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Items: 1 to 50 of 206

1.

Cancer Stem Cell Vaccination With PD-L1 and CTLA-4 Blockades Enhances the Eradication of Melanoma Stem Cells in a Mouse Tumor Model.

Zheng F, Dang J, Zhang H, Xu F, Ba D, Zhang B, Cheng F, Chang AE, Wicha MS, Li Q.

J Immunother. 2018 Jul 30. doi: 10.1097/CJI.0000000000000242. [Epub ahead of print]

PMID:
30063587
2.

Targeting Breast Cancer Stem Cell State Equilibrium through Modulation of Redox Signaling.

Luo M, Shang L, Brooks MD, Jiagge E, Zhu Y, Buschhaus JM, Conley S, Fath MA, Davis A, Gheordunescu E, Wang Y, Harouaka R, Lozier A, Triner D, McDermott S, Merajver SD, Luker GD, Spitz DR, Wicha MS.

Cell Metab. 2018 Jul 3;28(1):69-86.e6. doi: 10.1016/j.cmet.2018.06.006.

PMID:
29972798
3.

FGFR signaling regulates resistance of head and neck cancer stem cells to cisplatin.

McDermott SC, Rodriguez-Ramirez C, McDermott SP, Wicha MS, Nör JE.

Oncotarget. 2018 May 18;9(38):25148-25165. doi: 10.18632/oncotarget.25358. eCollection 2018 May 18.

4.

Asparagine and Glutamine: Co-conspirators Fueling Metastasis.

Luo M, Brooks M, Wicha MS.

Cell Metab. 2018 May 1;27(5):947-949. doi: 10.1016/j.cmet.2018.04.012.

PMID:
29719230
5.

Heterogeneity of Human Breast Stem and Progenitor Cells as Revealed by Transcriptional Profiling.

Colacino JA, Azizi E, Brooks MD, Harouaka R, Fouladdel S, McDermott SP, Lee M, Hill D, Madden J, Boerner J, Cote ML, Sartor MA, Rozek LS, Wicha MS.

Stem Cell Reports. 2018 May 8;10(5):1596-1609. doi: 10.1016/j.stemcr.2018.03.001. Epub 2018 Mar 29.

6.

Tamoxifen and ERα36: Fertilizing the seeds of breast cancer metastasis.

Burness ML, Wicha MS.

Cell Res. 2018 Apr;28(4):391-392. doi: 10.1038/s41422-018-0028-4. No abstract available.

PMID:
29563540
7.

Transcriptional profiles of different states of cancer stem cells in triple-negative breast cancer.

Liu M, Liu Y, Deng L, Wang D, He X, Zhou L, Wicha MS, Bai F, Liu S.

Mol Cancer. 2018 Feb 23;17(1):65. doi: 10.1186/s12943-018-0809-x.

8.

Identification, isolation and characterization of human LGR5-positive colon adenoma cells.

Dame MK, Attili D, McClintock SD, Dedhia PH, Ouillette P, Hardt O, Chin AM, Xue X, Laliberte J, Katz EL, Newsome GM, Hill DR, Miller AJ, Tsai YH, Agorku D, Altheim CH, Bosio A, Simon B, Samuelson LC, Stoerker JA, Appelman HD, Varani J, Wicha MS, Brenner DE, Shah YM, Spence JR, Colacino JA.

Development. 2018 Mar 14;145(6). pii: dev153049. doi: 10.1242/dev.153049.

PMID:
29467240
9.

Modeling of Interactions between Cancer Stem Cells and their Microenvironment: Predicting Clinical Response.

Sehl ME, Wicha MS.

Methods Mol Biol. 2018;1711:333-349. doi: 10.1007/978-1-4939-7493-1_16.

PMID:
29344897
10.

Algorithm for cellular reprogramming.

Ronquist S, Patterson G, Muir LA, Lindsly S, Chen H, Brown M, Wicha MS, Bloch A, Brockett R, Rajapakse I.

Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):11832-11837. doi: 10.1073/pnas.1712350114. Epub 2017 Oct 24.

11.

A method to reduce ancestry related germline false positives in tumor only somatic variant calling.

Halperin RF, Carpten JD, Manojlovic Z, Aldrich J, Keats J, Byron S, Liang WS, Russell M, Enriquez D, Claasen A, Cherni I, Awuah B, Oppong J, Wicha MS, Newman LA, Jaigge E, Kim S, Craig DW.

BMC Med Genomics. 2017 Oct 19;10(1):61. doi: 10.1186/s12920-017-0296-8.

12.

IL6 blockade potentiates the anti-tumor effects of γ-secretase inhibitors in Notch3-expressing breast cancer.

Wang D, Xu J, Liu B, He X, Zhou L, Hu X, Qiao F, Zhang A, Xu X, Zhang H, Wicha MS, Zhang L, Shao ZM, Liu S.

Cell Death Differ. 2018 Feb;25(2):330-339. doi: 10.1038/cdd.2017.162. Epub 2017 Oct 13.

PMID:
29027990
13.

High-Throughput Microfluidic Labyrinth for the Label-free Isolation of Circulating Tumor Cells.

Lin E, Rivera-Báez L, Fouladdel S, Yoon HJ, Guthrie S, Wieger J, Deol Y, Keller E, Sahai V, Simeone DM, Burness ML, Azizi E, Wicha MS, Nagrath S.

Cell Syst. 2017 Sep 27;5(3):295-304.e4. doi: 10.1016/j.cels.2017.08.012. Epub 2017 Sep 20.

PMID:
28941584
14.

Inhibition of FAK kinase activity preferentially targets cancer stem cells.

Kolev VN, Tam WF, Wright QG, McDermott SP, Vidal CM, Shapiro IM, Xu Q, Wicha MS, Pachter JA, Weaver DT.

Oncotarget. 2017 Jun 16;8(31):51733-51747. doi: 10.18632/oncotarget.18517. eCollection 2017 Aug 1.

15.

Poor Prognosis Indicated by Venous Circulating Tumor Cell Clusters in Early-Stage Lung Cancers.

Murlidhar V, Reddy RM, Fouladdel S, Zhao L, Ishikawa MK, Grabauskiene S, Zhang Z, Lin J, Chang AC, Carrott P, Lynch WR, Orringer MB, Kumar-Sinha C, Palanisamy N, Beer DG, Wicha MS, Ramnath N, Azizi E, Nagrath S.

Cancer Res. 2017 Sep 15;77(18):5194-5206. doi: 10.1158/0008-5472.CAN-16-2072. Epub 2017 Jul 17.

PMID:
28716896
16.

Dendritic-cell-based immunotherapy evokes potent anti-tumor immune responses in CD105+ human renal cancer stem cells.

Zhang XF, Weng DS, Pan K, Zhou ZQ, Pan QZ, Zhao JJ, Tang Y, Jiang SS, Chen CL, Li YQ, Zhang HX, Chang AE, Wicha MS, Zeng YX, Li Q, Xia JC.

Mol Carcinog. 2017 Nov;56(11):2499-2511. doi: 10.1002/mc.22697. Epub 2017 Sep 14.

PMID:
28621442
17.

EMP2 is a novel therapeutic target for endometrial cancer stem cells.

Kiyohara MH, Dillard C, Tsui J, Kim SR, Lu J, Sachdev D, Goodglick L, Tong M, Torous VF, Aryasomayajula C, Wang W, Najafzadeh P, Gordon LK, Braun J, McDermott S, Wicha MS, Wadehra M.

Oncogene. 2017 Oct 19;36(42):5793-5807. doi: 10.1038/onc.2017.142. Epub 2017 Jun 12.

18.

Chemokines in the cancer microenvironment and their relevance in cancer immunotherapy.

Nagarsheth N, Wicha MS, Zou W.

Nat Rev Immunol. 2017 Sep;17(9):559-572. doi: 10.1038/nri.2017.49. Epub 2017 May 30. Review.

19.

Selective Photomechanical Detachment and Retrieval of Divided Sister Cells from Enclosed Microfluidics for Downstream Analyses.

Chen YC, Baac HW, Lee KT, Fouladdel S, Teichert K, Ok JG, Cheng YH, Ingram PN, Hart AJ, Azizi E, Guo LJ, Wicha MS, Yoon E.

ACS Nano. 2017 May 23;11(5):4660-4668. doi: 10.1021/acsnano.7b00413. Epub 2017 May 8.

PMID:
28480715
20.

Sulforaphane enhances the anticancer activity of taxanes against triple negative breast cancer by killing cancer stem cells.

Burnett JP, Lim G, Li Y, Shah RB, Lim R, Paholak HJ, McDermott SP, Sun L, Tsume Y, Bai S, Wicha MS, Sun D, Zhang T.

Cancer Lett. 2017 May 28;394:52-64. doi: 10.1016/j.canlet.2017.02.023. Epub 2017 Feb 27.

PMID:
28254410
21.

Single Amino Acid Variant Profiles of Subpopulations in the MCF-7 Breast Cancer Cell Line.

Tan Z, Nie S, McDermott SP, Wicha MS, Lubman DM.

J Proteome Res. 2017 Feb 3;16(2):842-851. doi: 10.1021/acs.jproteome.6b00824. Epub 2017 Jan 20.

22.

RAD51 Mediates Resistance of Cancer Stem Cells to PARP Inhibition in Triple-Negative Breast Cancer.

Liu Y, Burness ML, Martin-Trevino R, Guy J, Bai S, Harouaka R, Brooks MD, Shang L, Fox A, Luther TK, Davis A, Baker TL, Colacino J, Clouthier SG, Shao ZM, Wicha MS, Liu S.

Clin Cancer Res. 2017 Jan 15;23(2):514-522. doi: 10.1158/1078-0432.CCR-15-1348. Epub 2016 Dec 29.

23.

Patient-derived xenograft (PDX) models in basic and translational breast cancer research.

Dobrolecki LE, Airhart SD, Alferez DG, Aparicio S, Behbod F, Bentires-Alj M, Brisken C, Bult CJ, Cai S, Clarke RB, Dowst H, Ellis MJ, Gonzalez-Suarez E, Iggo RD, Kabos P, Li S, Lindeman GJ, Marangoni E, McCoy A, Meric-Bernstam F, Piwnica-Worms H, Poupon MF, Reis-Filho J, Sartorius CA, Scabia V, Sflomos G, Tu Y, Vaillant F, Visvader JE, Welm A, Wicha MS, Lewis MT.

Cancer Metastasis Rev. 2016 Dec;35(4):547-573. doi: 10.1007/s10555-016-9653-x. Review.

24.

5T4-Targeted Therapy Ablates Cancer Stem Cells and Prevents Recurrence of Head and Neck Squamous Cell Carcinoma.

Kerk SA, Finkel KA, Pearson AT, Warner KA, Zhang Z, Nör F, Wagner VP, Vargas PA, Wicha MS, Hurt EM, Hollingsworth RE, Tice DA, Nör JE.

Clin Cancer Res. 2017 May 15;23(10):2516-2527. doi: 10.1158/1078-0432.CCR-16-1834. Epub 2016 Oct 25.

25.

Elimination of epithelial-like and mesenchymal-like breast cancer stem cells to inhibit metastasis following nanoparticle-mediated photothermal therapy.

Paholak HJ, Stevers NO, Chen H, Burnett JP, He M, Korkaya H, McDermott SP, Deol Y, Clouthier SG, Luther T, Li Q, Wicha MS, Sun D.

Biomaterials. 2016 Oct;104:145-57. doi: 10.1016/j.biomaterials.2016.06.045. Epub 2016 Jun 23.

26.

Evaluation of the immunogenicity of ALDH(high) human head and neck squamous cell carcinoma cancer stem cells in vitro.

Prince MEP, Zhou L, Moyer JS, Tao H, Lu L, Owen J, Etigen M, Zheng F, Chang AE, Xia J, Wolf G, Wicha MS, Huang S, Ren X, Li Q.

Oral Oncol. 2016 Aug;59:30-42. doi: 10.1016/j.oraloncology.2016.05.013.

27.

Single cell dual adherent-suspension co-culture micro-environment for studying tumor-stromal interactions with functionally selected cancer stem-like cells.

Chen YC, Zhang Z, Fouladdel S, Deol Y, Ingram PN, McDermott SP, Azizi E, Wicha MS, Yoon E.

Lab Chip. 2016 Aug 7;16(15):2935-45. doi: 10.1039/c6lc00062b. Epub 2016 Jul 6.

28.

Therapeutic Efficacy of Cancer Stem Cell Vaccines in the Adjuvant Setting.

Hu Y, Lu L, Xia Y, Chen X, Chang AE, Hollingsworth RE, Hurt E, Owen J, Moyer JS, Prince ME, Dai F, Bao Y, Wang Y, Whitfield J, Xia JC, Huang S, Wicha MS, Li Q.

Cancer Res. 2016 Aug 15;76(16):4661-72. doi: 10.1158/0008-5472.CAN-15-2664. Epub 2016 Jun 20.

29.

Transcriptomic profiling of curcumin-treated human breast stem cells identifies a role for stearoyl-coa desaturase in breast cancer prevention.

Colacino JA, McDermott SP, Sartor MA, Wicha MS, Rozek LS.

Breast Cancer Res Treat. 2016 Jul;158(1):29-41. doi: 10.1007/s10549-016-3854-4. Epub 2016 Jun 15.

30.

High-Throughput Single-Cell Derived Sphere Formation for Cancer Stem-Like Cell Identification and Analysis.

Chen YC, Ingram PN, Fouladdel S, McDermott SP, Azizi E, Wicha MS, Yoon E.

Sci Rep. 2016 Jun 13;6:27301. doi: 10.1038/srep27301.

31.

Novel cancer stem cell targets during epithelial to mesenchymal transition in PTEN-deficient trastuzumab-resistant breast cancer.

Sun L, Burnett J, Gasparyan M, Xu F, Jiang H, Lin CC, Myers I, Korkaya H, Liu Y, Connarn J, He H, Zhang N, Wicha MS, Sun D.

Oncotarget. 2016 Aug 9;7(32):51408-51422. doi: 10.18632/oncotarget.9839.

32.

IL-6 Inhibition With MEDI5117 Decreases The Fraction of Head and Neck Cancer Stem Cells and Prevents Tumor Recurrence.

Finkel KA, Warner KA, Kerk S, Bradford CR, McLean SA, Prince ME, Zhong H, Hurt EM, Hollingsworth RE, Wicha MS, Tice DA, Nör JE.

Neoplasia. 2016 May;18(5):273-281. doi: 10.1016/j.neo.2016.03.004. Epub 2016 Apr 15.

33.

Tunable Thermal-Sensitive Polymer-Graphene Oxide Composite for Efficient Capture and Release of Viable Circulating Tumor Cells.

Yoon HJ, Shanker A, Wang Y, Kozminsky M, Jin Q, Palanisamy N, Burness ML, Azizi E, Simeone DM, Wicha MS, Kim J, Nagrath S.

Adv Mater. 2016 Jun;28(24):4891-7. doi: 10.1002/adma.201600658. Epub 2016 Apr 26.

34.

Integrin-linked kinase as a novel molecular switch of the IL-6-NF-κB signaling loop in breast cancer.

Hsu EC, Kulp SK, Huang HL, Tu HJ, Chao MW, Tseng YC, Yang MC, Salunke SB, Sullivan NJ, Chen WC, Zhang J, Teng CM, Fu WM, Sun D, Wicha MS, Shapiro CL, Chen CS.

Carcinogenesis. 2016 Apr;37(4):430-442. doi: 10.1093/carcin/bgw020. Epub 2016 Feb 19.

35.

Clinical predictors of long-term survival in HER2-positive metastatic breast cancer.

Murthy P, Kidwell KM, Schott AF, Merajver SD, Griggs JJ, Smerage JD, Van Poznak CH, Wicha MS, Hayes DF, Henry NL.

Breast Cancer Res Treat. 2016 Feb;155(3):589-95. doi: 10.1007/s10549-016-3705-3. Epub 2016 Feb 13.

36.

A Novel IL6 Antibody Sensitizes Multiple Tumor Types to Chemotherapy Including Trastuzumab-Resistant Tumors.

Zhong H, Davis A, Ouzounova M, Carrasco RA, Chen C, Breen S, Chang YS, Huang J, Liu Z, Yao Y, Hurt E, Moisan J, Fung M, Tice DA, Clouthier SG, Xiao Z, Wicha MS, Korkaya H, Hollingsworth RE.

Cancer Res. 2016 Jan 15;76(2):480-90. doi: 10.1158/0008-5472.CAN-15-0883. Epub 2016 Jan 7.

37.

Trastuzumab resistance induces EMT to transform HER2(+) PTEN(-) to a triple negative breast cancer that requires unique treatment options.

Burnett JP, Korkaya H, Ouzounova MD, Jiang H, Conley SJ, Newman BW, Sun L, Connarn JN, Chen CS, Zhang N, Wicha MS, Sun D.

Sci Rep. 2015 Nov 2;5:15821. doi: 10.1038/srep15821.

38.

Metabolic plasticity of cancer stem cells.

Luo M, Wicha MS.

Oncotarget. 2015 Nov 3;6(34):35141-2. doi: 10.18632/oncotarget.6177. No abstract available.

39.

Leptin and Adiponectin Modulate the Self-renewal of Normal Human Breast Epithelial Stem Cells.

Esper RM, Dame M, McClintock S, Holt PR, Dannenberg AJ, Wicha MS, Brenner DE.

Cancer Prev Res (Phila). 2015 Dec;8(12):1174-83. doi: 10.1158/1940-6207.CAPR-14-0334. Epub 2015 Oct 20.

40.

ALDH/CD44 identifies uniquely tumorigenic cancer stem cells in salivary gland mucoepidermoid carcinomas.

Adams A, Warner K, Pearson AT, Zhang Z, Kim HS, Mochizuki D, Basura G, Helman J, Mantesso A, Castilho RM, Wicha MS, Nör JE.

Oncotarget. 2015 Sep 29;6(29):26633-50. doi: 10.18632/oncotarget.5782.

41.

Modeling of Cancer Stem Cell State Transitions Predicts Therapeutic Response.

Sehl ME, Shimada M, Landeros A, Lange K, Wicha MS.

PLoS One. 2015 Sep 23;10(9):e0135797. doi: 10.1371/journal.pone.0135797. eCollection 2015.

42.

Transdifferentiation-Induced Neural Stem Cells Promote Recovery of Middle Cerebral Artery Stroke Rats.

Yao H, Gao M, Ma J, Zhang M, Li S, Wu B, Nie X, Jiao J, Zhao H, Wang S, Yang Y, Zhang Y, Sun Y, Wicha MS, Chang AE, Gao S, Li Q, Xu R.

PLoS One. 2015 Sep 9;10(9):e0137211. doi: 10.1371/journal.pone.0137211. eCollection 2015.

43.

Therapeutic Implications of Cellular Heterogeneity and Plasticity in Breast Cancer.

Brooks MD, Burness ML, Wicha MS.

Cell Stem Cell. 2015 Sep 3;17(3):260-71. doi: 10.1016/j.stem.2015.08.014. Review.

44.

Promise of cancer stem cell vaccine.

Zhou L, Lu L, Wicha MS, Chang AE, Xia JC, Ren X, Li Q.

Hum Vaccin Immunother. 2015;11(12):2796-9. doi: 10.1080/21645515.2015.1083661.

45.

A quantitative proteomics analysis of MCF7 breast cancer stem and progenitor cell populations.

Nie S, McDermott SP, Deol Y, Tan Z, Wicha MS, Lubman DM.

Proteomics. 2015 Nov;15(22):3772-83. doi: 10.1002/pmic.201500002. Epub 2015 Oct 7.

46.

Chemokines and cellular plasticity of ovarian cancer stem cells.

Zou W, Wicha MS.

Oncoscience. 2015 Jul 25;2(7):615-6. eCollection 2015. No abstract available.

47.

Function of Integrin-Linked Kinase in Modulating the Stemness of IL-6-Abundant Breast Cancer Cells by Regulating γ-Secretase-Mediated Notch1 Activation in Caveolae.

Hsu EC, Kulp SK, Huang HL, Tu HJ, Salunke SB, Sullivan NJ, Sun D, Wicha MS, Shapiro CL, Chen CS.

Neoplasia. 2015 Jun;17(6):497-508. doi: 10.1016/j.neo.2015.06.001.

48.

Breast cancer stem cells: current advances and clinical implications.

Luo M, Clouthier SG, Deol Y, Liu S, Nagrath S, Azizi E, Wicha MS.

Methods Mol Biol. 2015;1293:1-49. doi: 10.1007/978-1-4939-2519-3_1. Review.

PMID:
26040679
49.

Cancer stem cell vaccine inhibits metastases of primary tumors and induces humoral immune responses against cancer stem cells.

Lu L, Tao H, Chang AE, Hu Y, Shu G, Chen Q, Egenti M, Owen J, Moyer JS, Prince ME, Huang S, Wicha MS, Xia JC, Li Q.

Oncoimmunology. 2015 Jan 9;4(3):e990767. eCollection 2015 Mar.

50.

Tumor twitter: cellular communication in the breast cancer stem cell niche.

Brooks MD, Wicha MS.

Cancer Discov. 2015 May;5(5):469-71. doi: 10.1158/2159-8290.CD-15-0327.

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