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Items: 1 to 50 of 86

1.

Super-resolution microscopy can identify specific protein distribution patterns in platelets incubated with cancer cells.

Bergstrand J, Xu L, Miao X, Li N, Öktem O, Franzén B, Auer G, Lomnytska M, Widengren J.

Nanoscale. 2019 May 28;11(20):10023-10033. doi: 10.1039/c9nr01967g. Epub 2019 May 14.

PMID:
31086875
2.

On the decay time of upconversion luminescence.

Bergstrand J, Liu Q, Huang B, Peng X, Würth C, Resch-Genger U, Zhan Q, Widengren J, Ågren H, Liu H.

Nanoscale. 2019 Mar 14;11(11):4959-4969. doi: 10.1039/c8nr10332a.

PMID:
30839016
3.

Fast upconversion super-resolution microscopy with 10 μs per pixel dwell times.

Peng X, Huang B, Pu R, Liu H, Zhang T, Widengren J, Zhan Q, Ågren H.

Nanoscale. 2019 Jan 23;11(4):1563-1569. doi: 10.1039/c8nr08986h.

PMID:
30644963
4.

Overtone Vibrational Transition-Induced Lanthanide Excited-State Quenching in Yb3+/Er3+-Doped Upconversion Nanocrystals.

Huang B, Bergstrand J, Duan S, Zhan Q, Widengren J, Ågren H, Liu H.

ACS Nano. 2018 Nov 27;12(11):10572-10575. doi: 10.1021/acsnano.8b05095. No abstract available.

PMID:
30481966
5.

Factor H binding proteins protect division septa on encapsulated Streptococcus pneumoniae against complement C3b deposition and amplification.

Pathak A, Bergstrand J, Sender V, Spelmink L, Aschtgen MS, Muschiol S, Widengren J, Henriques-Normark B.

Nat Commun. 2018 Aug 23;9(1):3398. doi: 10.1038/s41467-018-05494-w.

6.

In Situ Monitoring of p53 Protein and MDM2 Protein Interaction in Single Living Cells Using Single-Molecule Fluorescence Spectroscopy.

Du Z, Yu J, Li F, Deng L, Wu F, Huang X, Bergstrand J, Widengren J, Dong C, Ren J.

Anal Chem. 2018 May 15;90(10):6144-6151. doi: 10.1021/acs.analchem.8b00473. Epub 2018 Apr 26.

PMID:
29671327
7.

Nanoscale localization of proteins within focal adhesions indicates discrete functional assemblies with selective force-dependence.

Xu L, Braun LJ, Rönnlund D, Widengren J, Aspenström P, Gad AKB.

FEBS J. 2018 May;285(9):1635-1652. doi: 10.1111/febs.14433. Epub 2018 Mar 30.

8.

Platelet protein biomarker panel for ovarian cancer diagnosis.

Lomnytska M, Pinto R, Becker S, Engström U, Gustafsson S, Björklund C, Templin M, Bergstrand J, Xu L, Widengren J, Epstein E, Franzén B, Auer G.

Biomark Res. 2018 Jan 12;6:2. doi: 10.1186/s40364-018-0118-y. eCollection 2018.

9.
10.

Label-free monitoring of ambient oxygenation and redox conditions using the photodynamics of flavin compounds and transient state (TRAST) spectroscopy.

Tornmalm J, Widengren J.

Methods. 2018 May 1;140-141:178-187. doi: 10.1016/j.ymeth.2017.11.013. Epub 2017 Nov 24.

11.

Characterization of the Role of the Malate Dehydrogenases to Lung Tumor Cell Survival.

Zhang B, Tornmalm J, Widengren J, Vakifahmetoglu-Norberg H, Norberg E.

J Cancer. 2017 Jul 5;8(11):2088-2096. doi: 10.7150/jca.19373. eCollection 2017.

12.

The lateral distance between a proton pump and ATP synthase determines the ATP-synthesis rate.

Sjöholm J, Bergstrand J, Nilsson T, Šachl R, Ballmoos CV, Widengren J, Brzezinski P.

Sci Rep. 2017 Jun 7;7(1):2926. doi: 10.1038/s41598-017-02836-4.

13.

pIgR and PECAM-1 bind to pneumococcal adhesins RrgA and PspC mediating bacterial brain invasion.

Iovino F, Engelen-Lee JY, Brouwer M, van de Beek D, van der Ende A, Valls Seron M, Mellroth P, Muschiol S, Bergstrand J, Widengren J, Henriques-Normark B.

J Exp Med. 2017 Jun 5;214(6):1619-1630. doi: 10.1084/jem.20161668. Epub 2017 May 17.

14.

Stimulated Emission Depletion Microscopy.

Blom H, Widengren J.

Chem Rev. 2017 Jun 14;117(11):7377-7427. doi: 10.1021/acs.chemrev.6b00653. Epub 2017 Mar 6. Review.

PMID:
28262022
15.

Catalytic Conversion of Lipophilic Substrates by Phase constrained Enzymes in the Aqueous or in the Membrane Phase.

Cebula M, Turan IS, Sjödin B, Thulasingam M, Brock J, Chmyrov V, Widengren J, Abe H, Mannervik B, Haeggström JZ, Rinaldo-Matthis A, Akkaya EU, Morgenstern R.

Sci Rep. 2016 Dec 5;6:38316. doi: 10.1038/srep38316.

16.
17.

MHC I Expression Regulates Co-clustering and Mobility of Interleukin-2 and -15 Receptors in T Cells.

Mocsár G, Volkó J, Rönnlund D, Widengren J, Nagy P, Szöllősi J, Tóth K, Goldman CK, Damjanovich S, Waldmann TA, Bodnár A, Vámosi G.

Biophys J. 2016 Jul 12;111(1):100-12. doi: 10.1016/j.bpj.2016.05.044.

18.

Protonation Dynamics on Lipid Nanodiscs: Influence of the Membrane Surface Area and External Buffers.

Xu L, Öjemyr LN, Bergstrand J, Brzezinski P, Widengren J.

Biophys J. 2016 May 10;110(9):1993-2003. doi: 10.1016/j.bpj.2016.03.035.

19.

Cytokines Induce Faster Membrane Diffusion of MHC Class I and the Ly49A Receptor in a Subpopulation of Natural Killer Cells.

Bagawath-Singh S, Staaf E, Stoppelenburg AJ, Spielmann T, Kambayashi T, Widengren J, Johansson S.

Front Immunol. 2016 Feb 4;7:16. doi: 10.3389/fimmu.2016.00016. eCollection 2016.

20.

Label-Free Fluctuation Spectroscopy Based on Coherent Anti-Stokes Raman Scattering from Bulk Water Molecules.

Rabasovic MD, Sisamakis E, Wennmalm S, Widengren J.

Chemphyschem. 2016 Apr 4;17(7):1025-33. doi: 10.1002/cphc.201501129. Epub 2016 Feb 11.

21.

Resolution, target density and labeling effects in colocalization studies - suppression of false positives by nanoscopy and modified algorithms.

Xu L, Rönnlund D, Aspenström P, Braun LJ, Gad AK, Widengren J.

FEBS J. 2016 Mar;283(5):882-98. doi: 10.1111/febs.13652. Epub 2016 Feb 5.

22.

Highly Sensitive FRET-FCS Detects Amyloid β-Peptide Oligomers in Solution at Physiological Concentrations.

Wennmalm S, Chmyrov V, Widengren J, Tjernberg L.

Anal Chem. 2015 Dec 1;87(23):11700-5. doi: 10.1021/acs.analchem.5b02630. Epub 2015 Nov 10.

PMID:
26489794
23.

Mechanisms of fluorescence decays of colloidal CdSe-CdS/ZnS quantum dots unraveled by time-resolved fluorescence measurement.

Xu H, Chmyrov V, Widengren J, Brismar H, Fu Y.

Phys Chem Chem Phys. 2015 Nov 7;17(41):27588-95. doi: 10.1039/c5cp03109e.

PMID:
26426293
24.

Trans-cis isomerization of lipophilic dyes probing membrane microviscosity in biological membranes and in live cells.

Chmyrov V, Spielmann T, Hevekerl H, Widengren J.

Anal Chem. 2015 Jun 2;87(11):5690-7. doi: 10.1021/acs.analchem.5b00863. Epub 2015 May 14.

PMID:
25927252
25.

Determination of molecular stoichiometry without reference samples by analyzing fluorescence blinking with and without excitation synchronization.

Hevekerl H, Widengren J.

Methods Appl Fluoresc. 2015 Feb 26;3(2):025001. doi: 10.1088/2050-6120/3/2/025001.

PMID:
29148486
26.

SLC10A4 is a vesicular amine-associated transporter modulating dopamine homeostasis.

Larhammar M, Patra K, Blunder M, Emilsson L, Peuckert C, Arvidsson E, Rönnlund D, Preobraschenski J, Birgner C, Limbach C, Widengren J, Blom H, Jahn R, Wallén-Mackenzie Å, Kullander K.

Biol Psychiatry. 2015 Mar 15;77(6):526-36. doi: 10.1016/j.biopsych.2014.07.017. Epub 2014 Jul 24.

PMID:
25176177
27.

STED microscopy - towards broadened use and scope of applications.

Blom H, Widengren J.

Curr Opin Chem Biol. 2014 Jun;20:127-33. doi: 10.1016/j.cbpa.2014.06.004. Epub 2014 Jun 28. Review.

PMID:
24983537
28.

Scanning inverse fluorescence correlation spectroscopy.

Bergstrand J, Rönnlund D, Widengren J, Wennmalm S.

Opt Express. 2014 Jun 2;22(11):13073-90. doi: 10.1364/OE.22.013073.

PMID:
24921504
29.

Dark states in ionic oligothiophene bioprobes--evidence from fluorescence correlation spectroscopy and dynamic light scattering.

Hevekerl H, Wigenius J, Persson G, Inganäs O, Widengren J.

J Phys Chem B. 2014 Jun 5;118(22):5924-33. doi: 10.1021/jp501324e. Epub 2014 May 21.

PMID:
24807515
30.

Multicolor fluorescence nanoscopy by photobleaching: concept, verification, and its application to resolve selective storage of proteins in platelets.

Rönnlund D, Xu L, Perols A, Gad AK, Eriksson Karlström A, Auer G, Widengren J.

ACS Nano. 2014 May 27;8(5):4358-65. doi: 10.1021/nn406113m. Epub 2014 Apr 24.

PMID:
24730587
31.

Transient state imaging of live cells using single plane illumination and arbitrary duty cycle excitation pulse trains.

Mücksch J, Spielmann T, Sisamakis E, Widengren J.

J Biophotonics. 2015 May;8(5):392-400. doi: 10.1002/jbio.201400015. Epub 2014 Apr 7.

PMID:
24706633
32.

Chromatin in situ proximity (ChrISP): single-cell analysis of chromatin proximities at a high resolution.

Chen X, Shi C, Yammine S, Göndör A, Rönnlund D, Fernandez-Woodbridge A, Sumida N, Widengren J, Ohlsson R.

Biotechniques. 2014 Mar 1;56(3):117-8, 120-4. doi: 10.2144/000114145. eCollection 2014.

33.

Sequential pH-driven dimerization and stabilization of the N-terminal domain enables rapid spider silk formation.

Kronqvist N, Otikovs M, Chmyrov V, Chen G, Andersson M, Nordling K, Landreh M, Sarr M, Jörnvall H, Wennmalm S, Widengren J, Meng Q, Rising A, Otzen D, Knight SD, Jaudzems K, Johansson J.

Nat Commun. 2014;5:3254. doi: 10.1038/ncomms4254.

PMID:
24510122
34.

Oncogenes induce a vimentin filament collapse mediated by HDAC6 that is linked to cell stiffness.

Rathje LS, Nordgren N, Pettersson T, Rönnlund D, Widengren J, Aspenström P, Gad AK.

Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):1515-20. doi: 10.1073/pnas.1300238111. Epub 2014 Jan 13.

35.

Analysis of Rho GTPase-induced localization of nanoscale adhesions using fluorescence nanoscopy.

Gad AK, Rönnlund D, Widengren J, Aspenström P.

Methods Mol Biol. 2014;1120:339-57. doi: 10.1007/978-1-62703-791-4_22.

PMID:
24470036
36.

Transient state microscopy probes patterns of altered oxygen consumption in cancer cells.

Spielmann T, Xu L, Gad AK, Johansson S, Widengren J.

FEBS J. 2014 Mar;281(5):1317-32. doi: 10.1111/febs.12709. Epub 2014 Feb 3.

37.

Spatial distribution of DARPP-32 in dendritic spines.

Blom H, Rönnlund D, Scott L, Westin L, Widengren J, Aperia A, Brismar H.

PLoS One. 2013 Sep 10;8(9):e75155. doi: 10.1371/journal.pone.0075155. eCollection 2013.

38.

Spatial organization of proteins in metastasizing cells.

Rönnlund D, Gad AK, Blom H, Aspenström P, Widengren J.

Cytometry A. 2013 Sep;83(9):855-65. doi: 10.1002/cyto.a.22304. Epub 2013 May 8.

39.

dNTP-dependent conformational transitions in the fingers subdomain of Klentaq1 DNA polymerase: insights into the role of the "nucleotide-binding" state.

Rothwell PJ, Allen WJ, Sisamakis E, Kalinin S, Felekyan S, Widengren J, Waksman G, Seidel CA.

J Biol Chem. 2013 May 10;288(19):13575-91. doi: 10.1074/jbc.M112.432690. Epub 2013 Mar 22.

40.

Studying ion exchange in solution and at biological membranes by FCS.

Widengren J.

Methods Enzymol. 2013;519:231-52. doi: 10.1016/B978-0-12-405539-1.00008-7.

PMID:
23280113
41.

Fluorescence nanoscopy of platelets resolves platelet-state specific storage, release and uptake of proteins, opening up future diagnostic applications.

Rönnlund D, Yang Y, Blom H, Auer G, Widengren J.

Adv Healthc Mater. 2012 Nov;1(6):707-13. doi: 10.1002/adhm.201200172. Epub 2012 Sep 7.

PMID:
23184821
42.

Interferometry and fluorescence detection for simultaneous analysis of labeled and unlabeled nanoparticles in solution.

Wennmalm S, Widengren J.

J Am Chem Soc. 2012 Dec 5;134(48):19516-9. doi: 10.1021/ja308213q. Epub 2012 Nov 16.

PMID:
23157513
43.

Rho GTPases link cellular contractile force to the density and distribution of nanoscale adhesions.

Gad AK, Rönnlund D, Spaar A, Savchenko AA, Petranyi G, Blom H, Szekely L, Widengren J, Aspenström P.

FASEB J. 2012 Jun;26(6):2374-82. doi: 10.1096/fj.11-195800. Epub 2012 Feb 27.

PMID:
22371528
44.

LytA, major autolysin of Streptococcus pneumoniae, requires access to nascent peptidoglycan.

Mellroth P, Daniels R, Eberhardt A, Rönnlund D, Blom H, Widengren J, Normark S, Henriques-Normark B.

J Biol Chem. 2012 Mar 30;287(14):11018-29. doi: 10.1074/jbc.M111.318584. Epub 2012 Feb 9.

45.

Sequential closure of the cytoplasm and then the periplasm during cell division in Escherichia coli.

Skoog K, Söderström B, Widengren J, von Heijne G, Daley DO.

J Bacteriol. 2012 Feb;194(3):584-6. doi: 10.1128/JB.06091-11. Epub 2011 Nov 18.

46.

Förster resonance energy transfer beyond 10 nm: exploiting the triplet state kinetics of organic fluorophores.

Hevekerl H, Spielmann T, Chmyrov A, Widengren J.

J Phys Chem B. 2011 Nov 17;115(45):13360-70. doi: 10.1021/jp206770s. Epub 2011 Oct 19.

PMID:
21928769
47.

A modified FCCS procedure applied to Ly49A-MHC class I cis-interaction studies in cell membranes.

Strömqvist J, Johansson S, Xu L, Ohsugi Y, Andersson K, Muto H, Kinjo M, Höglund P, Widengren J.

Biophys J. 2011 Sep 7;101(5):1257-69. doi: 10.1016/j.bpj.2011.06.057.

48.

Nearest neighbor analysis of dopamine D1 receptors and Na(+)-K(+)-ATPases in dendritic spines dissected by STED microscopy.

Blom H, Rönnlund D, Scott L, Spicarova Z, Rantanen V, Widengren J, Aperia A, Brismar H.

Microsc Res Tech. 2012 Feb;75(2):220-8. doi: 10.1002/jemt.21046. Epub 2011 Aug 1.

PMID:
21809413
49.

Interactions between a luminescent conjugated oligoelectrolyte and insulin during early phases of amyloid formation.

Wigenius J, Persson G, Widengren J, Inganäs O.

Macromol Biosci. 2011 Aug 11;11(8):1120-7. doi: 10.1002/mabi.201100016. Epub 2011 May 9.

PMID:
21557477
50.

Spatial distribution of Na+-K+-ATPase in dendritic spines dissected by nanoscale superresolution STED microscopy.

Blom H, Rönnlund D, Scott L, Spicarova Z, Widengren J, Bondar A, Aperia A, Brismar H.

BMC Neurosci. 2011 Jan 27;12:16. doi: 10.1186/1471-2202-12-16.

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