Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 223


Chronic Immune Activation in Systemic Lupus Erythematosus and the Autoimmune PTPN22 Trp620 Risk Allele Drive the Expansion of FOXP3+ Regulatory T Cells and PD-1 Expression.

Ferreira RC, Castro Dopico X, Oliveira JJ, Rainbow DB, Yang JH, Trzupek D, Todd SA, McNeill M, Steri M, Orrù V, Fiorillo E, Crouch DJM, Pekalski ML, Cucca F, Tree TI, Vyse TJ, Wicker LS, Todd JA.

Front Immunol. 2019 Nov 8;10:2606. doi: 10.3389/fimmu.2019.02606. eCollection 2019.


Genetic Variants Predisposing Most Strongly to Type 1 Diabetes Diagnosed Under Age 7 Years Lie Near Candidate Genes That Function in the Immune System and in Pancreatic β-Cells.

Inshaw JRJ, Cutler AJ, Crouch DJM, Wicker LS, Todd JA.

Diabetes Care. 2020 Jan;43(1):169-177. doi: 10.2337/dc19-0803. Epub 2019 Sep 26.


Effect of enzyme de-esterified pectin on the electrostatic complexation with pea protein isolate under different mixing conditions.

Pillai PKS, Morales-Contreras BE, Wicker L, Nickerson MT.

Food Chem. 2020 Feb 1;305:125433. doi: 10.1016/j.foodchem.2019.125433. Epub 2019 Aug 28.


Blueberry pectin and increased anthocyanins stability under in vitro digestion.

Koh J, Xu Z, Wicker L.

Food Chem. 2020 Jan 1;302:125343. doi: 10.1016/j.foodchem.2019.125343. Epub 2019 Aug 12.


Stochastic search and joint fine-mapping increases accuracy and identifies previously unreported associations in immune-mediated diseases.

Asimit JL, Rainbow DB, Fortune MD, Grinberg NF, Wicker LS, Wallace C.

Nat Commun. 2019 Jul 19;10(1):3216. doi: 10.1038/s41467-019-11271-0.


Genetic and functional data identifying Cd101 as a type 1 diabetes (T1D) susceptibility gene in nonobese diabetic (NOD) mice.

Mattner J, Mohammed JP, Fusakio ME, Giessler C, Hackstein CP, Opoka R, Wrage M, Schey R, Clark J, Fraser HI, Rainbow DB, Wicker LS.

PLoS Genet. 2019 Jun 14;15(6):e1008178. doi: 10.1371/journal.pgen.1008178. eCollection 2019 Jun.


Blueberry Pectin Extraction Methods Influence Physico-Chemical Properties.

Koh J, Xu Z, Wicker L.

J Food Sci. 2018 Dec;83(12):2954-2962. doi: 10.1111/1750-3841.14380. Epub 2018 Nov 21.


A long-lived IL-2 mutein that selectively activates and expands regulatory T cells as a therapy for autoimmune disease.

Peterson LB, Bell CJM, Howlett SK, Pekalski ML, Brady K, Hinton H, Sauter D, Todd JA, Umana P, Ast O, Waldhauer I, Freimoser-Grundschober A, Moessner E, Klein C, Hosse RJ, Wicker LS.

J Autoimmun. 2018 Dec;95:1-14. doi: 10.1016/j.jaut.2018.10.017. Epub 2018 Nov 13.


Ixodes heathi n. sp. (Acari: Ixodidae), a co-endangered tick from the critically endangered mountain pygmy possum (Burramys parvus), with notes on its biology and conservation.

Kwak ML, Madden C, Wicker L.

Exp Appl Acarol. 2018 Nov;76(3):413-419. doi: 10.1007/s10493-018-0312-5. Epub 2018 Oct 9.


The DILfrequency study is an adaptive trial to identify optimal IL-2 dosing in patients with type 1 diabetes.

Seelig E, Howlett J, Porter L, Truman L, Heywood J, Kennet J, Arbon EL, Anselmiova K, Walker NM, Atkar R, Pekalski ML, Rytina E, Evans M, Wicker LS, Todd JA, Mander AP, Bond S, Waldron-Lynch F.

JCI Insight. 2018 Oct 4;3(19). pii: 99306. doi: 10.1172/jci.insight.99306.


The plasma biomarker soluble SIGLEC-1 is associated with the type I interferon transcriptional signature, ethnic background and renal disease in systemic lupus erythematosus.

Oliveira JJ, Karrar S, Rainbow DB, Pinder CL, Clarke P, Rubio García A, Al-Assar O, Burling K, Morris S, Stratton R, Vyse TJ, Wicker LS, Todd JA, Ferreira RC.

Arthritis Res Ther. 2018 Jul 27;20(1):152. doi: 10.1186/s13075-018-1649-1.


A Novel Pkhd1 Mutation Interacts with the Nonobese Diabetic Genetic Background To Cause Autoimmune Cholangitis.

Huang W, Rainbow DB, Wu Y, Adams D, Shivakumar P, Kottyan L, Karns R, Aronow B, Bezerra J, Gershwin ME, Peterson LB, Wicker LS, Ridgway WM.

J Immunol. 2018 Jan 1;200(1):147-162. doi: 10.4049/jimmunol.1701087. Epub 2017 Nov 20.


Pectin from Husk Tomato (Physalis ixocarpa Brot.): Rheological behavior at different extraction conditions.

Morales-Contreras BE, Rosas-Flores W, Contreras-Esquivel JC, Wicker L, Morales-Castro J.

Carbohydr Polym. 2018 Jan 1;179:282-289. doi: 10.1016/j.carbpol.2017.09.097. Epub 2017 Sep 29.


Chromosome contacts in activated T cells identify autoimmune disease candidate genes.

Burren OS, Rubio García A, Javierre BM, Rainbow DB, Cairns J, Cooper NJ, Lambourne JJ, Schofield E, Castro Dopico X, Ferreira RC, Coulson R, Burden F, Rowlston SP, Downes K, Wingett SW, Frontini M, Ouwehand WH, Fraser P, Spivakov M, Todd JA, Wicker LS, Cutler AJ, Wallace C.

Genome Biol. 2017 Sep 4;18(1):165. doi: 10.1186/s13059-017-1285-0.


Capturing the systemic immune signature of a norovirus infection: an n-of-1 case study within a clinical trial.

Cutler AJ, Oliveira J, Ferreira RC, Challis B, Walker NM, Caddy S, Lu J, Stevens HE, Smyth DJ, Pekalski ML, Kennet J, Hunter KMD, Goodfellow I, Wicker LS, Todd JA, Waldron-Lynch F.

Wellcome Open Res. 2017 Oct 5;2:28. doi: 10.12688/wellcomeopenres.11300.3. eCollection 2017.


Neonatal and adult recent thymic emigrants produce IL-8 and express complement receptors CR1 and CR2.

Pekalski ML, García AR, Ferreira RC, Rainbow DB, Smyth DJ, Mashar M, Brady J, Savinykh N, Dopico XC, Mahmood S, Duley S, Stevens HE, Walker NM, Cutler AJ, Waldron-Lynch F, Dunger DB, Shannon-Lowe C, Coles AJ, Jones JL, Wallace C, Todd JA, Wicker LS.

JCI Insight. 2017 Aug 17;2(16). pii: 93739. doi: 10.1172/jci.insight.93739. eCollection 2017 Aug 17.


Cells with Treg-specific FOXP3 demethylation but low CD25 are prevalent in autoimmunity.

Ferreira RC, Simons HZ, Thompson WS, Rainbow DB, Yang X, Cutler AJ, Oliveira J, Castro Dopico X, Smyth DJ, Savinykh N, Mashar M, Vyse TJ, Dunger DB, Baxendale H, Chandra A, Wallace C, Todd JA, Wicker LS, Pekalski ML.

J Autoimmun. 2017 Nov;84:75-86. doi: 10.1016/j.jaut.2017.07.009. Epub 2017 Jul 23.


Husk Tomato (Physalis ixocarpa Brot.) Waste as a Promising Source of Pectin: Extraction and Physicochemical Characterization.

Morales-Contreras BE, Contreras-Esquivel JC, Wicker L, Ochoa-Martínez LA, Morales-Castro J.

J Food Sci. 2017 Jul;82(7):1594-1601. doi: 10.1111/1750-3841.13768. Epub 2017 Jun 6.


In-depth immunophenotyping data of IL-6R on the human peripheral regulatory T cell (Treg) compartment.

Ferreira RC, Rainbow DB, Rubio García A, Pekalski ML, Porter L, Oliveira JJ, Waldron-Lynch F, Wicker LS, Todd JA.

Data Brief. 2017 May 2;12:676-691. doi: 10.1016/j.dib.2017.04.043. eCollection 2017 Jun.


Human IL-6RhiTIGIT- CD4+CD127lowCD25+ T cells display potent in vitro suppressive capacity and a distinct Th17 profile.

Ferreira RC, Rainbow DB, Rubio García A, Pekalski ML, Porter L, Oliveira JJ, Waldron-Lynch F, Wicker LS, Todd JA.

Clin Immunol. 2017 Jun;179:25-39. doi: 10.1016/j.clim.2017.03.002. Epub 2017 Mar 9.


HPMC (hydroxypropyl methylcellulose) as a fat replacer improves the physical properties of low-fat tofu.

Shin WK, Wicker L, Kim Y.

J Sci Food Agric. 2017 Aug;97(11):3720-3726. doi: 10.1002/jsfa.8233. Epub 2017 Mar 8.



Wicker LV, Canfield PJ, Higgins DP.

Zoonoses Public Health. 2017 Jan 9. doi: 10.1111/zph.1_12321. [Epub ahead of print] No abstract available.


Comments to 'Potential Pathogens Reported in Species of the Family Viverridae and Their Implications for Human and Animal Health'.

Millán J, Wicker LV, Canfield PJ, Higgins DP.

Zoonoses Public Health. 2017 Nov;64(7):e1-e4. doi: 10.1111/zph.12321. Epub 2016 Dec 23. No abstract available.


Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial.

Todd JA, Evangelou M, Cutler AJ, Pekalski ML, Walker NM, Stevens HE, Porter L, Smyth DJ, Rainbow DB, Ferreira RC, Esposito L, Hunter KM, Loudon K, Irons K, Yang JH, Bell CJ, Schuilenburg H, Heywood J, Challis B, Neupane S, Clarke P, Coleman G, Dawson S, Goymer D, Anselmiova K, Kennet J, Brown J, Caddy SL, Lu J, Greatorex J, Goodfellow I, Wallace C, Tree TI, Evans M, Mander AP, Bond S, Wicker LS, Waldron-Lynch F.

PLoS Med. 2016 Oct 11;13(10):e1002139. doi: 10.1371/journal.pmed.1002139. eCollection 2016 Oct.


Palmyra palm (Borassus aethiopum Mart.) fruits: novel raw materials for the pectin industry.

Assoi S, Konan K, Agbo GN, Dodo H, Holser R, Wicker L.

J Sci Food Agric. 2017 May;97(7):2057-2067. doi: 10.1002/jsfa.8010. Epub 2016 Nov 16.


Potential Pathogens Reported in Species of the Family Viverridae and Their Implications for Human and Animal Health.

Wicker LV, Canfield PJ, Higgins DP.

Zoonoses Public Health. 2017 Mar;64(2):75-93. doi: 10.1111/zph.12290. Epub 2016 Jun 30. Review.


Green tea, red wine and lemon extracts reduce experimental tumor growth and cancer drug toxicity.

Zaletok SP, Gulua L, Wicker L, Shlyakhovenko VA, Gogol S, Orlovsky O, Karnaushenko OV, Verbinenko A, Milinevska V, Samoylenko O, Todor I, Turmanidze T.

Exp Oncol. 2015 Dec;37(4):262-71.


Protocol of the adaptive study of IL-2 dose frequency on regulatory T cells in type 1 diabetes (DILfrequency): a mechanistic, non-randomised, repeat dose, open-label, response-adaptive study.

Truman LA, Pekalski ML, Kareclas P, Evangelou M, Walker NM, Howlett J, Mander AP, Kennet J, Wicker LS, Bond S, Todd JA, Waldron-Lynch F.

BMJ Open. 2015 Dec 8;5(12):e009799. doi: 10.1136/bmjopen-2015-009799.


Intermolecular binding of blueberry pectin-rich fractions and anthocyanin.

Lin Z, Fischer J, Wicker L.

Food Chem. 2016 Mar 1;194:986-93. doi: 10.1016/j.foodchem.2015.08.113. Epub 2015 Sep 2.


Ptpn22 and Cd2 Variations Are Associated with Altered Protein Expression and Susceptibility to Type 1 Diabetes in Nonobese Diabetic Mice.

Fraser HI, Howlett S, Clark J, Rainbow DB, Stanford SM, Wu DJ, Hsieh YW, Maine CJ, Christensen M, Kuchroo V, Sherman LA, Podolin PL, Todd JA, Steward CA, Peterson LB, Bottini N, Wicker LS.

J Immunol. 2015 Nov 15;195(10):4841-52. doi: 10.4049/jimmunol.1402654. Epub 2015 Oct 5.


Epigenetic analysis of regulatory T cells using multiplex bisulfite sequencing.

Rainbow DB, Yang X, Burren O, Pekalski ML, Smyth DJ, Klarqvist MD, Penkett CJ, Brugger K, Martin H, Todd JA, Wallace C, Wicker LS.

Eur J Immunol. 2015 Nov;45(11):3200-3. doi: 10.1002/eji.201545646. Epub 2015 Oct 1. No abstract available.


Natural Variation in Interleukin-2 Sensitivity Influences Regulatory T-Cell Frequency and Function in Individuals With Long-standing Type 1 Diabetes.

Yang JH, Cutler AJ, Ferreira RC, Reading JL, Cooper NJ, Wallace C, Clarke P, Smyth DJ, Boyce CS, Gao GJ, Todd JA, Wicker LS, Tree TI.

Diabetes. 2015 Nov;64(11):3891-902. doi: 10.2337/db15-0516. Epub 2015 Jul 29.


Dissection of a Complex Disease Susceptibility Region Using a Bayesian Stochastic Search Approach to Fine Mapping.

Wallace C, Cutler AJ, Pontikos N, Pekalski ML, Burren OS, Cooper JD, García AR, Ferreira RC, Guo H, Walker NM, Smyth DJ, Rich SS, Onengut-Gumuscu S, Sawcer SJ, Ban M, Richardson S, Todd JA, Wicker LS.

PLoS Genet. 2015 Jun 24;11(6):e1005272. doi: 10.1371/journal.pgen.1005272. eCollection 2015 Jun.


Genome-wide transcriptional analyses of islet-specific CD4+ T cells identify Idd9 genes controlling diabetogenic T cell function.

Berry GJ, Frielle C, Luu T, Salzberg AC, Rainbow DB, Wicker LS, Waldner H.

J Immunol. 2015 Mar 15;194(6):2654-63. doi: 10.4049/jimmunol.1401288. Epub 2015 Feb 11.


IL-21 production by CD4+ effector T cells and frequency of circulating follicular helper T cells are increased in type 1 diabetes patients.

Ferreira RC, Simons HZ, Thompson WS, Cutler AJ, Dopico XC, Smyth DJ, Mashar M, Schuilenburg H, Walker NM, Dunger DB, Wallace C, Todd JA, Wicker LS, Pekalski ML.

Diabetologia. 2015 Apr;58(4):781-90. doi: 10.1007/s00125-015-3509-8. Epub 2015 Feb 6.


Sustained in vivo signaling by long-lived IL-2 induces prolonged increases of regulatory T cells.

Bell CJ, Sun Y, Nowak UM, Clark J, Howlett S, Pekalski ML, Yang X, Ast O, Waldhauer I, Freimoser-Grundschober A, Moessner E, Umana P, Klein C, Hosse RJ, Wicker LS, Peterson LB.

J Autoimmun. 2015 Jan;56:66-80. doi: 10.1016/j.jaut.2014.10.002. Epub 2014 Oct 30.


Foot-and-mouth disease in Asiatic black bears (Ursus thibetanus).

Officer K, Lan NT, Wicker L, Hoa NT, Weegenaar A, Robinson J, Ryoji Y, Loukopoulos P.

J Vet Diagn Invest. 2014 Sep;26(5):705-13. doi: 10.1177/1040638714547256. Epub 2014 Aug 18.


Genetic analysis of autoimmune type 1 diabetes mellitus in mice. 1991.

Todd JA, Aitman TJ, Cornall RJ, Ghosh S, Hall JR, Hearne CM, Knight AM, Love JM, McAleer MA, Prins JB, Rodrigues N, Lathrop M, Pressey A, DeLarato NH, Peterson LB, Wicker LS.

J Immunol. 2014 Jul 1;193(1):7-12. No abstract available.


Investigation of soluble and transmembrane CTLA-4 isoforms in serum and microvesicles.

Esposito L, Hunter KM, Clark J, Rainbow DB, Stevens H, Denesha J, Duley S, Dawson S, Coleman G, Nutland S, Bell GL, Moran C, Pekalski M, Todd JA, Wicker LS.

J Immunol. 2014 Jul 15;193(2):889-900. doi: 10.4049/jimmunol.1303389. Epub 2014 Jun 13.


Change in texture improvement of low-fat tofu by means of low-fat soymilk protein denaturation.

Shin WK, Yokoyama WH, Kim W, Wicker L, Kim Y.

J Sci Food Agric. 2015 Mar 30;95(5):1000-7. doi: 10.1002/jsfa.6780. Epub 2014 Jul 15.


Rationale and study design of the Adaptive study of IL-2 dose on regulatory T cells in type 1 diabetes (DILT1D): a non-randomised, open label, adaptive dose finding trial.

Waldron-Lynch F, Kareclas P, Irons K, Walker NM, Mander A, Wicker LS, Todd JA, Bond S.

BMJ Open. 2014 Jun 4;4(6):e005559. doi: 10.1136/bmjopen-2014-005559.


Multi-parametric flow cytometric and genetic investigation of the peripheral B cell compartment in human type 1 diabetes.

Thompson WS, Pekalski ML, Simons HZ, Smyth DJ, Castro-Dopico X, Guo H, Guy C, Dunger DB, Arif S, Peakman M, Wallace C, Wicker LS, Todd JA, Ferreira RC.

Clin Exp Immunol. 2014 Sep;177(3):571-85. doi: 10.1111/cei.12362.


Blockade of the programmed death-1 (PD1) pathway undermines potent genetic protection from type 1 diabetes.

Kochupurakkal NM, Kruger AJ, Tripathi S, Zhu B, Adams LT, Rainbow DB, Rossini A, Greiner DL, Sayegh MH, Wicker LS, Guleria I.

PLoS One. 2014 Feb 28;9(2):e89561. doi: 10.1371/journal.pone.0089561. eCollection 2014.


Quality attributes in breast muscle from broilers of an Arkansas randombred line varying in growth rate.

Phongpa-ngan P, Jung J, Anthony NB, Karnuah AB, Mulligan JH, Aggrey SE, Wicker L.

Poult Sci. 2014 Jan;93(1):187-93. doi: 10.3382/ps.2012-02683.


A type I interferon transcriptional signature precedes autoimmunity in children genetically at risk for type 1 diabetes.

Ferreira RC, Guo H, Coulson RM, Smyth DJ, Pekalski ML, Burren OS, Cutler AJ, Doecke JD, Flint S, McKinney EF, Lyons PA, Smith KG, Achenbach P, Beyerlein A, Dunger DB, Clayton DG, Wicker LS, Todd JA, Bonifacio E, Wallace C, Ziegler AG.

Diabetes. 2014 Jul;63(7):2538-50. doi: 10.2337/db13-1777. Epub 2014 Feb 21.


An interdisciplinary multidepartmental educational program toward baby friendly hospital designation.

Schoch DE, Lawhon G, Wicker LA, Yecco G.

Adv Neonatal Care. 2014 Feb;14(1):38-43. doi: 10.1097/ANC.0000000000000029.


GALACTURONOSYLTRANSFERASE-LIKE5 is involved in the production of Arabidopsis seed coat mucilage.

Kong Y, Zhou G, Abdeen AA, Schafhauser J, Richardson B, Atmodjo MA, Jung J, Wicker L, Mohnen D, Western T, Hahn MG.

Plant Physiol. 2013 Nov;163(3):1203-17. doi: 10.1104/pp.113.227041. Epub 2013 Oct 3.


Hydroxypropyl methylcellulose substituent analysis and rheological properties.

Akinosho H, Hawkins S, Wicker L.

Carbohydr Polym. 2013 Oct 15;98(1):276-81. doi: 10.1016/j.carbpol.2013.05.081. Epub 2013 Jun 6.


Fine mapping of type 1 diabetes regions Idd9.1 and Idd9.2 reveals genetic complexity.

Hamilton-Williams EE, Rainbow DB, Cheung J, Christensen M, Lyons PA, Peterson LB, Steward CA, Sherman LA, Wicker LS.

Mamm Genome. 2013 Oct;24(9-10):358-75. doi: 10.1007/s00335-013-9466-y. Epub 2013 Aug 11.

Supplemental Content

Loading ...
Support Center