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Items: 1 to 50 of 292

1.

Precision delivery of RAS-inhibiting siRNA to KRAS driven cancer via peptide-based nanoparticles.

Strand MS, Krasnick BA, Pan H, Zhang X, Bi Y, Brooks C, Wetzel C, Sankpal N, Fleming T, Goedegebuure SP, DeNardo DG, Gillanders WE, Hawkins WG, Wickline SA, Fields RC.

Oncotarget. 2019 Jul 30;10(46):4761-4775. doi: 10.18632/oncotarget.27109. eCollection 2019 Jul 30.

2.

Low dose chloroquine decreases insulin resistance in human metabolic syndrome but does not reduce carotid intima-media thickness.

McGill JB, Johnson M, Hurst S, Cade WT, Yarasheski KE, Ostlund RE, Schechtman KB, Razani B, Kastan MB, McClain DA, de Las Fuentes L, Davila-Roman VG, Ory DS, Wickline SA, Semenkovich CF.

Diabetol Metab Syndr. 2019 Jul 29;11:61. doi: 10.1186/s13098-019-0456-4. eCollection 2019.

3.

A murine neonatal model of necrotizing enterocolitis caused by anemia and red blood cell transfusions.

MohanKumar K, Namachivayam K, Song T, Jake Cha B, Slate A, Hendrickson JE, Pan H, Wickline SA, Oh JY, Patel RP, He L, Torres BA, Maheshwari A.

Nat Commun. 2019 Aug 2;10(1):3494. doi: 10.1038/s41467-019-11199-5.

4.

Applications of RNA interference in the treatment of arthritis.

Rai MF, Pan H, Yan H, Sandell LJ, Pham CTN, Wickline SA.

Transl Res. 2019 Jul 10. pii: S1931-5244(19)30135-5. doi: 10.1016/j.trsl.2019.07.002. [Epub ahead of print] Review.

PMID:
31351032
5.

Resolution of Murine Toxic Hepatic Injury Quantified With Ultrasound Entropy Metrics.

Marsh JN, Korenblat KM, Liu TC, McCarthy JE, Wickline SA.

Ultrasound Med Biol. 2019 Oct;45(10):2777-2786. doi: 10.1016/j.ultrasmedbio.2019.06.412. Epub 2019 Jul 15.

PMID:
31320149
6.

Division of labor in honey bees is associated with transcriptional regulatory plasticity in the brain.

Hamilton AR, Traniello IM, Ray AM, Caldwell AS, Wickline SA, Robinson GE.

J Exp Biol. 2019 Jul 16;222(Pt 14). pii: jeb200196. doi: 10.1242/jeb.200196.

PMID:
31138635
7.

p5RHH nanoparticle-mediated delivery of AXL siRNA inhibits metastasis of ovarian and uterine cancer cells in mouse xenografts.

Mills KA, Quinn JM, Roach ST, Palisoul M, Nguyen M, Noia H, Guo L, Fazal J, Mutch DG, Wickline SA, Pan H, Fuh KC.

Sci Rep. 2019 Mar 18;9(1):4762. doi: 10.1038/s41598-019-41122-3.

8.

Development of a peptide-siRNA nanocomplex targeting NF- κB for efficient cartilage delivery.

Yan H, Duan X, Pan H, Akk A, Sandell LJ, Wickline SA, Rai MF, Pham CTN.

Sci Rep. 2019 Jan 24;9(1):442. doi: 10.1038/s41598-018-37018-3.

9.

Antithrombin Perfluorocarbon Nanoparticles Improve Renal Allograft Function in a Murine Deceased Criteria Donor Model.

Vemuri C, Upadhya GA, Arif B, Jia J, Lin Y, Gaut JP, Fazal J, Pan H, Wickline SA, Chapman WC.

Transplant Direct. 2018 Aug 21;4(9):e384. doi: 10.1097/TXD.0000000000000817. eCollection 2018 Sep.

10.

Anti-JNK2 peptide-siRNA nanostructures improve plaque endothelium and reduce thrombotic risk in atherosclerotic mice.

Pan H, Palekar RU, Hou KK, Bacon J, Yan H, Springer LE, Akk A, Yang L, Miller MJ, Pham CT, Schlesinger PH, Wickline SA.

Int J Nanomedicine. 2018 Sep 6;13:5187-5205. doi: 10.2147/IJN.S168556. eCollection 2018.

11.

Requisite endothelial reactivation and effective siRNA nanoparticle targeting of Etv2/Er71 in tumor angiogenesis.

Kabir AU, Lee TJ, Pan H, Berry JC, Krchma K, Wu J, Liu F, Kang HK, Hinman K, Yang L, Hamilton S, Zhou Q, Veis DJ, Mecham RP, Wickline SA, Miller MJ, Choi K.

JCI Insight. 2018 Apr 19;3(8). pii: 97349. doi: 10.1172/jci.insight.97349. eCollection 2018 Apr 19.

12.

Quantification of vascular damage in acute kidney injury with fluorine magnetic resonance imaging and spectroscopy.

Moore JK, Chen J, Pan H, Gaut JP, Jain S, Wickline SA.

Magn Reson Med. 2018 Jun;79(6):3144-3153. doi: 10.1002/mrm.26985. Epub 2017 Nov 16.

13.

Attenuated Superoxide Dismutase 2 Activity Induces Atherosclerotic Plaque Instability During Aging in Hyperlipidemic Mice.

Vendrov AE, Stevenson MD, Alahari S, Pan H, Wickline SA, Madamanchi NR, Runge MS.

J Am Heart Assoc. 2017 Oct 27;6(11). pii: e006775. doi: 10.1161/JAHA.117.006775.

14.

Efficacy of RNA interference knockdown using aerosolized short interfering RNAs bound to nanoparticles in three diverse aphid species.

Thairu MW, Skidmore IH, Bansal R, Nováková E, Hansen TE, Li-Byarlay H, Wickline SA, Hansen AK.

Insect Mol Biol. 2017 Jun;26(3):356-368. doi: 10.1111/imb.12301. Epub 2017 Mar 17.

PMID:
28314050
15.

NADPH oxidase 4 regulates vascular inflammation in aging and atherosclerosis.

Lozhkin A, Vendrov AE, Pan H, Wickline SA, Madamanchi NR, Runge MS.

J Mol Cell Cardiol. 2017 Jan;102:10-21. doi: 10.1016/j.yjmcc.2016.12.004. Epub 2016 Dec 14.

16.

Antithrombin nanoparticles inhibit stent thrombosis in ex vivo static and flow models.

Palekar RU, Vemuri C, Marsh JN, Arif B, Wickline SA.

J Vasc Surg. 2016 Nov;64(5):1459-1467. doi: 10.1016/j.jvs.2015.08.086. Epub 2015 Oct 17.

17.

Suppression of NF-κB activity via nanoparticle-based siRNA delivery alters early cartilage responses to injury.

Yan H, Duan X, Pan H, Holguin N, Rai MF, Akk A, Springer LE, Wickline SA, Sandell LJ, Pham CT.

Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6199-E6208. Epub 2016 Sep 28. Erratum in: Proc Natl Acad Sci U S A. 2017 May 9;114(19):E3871.

18.

Recent Advances in 19Fluorine Magnetic Resonance Imaging with Perfluorocarbon Emulsions.

Schmieder AH, Caruthers SD, Keupp J, Wickline SA, Lanza GM.

Engineering (Beijing). 2015 Dec;1(4):475-489. Epub 2016 Mar 16.

19.

Entropy vs. Energy Waveform Processing: A Comparison Based on the Heat Equation.

Hughes MS, McCarthy JE, Bruillard PJ, Marsh JN, Wickline SA.

Entropy (Basel). 2015 Jun;17(6):3518-3551. Epub 2015 May 25.

20.

Inhibition of Thrombin With PPACK-Nanoparticles Restores Disrupted Endothelial Barriers and Attenuates Thrombotic Risk in Experimental Atherosclerosis.

Palekar RU, Jallouk AP, Myerson JW, Pan H, Wickline SA.

Arterioscler Thromb Vasc Biol. 2016 Mar;36(3):446-55. doi: 10.1161/ATVBAHA.115.306697. Epub 2016 Jan 14.

21.

Dual-therapy with αvβ3-targeted Sn2 lipase-labile fumagillin-prodrug nanoparticles and zoledronic acid in the Vx2 rabbit tumor model.

Esser AK, Schmieder AH, Ross MH, Xiang J, Su X, Cui G, Zhang H, Yang X, Allen JS, Williams T, Wickline SA, Pan D, Lanza GM, Weilbaecher KN.

Nanomedicine. 2016 Jan;12(1):201-11. doi: 10.1016/j.nano.2015.10.003. Epub 2015 Oct 27.

22.

Contact-facilitated drug delivery with Sn2 lipase labile prodrugs optimize targeted lipid nanoparticle drug delivery.

Pan D, Pham CT, Weilbaecher KN, Tomasson MH, Wickline SA, Lanza GM.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2016 Jan-Feb;8(1):85-106. doi: 10.1002/wnan.1355. Epub 2015 Aug 21. Review.

23.

Peptide-siRNA nanotherapeutics in arthritis.

Pham CT, Pan H, Wickline SA.

Oncotarget. 2015 Jun 20;6(17):14731-2. No abstract available.

24.

Delivery of a Protease-Activated Cytolytic Peptide Prodrug by Perfluorocarbon Nanoparticles.

Jallouk AP, Palekar RU, Marsh JN, Pan H, Pham CT, Schlesinger PH, Wickline SA.

Bioconjug Chem. 2015 Aug 19;26(8):1640-50. doi: 10.1021/acs.bioconjchem.5b00246. Epub 2015 Jul 2.

25.

Molecular imaging of atherosclerosis with nanoparticle-based fluorinated MRI contrast agents.

Palekar RU, Jallouk AP, Lanza GM, Pan H, Wickline SA.

Nanomedicine (Lond). 2015;10(11):1817-32. doi: 10.2217/nnm.15.26. Review.

26.

A role for peptides in overcoming endosomal entrapment in siRNA delivery - A focus on melittin.

Hou KK, Pan H, Schlesinger PH, Wickline SA.

Biotechnol Adv. 2015 Nov 1;33(6 Pt 1):931-40. doi: 10.1016/j.biotechadv.2015.05.005. Epub 2015 May 27. Review.

27.

Quantifying progression and regression of thrombotic risk in experimental atherosclerosis.

Palekar RU, Jallouk AP, Goette MJ, Chen J, Myerson JW, Allen JS, Akk A, Yang L, Tu Y, Miller MJ, Pham CT, Wickline SA, Pan H.

FASEB J. 2015 Jul;29(7):3100-9. doi: 10.1096/fj.14-269084. Epub 2015 Apr 9.

28.

Modifications of natural peptides for nanoparticle and drug design.

Jallouk AP, Palekar RU, Pan H, Schlesinger PH, Wickline SA.

Adv Protein Chem Struct Biol. 2015;98:57-91. doi: 10.1016/bs.apcsb.2014.12.001. Epub 2015 Mar 12. Review.

29.

Synergy between surface and core entrapped metals in a mixed manganese-gadolinium nanocolloid affords safer MR imaging of sparse biomarkers.

Wang K, Pan D, Schmieder AH, Senpan A, Hourcade DE, Pham CT, Mitchell LM, Caruthers SD, Cui G, Wickline SA, Shen B, Lanza GM.

Nanomedicine. 2015 Apr;11(3):601-9. doi: 10.1016/j.nano.2014.12.009. Epub 2015 Jan 31.

30.

Antithrombin nanoparticles improve kidney reperfusion and protect kidney function after ischemia-reperfusion injury.

Chen J, Vemuri C, Palekar RU, Gaut JP, Goette M, Hu L, Cui G, Zhang H, Wickline SA.

Am J Physiol Renal Physiol. 2015 Apr 1;308(7):F765-73. doi: 10.1152/ajprenal.00457.2014. Epub 2015 Jan 28.

31.

Additional results for "joint entropy of continuously differentiable ultrasonic waveforms" [J. Acoust. Soc. Am. 133(1), 283-300 (2013)].

Hughes MS, Marsh JN, Wickline SA, McCarthy JE.

J Acoust Soc Am. 2015 Jan;137(1):501. doi: 10.1121/1.4904531.

32.

A strategy for combating melanoma with oncogenic c-Myc inhibitors and targeted nanotherapy.

Pan D, Kim B, Hu G, Gupta DS, Senpan A, Yang X, Schmieder A, Swain C, Wickline SA, Tomasson MH, Lanza GM.

Nanomedicine (Lond). 2015 Jan;10(2):241-51. doi: 10.2217/nnm.14.101.

33.

Improved quantitative (19) F MR molecular imaging with flip angle calibration and B1 -mapping compensation.

Goette MJ, Lanza GM, Caruthers SD, Wickline SA.

J Magn Reson Imaging. 2015 Aug;42(2):488-94. doi: 10.1002/jmri.24812. Epub 2014 Nov 25.

34.

Balanced UTE-SSFP for 19F MR imaging of complex spectra.

Goette MJ, Keupp J, Rahmer J, Lanza GM, Wickline SA, Caruthers SD.

Magn Reson Med. 2015 Aug;74(2):537-43. doi: 10.1002/mrm.25437. Epub 2014 Aug 27.

35.

Peptide-siRNA nanocomplexes targeting NF-κB subunit p65 suppress nascent experimental arthritis.

Zhou HF, Yan H, Pan H, Hou KK, Akk A, Springer LE, Hu Y, Allen JS, Wickline SA, Pham CT.

J Clin Invest. 2014 Oct;124(10):4363-74. doi: 10.1172/JCI75673. Epub 2014 Aug 26.

36.

Angiogenesis and airway reactivity in asthmatic Brown Norway rats.

Wagner EM, Jenkins J, Schmieder A, Eldridge L, Zhang Q, Moldobaeva A, Zhang H, Allen JS, Yang X, Mitzner W, Keupp J, Caruthers SD, Wickline SA, Lanza GM.

Angiogenesis. 2015 Jan;18(1):1-11. doi: 10.1007/s10456-014-9441-6. Epub 2014 Aug 23.

37.

A review of exosome separation techniques and characterization of B16-F10 mouse melanoma exosomes with AF4-UV-MALS-DLS-TEM.

Petersen KE, Manangon E, Hood JL, Wickline SA, Fernandez DP, Johnson WP, Gale BK.

Anal Bioanal Chem. 2014 Dec;406(30):7855-66. doi: 10.1007/s00216-014-8040-0. Epub 2014 Aug 2. Review.

38.

Magnetic resonance imaging of melanoma exosomes in lymph nodes.

Hu L, Wickline SA, Hood JL.

Magn Reson Med. 2015 Jul;74(1):266-271. doi: 10.1002/mrm.25376. Epub 2014 Jul 22.

39.

Fumagillin prodrug nanotherapy suppresses macrophage inflammatory response via endothelial nitric oxide.

Zhou HF, Yan H, Hu Y, Springer LE, Yang X, Wickline SA, Pan D, Lanza GM, Pham CT.

ACS Nano. 2014 Jul 22;8(7):7305-17. doi: 10.1021/nn502372n. Epub 2014 Jun 24.

40.

MR cholangiography demonstrates unsuspected rapid biliary clearance of nanoparticles in rodents: implications for clinical translation.

Bulte JW, Schmieder AH, Keupp J, Caruthers SD, Wickline SA, Lanza GM.

Nanomedicine. 2014 Oct;10(7):1385-8. doi: 10.1016/j.nano.2014.05.001. Epub 2014 May 14.

41.

Nanoparticle incorporation of melittin reduces sperm and vaginal epithelium cytotoxicity.

Jallouk AP, Moley KH, Omurtag K, Hu G, Lanza GM, Wickline SA, Hood JL.

PLoS One. 2014 Apr 18;9(4):e95411. doi: 10.1371/journal.pone.0095411. eCollection 2014.

42.

Anti-angiogenesis therapy in the Vx2 rabbit cancer model with a lipase-cleavable Sn 2 taxane phospholipid prodrug using α(v)β₃-targeted theranostic nanoparticles.

Pan D, Schmieder AH, Wang K, Yang X, Senpan A, Cui G, Killgore K, Kim B, Allen JS, Zhang H, Caruthers SD, Shen B, Wickline SA, Lanza GM.

Theranostics. 2014 Mar 11;4(6):565-78. doi: 10.7150/thno.7581. eCollection 2014.

43.

Bicuspid Pulmonic Valve and Pulmonary Artery Aneurysm.

Jamis-Dow CA, Barbier GH, Watkins MP, Lanza GM, Caruthers SD, Wickline SA.

Cardiol Res. 2014 Apr;5(2):83-84.

44.

Rapamycin nanoparticles target defective autophagy in muscular dystrophy to enhance both strength and cardiac function.

Bibee KP, Cheng YJ, Ching JK, Marsh JN, Li AJ, Keeling RM, Connolly AM, Golumbek PT, Myerson JW, Hu G, Chen J, Shannon WD, Lanza GM, Weihl CC, Wickline SA.

FASEB J. 2014 May;28(5):2047-61. doi: 10.1096/fj.13-237388. Epub 2014 Feb 5.

45.

Multicolor computed tomographic molecular imaging with noncrystalline high-metal-density nanobeacons.

Pan D, Schirra CO, Wickline SA, Lanza GM.

Contrast Media Mol Imaging. 2014 Jan-Feb;9(1):13-25. doi: 10.1002/cmmi.1571. Review.

46.

Maximizing exosome colloidal stability following electroporation.

Hood JL, Scott MJ, Wickline SA.

Anal Biochem. 2014 Mar 1;448:41-9. doi: 10.1016/j.ab.2013.12.001. Epub 2013 Dec 9.

47.

Perfluorocarbon nanoparticles for physiological and molecular imaging and therapy.

Chen J, Pan H, Lanza GM, Wickline SA.

Adv Chronic Kidney Dis. 2013 Nov;20(6):466-78. doi: 10.1053/j.ackd.2013.08.004. Review.

48.

Thrombin-targeted liposomes establish a sustained localized anticlotting barrier against acute thrombosis.

Palekar RU, Myerson JW, Schlesinger PH, Sadler JE, Pan H, Wickline SA.

Mol Pharm. 2013 Nov 4;10(11):4168-75. doi: 10.1021/mp400210q. Epub 2013 Oct 10.

49.

Mechanisms of nanoparticle-mediated siRNA transfection by melittin-derived peptides.

Hou KK, Pan H, Ratner L, Schlesinger PH, Wickline SA.

ACS Nano. 2013 Oct 22;7(10):8605-15. doi: 10.1021/nn403311c. Epub 2013 Sep 26.

50.

Assessing intrarenal nonperfusion and vascular leakage in acute kidney injury with multinuclear (1) H/(19) F MRI and perfluorocarbon nanoparticles.

Hu L, Chen J, Yang X, Senpan A, Allen JS, Yanaba N, Caruthers SD, Lanza GM, Hammerman MR, Wickline SA.

Magn Reson Med. 2014 Jun;71(6):2186-96. doi: 10.1002/mrm.24851. Epub 2013 Aug 8.

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