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Items: 13

1.

Mesenchymal stem cells alleviate oxidative stress-induced mitochondrial dysfunction in the airways.

Li X, Michaeloudes C, Zhang Y, Wiegman CH, Adcock IM, Lian Q, Mak JCW, Bhavsar PK, Chung KF.

J Allergy Clin Immunol. 2018 May;141(5):1634-1645.e5. doi: 10.1016/j.jaci.2017.08.017. Epub 2017 Sep 11.

PMID:
28911970
2.

BET proteins are a key component of immunoglobulin gene expression.

Shim JM, Lee JS, Russell KE, Wiegman CH, Barnes PJ, Fear D, Adcock IM, Durham AL.

Epigenomics. 2017 Apr;9(4):393-406. doi: 10.2217/epi-2016-0147. Epub 2017 Mar 21.

3.

Animal models of COPD: What do they tell us?

Jones B, Donovan C, Liu G, Gomez HM, Chimankar V, Harrison CL, Wiegman CH, Adcock IM, Knight DA, Hirota JA, Hansbro PM.

Respirology. 2017 Jan;22(1):21-32. doi: 10.1111/resp.12908. Epub 2016 Oct 12. Review.

4.

Mapping physiological G protein-coupled receptor signaling pathways reveals a role for receptor phosphorylation in airway contraction.

Bradley SJ, Wiegman CH, Iglesias MM, Kong KC, Butcher AJ, Plouffe B, Goupil E, Bourgognon JM, Macedo-Hatch T, LeGouill C, Russell K, Laporte SA, K├Ânig GM, Kostenis E, Bouvier M, Chung KF, Amrani Y, Tobin AB.

Proc Natl Acad Sci U S A. 2016 Apr 19;113(16):4524-9. doi: 10.1073/pnas.1521706113. Epub 2016 Apr 8.

5.

The MIF Antagonist ISO-1 Attenuates Corticosteroid-Insensitive Inflammation and Airways Hyperresponsiveness in an Ozone-Induced Model of COPD.

Russell KE, Chung KF, Clarke CJ, Durham AL, Mallia P, Footitt J, Johnston SL, Barnes PJ, Hall SR, Simpson KD, Starkey MR, Hansbro PM, Adcock IM, Wiegman CH.

PLoS One. 2016 Jan 11;11(1):e0146102. doi: 10.1371/journal.pone.0146102. eCollection 2016.

6.

Klotho expression is reduced in COPD airway epithelial cells: effects on inflammation and oxidant injury.

Gao W, Yuan C, Zhang J, Li L, Yu L, Wiegman CH, Barnes PJ, Adcock IM, Huang M, Yao X.

Clin Sci (Lond). 2015 Dec;129(12):1011-23. doi: 10.1042/CS20150273. Epub 2015 Jul 10.

7.

Oxidative stress-induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease.

Wiegman CH, Michaeloudes C, Haji G, Narang P, Clarke CJ, Russell KE, Bao W, Pavlidis S, Barnes PJ, Kanerva J, Bittner A, Rao N, Murphy MP, Kirkham PA, Chung KF, Adcock IM; COPDMAP.

J Allergy Clin Immunol. 2015 Sep;136(3):769-80. doi: 10.1016/j.jaci.2015.01.046. Epub 2015 Mar 29.

8.

Inhibitory effect of hydrogen sulfide on ozone-induced airway inflammation, oxidative stress, and bronchial hyperresponsiveness.

Zhang P, Li F, Wiegman CH, Zhang M, Hong Y, Gong J, Chang Y, Zhang JJ, Adcock I, Chung KF, Zhou X.

Am J Respir Cell Mol Biol. 2015 Jan;52(1):129-37. doi: 10.1165/rcmb.2013-0415OC.

PMID:
25010831
9.

A comprehensive analysis of oxidative stress in the ozone-induced lung inflammation mouse model.

Wiegman CH, Li F, Clarke CJ, Jazrawi E, Kirkham P, Barnes PJ, Adcock IM, Chung KF.

Clin Sci (Lond). 2014 Mar;126(6):425-40. doi: 10.1042/CS20130039.

PMID:
24040961
10.

Hepatic VLDL production in ob/ob mice is not stimulated by massive de novo lipogenesis but is less sensitive to the suppressive effects of insulin.

Wiegman CH, Bandsma RH, Ouwens M, van der Sluijs FH, Havinga R, Boer T, Reijngoud DJ, Romijn JA, Kuipers F.

Diabetes. 2003 May;52(5):1081-9.

11.

Acute inhibition of glucose-6-phosphate translocator activity leads to increased de novo lipogenesis and development of hepatic steatosis without affecting VLDL production in rats.

Bandsma RH, Wiegman CH, Herling AW, Burger HJ, ter Harmsel A, Meijer AJ, Romijn JA, Reijngoud DJ, Kuipers F.

Diabetes. 2001 Nov;50(11):2591-7.

12.

Acute inhibition of hepatic glucose-6-phosphatase does not affect gluconeogenesis but directs gluconeogenic flux toward glycogen in fasted rats. A pharmacological study with the chlorogenic acid derivative S4048.

van Dijk TH, van der Sluijs FH, Wiegman CH, Baller JF, Gustafson LA, Burger HJ, Herling AW, Kuipers F, Meijer AJ, Reijngoud DJ.

J Biol Chem. 2001 Jul 13;276(28):25727-35. Epub 2001 May 9.

13.

Excess portal venous long-chain fatty acids induce syndrome X via HPA axis and sympathetic activation.

Benthem L, Keizer K, Wiegman CH, de Boer SF, Strubbe JH, Steffens AB, Kuipers F, Scheurink AJ.

Am J Physiol Endocrinol Metab. 2000 Dec;279(6):E1286-93.

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