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Items: 1 to 50 of 100

1.

The inhibitor apoptosis protein antagonist Debio 1143 Is an attractive HIV-1 latency reversal candidate.

Bobardt M, Kuo J, Chatterji U, Chanda S, Little SJ, Wiedemann N, Vuagniaux G, Gallay PA.

PLoS One. 2019 Feb 4;14(2):e0211746. doi: 10.1371/journal.pone.0211746. eCollection 2019.

2.

Mitochondrial proteins: from biogenesis to functional networks.

Pfanner N, Warscheid B, Wiedemann N.

Nat Rev Mol Cell Biol. 2019 May;20(5):267-284. doi: 10.1038/s41580-018-0092-0. Review.

PMID:
30626975
3.

DEBIO 1143, an IAP inhibitor, reverses carboplatin resistance in ovarian cancer cells and triggers apoptotic or necroptotic cell death.

Thibault B, Genre L, Le Naour A, Broca C, Mery E, Vuagniaux G, Delord JP, Wiedemann N, Couderc B.

Sci Rep. 2018 Dec 14;8(1):17862. doi: 10.1038/s41598-018-35860-z.

4.

Structural Basis of Membrane Protein Chaperoning through the Mitochondrial Intermembrane Space.

Weinhäupl K, Lindau C, Hessel A, Wang Y, Schütze C, Jores T, Melchionda L, Schönfisch B, Kalbacher H, Bersch B, Rapaport D, Brennich M, Lindorff-Larsen K, Wiedemann N, Schanda P.

Cell. 2018 Nov 15;175(5):1365-1379.e25. doi: 10.1016/j.cell.2018.10.039.

5.

SMAC Mimetic Debio 1143 and Ablative Radiation Therapy Synergize to Enhance Antitumor Immunity against Lung Cancer.

Tao Z, McCall NS, Wiedemann N, Vuagniaux G, Yuan Z, Lu B.

Clin Cancer Res. 2019 Feb 1;25(3):1113-1124. doi: 10.1158/1078-0432.CCR-17-3852. Epub 2018 Oct 23.

PMID:
30352911
6.

Complete Native Stable Isotope Labeling by Amino Acids of Saccharomyces cerevisiae for Global Proteomic Analysis.

Dannenmaier S, Stiller SB, Morgenstern M, Lübbert P, Oeljeklaus S, Wiedemann N, Warscheid B.

Anal Chem. 2018 Sep 4;90(17):10501-10509. doi: 10.1021/acs.analchem.8b02557. Epub 2018 Aug 23.

7.

The mitochondrial transporter SLC25A25 links ciliary TRPP2 signaling and cellular metabolism.

Hofherr A, Seger C, Fitzpatrick F, Busch T, Michel E, Luan J, Osterried L, Linden F, Kramer-Zucker A, Wakimoto B, Schütze C, Wiedemann N, Artati A, Adamski J, Walz G, Kunji ERS, Montell C, Watnick T, Köttgen M.

PLoS Biol. 2018 Aug 6;16(8):e2005651. doi: 10.1371/journal.pbio.2005651. eCollection 2018 Aug.

8.

Metabolic profiling of isolated mitochondria and cytoplasm reveals compartment-specific metabolic responses.

Pan D, Lindau C, Lagies S, Wiedemann N, Kammerer B.

Metabolomics. 2018;14(5):59. doi: 10.1007/s11306-018-1352-x. Epub 2018 Mar 31.

9.

Respiratory Chain Supercomplexes associate with the Cysteine Desulfurase Complex of the Iron-Sulfur Cluster Assembly Machinery.

Böttinger L, Mårtensson CU, Song J, Zufall N, Wiedemann N, Becker T.

Mol Biol Cell. 2018 Jan 31. pii: mbc.E17-09-0555. doi: 10.1091/mbc.E17-09-0555. [Epub ahead of print]

10.

Training the next generation of psychotraumatologists: COllaborative Network for Training and EXcellence in psychoTraumatology (CONTEXT).

Vallières F, Hyland P, Murphy J, Hansen M, Shevlin M, Elklit A, Ceannt R, Armour C, Wiedemann N, Munk M, Dinesen C, O'Hare G, Cunningham T, Askerod D, Spitz P, Blackwell N, McCarthy A, O'Dowd L, Scott S, Reid T, Mokake A, Halpin R, Perera C, Gleeson C, Frost R, Flanagan N, Aldamman K, Tamrakar T, Louison Vang M, Sherwood L, Travers Á, Haahr-Pedersen I, Walshe C, McDonagh T, Bramsen RH.

Eur J Psychotraumatol. 2018 Jan 16;9(1):1421001. doi: 10.1080/20008198.2017.1421001. eCollection 2018.

11.

Membrane protein insertion through a mitochondrial β-barrel gate.

Höhr AIC, Lindau C, Wirth C, Qiu J, Stroud DA, Kutik S, Guiard B, Hunte C, Becker T, Pfanner N, Wiedemann N.

Science. 2018 Jan 19;359(6373). pii: eaah6834. doi: 10.1126/science.aah6834.

12.

Assessment of a bedside test for N-terminal pro B-type natriuretic peptide (NT-proBNP) to differentiate cardiac from non-cardiac causes of pleural effusion in cats.

Wurtinger G, Henrich E, Hildebrandt N, Wiedemann N, Schneider M, Hassdenteufel E.

BMC Vet Res. 2017 Dec 20;13(1):394. doi: 10.1186/s12917-017-1319-6.

13.

Strengthening mental health care systems for Syrian refugees in Europe and the Middle East: integrating scalable psychological interventions in eight countries.

Sijbrandij M, Acarturk C, Bird M, Bryant RA, Burchert S, Carswell K, de Jong J, Dinesen C, Dawson KS, El Chammay R, van Ittersum L, Jordans M, Knaevelsrud C, McDaid D, Miller K, Morina N, Park AL, Roberts B, van Son Y, Sondorp E, Pfaltz MC, Ruttenberg L, Schick M, Schnyder U, van Ommeren M, Ventevogel P, Weissbecker I, Weitz E, Wiedemann N, Whitney C, Cuijpers P.

Eur J Psychotraumatol. 2017 Nov 7;8(sup2):1388102. doi: 10.1080/20008198.2017.1388102. eCollection 2017. Review.

14.

Identification of new channels by systematic analysis of the mitochondrial outer membrane.

Krüger V, Becker T, Becker L, Montilla-Martinez M, Ellenrieder L, Vögtle FN, Meyer HE, Ryan MT, Wiedemann N, Warscheid B, Pfanner N, Wagner R, Meisinger C.

J Cell Biol. 2017 Nov 6;216(11):3485-3495. doi: 10.1083/jcb.201706043. Epub 2017 Sep 15.

15.

[Cyanosis in a calf with a double outlet right ventricle].

Wiedemann N, Hildebrandt N, Henrich M, Henrich E, Schneider M.

Tierarztl Prax Ausg G Grosstiere Nutztiere. 2017 Sep 13;45(5). doi: 10.15653/TPG-161077. [Epub ahead of print] German.

PMID:
28905979
16.

Definition of a High-Confidence Mitochondrial Proteome at Quantitative Scale.

Morgenstern M, Stiller SB, Lübbert P, Peikert CD, Dannenmaier S, Drepper F, Weill U, Höß P, Feuerstein R, Gebert M, Bohnert M, van der Laan M, Schuldiner M, Schütze C, Oeljeklaus S, Pfanner N, Wiedemann N, Warscheid B.

Cell Rep. 2017 Jun 27;19(13):2836-2852. doi: 10.1016/j.celrep.2017.06.014.

17.

Follow-up of troponin I concentration in dogs with atrioventricular block and dual-chamber pacing in a case-matched study.

Wiedemann N, Hildebrandt N, Wurtinger G, Henrich E, Hassdenteufel E, Schneider M.

J Vet Cardiol. 2017 Jun;19(3):247-255. doi: 10.1016/j.jvc.2017.01.004. Epub 2017 May 4.

PMID:
28478942
18.

Mitochondrial Machineries for Protein Import and Assembly.

Wiedemann N, Pfanner N.

Annu Rev Biochem. 2017 Jun 20;86:685-714. doi: 10.1146/annurev-biochem-060815-014352. Epub 2017 Mar 15. Review.

PMID:
28301740
19.

Behavioral responses to noxious stimuli shape the perception of pain.

May ES, Tiemann L, Schmidt P, Nickel MM, Wiedemann N, Dresel C, Sorg C, Ploner M.

Sci Rep. 2017 Mar 9;7:44083. doi: 10.1038/srep44083.

20.

Separating mitochondrial protein assembly and endoplasmic reticulum tethering by selective coupling of Mdm10.

Ellenrieder L, Opaliński Ł, Becker L, Krüger V, Mirus O, Straub SP, Ebell K, Flinner N, Stiller SB, Guiard B, Meisinger C, Wiedemann N, Schleiff E, Wagner R, Pfanner N, Becker T.

Nat Commun. 2016 Oct 10;7:13021. doi: 10.1038/ncomms13021.

21.

Dynamic organization of the mitochondrial protein import machinery.

Straub SP, Stiller SB, Wiedemann N, Pfanner N.

Biol Chem. 2016 Nov 1;397(11):1097-1114. doi: 10.1515/hsz-2016-0145. Review.

PMID:
27289000
22.

Mitochondrial OXA Translocase Plays a Major Role in Biogenesis of Inner-Membrane Proteins.

Stiller SB, Höpker J, Oeljeklaus S, Schütze C, Schrempp SG, Vent-Schmidt J, Horvath SE, Frazier AE, Gebert N, van der Laan M, Bohnert M, Warscheid B, Pfanner N, Wiedemann N.

Cell Metab. 2016 May 10;23(5):901-8. doi: 10.1016/j.cmet.2016.04.005.

23.

One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy.

Yofe I, Weill U, Meurer M, Chuartzman S, Zalckvar E, Goldman O, Ben-Dor S, Schütze C, Wiedemann N, Knop M, Khmelinskii A, Schuldiner M.

Nat Methods. 2016 Apr;13(4):371-378. doi: 10.1038/nmeth.3795. Epub 2016 Feb 29.

24.

BCL9/9L-β-catenin Signaling is Associated With Poor Outcome in Colorectal Cancer.

Moor AE, Anderle P, Cantù C, Rodriguez P, Wiedemann N, Baruthio F, Deka J, André S, Valenta T, Moor MB, Győrffy B, Barras D, Delorenzi M, Basler K, Aguet M.

EBioMedicine. 2015 Oct 30;2(12):1932-43. doi: 10.1016/j.ebiom.2015.10.030. eCollection 2015 Dec.

25.

SMAC mimetic Debio 1143 synergizes with taxanes, topoisomerase inhibitors and bromodomain inhibitors to impede growth of lung adenocarcinoma cells.

Langdon CG, Wiedemann N, Held MA, Mamillapalli R, Iyidogan P, Theodosakis N, Platt JT, Levy F, Vuagniaux G, Wang S, Bosenberg MW, Stern DF.

Oncotarget. 2015 Nov 10;6(35):37410-25. doi: 10.18632/oncotarget.6138.

26.

Sam37 is crucial for formation of the mitochondrial TOM-SAM supercomplex, thereby promoting β-barrel biogenesis.

Wenz LS, Ellenrieder L, Qiu J, Bohnert M, Zufall N, van der Laan M, Pfanner N, Wiedemann N, Becker T.

J Cell Biol. 2015 Sep 28;210(7):1047-54. doi: 10.1083/jcb.201504119.

27.

Molecular architecture of the active mitochondrial protein gate.

Shiota T, Imai K, Qiu J, Hewitt VL, Tan K, Shen HH, Sakiyama N, Fukasawa Y, Hayat S, Kamiya M, Elofsson A, Tomii K, Horton P, Wiedemann N, Pfanner N, Lithgow T, Endo T.

Science. 2015 Sep 25;349(6255):1544-8. doi: 10.1126/science.aac6428.

PMID:
26404837
28.

The fusogenic lipid phosphatidic acid promotes the biogenesis of mitochondrial outer membrane protein Ugo1.

Vögtle FN, Keller M, Taskin AA, Horvath SE, Guan XL, Prinz C, Opalińska M, Zorzin C, van der Laan M, Wenk MR, Schubert R, Wiedemann N, Holzer M, Meisinger C.

J Cell Biol. 2015 Sep 14;210(6):951-60.

29.

Lam6 Regulates the Extent of Contacts between Organelles.

Elbaz-Alon Y, Eisenberg-Bord M, Shinder V, Stiller SB, Shimoni E, Wiedemann N, Geiger T, Schuldiner M.

Cell Rep. 2015 Jul 7;12(1):7-14. doi: 10.1016/j.celrep.2015.06.022. Epub 2015 Jun 25.

30.

The radiosensitizing activity of the SMAC-mimetic, Debio 1143, is TNFα-mediated in head and neck squamous cell carcinoma.

Matzinger O, Viertl D, Tsoutsou P, Kadi L, Rigotti S, Zanna C, Wiedemann N, Vozenin MC, Vuagniaux G, Bourhis J.

Radiother Oncol. 2015 Sep;116(3):495-503. doi: 10.1016/j.radonc.2015.05.017. Epub 2015 Jun 18.

PMID:
26096848
31.

Retro-translocation of mitochondrial intermembrane space proteins.

Bragoszewski P, Wasilewski M, Sakowska P, Gornicka A, Böttinger L, Qiu J, Wiedemann N, Chacinska A.

Proc Natl Acad Sci U S A. 2015 Jun 23;112(25):7713-8. doi: 10.1073/pnas.1504615112. Epub 2015 Jun 8.

32.

Cooperation of protein machineries in mitochondrial protein sorting.

Wenz LS, Opaliński Ł, Wiedemann N, Becker T.

Biochim Biophys Acta. 2015 May;1853(5):1119-29. doi: 10.1016/j.bbamcr.2015.01.012. Epub 2015 Jan 26. Review.

33.

Assembly of β-barrel proteins in the mitochondrial outer membrane.

Höhr AI, Straub SP, Warscheid B, Becker T, Wiedemann N.

Biochim Biophys Acta. 2015 Jan;1853(1):74-88. doi: 10.1016/j.bbamcr.2014.10.006. Epub 2014 Oct 8. Review.

34.

Amyloid-β peptide induces mitochondrial dysfunction by inhibition of preprotein maturation.

Mossmann D, Vögtle FN, Taskin AA, Teixeira PF, Ring J, Burkhart JM, Burger N, Pinho CM, Tadic J, Loreth D, Graff C, Metzger F, Sickmann A, Kretz O, Wiedemann N, Zahedi RP, Madeo F, Glaser E, Meisinger C.

Cell Metab. 2014 Oct 7;20(4):662-9. doi: 10.1016/j.cmet.2014.07.024. Epub 2014 Aug 28.

35.

The presequence pathway is involved in protein sorting to the mitochondrial outer membrane.

Wenz LS, Opaliński L, Schuler MH, Ellenrieder L, Ieva R, Böttinger L, Qiu J, van der Laan M, Wiedemann N, Guiard B, Pfanner N, Becker T.

EMBO Rep. 2014 Jun;15(6):678-85. doi: 10.1002/embr.201338144. Epub 2014 Apr 29.

36.

Biogenesis and folding of β-barrel membrane proteins.

Wenz LS, Qiu J, Becker T, Wiedemann N.

Cell Cycle. 2014;13(2):169-70. doi: 10.4161/cc.27035. Epub 2013 Nov 15. No abstract available.

37.

Coupling of mitochondrial import and export translocases by receptor-mediated supercomplex formation.

Qiu J, Wenz LS, Zerbes RM, Oeljeklaus S, Bohnert M, Stroud DA, Wirth C, Ellenrieder L, Thornton N, Kutik S, Wiese S, Schulze-Specking A, Zufall N, Chacinska A, Guiard B, Hunte C, Warscheid B, van der Laan M, Pfanner N, Wiedemann N, Becker T.

Cell. 2013 Aug 1;154(3):596-608. doi: 10.1016/j.cell.2013.06.033.

38.

A complex of Cox4 and mitochondrial Hsp70 plays an important role in the assembly of the cytochrome c oxidase.

Böttinger L, Guiard B, Oeljeklaus S, Kulawiak B, Zufall N, Wiedemann N, Warscheid B, van der Laan M, Becker T.

Mol Biol Cell. 2013 Sep;24(17):2609-19. doi: 10.1091/mbc.E13-02-0106. Epub 2013 Jul 17.

39.

Activation and degradation of mitofusins: two pathways regulate mitochondrial fusion by reversible ubiquitylation.

Wiedemann N, Stiller SB, Pfanner N.

Mol Cell. 2013 Feb 7;49(3):423-5. doi: 10.1016/j.molcel.2013.01.027.

40.

The mitochondrial protein import machinery has multiple connections to the respiratory chain.

Kulawiak B, Höpker J, Gebert M, Guiard B, Wiedemann N, Gebert N.

Biochim Biophys Acta. 2013 May;1827(5):612-26. doi: 10.1016/j.bbabio.2012.12.004. Epub 2012 Dec 26. Review.

41.

The channel-forming Sym1 protein is transported by the TIM23 complex in a presequence-independent manner.

Reinhold R, Krüger V, Meinecke M, Schulz C, Schmidt B, Grunau SD, Guiard B, Wiedemann N, van der Laan M, Wagner R, Rehling P, Dudek J.

Mol Cell Biol. 2012 Dec;32(24):5009-21. doi: 10.1128/MCB.00843-12. Epub 2012 Oct 8.

42.

Processing and topology of the yeast mitochondrial phosphatidylserine decarboxylase 1.

Horvath SE, Böttinger L, Vögtle FN, Wiedemann N, Meisinger C, Becker T, Daum G.

J Biol Chem. 2012 Oct 26;287(44):36744-55. doi: 10.1074/jbc.M112.398107. Epub 2012 Sep 13.

43.

Role of mitochondrial inner membrane organizing system in protein biogenesis of the mitochondrial outer membrane.

Bohnert M, Wenz LS, Zerbes RM, Horvath SE, Stroud DA, von der Malsburg K, Müller JM, Oeljeklaus S, Perschil I, Warscheid B, Chacinska A, Veenhuis M, van der Klei IJ, Daum G, Wiedemann N, Becker T, Pfanner N, van der Laan M.

Mol Biol Cell. 2012 Oct;23(20):3948-56. doi: 10.1091/mbc.E12-04-0295. Epub 2012 Aug 23.

44.

Role of MINOS in mitochondrial membrane architecture: cristae morphology and outer membrane interactions differentially depend on mitofilin domains.

Zerbes RM, Bohnert M, Stroud DA, von der Malsburg K, Kram A, Oeljeklaus S, Warscheid B, Becker T, Wiedemann N, Veenhuis M, van der Klei IJ, Pfanner N, van der Laan M.

J Mol Biol. 2012 Sep 14;422(2):183-91. doi: 10.1016/j.jmb.2012.05.004. Epub 2012 May 7.

45.

Role of MINOS in mitochondrial membrane architecture and biogenesis.

van der Laan M, Bohnert M, Wiedemann N, Pfanner N.

Trends Cell Biol. 2012 Apr;22(4):185-92. doi: 10.1016/j.tcb.2012.01.004. Epub 2012 Mar 2.

PMID:
22386790
46.

Gastrointestinal quality of life after laparoscopic-assisted sigmoidectomy for diverticular disease.

Pasternak I, Wiedemann N, Basilicata G, Melcher GA.

Int J Colorectal Dis. 2012 Jun;27(6):781-7. doi: 10.1007/s00384-011-1386-2. Epub 2011 Dec 28.

PMID:
22200793
47.

Dual function of Sdh3 in the respiratory chain and TIM22 protein translocase of the mitochondrial inner membrane.

Gebert N, Gebert M, Oeljeklaus S, von der Malsburg K, Stroud DA, Kulawiak B, Wirth C, Zahedi RP, Dolezal P, Wiese S, Simon O, Schulze-Specking A, Truscott KN, Sickmann A, Rehling P, Guiard B, Hunte C, Warscheid B, van der Laan M, Pfanner N, Wiedemann N.

Mol Cell. 2011 Dec 9;44(5):811-8. doi: 10.1016/j.molcel.2011.09.025.

48.

Composition and topology of the endoplasmic reticulum-mitochondria encounter structure.

Stroud DA, Oeljeklaus S, Wiese S, Bohnert M, Lewandrowski U, Sickmann A, Guiard B, van der Laan M, Warscheid B, Wiedemann N.

J Mol Biol. 2011 Nov 4;413(4):743-50. doi: 10.1016/j.jmb.2011.09.012. Epub 2011 Sep 16.

PMID:
21945531
49.

Structural basis for the function of Tim50 in the mitochondrial presequence translocase.

Qian X, Gebert M, Höpker J, Yan M, Li J, Wiedemann N, van der Laan M, Pfanner N, Sha B.

J Mol Biol. 2011 Aug 19;411(3):513-9. doi: 10.1016/j.jmb.2011.06.020. Epub 2011 Jun 17.

50.

Biogenesis of mitochondrial β-barrel proteins: the POTRA domain is involved in precursor release from the SAM complex.

Stroud DA, Becker T, Qiu J, Stojanovski D, Pfannschmidt S, Wirth C, Hunte C, Guiard B, Meisinger C, Pfanner N, Wiedemann N.

Mol Biol Cell. 2011 Aug 15;22(16):2823-33. doi: 10.1091/mbc.E11-02-0148. Epub 2011 Jun 16.

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