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Items: 17


Towards a solution to MERS: protective human monoclonal antibodies targeting different domains and functions of the MERS-coronavirus spike glycoprotein.

Widjaja I, Wang C, van Haperen R, Gutiérrez-Álvarez J, van Dieren B, Okba NMA, Raj VS, Li W, Fernandez-Delgado R, Grosveld F, van Kuppeveld FJM, Haagmans BL, Enjuanes L, Drabek D, Bosch BJ.

Emerg Microbes Infect. 2019;8(1):516-530. doi: 10.1080/22221751.2019.1597644.


Chimeric camel/human heavy-chain antibodies protect against MERS-CoV infection.

Stalin Raj V, Okba NMA, Gutierrez-Alvarez J, Drabek D, van Dieren B, Widagdo W, Lamers MM, Widjaja I, Fernandez-Delgado R, Sola I, Bensaid A, Koopmans MP, Segalés J, Osterhaus ADME, Bosch BJ, Enjuanes L, Haagmans BL.

Sci Adv. 2018 Aug 8;4(8):eaas9667. doi: 10.1126/sciadv.aas9667. eCollection 2018 Aug.


Broad receptor engagement of an emerging global coronavirus may potentiate its diverse cross-species transmissibility.

Li W, Hulswit RJG, Kenney SP, Widjaja I, Jung K, Alhamo MA, van Dieren B, van Kuppeveld FJM, Saif LJ, Bosch BJ.

Proc Natl Acad Sci U S A. 2018 May 29;115(22):E5135-E5143. doi: 10.1073/pnas.1802879115. Epub 2018 May 14.


Identification of sialic acid-binding function for the Middle East respiratory syndrome coronavirus spike glycoprotein.

Li W, Hulswit RJG, Widjaja I, Raj VS, McBride R, Peng W, Widagdo W, Tortorici MA, van Dieren B, Lang Y, van Lent JWM, Paulson JC, de Haan CAM, de Groot RJ, van Kuppeveld FJM, Haagmans BL, Bosch BJ.

Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8508-E8517. doi: 10.1073/pnas.1712592114. Epub 2017 Sep 18.


Characteristics of RSV-Specific Maternal Antibodies in Plasma of Hospitalized, Acute RSV Patients under Three Months of Age.

Jans J, Wicht O, Widjaja I, Ahout IM, de Groot R, Guichelaar T, Luytjes W, de Jonge MI, de Haan CA, Ferwerda G.

PLoS One. 2017 Jan 30;12(1):e0170877. doi: 10.1371/journal.pone.0170877. eCollection 2017.


Characterization of Epitope-Specific Anti-Respiratory Syncytial Virus (Anti-RSV) Antibody Responses after Natural Infection and after Vaccination with Formalin-Inactivated RSV.

Widjaja I, Wicht O, Luytjes W, Leenhouts K, Rottier PJM, van Kuppeveld FJM, Haijema BJ, de Haan CAM.

J Virol. 2016 Jun 10;90(13):5965-5977. doi: 10.1128/JVI.00235-16. Print 2016 Jul 1.


In silico structure-based design and synthesis of novel anti-RSV compounds.

Cancellieri M, Bassetto M, Widjaja I, van Kuppeveld F, de Haan CA, Brancale A.

Antiviral Res. 2015 Oct;122:46-50. doi: 10.1016/j.antiviral.2015.08.003. Epub 2015 Aug 8.


Recombinant Soluble Respiratory Syncytial Virus F Protein That Lacks Heptad Repeat B, Contains a GCN4 Trimerization Motif and Is Not Cleaved Displays Prefusion-Like Characteristics.

Widjaja I, Rigter A, Jacobino S, van Kuppeveld FJ, Leenhouts K, Palomo C, Melero JA, Leusen JH, Haijema BJ, Rottier PJ, de Haan CA.

PLoS One. 2015 Jun 24;10(6):e0130829. doi: 10.1371/journal.pone.0130829. eCollection 2015.


A protective and safe intranasal RSV vaccine based on a recombinant prefusion-like form of the F protein bound to bacterium-like particles.

Rigter A, Widjaja I, Versantvoort H, Coenjaerts FE, van Roosmalen M, Leenhouts K, Rottier PJ, Haijema BJ, de Haan CA.

PLoS One. 2013 Aug 12;8(8):e71072. doi: 10.1371/journal.pone.0071072. eCollection 2013.


Competition between influenza A virus genome segments.

Widjaja I, de Vries E, Rottier PJ, de Haan CA.

PLoS One. 2012;7(10):e47529. doi: 10.1371/journal.pone.0047529. Epub 2012 Oct 11.


Inhibition of the ubiquitin-proteasome system affects influenza A virus infection at a postfusion step.

Widjaja I, de Vries E, Tscherne DM, García-Sastre A, Rottier PJ, de Haan CA.

J Virol. 2010 Sep;84(18):9625-31. doi: 10.1128/JVI.01048-10. Epub 2010 Jul 14.


A protein phosphatase 2C, responsive to the bacterial effector AvrRpm1 but not to the AvrB effector, regulates defense responses in Arabidopsis.

Widjaja I, Lassowskat I, Bethke G, Eschen-Lippold L, Long HH, Naumann K, Dangl JL, Scheel D, Lee J.

Plant J. 2010 Jan;61(2):249-58. doi: 10.1111/j.1365-313X.2009.04047.x. Epub 2009 Oct 16.


Combining subproteome enrichment and Rubisco depletion enables identification of low abundance proteins differentially regulated during plant defense.

Widjaja I, Naumann K, Roth U, Wolf N, Mackey D, Dangl JL, Scheel D, Lee J.

Proteomics. 2009 Jan;9(1):138-47. doi: 10.1002/pmic.200800293.


Comparative proteomics of Cannabis sativa plant tissues.

Raharjo TJ, Widjaja I, Roytrakul S, Verpoorte R.

J Biomol Tech. 2004 Jun;15(2):97-106.


Glucosylation of salicyl alcohol by cell suspension cultures of Solanum laciniatum.

Syahrani A, Widjaja I, Indrayanto G, Wilkins AL.

J Asian Nat Prod Res. 1998;1(2):111-7.


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