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Items: 1 to 50 of 142

1.

Airway Gland Structure and Function.

Widdicombe JH, Wine JJ.

Physiol Rev. 2015 Oct;95(4):1241-319. doi: 10.1152/physrev.00039.2014. Review.

2.

Distribution and size of mucous glands in the ferret tracheobronchial tree.

Hajighasemi-Ossareh M, Borthwell RM, Lachowicz-Scroggins M, Stevens JE, Finkbeiner WE, Widdicombe JH.

Anat Rec (Hoboken). 2013 Nov;296(11):1768-74. doi: 10.1002/ar.22783. Epub 2013 Sep 17. Erratum in: Anat Rec (Hoboken). 2014 Jun;297(6):1163. Lachowicz-Scroggins, Marrah [added].

3.

A simple device to illustrate the Einthoven triangle.

Jin BE, Wulff H, Widdicombe JH, Zheng J, Bers DM, Puglisi JL.

Adv Physiol Educ. 2012 Dec;36(4):319-24. doi: 10.1152/advan.00029.2012.

4.

Differential effects of extracellular ATP on chloride transport in cortical collecting duct cells.

Rajagopal M, Kathpalia PP, Widdicombe JH, Pao AC.

Am J Physiol Renal Physiol. 2012 Aug 15;303(4):F483-91. doi: 10.1152/ajprenal.00062.2012. Epub 2012 May 30.

5.

Chloride secretion by cultures of pig tracheal gland cells.

Widdicombe JH, Borthwell RM, Hajighasemi-Ossareh M, Lachowicz-Scroggins ME, Finkbeiner WE, Stevens JE, Modlin S.

Am J Physiol Lung Cell Mol Physiol. 2012 May 15;302(10):L1098-106. doi: 10.1152/ajplung.00253.2011. Epub 2012 Feb 24.

6.

Cystic fibrosis and the relationship between mucin and chloride secretion by cultures of human airway gland mucous cells.

Finkbeiner WE, Zlock LT, Morikawa M, Lao AY, Dasari V, Widdicombe JH.

Am J Physiol Lung Cell Mol Physiol. 2011 Oct;301(4):L402-14. doi: 10.1152/ajplung.00210.2010. Epub 2011 Jul 1.

7.

Quantitative real-time PCR for rhinovirus, and its use in determining the relationship between TCID50 and the number of viral particles.

Sachs LA, Schnurr D, Yagi S, Lachowicz-Scroggins ME, Widdicombe JH.

J Virol Methods. 2011 Jan;171(1):212-8. doi: 10.1016/j.jviromet.2010.10.027. Epub 2010 Nov 9.

PMID:
21070809
8.

Transgenic animals may help resolve a sticky situation in cystic fibrosis.

Widdicombe JH.

J Clin Invest. 2010 Sep;120(9):3093-6. doi: 10.1172/JCI44235. Epub 2010 Aug 25.

9.

CFTR and calcium-activated chloride channels in primary cultures of human airway gland cells of serous or mucous phenotype.

Fischer H, Illek B, Sachs L, Finkbeiner WE, Widdicombe JH.

Am J Physiol Lung Cell Mol Physiol. 2010 Oct;299(4):L585-94. doi: 10.1152/ajplung.00421.2009. Epub 2010 Jul 30.

10.

Interleukin-13-induced mucous metaplasia increases susceptibility of human airway epithelium to rhinovirus infection.

Lachowicz-Scroggins ME, Boushey HA, Finkbeiner WE, Widdicombe JH.

Am J Respir Cell Mol Biol. 2010 Dec;43(6):652-61. doi: 10.1165/rcmb.2009-0244OC. Epub 2010 Jan 15.

11.

Cultures of human tracheal gland cells of mucous or serous phenotype.

Finkbeiner WE, Zlock LT, Mehdi I, Widdicombe JH.

In Vitro Cell Dev Biol Anim. 2010 May;46(5):450-6. doi: 10.1007/s11626-009-9262-x. Epub 2009 Dec 9.

12.

In vitro susceptibility to rhinovirus infection is greater for bronchial than for nasal airway epithelial cells in human subjects.

Lopez-Souza N, Favoreto S, Wong H, Ward T, Yagi S, Schnurr D, Finkbeiner WE, Dolganov GM, Widdicombe JH, Boushey HA, Avila PC.

J Allergy Clin Immunol. 2009 Jun;123(6):1384-90.e2. doi: 10.1016/j.jaci.2009.03.010. Epub 2009 May 9.

13.

Hormonal and purinergic stimulation of bicarbonate secretion in oviducts of rhesus monkey.

Rajagopal M, Fischer H, Widdicombe JH.

Am J Physiol Endocrinol Metab. 2008 Jul;295(1):E55-62. doi: 10.1152/ajpendo.00714.2007. Epub 2008 Apr 22.

14.

Basolateral Cl channels in primary airway epithelial cultures.

Fischer H, Illek B, Finkbeiner WE, Widdicombe JH.

Am J Physiol Lung Cell Mol Physiol. 2007 Jun;292(6):L1432-43. Epub 2007 Feb 23.

15.

Differentiated structure and function of primary cultures of monkey oviductal epithelium.

Rajagopal M, Tollner TL, Finkbeiner WE, Cherr GN, Widdicombe JH.

In Vitro Cell Dev Biol Anim. 2006 Sep-Oct;42(8-9):248-54.

PMID:
17163779
16.

Mechanisms of acid and base secretion by the airway epithelium.

Fischer H, Widdicombe JH.

J Membr Biol. 2006;211(3):139-50. Epub 2006 Nov 7. Review.

17.

Innate immune responses of human tracheal epithelium to Pseudomonas aeruginosa flagellin, TNF-alpha, and IL-1beta.

Tseng J, Do J, Widdicombe JH, Machen TE.

Am J Physiol Cell Physiol. 2006 Mar;290(3):C678-90. Epub 2005 Oct 26.

18.

Are Drosophila a useful model for understanding the toxicity of inhaled oxidative pollutants: a review.

Wilson M, Widdicombe JH, Gohil K, Burtis KC, Reznick AZ, Cross CE, Eiserich JP.

Inhal Toxicol. 2005 Dec 1;17(13):765-74.

PMID:
16195212
19.

Expansion of cultures of human tracheal epithelium with maintenance of differentiated structure and function.

Widdicombe JH, Sachs LA, Morrow JL, Finkbeiner WE.

Biotechniques. 2005 Aug;39(2):249-55.

20.

A novel extract SB-300 from the stem bark latex of Croton lechleri inhibits CFTR-mediated chloride secretion in human colonic epithelial cells.

Fischer H, Machen TE, Widdicombe JH, Carlson TJ, King SR, Chow JW, Illek B.

J Ethnopharmacol. 2004 Aug;93(2-3):351-7.

PMID:
15234776
21.

Endotoxin induces leukocyte transmigration and changes in permeability of the airway epithelium via protein-kinase C and extracellular regulated kinase activation.

Serikov VB, Choi H, Schmiel K, Skaggs C, Fleming NW, Wu R, Widdicombe JH.

J Endotoxin Res. 2004;10(1):55-65.

PMID:
15025824
22.

Secretion of lactoferrin and lysozyme by cultures of human airway epithelium.

Dubin RF, Robinson SK, Widdicombe JH.

Am J Physiol Lung Cell Mol Physiol. 2004 Apr;286(4):L750-5.

23.

Resistance of differentiated human airway epithelium to infection by rhinovirus.

Lopez-Souza N, Dolganov G, Dubin R, Sachs LA, Sassina L, Sporer H, Yagi S, Schnurr D, Boushey HA, Widdicombe JH.

Am J Physiol Lung Cell Mol Physiol. 2004 Feb;286(2):L373-81.

24.

Polarized cultures of human airway epithelium from nasal scrapings and bronchial brushings.

Lopez-Souza N, Avila PC, Widdicombe JH.

In Vitro Cell Dev Biol Anim. 2003 Jul-Aug;39(7):266-9.

PMID:
14531727
25.

Effects of media on differentiation of cultured human tracheal epithelium.

Sachs LA, Finkbeiner WE, Widdicombe JH.

In Vitro Cell Dev Biol Anim. 2003 Jan-Feb;39(1-2):56-62.

PMID:
12892528
26.

Effects of growth surface on differentiation of cultures of human tracheal epithelium.

Widdicombe JH, Sachs LA, Finkbeiner WE.

In Vitro Cell Dev Biol Anim. 2003 Jan-Feb;39(1-2):51-5.

PMID:
12892527
27.

Activation of extracellular regulated kinases is required for the increase in airway epithelial permeability during leukocyte transmigration.

Serikov VB, Choi H, Chmiel KJ, Wu R, Widdicombe JH.

Am J Respir Cell Mol Biol. 2004 Mar;30(3):261-70. Epub 2003 Jul 3.

PMID:
12842851
28.

Measurement of nasal potential difference in mild asthmatics.

Chung NC, Illek B, Widdicombe JH, Fischer H.

Chest. 2003 May;123(5):1467-71.

PMID:
12740262
29.

Regulation of the depth and composition of airway surface liquid.

Widdicombe JH.

J Anat. 2002 Oct;201(4):313-8. Review.

30.

Distribution and numbers of mucous glands in the horse trachea.

Widdicombe JH, Pecson IS.

Equine Vet J. 2002 Sep;34(6):630-3.

PMID:
12358006
31.

Volume of airway surface liquid in health and disease.

Widdicombe JH.

Am J Respir Crit Care Med. 2002 Jun 1;165(11):1566. No abstract available.

PMID:
12045135
32.

Estimate of the subepithelial hydrostatic pressure that drives inflammatory transudate into the airway lumen.

Serikov VB, Jang YJ, Widdicombe JH.

J Appl Physiol (1985). 2002 Apr;92(4):1702-8.

33.

Acid secretion and proton conductance in human airway epithelium.

Fischer H, Widdicombe JH, Illek B.

Am J Physiol Cell Physiol. 2002 Apr;282(4):C736-43.

34.

Altered NaCl concentration of airway surface liquid in cystic fibrosis.

Widdicombe JH.

Pflugers Arch. 2001;443 Suppl 1:S8-10. Epub 2001 Jun 28.

PMID:
11845295
35.

Alveolar epithelial type I cells contain transport proteins and transport sodium, supporting an active role for type I cells in regulation of lung liquid homeostasis.

Johnson MD, Widdicombe JH, Allen L, Barbry P, Dobbs LG.

Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):1966-71. Epub 2002 Feb 12.

36.

Altered NaCl Concentration of Airway Surface Liquid in Cystic Fibrosis.

Widdicombe JH.

News Physiol Sci. 1999 Jun;14:126-127. No abstract available.

PMID:
11390837
37.

Distribution of tracheal and laryngeal mucous glands in some rodents and the rabbit.

Widdicombe JH, Chen LL, Sporer H, Choi HK, Pecson IS, Bastacky SJ.

J Anat. 2001 Feb;198(Pt 2):207-21.

38.

A comparative study of mammalian tracheal mucous glands.

Choi HK, Finkbeiner WE, Widdicombe JH.

J Anat. 2000 Oct;197 Pt 3:361-72.

39.

Yet another role for the cystic fibrosis transmembrane conductance regulator.

Widdicombe JH.

Am J Respir Cell Mol Biol. 2000 Jan;22(1):11-4. Review. No abstract available.

PMID:
10615060
40.

Restoration of cyclic adenosine monophosphate-stimulated chloride channel activity in human cystic fibrosis tracheobronchial submucosal gland cells by adenovirus-mediated and cationic lipid-mediated gene transfer.

Jiang C, Finkbeiner WE, Widdicombe JH, Fang SL, Wang KX, Nietupski JB, Hehir KM, Cheng SH.

Am J Respir Cell Mol Biol. 1999 Jun;20(6):1107-15.

PMID:
10340929
41.

cAMP-dependent absorption of chloride across airway epithelium.

Uyekubo SN, Fischer H, Maminishkis A, Illek B, Miller SS, Widdicombe JH.

Am J Physiol. 1998 Dec;275(6 Pt 1):L1219-27.

PMID:
9843860
42.

Pseudomonas aeruginosa induces changes in fluid transport across airway surface epithelia.

Evans DJ, Matsumoto PS, Widdicombe JH, Li-Yun C, Maminishkis AA, Miller SS.

Am J Physiol. 1998 Nov;275(5 Pt 1):C1284-90.

PMID:
9814977
43.

Loss of CFTR chloride channels alters salt absorption by cystic fibrosis airway epithelia in vitro.

Zabner J, Smith JJ, Karp PH, Widdicombe JH, Welsh MJ.

Mol Cell. 1998 Sep;2(3):397-403.

44.

Efficient expression of CFTR function with adeno-associated virus vectors that carry shortened CFTR genes.

Zhang L, Wang D, Fischer H, Fan PD, Widdicombe JH, Kan YW, Dong JY.

Proc Natl Acad Sci U S A. 1998 Aug 18;95(17):10158-63.

45.

Evidence that Calu-3 human airway cells secrete bicarbonate.

Lee MC, Penland CM, Widdicombe JH, Wine JJ.

Am J Physiol. 1998 Mar;274(3 Pt 1):L450-3.

PMID:
9530182
46.

Regulation of the depth of surface liquid in bovine trachea.

Wu DX, Lee CY, Uyekubo SN, Choi HK, Bastacky SJ, Widdicombe JH.

Am J Physiol. 1998 Mar;274(3 Pt 1):L388-95.

PMID:
9530174
47.

Regulation of depth and composition of airway surface liquid.

Widdicombe JH, Bastacky SJ, Wu DX, Lee CY.

Eur Respir J. 1997 Dec;10(12):2892-7. Review.

48.

Cultured lung epithelium: A cellular model for lung preservation.

Lee CY, Matsumoto-Pon J, Widdicombe JH.

Cryobiology. 1997 Nov;35(3):209-18.

PMID:
9367609
49.
50.

Fluid transport across cultures of human tracheal glands is altered in cystic fibrosis.

Jiang C, Finkbeiner WE, Widdicombe JH, Miller SS.

J Physiol. 1997 Jun 15;501 ( Pt 3):637-47.

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