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Items: 35

1.

Pharmacological Characterization of a Novel Beta 3 Adrenergic Agonist, Vibegron: Evaluation of Antimuscarinic Receptor Selectivity for Combination Therapy for Overactive Bladder.

Di Salvo J, Nagabukuro H, Wickham LA, Abbadie C, DeMartino JA, Fitzmaurice A, Gichuru L, Kulick A, Donnelly MJ, Jochnowitz N, Hurley AL, Pereira A, Sanfiz A, Veronin G, Villa K, Woods J, Zamlynny B, Zycband E, Salituro GM, Frenkl T, Weber AE, Edmondson SD, Struthers M.

J Pharmacol Exp Ther. 2017 Feb;360(2):346-355. doi: 10.1124/jpet.116.237313. Epub 2016 Dec 13.

PMID:
27965369
2.

Differential anti-thrombotic benefit and bleeding risk profiles of antagonists of protease-activated receptor 1 and 4 in Cynomolgus Macaques.

Wickham LA, Sitko G, Stranieri-Michener M, Handt L, Basso A, Fried S, Chu L, Maderia M, Owens K, Castriota G, Chen Z, Metzger JM, Imbriglio J, Wang X, Cai TQ.

Thromb Res. 2016 Sep;145:133-9. doi: 10.1016/j.thromres.2016.06.007. Epub 2016 Jun 11.

PMID:
27318768
3.

Platelet transfusion reverses bleeding evoked by triple anti-platelet therapy including vorapaxar, a novel platelet thrombin receptor antagonist.

Cai TQ, Wickham LA, Sitko G, Michener MS, Raubertas R, Handt L, Chintala M, Seiffert D, Forrest M.

Eur J Pharmacol. 2015 Jul 5;758:107-14. doi: 10.1016/j.ejphar.2015.03.073. Epub 2015 Apr 7.

PMID:
25857224
4.

Plasma lipid profiling across species for the identification of optimal animal models of human dyslipidemia.

Yin W, Carballo-Jane E, McLaren DG, Mendoza VH, Gagen K, Geoghagen NS, McNamara LA, Gorski JN, Eiermann GJ, Petrov A, Wolff M, Tong X, Wilsie LC, Akiyama TE, Chen J, Thankappan A, Xue J, Ping X, Andrews G, Wickham LA, Gai CL, Trinh T, Kulick AA, Donnelly MJ, Voronin GO, Rosa R, Cumiskey AM, Bekkari K, Mitnaul LJ, Puig O, Chen F, Raubertas R, Wong PH, Hansen BC, Koblan KS, Roddy TP, Hubbard BK, Strack AM.

J Lipid Res. 2012 Jan;53(1):51-65. doi: 10.1194/jlr.M019927. Epub 2011 Oct 23.

5.

Transurethral bladder catheterization of male rhesus macaques: a refinement of approach.

Wickham LA, Kulick AA, Gichuru L, Donnelly MJ, Gai CL, Johnson CV, Hickey EJ, Nagabukuro H.

J Med Primatol. 2011 Oct;40(5):342-50. doi: 10.1111/j.1600-0684.2011.00494.x.

PMID:
21950722
6.

Comparative analysis of the effects of antimuscarinic agents on bladder functions in both nonhuman primates and rodents.

Nagabukuro H, Villa KL, Wickham LA, Kulick AA, Gichuru L, Donnelly MJ, Voronin GO, Pereira T, Tong X, Nichols A, Alves SE, O'Neill GP, Johnson CV, Hickey EJ.

J Pharmacol Exp Ther. 2011 Jul;338(1):220-7. doi: 10.1124/jpet.111.179747. Epub 2011 Apr 1.

PMID:
21459965
7.

Use of a rigid endoscope to teach urethral catheterization of the female dog.

Voronin GO, Porter WP, Wickham LA, Gai CL, Rasa CG, West SH, Shah K.

Lab Anim (NY). 2009 Aug;38(8):271-4. doi: 10.1038/laban0809-271.

PMID:
19626020
8.

Sphingosine-1-phosphate agonists increase macrophage homing, lymphocyte contacts, and endothelial junctional complex formation in murine lymph nodes.

Singer II, Tian M, Wickham LA, Lin J, Matheravidathu SS, Forrest MJ, Mandala S, Quackenbush EJ.

J Immunol. 2005 Dec 1;175(11):7151-61.

9.

Discovery of potent 3,5-diphenyl-1,2,4-oxadiazole sphingosine-1-phosphate-1 (S1P1) receptor agonists with exceptional selectivity against S1P2 and S1P3.

Li Z, Chen W, Hale JJ, Lynch CL, Mills SG, Hajdu R, Keohane CA, Rosenbach MJ, Milligan JA, Shei GJ, Chrebet G, Parent SA, Bergstrom J, Card D, Forrest M, Quackenbush EJ, Wickham LA, Vargas H, Evans RM, Rosen H, Mandala S.

J Med Chem. 2005 Oct 6;48(20):6169-73.

PMID:
16190743
10.

Androgen control of gene expression in the rabbit meibomian gland.

Steagall RJ, Yamagami H, Wickham LA, Sullivan DA.

Adv Exp Med Biol. 2002;506(Pt A):465-76. No abstract available.

PMID:
12613947
11.

Androgen influence on the meibomian gland.

Sullivan DA, Sullivan BD, Ullman MD, Rocha EM, Krenzer KL, Cermak JM, Toda I, Doane MG, Evans JE, Wickham LA.

Invest Ophthalmol Vis Sci. 2000 Nov;41(12):3732-42.

PMID:
11053270
12.

Identification of androgen, estrogen and progesterone receptor mRNAs in the eye.

Wickham LA, Gao J, Toda I, Rocha EM, Ono M, Sullivan DA.

Acta Ophthalmol Scand. 2000 Apr;78(2):146-53.

13.
14.

Identification of androgen receptor protein and 5alpha-reductase mRNA in human ocular tissues.

Rocha EM, Wickham LA, da Silveira LA, Krenzer KL, Yu FS, Toda I, Sullivan BD, Sullivan DA.

Br J Ophthalmol. 2000 Jan;84(1):76-84.

15.

Impact of gender on exocrine gland inflammation in mouse models of Sjögren's syndrome.

Toda I, Sullivan BD, Rocha EM, Da Silveira LA, Wickham LA, Sullivan DA.

Exp Eye Res. 1999 Oct;69(4):355-66.

PMID:
10504269
16.

Androgens and dry eye in Sjögren's syndrome.

Sullivan DA, Wickham LA, Rocha EM, Krenzer KL, Sullivan BD, Steagall R, Cermak JM, Dana MR, Ullman MD, Sato EH, Gao J, Rocha FJ, Ono M, Silveira LA, Lambert RW, Kelleher RS, Tolls DB, Toda I.

Ann N Y Acad Sci. 1999 Jun 22;876:312-24. Review.

PMID:
10415627
17.

Presence and testosterone influence on the levels of anti- and pro-inflammatory cytokines in lacrimal tissues of a mouse model of Sjögren's syndrome.

Rocha EM, Wickham LA, Huang Z, Toda I, Gao J, da Silveira LA, Sullivan DA.

Adv Exp Med Biol. 1998;438:485-91. No abstract available.

PMID:
9634925
18.

Gender- and androgen-related impact on the expression of proto-oncogenes and apoptotic factors in lacrimal and salivary glands of mouse models of Sjögren's syndrome.

Toda I, Wickham LA, Rocha EM, da Silveira LA, Sullivan DA.

Adv Exp Med Biol. 1998;438:447-52. No abstract available.

PMID:
9634920
19.

Androgen regulation of the meibomian gland.

Sullivan DA, Rocha EM, Ullman MD, Krenzer KL, Gao J, Toda I, Dana MR, Bazzinotti D, da Silveira LA, Wickham LA.

Adv Exp Med Biol. 1998;438:327-31. No abstract available.

PMID:
9634904
20.

Identification and hormonal control of sex steroid receptors in the eye.

Wickham LA, Rocha EM, Gao J, Krenzer KL, da Silveira LA, Toda I, Sullivan DA.

Adv Exp Med Biol. 1998;438:95-100. No abstract available.

PMID:
9634870
21.

Influence of gender, sex steroid hormones, and the hypothalamic-pituitary axis on the structure and function of the lacrimal gland.

Sullivan DA, Wickham LA, Rocha EM, Kelleher RS, da Silveira LA, Toda I.

Adv Exp Med Biol. 1998;438:11-42. Review. No abstract available.

PMID:
9634860
22.

The local public health agency review process in Oregon, 1985-1997.

Wickham LA.

J Public Health Manag Pract. 1998 Jul;4(4):10-3. Review. No abstract available.

PMID:
10186749
23.
24.

Effect of sialodacryoadenitis virus exposure on acinar epithelial cells from the rat lacrimal gland.

Wickham LA, Huang Z, Lambert RW, Sullivan DA.

Ocul Immunol Inflamm. 1997 Sep;5(3):181-95.

PMID:
9326763
25.

Analysis of cytomegalovirus infection and replication in acinar epithelial cells of the rat lacrimal gland.

Huang Z, Lambert RW, Wickham LA, Sullivan DA.

Invest Ophthalmol Vis Sci. 1996 May;37(6):1174-86.

PMID:
8631632
26.

Identification and endocrine control of sex steroid binding sites in the lacrimal gland.

Sullivan DA, Edwards JA, Wickham LA, Pena JD, Gao J, Ono M, Kelleher RS.

Curr Eye Res. 1996 Mar;15(3):279-91.

PMID:
8654108
27.

Androgen control of secretory component mRNA levels in the rat lacrimal gland.

Gao J, Lambert RW, Wickham LA, Banting G, Sullivan DA.

J Steroid Biochem Mol Biol. 1995 Mar;52(3):239-49.

PMID:
7696145
28.

Neural, endocrine and immune regulation of secretory component production by lacrimal gland acinar cells.

Lambert RW, Gao J, Kelleher RS, Wickham LA, Sullivan DA.

Adv Exp Med Biol. 1995;371A:221-4. No abstract available.

PMID:
8525911
29.

Herpes- and corona-virus infection of rat lacrimal acinar cells.

Wickham LA, Huang Z, Lambert RW, Sullivan DA.

Adv Exp Med Biol. 1995;371B:999-1002. No abstract available.

PMID:
7502945
30.

Neuroendocrinimmune modulation of secretory component production by rat lacrimal, salivary, and intestinal epithelial cells.

Lambert RW, Kelleher RS, Wickham LA, Vaerman JP, Sullivan DA.

Invest Ophthalmol Vis Sci. 1994 Mar;35(3):1192-201.

PMID:
8125730
31.

Androgen regulation of secretory component mRNA levels in the rat lacrimal gland.

Gao J, Lambert RW, Wickham LA, Sullivan DA.

Adv Exp Med Biol. 1994;350:219-24. No abstract available.

PMID:
8030480
32.

Sialodacryoadenitis virus infection of rat lacrimal gland acinar cells.

Wickham LA, Huang Z, Lambert RW, Sullivan DA.

Adv Exp Med Biol. 1994;350:193-6. No abstract available.

PMID:
8030476
33.

Influence of the endocrine environment on herpes virus infection in rat lacrimal gland acinar cells.

Huang Z, Lambert RW, Wickham LA, Sullivan DA.

Adv Exp Med Biol. 1994;350:189-92. No abstract available.

PMID:
8030474
34.

Neural-endocrine control of secretory component synthesis by lacrimal gland acinar cells: specificity, temporal characteristics and molecular basis.

Lambert RW, Kelleher RS, Wickham LA, Gao J, Sullivan DA.

Adv Exp Med Biol. 1994;350:175-80. No abstract available.

PMID:
8030471
35.

Influence of gender and the endocrine environment on the distribution of androgen receptors in the lacrimal gland.

Rocha FJ, Wickham LA, Pena JD, Gao J, Ono M, Lambert RW, Kelleher RS, Sullivan DA.

J Steroid Biochem Mol Biol. 1993 Dec;46(6):737-49.

PMID:
8274407

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