Cell Profiling During Switching from Natalizumab to Fingolimod Reveals Differential Effects on Systemic Immune-Regulatory Networks and on Trafficking of Non-T Cell Populations into the Cerebrospinal Fluid-Results from the ToFingo Successor Study.

Lohmann L, Janoschka C, Schulte-Mecklenbeck A, Klinsing S, Kirstein L, Hanning U, Wirth T, Schneider-Hohendorf T, Schwab N, Gross CC, Eveslage M, Meuth SG, Wiendl H, Klotz L.

Front Immunol. 2018 Jul 9;9:1560. doi: 10.3389/fimmu.2018.01560. eCollection 2018.

17.

Impairment of frequency-specific responses associated with altered electrical activity patterns in auditory thalamus following focal and general demyelination.

Narayanan V, Cerina M, Göbel K, Meuth P, Herrmann AM, Fernandez-Orth J, Stangel M, Gudi V, Skripuletz T, Daldrup T, Lesting J, Schiffler P, Wiendl H, Seidenbecher T, Meuth SG, Budde T, Pape HC.

Exp Neurol. 2018 Nov;309:54-66. doi: 10.1016/j.expneurol.2018.07.010. Epub 2018 Jul 23.

PMID:
30048715
18.

Primary angiitis of the central nervous system: diagnosis and treatment.

Beuker C, Schmidt A, Strunk D, Sporns PB, Wiendl H, Meuth SG, Minnerup J.

Ther Adv Neurol Disord. 2018 Jul 9;11:1756286418785071. doi: 10.1177/1756286418785071. eCollection 2018. Review.

19.

Apraxia profiles-A single cognitive marker to discriminate all variants of frontotemporal lobar degeneration and Alzheimer's disease.

Johnen A, Reul S, Wiendl H, Meuth SG, Duning T.

Alzheimers Dement (Amst). 2018 May 16;10:363-371. doi: 10.1016/j.dadm.2018.04.002. eCollection 2018.

20.

Onconeural antigen spreading in paraneoplastic neurological disease due to small cell lung cancer.

Dik A, Strippel C, Mönig C, Golombeck KS, Schulte-Mecklenbeck A, Wiendl H, Meuth SG, Johnen A, Gross CC, Melzer N.

Oxf Med Case Reports. 2018 Jul 9;2018(7):omy034. doi: 10.1093/omcr/omy034. eCollection 2018 Jul.

21.

Immune cell profiling in the cerebrospinal fluid of patients with primary angiitis of the central nervous system reflects the heterogeneity of the disease.

Strunk D, Schulte-Mecklenbeck A, Golombeck KS, Meyer Zu Hörste G, Melzer N, Beuker C, Schmidt A, Wiendl H, Meuth SG, Gross CC, Minnerup J.

J Neuroimmunol. 2018 Aug 15;321:109-116. doi: 10.1016/j.jneuroim.2018.06.004. Epub 2018 Jun 7.

PMID:
29957380
22.

Amygdala enlargement and emotional responses in (autoimmune) temporal lobe epilepsy.

Holtmann O, Schlossmacher I, Moenig C, Johnen A, Rutter LM, Tenberge JG, Schiffler P, Everding J, Golombeck KS, Strippel C, Dik A, Schwindt W, Wiendl H, Meuth SG, Bruchmann M, Melzer N, Straube T.

Sci Rep. 2018 Jun 22;8(1):9561. doi: 10.1038/s41598-018-27914-z.

23.

Cerebrospinal Fluid Concentrations of Neuronal Proteins Are Reduced in Primary Angiitis of the Central Nervous System.

Ruland T, Wolbert J, Gottschalk MG, König S, Schulte-Mecklenbeck A, Minnerup J, Meuth SG, Groß CC, Wiendl H, Meyer Zu Hörste G.

Front Neurol. 2018 Jun 5;9:407. doi: 10.3389/fneur.2018.00407. eCollection 2018.

24.

DNA methylation as a mediator of HLA-DRB1*15:01 and a protective variant in multiple sclerosis.

Kular L, Liu Y, Ruhrmann S, Zheleznyakova G, Marabita F, Gomez-Cabrero D, James T, Ewing E, Lindén M, Górnikiewicz B, Aeinehband S, Stridh P, Link J, Andlauer TFM, Gasperi C, Wiendl H, Zipp F, Gold R, Tackenberg B, Weber F, Hemmer B, Strauch K, Heilmann-Heimbach S, Rawal R, Schminke U, Schmidt CO, Kacprowski T, Franke A, Laudes M, Dilthey AT, Celius EG, Søndergaard HB, Tegnér J, Harbo HF, Oturai AB, Olafsson S, Eggertsson HP, Halldorsson BV, Hjaltason H, Olafsson E, Jonsdottir I, Stefansson K, Olsson T, Piehl F, Ekström TJ, Kockum I, Feinberg AP, Jagodic M.

Nat Commun. 2018 Jun 19;9(1):2397. doi: 10.1038/s41467-018-04732-5.

25.

A Novel PKD1 Mutation Associated With Autosomal Dominant Kidney Disease and Cerebral Cavernous Malformation.

Thomas C, Zühlsdorf A, Hörtnagel K, Mulahasanovic L, Grauer OM, Kümpers P, Wiendl H, Meuth SG.

Front Neurol. 2018 May 25;9:383. doi: 10.3389/fneur.2018.00383. eCollection 2018.

26.

Natalizumab treatment shows low cumulative probabilities of confirmed disability worsening to EDSS milestones in the long-term setting.

Trojano M, Butzkueven H, Kappos L, Wiendl H, Spelman T, Pellegrini F, Chen Y, Dong Q, Koendgen H, Belachew S; Tysabri® Observational Program (TOP) Investigators.

Mult Scler Relat Disord. 2018 Aug;24:11-19. doi: 10.1016/j.msard.2018.04.020. Epub 2018 May 2.

27.

Immunophenotyping of cerebrospinal fluid cells by Chipcytometry.

Hümmert MW, Alvermann S, Gingele S, Gross CC, Wiendl H, Mirenska A, Hennig C, Stangel M.

J Neuroinflammation. 2018 May 25;15(1):160. doi: 10.1186/s12974-018-1176-7.

28.

Does the environment influence multiple sclerosis pathogenesis via UVB light and/or induction of vitamin D?

Breuer J, Loser K, Mykicki N, Wiendl H, Schwab N.

J Neuroimmunol. 2018 May 18. pii: S0165-5728(17)30478-2. doi: 10.1016/j.jneuroim.2018.05.006. [Epub ahead of print] Review.

PMID:
29793727
29.

Protective potential of dimethyl fumarate in a mouse model of thalamocortical demyelination.

Cerina M, Narayanan V, Delank A, Meuth P, Graebenitz S, Göbel K, Herrmann AM, Albrecht S, Daldrup T, Seidenbecher T, Gorji A, Kuhlmann T, Wiendl H, Kleinschnitz C, Speckmann EJ, Pape HC, Meuth SG, Budde T.

Brain Struct Funct. 2018 May 9. doi: 10.1007/s00429-018-1680-7. [Epub ahead of print]

30.

Time-resolved transcriptome and proteome landscape of human regulatory T cell (Treg) differentiation reveals novel regulators of FOXP3.

Schmidt A, Marabita F, Kiani NA, Gross CC, Johansson HJ, Éliás S, Rautio S, Eriksson M, Fernandes SJ, Silberberg G, Ullah U, Bhatia U, Lähdesmäki H, Lehtiö J, Gomez-Cabrero D, Wiendl H, Lahesmaa R, Tegnér J.

BMC Biol. 2018 May 7;16(1):47. doi: 10.1186/s12915-018-0518-3.

31.

Defining mechanisms of neural plasticity after brainstem ischemia in rats.

Minnerup J, Strecker JK, Wachsmuth L, Hoppen M, Schmidt A, Hermann DM, Wiendl H, Meuth S, Faber C, Diederich K, Schäbitz WR.

Ann Neurol. 2018 May;83(5):1003-1015. doi: 10.1002/ana.25238. Epub 2018 May 11.

PMID:
29665155
32.

Mechanisms underlying lesion development and lesion distribution in CNS autoimmunity.

Lindner M, Klotz L, Wiendl H.

J Neurochem. 2018 Jul;146(2):122-132. doi: 10.1111/jnc.14339. Epub 2018 May 16. Review.

PMID:
29574788
33.

Association of smoking but not HLA-DRB1*15:01, APOE or body mass index with brain atrophy in early multiple sclerosis.

Graetz C, Gröger A, Luessi F, Salmen A, Zöller D, Schultz J, Siller N, Fleischer V, Bellenberg B, Berthele A, Biberacher V, Havla J, Hecker M, Hohlfeld R, Infante-Duarte C, Kirschke JS, Kümpfel T, Linker R, Paul F, Pfeuffer S, Sämann P, Toenges G, Weber F, Zettl UK, Jahn-Eimermacher A, Antony G, Groppa S, Wiendl H, Hemmer B, Mühlau M, Lukas C, Gold R, Lill CM, Zipp F.

Mult Scler. 2018 Mar 1:1352458518763541. doi: 10.1177/1352458518763541. [Epub ahead of print]

PMID:
29532745
34.

Skeletal muscle cells actively shape (auto)immune responses.

Afzali AM, Müntefering T, Wiendl H, Meuth SG, Ruck T.

Autoimmun Rev. 2018 May;17(5):518-529. doi: 10.1016/j.autrev.2017.12.005. Epub 2018 Mar 9. Review.

PMID:
29526638
35.

Treatment choices and neuropsychological symptoms of a large cohort of early MS.

von Bismarck O, Dankowski T, Ambrosius B, Hessler N, Antony G, Ziegler A, Hoshi MM, Aly L, Luessi F, Groppa S, Klotz L, Meuth SG, Tackenberg B, Stoppe M, Then Bergh F, Tumani H, Kümpfel T, Stangel M, Heesen C, Wildemann B, Paul F, Bayas A, Warnke C, Weber F, Linker RA, Ziemann U, Zettl UK, Zipp F, Wiendl H, Hemmer B, Gold R, Salmen A.

Neurol Neuroimmunol Neuroinflamm. 2018 Mar 1;5(3):e446. doi: 10.1212/NXI.0000000000000446. eCollection 2018 May.

36.

Transcriptional Repressor HIC1 Contributes to Suppressive Function of Human Induced Regulatory T Cells.

Ubaid Ullah, Andrabi SBA, Tripathi SK, Dirasantha O, Kanduri K, Rautio S, Gross CC, Lehtimäki S, Bala K, Tuomisto J, Bhatia U, Chakroborty D, Elo LL, Lähdesmäki H, Wiendl H, Rasool O, Lahesmaa R.

Cell Rep. 2018 Feb 20;22(8):2094-2106. doi: 10.1016/j.celrep.2018.01.070.

37.

Sex bias in MHC I-associated shaping of the adaptive immune system.

Schneider-Hohendorf T, Görlich D, Savola P, Kelkka T, Mustjoki S, Gross CC, Owens GC, Klotz L, Dornmair K, Wiendl H, Schwab N.

Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):2168-2173. doi: 10.1073/pnas.1716146115. Epub 2018 Feb 12.

38.

Alemtuzumab Improves Cognitive Processing Speed in Active Multiple Sclerosis-A Longitudinal Observational Study.

Riepl E, Pfeuffer S, Ruck T, Lohmann H, Wiendl H, Meuth SG, Johnen A.

Front Neurol. 2018 Jan 16;8:730. doi: 10.3389/fneur.2017.00730. eCollection 2017.

39.

ECTRIMS/EAN Guideline on the pharmacological treatment of people with multiple sclerosis.

Montalban X, Gold R, Thompson AJ, Otero-Romero S, Amato MP, Chandraratna D, Clanet M, Comi G, Derfuss T, Fazekas F, Hartung HP, Havrdova E, Hemmer B, Kappos L, Liblau R, Lubetzki C, Marcus E, Miller DH, Olsson T, Pilling S, Selmaj K, Siva A, Sorensen PS, Sormani MP, Thalheim C, Wiendl H, Zipp F.

Mult Scler. 2018 Feb;24(2):96-120. doi: 10.1177/1352458517751049. Epub 2018 Jan 20.

PMID:
29353550
40.

ECTRIMS/EAN guideline on the pharmacological treatment of people with multiple sclerosis.

Montalban X, Gold R, Thompson AJ, Otero-Romero S, Amato MP, Chandraratna D, Clanet M, Comi G, Derfuss T, Fazekas F, Hartung HP, Havrdova E, Hemmer B, Kappos L, Liblau R, Lubetzki C, Marcus E, Miller DH, Olsson T, Pilling S, Selmaj K, Siva A, Sorensen PS, Sormani MP, Thalheim C, Wiendl H, Zipp F.

Eur J Neurol. 2018 Feb;25(2):215-237. doi: 10.1111/ene.13536. Epub 2018 Jan 19. Erratum in: Eur J Neurol. 2018 Mar;25(3):605.

PMID:
29352526
41.

Defining response profiles after alemtuzumab: Rare paradoxical disease exacerbation.

Wiendl H, Calabresi PA, Meuth SG.

Neurology. 2018 Feb 13;90(7):309-311. doi: 10.1212/WNL.0000000000004969. Epub 2018 Jan 19. No abstract available.

PMID:
29352097
42.

Infectious risk stratification in multiple sclerosis patients receiving immunotherapy.

Graf J, Leussink VI, Dehmel T, Ringelstein M, Goebels N, Adams O, MacKenzie CR, Warnke C, Feldt T, Lammerskitten A, Klotz L, Meuth S, Wiendl H, Hartung HP, Aktas O, Albrecht P.

Ann Clin Transl Neurol. 2017 Nov 24;4(12):909-914. doi: 10.1002/acn3.491. eCollection 2017 Dec.

43.

Novel pathomechanisms in inflammatory neuropathies.

Schafflick D, Kieseier BC, Wiendl H, Meyer Zu Horste G.

J Neuroinflammation. 2017 Nov 28;14(1):232. doi: 10.1186/s12974-017-1001-8. Review.

44.

NMDAR encephalitis: passive transfer from man to mouse by a recombinant antibody.

Malviya M, Barman S, Golombeck KS, Planagumà J, Mannara F, Strutz-Seebohm N, Wrzos C, Demir F, Baksmeier C, Steckel J, Falk KK, Gross CC, Kovac S, Bönte K, Johnen A, Wandinger KP, Martín-García E, Becker AJ, Elger CE, Klöcker N, Wiendl H, Meuth SG, Hartung HP, Seebohm G, Leypoldt F, Maldonado R, Stadelmann C, Dalmau J, Melzer N, Goebels N.

Ann Clin Transl Neurol. 2017 Oct 3;4(11):768-783. doi: 10.1002/acn3.444. eCollection 2017 Nov.

45.

Defective synaptic transmission causes disease signs in a mouse model of juvenile neuronal ceroid lipofuscinosis.

Grünewald B, Lange MD, Werner C, O'Leary A, Weishaupt A, Popp S, Pearce DA, Wiendl H, Reif A, Pape HC, Toyka KV, Sommer C, Geis C.

Elife. 2017 Nov 14;6. pii: e28685. doi: 10.7554/eLife.28685.

46.

Relevance of raised cerebrospinal fluid monocyte levels in patients with frontotemporal dementia.

Pawlowski M, Lueg G, Gross CC, Johnen A, Krämer J, Weckesser M, Wiendl H, Meuth SG, Duning T.

Neurobiol Aging. 2018 Feb;62:45-52. doi: 10.1016/j.neurobiolaging.2017.09.032. Epub 2017 Oct 13.

PMID:
29107846
47.

Consistent efficacy of daclizumab beta across patient demographic and disease activity subgroups in patients with relapsing-remitting multiple sclerosis.

Rose JW, Giovannoni G, Wiendl H, Gold R, Havrdová E, Kappos L, Selmaj KW, Zhao J, Riester K, Tsao LC, Greenberg SJ.

Mult Scler Relat Disord. 2017 Oct;17:32-40. doi: 10.1016/j.msard.2017.06.006. Epub 2017 Jun 19.

PMID:
29055471
48.

An Enigmatic Case of Acute Mercury Poisoning: Clinical, Immunological Findings and Platelet Function.

Kleffner I, Eichler S, Ruck T, Schüngel L, Pfeuffer S, Polzer P, Dittrich R, Dziewas R, Gross CC, Göbel K, Wiendl H, Kehrel BE, Meuth SG.

Front Neurol. 2017 Sep 28;8:517. doi: 10.3389/fneur.2017.00517. eCollection 2017.

49.

Rivaroxaban ameliorates disease course in an animal model of multiple sclerosis.

Merker M, Eichler S, Herrmann AM, Wiendl H, Kleinschnitz C, Göbel K, Meuth SG.

J Neuroimmunol. 2017 Dec 15;313:125-128. doi: 10.1016/j.jneuroim.2017.08.013. Epub 2017 Sep 21.

PMID:
28992973
50.

Efficacy of daclizumab beta versus intramuscular interferon beta-1a on disability progression across patient demographic and disease activity subgroups in DECIDE.

Cohan S, Kappos L, Giovannoni G, Wiendl H, Selmaj K, Havrdová EK, Rose J, Greenberg S, Phillips G, Ma W, Wang P, Lima G, Sabatella G.

Mult Scler. 2017 Oct 1:1352458517735190. doi: 10.1177/1352458517735190. [Epub ahead of print]

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