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Items: 30


The YoaW signal peptide directs efficient secretion of different heterologous proteins fused to a StrepII-SUMO tag in Bacillus subtilis.

Heinrich J, Drewniok C, Neugebauer E, Kellner H, Wiegert T.

Microb Cell Fact. 2019 Feb 7;18(1):31. doi: 10.1186/s12934-019-1078-0.


Definition of the σ(W) regulon of Bacillus subtilis in the absence of stress.

Zweers JC, Nicolas P, Wiegert T, van Dijl JM, Denham EL.

PLoS One. 2012;7(11):e48471. doi: 10.1371/journal.pone.0048471. Epub 2012 Nov 14.


Condition-dependent transcriptome reveals high-level regulatory architecture in Bacillus subtilis.

Nicolas P, Mäder U, Dervyn E, Rochat T, Leduc A, Pigeonneau N, Bidnenko E, Marchadier E, Hoebeke M, Aymerich S, Becher D, Bisicchia P, Botella E, Delumeau O, Doherty G, Denham EL, Fogg MJ, Fromion V, Goelzer A, Hansen A, Härtig E, Harwood CR, Homuth G, Jarmer H, Jules M, Klipp E, Le Chat L, Lecointe F, Lewis P, Liebermeister W, March A, Mars RA, Nannapaneni P, Noone D, Pohl S, Rinn B, Rügheimer F, Sappa PK, Samson F, Schaffer M, Schwikowski B, Steil L, Stülke J, Wiegert T, Devine KM, Wilkinson AJ, van Dijl JM, Hecker M, Völker U, Bessières P, Noirot P.

Science. 2012 Mar 2;335(6072):1103-6. doi: 10.1126/science.1206848.


Two proteolytic modules are involved in regulated intramembrane proteolysis of Bacillus subtilis RsiW.

Heinrich J, Hein K, Wiegert T.

Mol Microbiol. 2009 Dec;74(6):1412-26. doi: 10.1111/j.1365-2958.2009.06940.x. Epub 2009 Nov 2.


Stress-responsive systems set specific limits to the overproduction of membrane proteins in Bacillus subtilis.

Zweers JC, Wiegert T, van Dijl JM.

Appl Environ Microbiol. 2009 Dec;75(23):7356-64. doi: 10.1128/AEM.01560-09. Epub 2009 Oct 9.


Regulated intramembrane proteolysis in the control of extracytoplasmic function sigma factors.

Heinrich J, Wiegert T.

Res Microbiol. 2009 Nov;160(9):696-703. doi: 10.1016/j.resmic.2009.08.019. Epub 2009 Sep 22. Review.


The Bacillus subtilis ABC transporter EcsAB influences intramembrane proteolysis through RasP.

Heinrich J, Lundén T, Kontinen VP, Wiegert T.

Microbiology. 2008 Jul;154(Pt 7):1989-97. doi: 10.1099/mic.0.2008/018648-0.


Involvement of Clp protease activity in modulating the Bacillus subtilissigmaw stress response.

Zellmeier S, Schumann W, Wiegert T.

Mol Microbiol. 2006 Sep;61(6):1569-82. Epub 2006 Aug 8.


Identification of sigma(V)-dependent genes of Bacillus subtilis.

Zellmeier S, Hofmann C, Thomas S, Wiegert T, Schumann W.

FEMS Microbiol Lett. 2005 Dec 15;253(2):221-9. Epub 2005 Oct 24.


The Bacillus subtilis sigmaW anti-sigma factor RsiW is degraded by intramembrane proteolysis through YluC.

Schöbel S, Zellmeier S, Schumann W, Wiegert T.

Mol Microbiol. 2004 May;52(4):1091-105.


Analysis of orthologous hrcA genes in Escherichia coli and Bacillus subtilis.

Wiegert T, Hagmaier K, Schumann W.

FEMS Microbiol Lett. 2004 May 1;234(1):9-17.


Analysis of a DNA-binding motif of the Bacillus subtilis HrcA repressor protein.

Wiegert T, Schumann W.

FEMS Microbiol Lett. 2003 Jun 6;223(1):101-6.


Regulation of the Bacillus subtilis heat shock gene htpG is under positive control.

Versteeg S, Escher A, Wende A, Wiegert T, Schumann W.

J Bacteriol. 2003 Jan;185(2):466-74.


Isolation and analysis of mutant alleles of the Bacillus subtilis HrcA repressor with reduced dependency on GroE function.

Reischl S, Wiegert T, Schumann W.

J Biol Chem. 2002 Sep 6;277(36):32659-67. Epub 2002 Jun 24.


Alkaline shock induces the Bacillus subtilis sigma(W) regulon.

Wiegert T, Homuth G, Versteeg S, Schumann W.

Mol Microbiol. 2001 Jul;41(1):59-71.


Cloning and characterization of the major groESL operon from a nitrogen-fixing cyanobacterium Anabaena sp. strain L-31.

Rajaram H, Ballal AD, Apte SK, Wiegert T, Schumann W.

Biochim Biophys Acta. 2001 May 28;1519(1-2):143-6.


SsrA-mediated tagging in Bacillus subtilis.

Wiegert T, Schumann W.

J Bacteriol. 2001 Jul;183(13):3885-9.


Development of a new integration site within the Bacillus subtilis chromosome and construction of compatible expression cassettes.

Härtl B, Wehrl W, Wiegert T, Homuth G, Schumann W.

J Bacteriol. 2001 Apr;183(8):2696-9. Erratum in: J Bacteriol 2001 Jul;183(14):4393.


Specificity of signal peptide recognition in tat-dependent bacterial protein translocation.

Blaudeck N, Sprenger GA, Freudl R, Wiegert T.

J Bacteriol. 2001 Jan;183(2):604-10.


Functional analysis of the secretory precursor processing machinery of Bacillus subtilis: identification of a eubacterial homolog of archaeal and eukaryotic signal peptidases.

Tjalsma H, Bolhuis A, van Roosmalen ML, Wiegert T, Schumann W, Broekhuizen CP, Quax WJ, Venema G, Bron S, van Dijl JM.

Genes Dev. 1998 Aug 1;12(15):2318-31.


The Helicobacter felis ftsH gene encoding an ATP-dependent metalloprotease can replace the Escherichia coli homologue for growth and phage lambda lysogenization.

Melchers K, Wiegert T, Buhmann A, Postius S, Schäfer KP, Schumann W.

Arch Microbiol. 1998 May;169(5):393-6.


Identification of a thiamin-dependent synthase in Escherichia coli required for the formation of the 1-deoxy-D-xylulose 5-phosphate precursor to isoprenoids, thiamin, and pyridoxol.

Sprenger GA, Schörken U, Wiegert T, Grolle S, de Graaf AA, Taylor SV, Begley TP, Bringer-Meyer S, Sahm H.

Proc Natl Acad Sci U S A. 1997 Nov 25;94(24):12857-62.


Export of the periplasmic NADP-containing glucose-fructose oxidoreductase of Zymomonas mobilis.

Wiegert T, Sahm H, Sprenger GA.

Arch Microbiol. 1996 Jul;166(1):32-41.


Chronic pain: economic, psychosocial, ethical, preventive, and medical aspects.

Marciani RD, Humphries LL, Maxwell EN Jr, Costich JF, Wiegert T, Engelberg J.

South Med J. 1985 Jun;78(6):719-24. No abstract available.


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