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Items: 6


Employing a gain-of-function factor IX variant R338L to advance the efficacy and safety of hemophilia B human gene therapy: preclinical evaluation supporting an ongoing adeno-associated virus clinical trial.

Monahan PE, Sun J, Gui T, Hu G, Hannah WB, Wichlan DG, Wu Z, Grieger JC, Li C, Suwanmanee T, Stafford DW, Booth CJ, Samulski JJ, Kafri T, McPhee SW, Samulski RJ.

Hum Gene Ther. 2015 Feb;26(2):69-81. doi: 10.1089/hum.2014.106. Epub 2015 Jan 21.


1α,25-dihydroxyvitamin D3 (vitamin D3) catalyzes suppressive activity on human natural regulatory T cells, uniquely modulates cell cycle progression, and augments FOXP3.

Morales-Tirado V, Wichlan DG, Leimig TE, Street SE, Kasow KA, Riberdy JM.

Clin Immunol. 2011 Feb;138(2):212-21. doi: 10.1016/j.clim.2010.11.003. Epub 2010 Dec 16.


Efficient and reproducible large-scale isolation of human CD4+ CD25+ regulatory T cells with potent suppressor activity.

Wichlan DG, Roddam PL, Eldridge P, Handgretinger R, Riberdy JM.

J Immunol Methods. 2006 Aug 31;315(1-2):27-36. Epub 2006 Jul 21.


Effector CD8+ T cells recovered from an influenza pneumonia differentiate to a state of focused gene expression.

Marshall DR, Olivas E, Andreansky S, La Gruta NL, Neale GA, Gutierrez A, Wichlan DG, Wingo S, Cheng C, Doherty PC, Turner SJ.

Proc Natl Acad Sci U S A. 2005 Apr 26;102(17):6074-9. Epub 2005 Apr 14.


Identification of an early-stage gene of Chlamydia psittaci 6BC.

Wichlan DG, Hatch TP.

J Bacteriol. 1993 May;175(10):2936-42.


Developmental cycle-specific host-free RNA synthesis in Chlamydia spp.

Crenshaw RW, Fahr MJ, Wichlan DG, Hatch TP.

Infect Immun. 1990 Oct;58(10):3194-201.

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