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Items: 17


Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation.

Nonomura K, Lukacs V, Sweet DT, Goddard LM, Kanie A, Whitwam T, Ranade SS, Fujimori T, Kahn ML, Patapoutian A.

Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):12817-12822. doi: 10.1073/pnas.1817070115. Epub 2018 Nov 27.


OSCA/TMEM63 are an Evolutionarily Conserved Family of Mechanically Activated Ion Channels.

Murthy SE, Dubin AE, Whitwam T, Jojoa-Cruz S, Cahalan SM, Mousavi SAR, Ward AB, Patapoutian A.

Elife. 2018 Nov 1;7. pii: e41844. doi: 10.7554/eLife.41844.


Structure of the human volume regulated anion channel.

Kefauver JM, Saotome K, Dubin AE, Pallesen J, Cottrell CA, Cahalan SM, Qiu Z, Hong G, Crowley CS, Whitwam T, Lee WH, Ward AB, Patapoutian A.

Elife. 2018 Aug 10;7. pii: e38461. doi: 10.7554/eLife.38461.


Common PIEZO1 Allele in African Populations Causes RBC Dehydration and Attenuates Plasmodium Infection.

Ma S, Cahalan S, LaMonte G, Grubaugh ND, Zeng W, Murthy SE, Paytas E, Gamini R, Lukacs V, Whitwam T, Loud M, Lohia R, Berry L, Khan SM, Janse CJ, Bandell M, Schmedt C, Wengelnik K, Su AI, Honore E, Winzeler EA, Andersen KG, Patapoutian A.

Cell. 2018 Apr 5;173(2):443-455.e12. doi: 10.1016/j.cell.2018.02.047. Epub 2018 Mar 22.


Structure of the mechanically activated ion channel Piezo1.

Saotome K, Murthy SE, Kefauver JM, Whitwam T, Patapoutian A, Ward AB.

Nature. 2018 Feb 22;554(7693):481-486. doi: 10.1038/nature25453. Epub 2017 Dec 20.


An Atypical Tropomyosin in Drosophila with Intermediate Filament-like Properties.

Cho A, Kato M, Whitwam T, Kim JH, Montell DJ.

Cell Rep. 2016 Jul 26;16(4):928-938. doi: 10.1016/j.celrep.2016.06.054. Epub 2016 Jul 7.


Met amplification and tumor progression in Cdkn2a-deficient melanocytes.

Vanbrocklin MW, Robinson JP, Whitwam T, Guilbeault AR, Koeman J, Swiatek PJ, Vande Woude GF, Khoury JD, Holmen SL.

Pigment Cell Melanoma Res. 2009 Aug;22(4):454-60. doi: 10.1111/j.1755-148X.2009.00576.x. Epub 2009 Apr 29.


Differential oncogenic potential of activated RAS isoforms in melanocytes.

Whitwam T, Vanbrocklin MW, Russo ME, Haak PT, Bilgili D, Resau JH, Koo HM, Holmen SL.

Oncogene. 2007 Jul 5;26(31):4563-70. Epub 2007 Feb 5.


Long-term retinal transgene expression with FIV versus adenoviral vectors.

Loewen N, Leske DA, Cameron JD, Chen Y, Whitwam T, Simari RD, Teo WL, Fautsch MP, Poeschla EM, Holmes JM.

Mol Vis. 2004 Apr 13;10:272-80.


Unintegrated lentivirus DNA persistence and accessibility to expression in nondividing cells: analysis with class I integrase mutants.

Saenz DT, Loewen N, Peretz M, Whitwam T, Barraza R, Howell KG, Holmes JM, Good M, Poeschla EM.

J Virol. 2004 Mar;78(6):2906-20.


FIV Vectors.

Loewen N, Barraza R, Whitwam T, Saenz DT, Kemler I, Poeschla EM.

Methods Mol Biol. 2003;229:251-71. No abstract available.


Preservation of aqueous outflow facility after second-generation FIV vector-mediated expression of marker genes in anterior segments of human eyes.

Loewen N, Bahler C, Teo WL, Whitwam T, Peretz M, Xu R, Fautsch MP, Johnson DH, Poeschla EM.

Invest Ophthalmol Vis Sci. 2002 Dec;43(12):3686-90.


Drug selection with paclitaxel restores expression of linked IL-2 receptor gamma -chain and multidrug resistance (MDR1) transgenes in canine bone marrow.

Licht T, Haskins M, Henthorn P, Kleiman SE, Bodine DM, Whitwam T, Puck JM, Gottesman MM, Melniczek JR.

Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):3123-8. Epub 2002 Feb 26.


Identification of a central DNA flap in feline immunodeficiency virus.

Whitwam T, Peretz M, Poeschla E.

J Virol. 2001 Oct;75(19):9407-14.


Canine lymphocyte expression of retrovirally transferred human common gamma chain.

Whitwam T, Haskins ME, Henthorn PS, Bodine DM, Puck JM.

Ann N Y Acad Sci. 1999 Apr 30;872:387-90. No abstract available.


Retroviral marking of canine bone marrow: long-term, high-level expression of human interleukin-2 receptor common gamma chain in canine lymphocytes.

Whitwam T, Haskins ME, Henthorn PS, Kraszewski JN, Kleiman SE, Seidel NE, Bodine DM, Puck JM.

Blood. 1998 Sep 1;92(5):1565-75.


Mutation analysis of IL2RG in human X-linked severe combined immunodeficiency.

Puck JM, Pepper AE, Henthorn PS, Candotti F, Isakov J, Whitwam T, Conley ME, Fischer RE, Rosenblatt HM, Small TN, Buckley RH.

Blood. 1997 Mar 15;89(6):1968-77.

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