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Items: 1 to 50 of 113

1.

Corrigendum to "Neuron and neuroblast numbers and cytogenesis in the dentate gyrus of aged APPswe/PS1dE9transgenic mice: Effect of long-term treatment with paroxetine" [Neurobiol Dis. 2017; 104: 50-60].

Olesen LØ, Sivasaravanaparan M, Severino M, Babcock AA, Bouzinova EV, West MJ, Wiborg O, Finsen B.

Neurobiol Dis. 2019 Apr;124:573. doi: 10.1016/j.nbd.2019.01.021. No abstract available.

PMID:
30717840
2.

Neurite atrophy in dorsal hippocampus of rat indicates incomplete recovery of chronic mild stress induced depression.

Khan AR, Hansen B, Danladi J, Chuhutin A, Wiborg O, Nyengaard JR, Jespersen SN.

NMR Biomed. 2019 Mar;32(3):e4057. doi: 10.1002/nbm.4057. Epub 2019 Feb 1. No abstract available.

PMID:
30707463
3.

BDNF+/- rats exhibit depressive phenotype and altered expression of genes relevant in mood disorders.

Martis LS, Wiborg O, Holmes MC, Harris AP.

Genes Brain Behav. 2019 Feb;18(2):e12546. doi: 10.1111/gbb.12546. Epub 2019 Jan 2.

PMID:
30548775
4.

Resilient and depressive-like rats show distinct cognitive impairments in the touchscreen paired-associates learning (PAL) task.

Martis LS, Brision C, Holmes MC, Wiborg O.

Neurobiol Learn Mem. 2018 Nov;155:287-296. doi: 10.1016/j.nlm.2018.08.014. Epub 2018 Aug 21.

PMID:
30138691
5.

Long-Term Stress Disrupts the Structural and Functional Integrity of GABAergic Neuronal Networks in the Medial Prefrontal Cortex of Rats.

Czéh B, Vardya I, Varga Z, Febbraro F, Csabai D, Martis LS, Højgaard K, Henningsen K, Bouzinova EV, Miseta A, Jensen K, Wiborg O.

Front Cell Neurosci. 2018 Jun 20;12:148. doi: 10.3389/fncel.2018.00148. eCollection 2018.

6.

Established amyloid-β pathology is unaffected by chronic treatment with the selective serotonin reuptake inhibitor paroxetine.

Severino M, Sivasaravanaparan M, Olesen LØ, von Linstow CU, Metaxas A, Bouzinova EV, Khan AM, Lambertsen KL, Babcock AA, Gramsbergen JB, Wiborg O, Finsen B.

Alzheimers Dement (N Y). 2018 May 24;4:215-223. doi: 10.1016/j.trci.2018.04.005. eCollection 2018.

7.

How do parents' educational fields affect the choice of educational field?

Helland H, Wiborg ØN.

Br J Sociol. 2019 Mar;70(2):481-501. doi: 10.1111/1468-4446.12370. Epub 2018 Apr 26.

PMID:
29700826
8.

Effectiveness of memantine on depression-like behavior, memory deficits and brain mRNA levels of BDNF and TrkB in rats subjected to repeated unpredictable stress.

Amidfar M, Kim YK, Wiborg O.

Pharmacol Rep. 2018 Jun;70(3):600-606. doi: 10.1016/j.pharep.2017.12.007. Epub 2017 Dec 20.

PMID:
29680698
9.

Reduced Synapse and Axon Numbers in the Prefrontal Cortex of Rats Subjected to a Chronic Stress Model for Depression.

Csabai D, Wiborg O, Czéh B.

Front Cell Neurosci. 2018 Jan 30;12:24. doi: 10.3389/fncel.2018.00024. eCollection 2018.

10.

Differential microstructural alterations in rat cerebral cortex in a model of chronic mild stress depression.

Khan AR, Kroenke CD, Wiborg O, Chuhutin A, Nyengaard JR, Hansen B, Jespersen SN.

PLoS One. 2018 Feb 12;13(2):e0192329. doi: 10.1371/journal.pone.0192329. eCollection 2018.

11.

Diffusion MRI and MR spectroscopy reveal microstructural and metabolic brain alterations in chronic mild stress exposed rats: A CMS recovery study.

Khan AR, Hansen B, Wiborg O, Kroenke CD, Jespersen SN.

Neuroimage. 2018 Feb 15;167:342-353. doi: 10.1016/j.neuroimage.2017.11.053. Epub 2017 Nov 28.

12.

Disturbances of diurnal phase markers, behavior, and clock genes in a rat model of depression; modulatory effects of agomelatine treatment.

Højgaard K, Christiansen SL, Bouzinova EV, Wiborg O.

Psychopharmacology (Berl). 2018 Mar;235(3):627-640. doi: 10.1007/s00213-017-4781-8. Epub 2017 Nov 19.

PMID:
29151193
13.

The effect of rat strain and stress exposure on performance in touchscreen tasks.

Martis LS, Krog S, Tran TP, Bouzinova E, Christiansen SL, Møller A, Holmes MC, Wiborg O.

Physiol Behav. 2018 Feb 1;184:83-90. doi: 10.1016/j.physbeh.2017.11.010. Epub 2017 Nov 10.

PMID:
29129610
14.

Neuronal substrates underlying stress resilience and susceptibility in rats.

Febbraro F, Svenningsen K, Tran TP, Wiborg O.

PLoS One. 2017 Jun 16;12(6):e0179434. doi: 10.1371/journal.pone.0179434. eCollection 2017.

15.

Blocking of carnitine palmitoyl transferase 1 potently reduces stress-induced depression in rat highlighting a pivotal role of lipid metabolism.

Mørkholt AS, Wiborg O, Nieland JGK, Nielsen S, Nieland JD.

Sci Rep. 2017 May 19;7(1):2158. doi: 10.1038/s41598-017-02343-6.

16.

Neuron and neuroblast numbers and cytogenesis in the dentate gyrus of aged APPswe/PS1dE9 transgenic mice: Effect of long-term treatment with paroxetine.

Olesen LØ, Sivasaravanaparan M, Severino M, Babcock AA, Bouzinova EV, West MJ, Wiborg O, Finsen B.

Neurobiol Dis. 2017 Aug;104:50-60. doi: 10.1016/j.nbd.2017.04.021. Epub 2017 Apr 28. Erratum in: Neurobiol Dis. 2019 Apr;124:573.

PMID:
28461249
17.

Behavioural Phenotyping of APPswe/PS1δE9 Mice: Age-Rrelated Changes and Effect of Long-Term Paroxetine Treatment.

Olesen LØ, Bouzinova EV, Severino M, Sivasaravanaparan M, Hasselstrøm JB, Finsen B, Wiborg O.

PLoS One. 2016 Nov 4;11(11):e0165144. doi: 10.1371/journal.pone.0165144. eCollection 2016.

18.

Electron Microscopic Analysis of Hippocampal Axo-Somatic Synapses in a Chronic Stress Model for Depression.

Csabai D, Seress L, Varga Z, Ábrahám H, Miseta A, Wiborg O, Czéh B.

Hippocampus. 2017 Jan;27(1):17-27. doi: 10.1002/hipo.22650. Epub 2016 Sep 15.

19.

Chronic stress affects the number of GABAergic neurons in the orbitofrontal cortex of rats.

Varga Z, Csabai D, Miseta A, Wiborg O, Czéh B.

Behav Brain Res. 2017 Jan 1;316:104-114. doi: 10.1016/j.bbr.2016.08.030. Epub 2016 Aug 20.

PMID:
27555539
20.

Summary of high field diffusion MRI and microscopy data demonstrate microstructural aberration in chronic mild stress rat brain.

Khan AR, Chuhutin A, Wiborg O, Kroenke CD, Nyengaard JR, Hansen B, Jespersen SN.

Data Brief. 2016 Jul 5;8:934-7. doi: 10.1016/j.dib.2016.06.061. eCollection 2016 Sep.

21.

MicroRNA Profiling in the Medial and Lateral Habenula of Rats Exposed to the Learned Helplessness Paradigm: Candidate Biomarkers for Susceptibility and Resilience to Inescapable Shock.

Svenningsen K, Venø MT, Henningsen K, Mallien AS, Jensen L, Christensen T, Kjems J, Vollmayr B, Wiborg O.

PLoS One. 2016 Aug 5;11(8):e0160318. doi: 10.1371/journal.pone.0160318. eCollection 2016.

22.

Biophysical modeling of high field diffusion MRI demonstrates micro-structural aberration in chronic mild stress rat brain.

Khan AR, Chuhutin A, Wiborg O, Kroenke CD, Nyengaard JR, Hansen B, Jespersen SN.

Neuroimage. 2016 Nov 15;142:421-430. doi: 10.1016/j.neuroimage.2016.07.001. Epub 2016 Jul 5.

23.

Altered Expression Pattern of Clock Genes in a Rat Model of Depression.

Christiansen SL, Bouzinova EV, Fahrenkrug J, Wiborg O.

Int J Neuropsychopharmacol. 2016 Dec 3;19(11). pii: pyw061. doi: 10.1093/ijnp/pyw061. Print 2016 Nov.

24.

Protein biomarkers of susceptibility and resilience to stress in a rat model of depression.

Palmfeldt J, Henningsen K, Eriksen SA, Müller HK, Wiborg O.

Mol Cell Neurosci. 2016 Jul;74:87-95. doi: 10.1016/j.mcn.2016.04.001. Epub 2016 Apr 20.

PMID:
27105822
25.

The touchscreen operant platform for assessing cognitive functions in a rat model of depression.

Tran TP, Christensen HL, Bertelsen FCB, Bouzinova E, Møller A, Wiborg O.

Physiol Behav. 2016 Jul 1;161:74-80. doi: 10.1016/j.physbeh.2016.03.032. Epub 2016 Apr 13.

PMID:
27083126
26.

Disturbed diurnal rhythm of three classical phase markers in the chronic mild stress rat model of depression.

Christiansen SL, Højgaard K, Wiborg O, Bouzinova EV.

Neurosci Res. 2016 Sep;110:43-8. doi: 10.1016/j.neures.2016.03.002. Epub 2016 Mar 23.

PMID:
27033803
27.

Chronic stress does not impair liver regeneration in rats.

Andersen KJ, Knudsen AR, Wiborg O, Mortensen FV.

Regen Med Res. 2015 Dec 2;3:2. doi: 10.1186/s40340-015-0011-8. eCollection 2015.

28.

Chronic selective serotonin reuptake inhibition modulates endothelial dysfunction and oxidative state in rat chronic mild stress model of depression.

Matchkov VV, Kravtsova VV, Wiborg O, Aalkjaer C, Bouzinova EV.

Am J Physiol Regul Integr Comp Physiol. 2015 Oct 15;309(8):R814-23. doi: 10.1152/ajpregu.00337.2014. Epub 2015 Aug 12.

29.

Animal models of major depression and their clinical implications.

Czéh B, Fuchs E, Wiborg O, Simon M.

Prog Neuropsychopharmacol Biol Psychiatry. 2016 Jan 4;64:293-310. doi: 10.1016/j.pnpbp.2015.04.004. Epub 2015 Apr 17. Review.

PMID:
25891248
30.

Presynaptic plasticity as a hallmark of rat stress susceptibility and antidepressant response.

Nieto-Gonzalez JL, Holm MM, Vardya I, Christensen T, Wiborg O, Jensen K.

PLoS One. 2015 Mar 5;10(3):e0119993. doi: 10.1371/journal.pone.0119993. eCollection 2015.

31.

A dualistic conformational response to substrate binding in the human serotonin transporter reveals a high affinity state for serotonin.

Bjerregaard H, Severinsen K, Said S, Wiborg O, Sinning S.

J Biol Chem. 2015 Mar 20;290(12):7747-55. doi: 10.1074/jbc.M114.573477. Epub 2015 Jan 22.

32.

Role of peripheral vascular resistance for the association between major depression and cardiovascular disease.

Bouzinova EV, Wiborg O, Aalkjaer C, Matchkov VV.

J Cardiovasc Pharmacol. 2015 Apr;65(4):299-307. doi: 10.1097/FJC.0000000000000187. Review.

33.

Chronic stress reduces the number of GABAergic interneurons in the adult rat hippocampus, dorsal-ventral and region-specific differences.

Czéh B, Varga ZK, Henningsen K, Kovács GL, Miseta A, Wiborg O.

Hippocampus. 2015 Mar;25(3):393-405. doi: 10.1002/hipo.22382. Epub 2014 Oct 31.

PMID:
25331166
34.

Differential regulation of the serotonin transporter by vesicle-associated membrane protein 2 in cells of neuronal versus non-neuronal origin.

Müller HK, Kragballe M, Fjorback AW, Wiborg O.

PLoS One. 2014 May 30;9(5):e97540. doi: 10.1371/journal.pone.0097540. eCollection 2014.

35.

Association between endothelial dysfunction and depression-like symptoms in chronic mild stress model of depression.

Bouzinova EV, Norregaard R, Boedtkjer DM, Razgovorova IA, Moeller AM, Kudryavtseva O, Wiborg O, Aalkjaer C, Matchkov VV.

Psychosom Med. 2014 May;76(4):268-76. doi: 10.1097/PSY.0000000000000062.

PMID:
24804883
36.

Diffusion kurtosis imaging and high-resolution MRI demonstrate structural aberrations of caudate putamen and amygdala after chronic mild stress.

Delgado y Palacios R, Verhoye M, Henningsen K, Wiborg O, Van der Linden A.

PLoS One. 2014 Apr 16;9(4):e95077. doi: 10.1371/journal.pone.0095077. eCollection 2014.

37.

Molecular profiling of the lateral habenula in a rat model of depression.

Christensen T, Jensen L, Bouzinova EV, Wiborg O.

PLoS One. 2013 Dec 5;8(12):e80666. doi: 10.1371/journal.pone.0080666. eCollection 2013.

38.

Binding of mazindol and analogs to the human serotonin and dopamine transporters.

Severinsen K, Koldsø H, Thorup KA, Schjøth-Eskesen C, Møller PT, Wiborg O, Jensen HH, Sinning S, Schiøtt B.

Mol Pharmacol. 2014 Feb;85(2):208-17. doi: 10.1124/mol.113.088922. Epub 2013 Nov 8.

PMID:
24214825
39.

Chronic mild stress for modeling anhedonia.

Wiborg O.

Cell Tissue Res. 2013 Oct;354(1):155-69. doi: 10.1007/s00441-013-1664-0. Epub 2013 Jun 26. Review.

PMID:
23801433
40.

Electroconvulsive stimulation reverses anhedonia and cognitive impairments in rats exposed to chronic mild stress.

Henningsen K, Woldbye DP, Wiborg O.

Eur Neuropsychopharmacol. 2013 Dec;23(12):1789-94. doi: 10.1016/j.euroneuro.2013.03.011. Epub 2013 Apr 15.

PMID:
23597878
41.

Vesicular signalling and immune modulation as hedonic fingerprints: proteomic profiling in the chronic mild stress depression model.

Bisgaard CF, Bak S, Christensen T, Jensen ON, Enghild JJ, Wiborg O.

J Psychopharmacol. 2012 Dec;26(12):1569-83. doi: 10.1177/0269881112460110. Epub 2012 Nov 8.

PMID:
23139383
42.

Low maternal care exacerbates adult stress susceptibility in the chronic mild stress rat model of depression.

Henningsen K, Dyrvig M, Bouzinova EV, Christiansen S, Christensen T, Andreasen JT, Palme R, Lichota J, Wiborg O.

Behav Pharmacol. 2012 Dec;23(8):735-43. doi: 10.1097/FBP.0b013e32835a5184.

PMID:
23075705
43.

Binding of the amphetamine-like 1-phenyl-piperazine to monoamine transporters.

Severinsen K, Kraft JF, Koldsø H, Vinberg KA, Rothman RB, Partilla JS, Wiborg O, Blough B, Schiøtt B, Sinning S.

ACS Chem Neurosci. 2012 Sep 19;3(9):693-705. Epub 2012 Jun 10.

44.

Chronic mild stress-induced depression-like symptoms in rats and abnormalities in catecholamine uptake in small arteries.

Bouzinova EV, Møller-Nielsen N, Boedtkjer DB, Broegger T, Wiborg O, Aalkjaer C, Matchkov VV.

Psychosom Med. 2012 Apr;74(3):278-87. doi: 10.1097/PSY.0b013e31824c40a9. Epub 2012 Mar 9.

PMID:
22408132
45.

Synergistic antidepressant-like action of gaboxadol and escitalopram.

Christensen T, Bétry C, Mnie-Filali O, Etievant A, Ebert B, Haddjeri N, Wiborg O.

Eur Neuropsychopharmacol. 2012 Oct;22(10):751-60. doi: 10.1016/j.euroneuro.2012.02.001. Epub 2012 Mar 9.

PMID:
22406239
46.

Candidate hippocampal biomarkers of susceptibility and resilience to stress in a rat model of depression.

Henningsen K, Palmfeldt J, Christiansen S, Baiges I, Bak S, Jensen ON, Gregersen N, Wiborg O.

Mol Cell Proteomics. 2012 Jul;11(7):M111.016428. doi: 10.1074/mcp.M111.016428. Epub 2012 Feb 6.

47.

Hippocampal neurogenesis increase with stereotypic behavior in mink (Neovison vison).

Malmkvist J, Brix B, Henningsen K, Wiborg O.

Behav Brain Res. 2012 Apr 15;229(2):359-64. doi: 10.1016/j.bbr.2012.01.027. Epub 2012 Jan 20.

PMID:
22285416
48.

Circadian activity of the hypothalamic-pituitary-adrenal axis is differentially affected in the rat chronic mild stress model of depression.

Christiansen S, Bouzinova EV, Palme R, Wiborg O.

Stress. 2012 Nov;15(6):647-57. doi: 10.3109/10253890.2011.654370. Epub 2012 Feb 23.

PMID:
22217141
49.

Biomarkers of anhedonic-like behavior, antidepressant drug refraction, and stress resilience in a rat model of depression.

Christensen T, Bisgaard CF, Wiborg O.

Neuroscience. 2011 Nov 24;196:66-79. doi: 10.1016/j.neuroscience.2011.08.024. Epub 2011 Aug 27.

PMID:
21889970
50.

Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder.

Packiarajan M, Marzabadi MR, Desai M, Lu Y, Noble SA, Wong WC, Jubian V, Chandrasena G, Wolinsky TD, Zhong H, Walker MW, Wiborg O, Andersen K.

Bioorg Med Chem Lett. 2011 Sep 15;21(18):5436-41. doi: 10.1016/j.bmcl.2011.06.124. Epub 2011 Jul 2.

PMID:
21782428

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