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Items: 1 to 50 of 153

1.

Drosophila Heterochromatin Stabilization Requires the Zinc-Finger Protein Small Ovary.

Benner L, Castro EA, Whitworth C, Venken KJT, Yang H, Fang J, Oliver B, Cook KR, Lerit DA.

Genetics. 2019 Nov;213(3):877-895. doi: 10.1534/genetics.119.302590. Epub 2019 Sep 26.

2.

Piloting a clinical laboratory method to evaluate the influence of potential modified risk tobacco products on smokers' quit-related motivation, choice, and behavior.

Ozga-Hess JE, Felicione NJ, Ferguson SG, Dino G, Elswick D, Whitworth C, Turiano N, Blank MD.

Addict Behav. 2019 Dec;99:106105. doi: 10.1016/j.addbeh.2019.106105. Epub 2019 Aug 21.

PMID:
31470240
3.

Publisher Correction: BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design.

Farnaby W, Koegl M, Roy MJ, Whitworth C, Diers E, Trainor N, Zollman D, Steurer S, Karolyi-Oezguer J, Riedmueller C, Gmaschitz T, Wachter J, Dank C, Galant M, Sharps B, Rumpel K, Traxler E, Gerstberger T, Schnitzer R, Petermann O, Greb P, Weinstabl H, Bader G, Zoephel A, Weiss-Puxbaum A, Ehrenhöfer-Wölfer K, Wöhrle S, Boehmelt G, Rinnenthal J, Arnhof H, Wiechens N, Wu MY, Owen-Hughes T, Ettmayer P, Pearson M, McConnell DB, Ciulli A.

Nat Chem Biol. 2019 Aug;15(8):846. doi: 10.1038/s41589-019-0329-z.

PMID:
31267096
4.

BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design.

Farnaby W, Koegl M, Roy MJ, Whitworth C, Diers E, Trainor N, Zollman D, Steurer S, Karolyi-Oezguer J, Riedmueller C, Gmaschitz T, Wachter J, Dank C, Galant M, Sharps B, Rumpel K, Traxler E, Gerstberger T, Schnitzer R, Petermann O, Greb P, Weinstabl H, Bader G, Zoephel A, Weiss-Puxbaum A, Ehrenhöfer-Wölfer K, Wöhrle S, Boehmelt G, Rinnenthal J, Arnhof H, Wiechens N, Wu MY, Owen-Hughes T, Ettmayer P, Pearson M, McConnell DB, Ciulli A.

Nat Chem Biol. 2019 Jul;15(7):672-680. doi: 10.1038/s41589-019-0294-6. Epub 2019 Jun 10. Erratum in: Nat Chem Biol. 2019 Jul 2;:.

PMID:
31178587
5.

Doublesex controls specification and maintenance of the gonad stem cell niches in Drosophila.

Camara N, Whitworth C, Dove A, Van Doren M.

Development. 2019 Jun 10;146(11). pii: dev170001. doi: 10.1242/dev.170001.

PMID:
31043421
6.

SPR-Measured Dissociation Kinetics of PROTAC Ternary Complexes Influence Target Degradation Rate.

Roy MJ, Winkler S, Hughes SJ, Whitworth C, Galant M, Farnaby W, Rumpel K, Ciulli A.

ACS Chem Biol. 2019 Mar 15;14(3):361-368. doi: 10.1021/acschembio.9b00092. Epub 2019 Feb 22.

7.

γδ T cells: an immunotherapeutic approach for HIV cure strategies.

Garrido C, Clohosey ML, Whitworth CP, Hudgens M, Margolis DM, Soriano-Sarabia N.

JCI Insight. 2018 Jun 21;3(12). pii: 120121. doi: 10.1172/jci.insight.120121. eCollection 2018 Jun 21.

8.

Differentiation-Induced Remodelling of Store-Operated Calcium Entry Is Independent of Neuronal or Glial Phenotype but Modulated by Cellular Context.

Whitworth CL, Redfern CPF, Cheek TR.

Mol Neurobiol. 2019 Feb;56(2):857-872. doi: 10.1007/s12035-018-1112-y. Epub 2018 May 26.

9.

The U.S. Culture Collection Network Responding to the Requirements of the Nagoya Protocol on Access and Benefit Sharing.

McCluskey K, Barker KB, Barton HA, Boundy-Mills K, Brown DR, Coddington JA, Cook K, Desmeth P, Geiser D, Glaeser JA, Greene S, Kang S, Lomas MW, Melcher U, Miller SE, Nobles DR Jr, Owens KJ, Reichman JH, da Silva M, Wertz J, Whitworth C, Smith D.

MBio. 2017 Aug 15;8(4). pii: e00982-17. doi: 10.1128/mBio.00982-17. Review.

10.

Control of a Novel Spermatocyte-Promoting Factor by the Male Germline Sex Determination Factor PHF7 of Drosophila melanogaster.

Yang SY, Chang YC, Wan YH, Whitworth C, Baxter EM, Primus S, Pi H, Van Doren M.

Genetics. 2017 Aug;206(4):1939-1949. doi: 10.1534/genetics.117.199935. Epub 2017 Jun 6.

11.

Effects of Gene Dose, Chromatin, and Network Topology on Expression in Drosophila melanogaster.

Lee H, Cho DY, Whitworth C, Eisman R, Phelps M, Roote J, Kaufman T, Cook K, Russell S, Przytycka T, Oliver B.

PLoS Genet. 2016 Sep 6;12(9):e1006295. doi: 10.1371/journal.pgen.1006295. eCollection 2016 Sep.

12.

A microRNA allele that emerged prior to apple domestication may underlie fruit size evolution.

Yao JL, Xu J, Cornille A, Tomes S, Karunairetnam S, Luo Z, Bassett H, Whitworth C, Rees-George J, Ranatunga C, Snirc A, Crowhurst R, de Silva N, Warren B, Deng C, Kumar S, Chagné D, Bus VG, Volz RK, Rikkerink EH, Gardiner SE, Giraud T, MacDiarmid R, Gleave AP.

Plant J. 2015 Oct;84(2):417-27. doi: 10.1111/tpj.13021.

13.

Sex- and tissue-specific functions of Drosophila doublesex transcription factor target genes.

Clough E, Jimenez E, Kim YA, Whitworth C, Neville MC, Hempel LU, Pavlou HJ, Chen ZX, Sturgill D, Dale RK, Smith HE, Przytycka TM, Goodwin SF, Van Doren M, Oliver B.

Dev Cell. 2014 Dec 22;31(6):761-73. doi: 10.1016/j.devcel.2014.11.021.

14.

Protecting West Virginians from secondhand smoke through regulation at the local level.

Whitworth CM, Holley G, Mickey CB.

W V Med J. 2014 Jul-Aug;110(4):30-5.

PMID:
25322585
15.

Flipping the doublesex switch with a piRNA.

Whitworth C, Oliver B.

Genome Biol. 2014 Jun 24;15(6):118. doi: 10.1186/gb4181.

16.

COX2 expression in neuroblastoma increases tumorigenicity but does not affect cell death in response to the COX2 inhibitor celecoxib.

Bell E, Ponthan F, Whitworth C, Tweddle DA, Lunec J, Redfern CP.

Clin Exp Metastasis. 2014 Aug;31(6):651-9. doi: 10.1007/s10585-014-9656-3. Epub 2014 May 25.

PMID:
24859418
17.

The impact of brief tobacco treatment training on practice behaviours, self-efficacy and attitudes among healthcare providers.

Payne TJ, Gaughf NW, Sutton MJ, Sheffer CE, Elci OU, Cropsey KL, Taylor S, Netters T, Whitworth C, Deutsch P, Crews KM.

Int J Clin Pract. 2014 Jul;68(7):882-9. doi: 10.1111/ijcp.12386. Epub 2014 Mar 3.

PMID:
24589010
18.

In vitro evaluation of three-dimensional single-walled carbon nanotube composites for bone tissue engineering.

Gupta A, Main BJ, Taylor BL, Gupta M, Whitworth CA, Cady C, Freeman JW, El-Amin SF 3rd.

J Biomed Mater Res A. 2014 Nov;102(11):4118-26. doi: 10.1002/jbm.a.35088. Epub 2014 Jan 28.

PMID:
24443220
19.

The delivery of renal replacement therapy in Scotland--why the geographic variation?

Boyd J, Mackinnon MW, Severn A, Traynor JP, Whitworth CE, Metcalfe W; Scottish Renal Registry.

QJM. 2013 Dec;106(12):1077-85. doi: 10.1093/qjmed/hct176. Epub 2013 Aug 22.

PMID:
23974056
20.

Cell survival signalling through PPARδ and arachidonic acid metabolites in neuroblastoma.

Bell E, Ponthan F, Whitworth C, Westermann F, Thomas H, Redfern CP.

PLoS One. 2013 Jul 9;8(7):e68859. doi: 10.1371/journal.pone.0068859. Print 2013.

21.

Novel genomic approaches unravel genetic architecture of complex traits in apple.

Kumar S, Garrick DJ, Bink MC, Whitworth C, Chagné D, Volz RK.

BMC Genomics. 2013 Jun 12;14:393. doi: 10.1186/1471-2164-14-393.

22.

Infection control: achieving best practice.

Whitworth C.

Prim Dent J. 2012 Oct;1(1):18-22. No abstract available.

PMID:
23720911
23.

Anti-TNF-α therapy for renal amyloid as a complication of Crohn's disease.

Blackmur JP, Chapman FA, Bellamy CO, Save V, Plevris JN, Shand AG, Whitworth C, Dhaun N.

QJM. 2014 Jan;107(1):57-9. doi: 10.1093/qjmed/hct112. Epub 2013 May 16. No abstract available.

PMID:
23681221
24.

Prospective management of end-stage renal failure within a conservative care programme.

Dhaun N, Mackenzie J, Goddard J, Whitworth C.

BMJ Qual Improv Rep. 2013 Aug 21;2(1). pii: u201182.w727. doi: 10.1136/bmjquality.u201182.w727. eCollection 2013.

25.

Development of sexual dimorphism in the Drosophila testis.

Whitworth C, Jimenez E, Van Doren M.

Spermatogenesis. 2012 Jul 1;2(3):129-136.

26.

4-Phenyl-7-azaindoles as potent, selective and bioavailable IKK2 inhibitors demonstrating good in vivo efficacy.

Liddle J, Bamborough P, Barker MD, Campos S, Chung CW, Cousins RP, Faulder P, Heathcote ML, Hobbs H, Holmes DS, Ioannou C, Ramirez-Molina C, Morse MA, Osborn R, Payne JJ, Pritchard JM, Rumsey WL, Tape DT, Vicentini G, Whitworth C, Williamson RA.

Bioorg Med Chem Lett. 2012 Aug 15;22(16):5222-6. doi: 10.1016/j.bmcl.2012.06.065. Epub 2012 Jun 26.

PMID:
22801646
27.

An uncommon cause of pleural effusions in a dialysis patient.

Chapman F, Blackmur JP, Fotheringham J, Watson S, Whitworth C, Dhaun N.

Lancet. 2012 Jul 14;380(9837):186. doi: 10.1016/S0140-6736(12)60403-6. No abstract available.

PMID:
22794247
28.

Genomic selection for fruit quality traits in apple (Malus×domestica Borkh.).

Kumar S, Chagné D, Bink MC, Volz RK, Whitworth C, Carlisle C.

PLoS One. 2012;7(5):e36674. doi: 10.1371/journal.pone.0036674. Epub 2012 May 4.

29.

Quiz Page October 2011: An under-recognized cause of CKD.

Lua J, Bellamy CO, Whitworth C, Dhaun N.

Am J Kidney Dis. 2011 Oct;58(4):A30-3. doi: 10.1053/j.ajkd.2011.04.026. No abstract available.

PMID:
21944970
30.

Go team! How an integrated care group turns the tide against cardiometabolic disorders.

Lewis M Jr, Whitworth C.

Med Econ. 2009 Nov 6;86(21):12, 14, 16-7. No abstract available.

PMID:
20027762
31.

Heritability and genetic and phenotypic correlations of apple (Malus x domestica) fruit volatiles in a genetically diverse breeding population.

Rowan DD, Hunt MB, Alspach PA, Whitworth CJ, Oraguzie NC.

J Agric Food Chem. 2009 Sep 9;57(17):7944-52. doi: 10.1021/jf901359r.

PMID:
19691324
32.

4-Phenyl-7-azaindoles as potent and selective IKK2 inhibitors.

Liddle J, Bamborough P, Barker MD, Campos S, Cousins RP, Cutler GJ, Hobbs H, Holmes DS, Ioannou C, Mellor GW, Morse MA, Payne JJ, Pritchard JM, Smith KJ, Tape DT, Whitworth C, Williamson RA.

Bioorg Med Chem Lett. 2009 May 1;19(9):2504-8. doi: 10.1016/j.bmcl.2009.03.034. Epub 2009 Mar 14.

PMID:
19349179
33.

Predicting mortality and uptake of renal replacement therapy in patients with stage 4 chronic kidney disease.

Conway B, Webster A, Ramsay G, Morgan N, Neary J, Whitworth C, Harty J.

Nephrol Dial Transplant. 2009 Jun;24(6):1930-7. doi: 10.1093/ndt/gfn772. Epub 2009 Jan 30.

PMID:
19181760
34.

Can protein contamination be removed from hand endodontic instruments?

Whitworth CL, Davies K, Palmer NO.

Prim Dent Care. 2009 Jan;16(1):7-12. doi: 10.1308/135576109786994569.

PMID:
19126346
35.

The creation of sexual dimorphism in the Drosophila soma.

Camara N, Whitworth C, Van Doren M.

Curr Top Dev Biol. 2008;83:65-107. doi: 10.1016/S0070-2153(08)00403-1.

PMID:
19118664
36.

Short interfering RNA against transient receptor potential vanilloid 1 attenuates cisplatin-induced hearing loss in the rat.

Mukherjea D, Jajoo S, Whitworth C, Bunch JR, Turner JG, Rybak LP, Ramkumar V.

J Neurosci. 2008 Dec 3;28(49):13056-65. doi: 10.1523/JNEUROSCI.1307-08.2008.

37.

Re: Research governance.

Palmer N, Whitworth C.

Br Dent J. 2007 Dec 8;203(11):622. No abstract available.

PMID:
18065966
38.

vCJD and dental treatment: where are we now?

Whitworth C.

Prim Dent Care. 2007 Jul;14(3):83-4. No abstract available.

PMID:
17650381
39.

Mapping a candidate gene (MdMYB10) for red flesh and foliage colour in apple.

Chagné D, Carlisle CM, Blond C, Volz RK, Whitworth CJ, Oraguzie NC, Crowhurst RN, Allan AC, Espley RV, Hellens RP, Gardiner SE.

BMC Genomics. 2007 Jul 3;8:212.

40.

UK Consensus Conference on Early Chronic Kidney Disease--6 and 7 February 2007.

Archibald G, Bartlett W, Brown A, Christie B, Elliott A, Griffith K, Pound S, Rappaport I, Robertson D, Semple Y, Slane P, Whitworth C, Williams B.

Nephrol Dial Transplant. 2007 Sep;22(9):2455-7. Epub 2007 Jun 8. No abstract available.

PMID:
17557775
41.

Ginkgo biloba extract (EGb 761) protects against cisplatin-induced ototoxicity in rats.

Huang X, Whitworth CA, Rybak LP.

Otol Neurotol. 2007 Sep;28(6):828-33.

PMID:
17450108
42.

Factor Xa inhibitors: S1 binding interactions of a series of N-{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl}sulfonamides.

Chan C, Borthwick AD, Brown D, Burns-Kurtis CL, Campbell M, Chaudry L, Chung CW, Convery MA, Hamblin JN, Johnstone L, Kelly HA, Kleanthous S, Patikis A, Patel C, Pateman AJ, Senger S, Shah GP, Toomey JR, Watson NS, Weston HE, Whitworth C, Young RJ, Zhou P.

J Med Chem. 2007 Apr 5;50(7):1546-57. Epub 2007 Mar 6.

PMID:
17338508
43.

An investigation of the decontamination of Siqveland matrix bands.

Whitworth CL, Davies K, Palmer NO, Martin MV.

Br Dent J. 2007 Feb 24;202(4):E12; discussion 220-1. Epub 2007 Feb 16.

PMID:
17308532
44.

Mechanisms of cisplatin-induced ototoxicity and prevention.

Rybak LP, Whitworth CA, Mukherjea D, Ramkumar V.

Hear Res. 2007 Apr;226(1-2):157-67. Epub 2006 Nov 17. Review.

PMID:
17113254
45.

Design and synthesis of orally active pyrrolidin-2-one-based factor Xa inhibitors.

Watson NS, Brown D, Campbell M, Chan C, Chaudry L, Convery MA, Fenwick R, Hamblin JN, Haslam C, Kelly HA, King NP, Kurtis CL, Leach AR, Manchee GR, Mason AM, Mitchell C, Patel C, Patel VK, Senger S, Shah GP, Weston HE, Whitworth C, Young RJ.

Bioorg Med Chem Lett. 2006 Jul 15;16(14):3784-8. Epub 2006 May 11.

PMID:
16697194
46.

Expression of the kidney injury molecule 1 in the rat cochlea and induction by cisplatin.

Mukherjea D, Whitworth CA, Nandish S, Dunaway GA, Rybak LP, Ramkumar V.

Neuroscience. 2006 May 12;139(2):733-40. Epub 2006 Feb 7.

PMID:
16464536
47.

Ototoxicity: therapeutic opportunities.

Rybak LP, Whitworth CA.

Drug Discov Today. 2005 Oct 1;10(19):1313-21. Review.

PMID:
16214676
48.

Partial protection by lipoic acid against carboplantin-induced ototoxicity in rats.

Husain K, Whitworth C, Somani SM, Rybak LP.

Biomed Environ Sci. 2005 Jun;18(3):198-206.

PMID:
16131024
49.

A comparison of decontamination methods used for dental burs.

Whitworth CL, Martin MV, Gallagher M, Worthington HV.

Br Dent J. 2004 Nov 27;197(10):635-40; discussion 623.

PMID:
15611751
50.

Fatal calcific uraemic arteriolopathy (CUA): a case report and review of the literature.

Lang N, Davie R, Whitworth C, Winney R, Hughes J.

Scott Med J. 2004 Aug;49(3):108-11. Review.

PMID:
15462229

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