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Items: 50

1.

Epigenetic Mechanisms Within the Cingulate Cortex Regulate Innate Anxiety-Like Behavior.

Sah A, Sotnikov S, Kharitonova M, Schmuckermair C, Diepold RP, Landgraf R, Whittle N, Singewald N.

Int J Neuropsychopharmacol. 2019 Apr 1;22(4):317-328. doi: 10.1093/ijnp/pyz004.

2.

Improving interdepartmental communication following a patient death.

Whittle N.

Nurs Manag (Harrow). 2017 Jun 29;24(4):23-27. doi: 10.7748/nm.2017.e1586.

PMID:
28659072
3.

Pregnant and critically unwell.

Whittle N.

Midwives. 2017 Spring;20:68-70. No abstract available.

PMID:
30351832
4.

MicroRNA-Mediated Rescue of Fear Extinction Memory by miR-144-3p in Extinction-Impaired Mice.

Murphy CP, Li X, Maurer V, Oberhauser M, Gstir R, Wearick-Silva LE, Viola TW, Schafferer S, Grassi-Oliveira R, Whittle N, Hüttenhofer A, Bredy TW, Singewald N.

Biol Psychiatry. 2017 Jun 15;81(12):979-989. doi: 10.1016/j.biopsych.2016.12.021. Epub 2016 Dec 26.

5.

Enhancing dopaminergic signaling and histone acetylation promotes long-term rescue of deficient fear extinction.

Whittle N, Maurer V, Murphy C, Rainer J, Bindreither D, Hauschild M, Scharinger A, Oberhauser M, Keil T, Brehm C, Valovka T, Striessnig J, Singewald N.

Transl Psychiatry. 2016 Dec 6;6(12):e974. doi: 10.1038/tp.2016.231.

6.

Satb2 determines miRNA expression and long-term memory in the adult central nervous system.

Jaitner C, Reddy C, Abentung A, Whittle N, Rieder D, Delekate A, Korte M, Jain G, Fischer A, Sananbenesi F, Cera I, Singewald N, Dechant G, Apostolova G.

Elife. 2016 Nov 29;5. pii: e17361. doi: 10.7554/eLife.17361.

7.

Impaired Contextual Fear Extinction Learning is Associated with Aberrant Regulation of CHD-Type Chromatin Remodeling Factors.

Wille A, Maurer V, Piatti P, Whittle N, Rieder D, Singewald N, Lusser A.

Front Behav Neurosci. 2015 Nov 18;9:313. doi: 10.3389/fnbeh.2015.00313. eCollection 2015.

8.

Combined Neuropeptide S and D-Cycloserine Augmentation Prevents the Return of Fear in Extinction-Impaired Rodents: Advantage of Dual versus Single Drug Approaches.

Sartori SB, Maurer V, Murphy C, Schmuckermair C, Muigg P, Neumann ID, Whittle N, Singewald N.

Int J Neuropsychopharmacol. 2016 Jun 1;19(6). pii: pyv128. doi: 10.1093/ijnp/pyv128. Print 2016 Jun.

9.

Prefrontal inputs to the amygdala instruct fear extinction memory formation.

Bukalo O, Pinard CR, Silverstein S, Brehm C, Hartley ND, Whittle N, Colacicco G, Busch E, Patel S, Singewald N, Holmes A.

Sci Adv. 2015 Jul;1(6). pii: e1500251. Epub 2015 Jul 31.

10.

Pharmacology of cognitive enhancers for exposure-based therapy of fear, anxiety and trauma-related disorders.

Singewald N, Schmuckermair C, Whittle N, Holmes A, Ressler KJ.

Pharmacol Ther. 2015 May;149:150-90. doi: 10.1016/j.pharmthera.2014.12.004. Epub 2014 Dec 27. Review.

11.

Erratum to: Dietary magnesium restriction reduces amygdala-hypothalamic GluN1 receptor complex levels in mice.

Ghafari M, Whittle N, Miklósi AG, Kotlowski C, Schmuckermair C, Berger J, Bennett KL, Singewald N, Lubec G.

Brain Struct Funct. 2015 Jul;220(4):2223. doi: 10.1007/s00429-014-0820-y. No abstract available.

PMID:
24965486
12.

Dietary magnesium restriction reduces amygdala-hypothalamic GluN1 receptor complex levels in mice.

Ghafari M, Whittle N, Miklósi AG, Kotlowski C, Schmuckermair C, Berger J, Bennett KL, Singewald N, Lubec G.

Brain Struct Funct. 2015 Jul;220(4):2209-21. doi: 10.1007/s00429-014-0779-8. Epub 2014 May 8. Erratum in: Brain Struct Funct. 2015 Jul;220(4):2223. Kotlowsky, Caroline [Corrected to Kotlowski, Caroline].

PMID:
24807818
13.

HDAC inhibitors as cognitive enhancers in fear, anxiety and trauma therapy: where do we stand?

Whittle N, Singewald N.

Biochem Soc Trans. 2014 Apr;42(2):569-81. doi: 10.1042/BST20130233. Review.

14.

Prefrontal single-unit firing associated with deficient extinction in mice.

Fitzgerald PJ, Whittle N, Flynn SM, Graybeal C, Pinard CR, Gunduz-Cinar O, Kravitz AV, Singewald N, Holmes A.

Neurobiol Learn Mem. 2014 Sep;113:69-81. doi: 10.1016/j.nlm.2013.11.002. Epub 2013 Nov 11.

15.

Temporal factors in the extinction of fear in inbred mouse strains differing in extinction efficacy.

MacPherson K, Whittle N, Camp M, Gunduz-Cinar O, Singewald N, Holmes A.

Biol Mood Anxiety Disord. 2013 Jul 5;3(1):13. doi: 10.1186/2045-5380-3-13.

16.

Deep brain stimulation, histone deacetylase inhibitors and glutamatergic drugs rescue resistance to fear extinction in a genetic mouse model.

Whittle N, Schmuckermair C, Gunduz Cinar O, Hauschild M, Ferraguti F, Holmes A, Singewald N.

Neuropharmacology. 2013 Jan;64:414-23. doi: 10.1016/j.neuropharm.2012.06.001. Epub 2012 Jun 18.

17.

A Study of Young Offenders' Perceptions of Health and Health Care Services in Custody and in the Community.

Whittle N, Macdonald W, Bailey S.

J Correct Health Care. 2012 May 2. [Epub ahead of print]

PMID:
22553282
18.

Magnesium deficiency induces anxiety and HPA axis dysregulation: modulation by therapeutic drug treatment.

Sartori SB, Whittle N, Hetzenauer A, Singewald N.

Neuropharmacology. 2012 Jan;62(1):304-12. doi: 10.1016/j.neuropharm.2011.07.027. Epub 2011 Aug 4.

19.

Different fear states engage distinct networks within the intercalated cell clusters of the amygdala.

Busti D, Geracitano R, Whittle N, Dalezios Y, Mańko M, Kaufmann W, Sätzler K, Singewald N, Capogna M, Ferraguti F.

J Neurosci. 2011 Mar 30;31(13):5131-44. doi: 10.1523/JNEUROSCI.6100-10.2011.

20.

Changes in brain protein expression are linked to magnesium restriction-induced depression-like behavior.

Whittle N, Li L, Chen WQ, Yang JW, Sartori SB, Lubec G, Singewald N.

Amino Acids. 2011 Apr;40(4):1231-48. doi: 10.1007/s00726-010-0758-1. Epub 2011 Feb 11.

PMID:
21312047
21.

Rescue of impaired fear extinction and normalization of cortico-amygdala circuit dysfunction in a genetic mouse model by dietary zinc restriction.

Whittle N, Hauschild M, Lubec G, Holmes A, Singewald N.

J Neurosci. 2010 Oct 13;30(41):13586-96. doi: 10.1523/JNEUROSCI.0849-10.2010.

22.

GRACE: public health recovery methods following an environmental disaster.

Svendsen ER, Whittle NC, Sanders L, McKeown RE, Sprayberry K, Heim M, Caldwell R, Gibson JJ, Vena JE.

Arch Environ Occup Health. 2010 Apr-Jun;65(2):77-85. doi: 10.1080/19338240903390222.

23.

Impaired Pavlovian fear extinction is a common phenotype across genetic lineages of the 129 inbred mouse strain.

Camp M, Norcross M, Whittle N, Feyder M, D'Hanis W, Yilmazer-Hanke D, Singewald N, Holmes A.

Genes Brain Behav. 2009 Nov;8(8):744-52. doi: 10.1111/j.1601-183X.2009.00519.x. Epub 2009 Jun 26.

24.

Serotonin(1A)-receptor-dependent signaling proteins in mouse hippocampus.

Li L, Whittle N, Klug S, Chen WQ, Singewald N, Toth M, Lubec G.

Neuropharmacology. 2009 Oct-Nov;57(5-6):556-66. doi: 10.1016/j.neuropharm.2009.07.013. Epub 2009 Jul 14.

25.

Human fatality associated with Pacific ciguatoxin contaminated fish.

Hamilton B, Whittle N, Shaw G, Eaglesham G, Moore MR, Lewis RJ.

Toxicon. 2010 Oct;56(5):668-73. doi: 10.1016/j.toxicon.2009.06.007. Epub 2009 Jun 16.

PMID:
19538985
26.

Zinc deficiency induces enhanced depression-like behaviour and altered limbic activation reversed by antidepressant treatment in mice.

Whittle N, Lubec G, Singewald N.

Amino Acids. 2009 Jan;36(1):147-58. doi: 10.1007/s00726-008-0195-6. Epub 2008 Oct 31.

PMID:
18975044
27.

Conditional CRH overexpressing mice: an animal model for stress-elicited pathologies and treatments that target the central CRH system.

Lu A, Steiner MA, Whittle N, Vogl AM, Walser SM, Ableitner M, Refojo D, Ekker M, Rubenstein JL, Stalla GK, Singewald N, Holsboer F, Wotjak CT, Wurst W, Deussing JM.

Mol Psychiatry. 2008 Nov;13(11):989. doi: 10.1038/mp.2008.107. No abstract available.

PMID:
18936754
28.

Impaired fear extinction learning and cortico-amygdala circuit abnormalities in a common genetic mouse strain.

Hefner K, Whittle N, Juhasz J, Norcross M, Karlsson RM, Saksida LM, Bussey TJ, Singewald N, Holmes A.

J Neurosci. 2008 Aug 6;28(32):8074-85. doi: 10.1523/JNEUROSCI.4904-07.2008.

29.

Conditional mouse mutants highlight mechanisms of corticotropin-releasing hormone effects on stress-coping behavior.

Lu A, Steiner MA, Whittle N, Vogl AM, Walser SM, Ableitner M, Refojo D, Ekker M, Rubenstein JL, Stalla GK, Singewald N, Holsboer F, Wotjak CT, Wurst W, Deussing JM.

Mol Psychiatry. 2008 Nov;13(11):1028-42. doi: 10.1038/mp.2008.51. Epub 2008 May 13.

PMID:
18475271
30.

A developmental approach to violence, hostile attributions, and paranoid thinking in adolescence.

Bailey S, Whittle N, Farnworth P, Smedley K.

Behav Sci Law. 2007;25(6):913-29. Review.

PMID:
18046736
31.

Fetal Down syndrome brains exhibit aberrant levels of neurotransmitters critical for normal brain development.

Whittle N, Sartori SB, Dierssen M, Lubec G, Singewald N.

Pediatrics. 2007 Dec;120(6):e1465-71. Epub 2007 Nov 12.

PMID:
17998315
32.

Neurokinin 1 receptor antagonism promotes active stress coping via enhanced septal 5-HT transmission.

Ebner K, Singewald GM, Whittle N, Ferraguti F, Singewald N.

Neuropsychopharmacology. 2008 Jul;33(8):1929-41. Epub 2007 Oct 24.

33.

Ethnicity and its relevance in a seven-year admission cohort to an English national adolescent medium secure health service unit.

Chowdhury NA, Whittle N, McCarthy K, Bailey S, Harrington R.

Crim Behav Ment Health. 2005;15(4):261-72.

PMID:
16575847
34.

Enhancement of human papillomavirus (HPV) type 16 E6 and E7-specific T-cell immunity in healthy volunteers through vaccination with TA-CIN, an HPV16 L2E7E6 fusion protein vaccine.

de Jong A, O'Neill T, Khan AY, Kwappenberg KM, Chisholm SE, Whittle NR, Dobson JA, Jack LC, St Clair Roberts JA, Offringa R, van der Burg SH, Hickling JK.

Vaccine. 2002 Oct 4;20(29-30):3456-64.

PMID:
12297390
35.

Uptake of postnatal services for mothers of newborn babies up to eight weeks of age.

Turner N, Hounsell D, Robinson E, Tai A, Whittle N.

N Z Med J. 1999 Oct 22;112(1098):395-8.

PMID:
10606400
37.

Gene therapy--the gutless approach pays off.

Whittle N.

Trends Genet. 1998 Apr;14(4):136-7. No abstract available.

PMID:
9594660
38.

Regulation of growth and dissemination of a human lymphoma by CD44 splice variants.

Bartolazzi A, Jackson D, Bennett K, Aruffo A, Dickinson R, Shields J, Whittle N, Stamenkovic I.

J Cell Sci. 1995 Apr;108 ( Pt 4):1723-33.

39.

Proteoglycan forms of the lymphocyte homing receptor CD44 are alternatively spliced variants containing the v3 exon.

Jackson DG, Bell JI, Dickinson R, Timans J, Shields J, Whittle N.

J Cell Biol. 1995 Feb;128(4):673-85.

40.

Generation and characterization of a recombinant/chimeric B72.3 (human gamma 1).

Hutzell P, Kashmiri S, Colcher D, Primus FJ, Hand PH, Roselli M, Finch M, Yarranton G, Bodmer M, Whittle N, et al.

Cancer Res. 1991 Jan 1;51(1):181-9.

41.

Site-specific attachment to recombinant antibodies via introduced surface cysteine residues.

Lyons A, King DJ, Owens RJ, Yarranton GT, Millican A, Whittle NR, Adair JR.

Protein Eng. 1990 Aug;3(8):703-8.

PMID:
2120698
42.

Characterization and biodistribution of recombinant and recombinant/chimeric constructs of monoclonal antibody B72.3.

Colcher D, Milenic D, Roselli M, Raubitschek A, Yarranton G, King D, Adair J, Whittle N, Bodmer M, Schlom J.

Cancer Res. 1989 Apr 1;49(7):1738-45.

43.

Expression in COS cells of a mouse-human chimaeric B72.3 antibody.

Whittle N, Adair J, Lloyd C, Jenkins L, Devine J, Schlom J, Raubitschek A, Colcher D, Bodmer M.

Protein Eng. 1987 Dec;1(6):499-505.

PMID:
3508296
44.

The human EGF receptor gene: structure of the 110 kb locus and identification of sequences regulating its transcription.

Haley J, Whittle N, Bennet P, Kinchington D, Ullrich A, Waterfield M.

Oncogene Res. 1987 Sep-Oct;1(4):375-96.

PMID:
3329716
45.

Megakaryoblastic transformation of myelofibrosis with expression of the c-sis oncogene.

Marcus RE, Hibbin JA, Matutes E, Whittle N, Waterfield MD, Goldman JM.

Scand J Haematol. 1986 Feb;36(2):186-93.

PMID:
2422734
46.

Expression of epidermal growth factor receptors on human cervical, ovarian, and vulval carcinomas.

Gullick WJ, Marsden JJ, Whittle N, Ward B, Bobrow L, Waterfield MD.

Cancer Res. 1986 Jan;46(1):285-92.

47.

The structure and function of the epidermal growth factor receptor studied by using antisynthetic peptide antibodies.

Gullick WJ, Downward J, Parker PJ, Whittle N, Kris R, Schlessinger J, Ullrich A, Waterfield MD.

Proc R Soc Lond B Biol Sci. 1985 Oct 22;226(1242):127-34.

PMID:
2866520
48.

Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin.

Libermann TA, Nusbaum HR, Razon N, Kris R, Lax I, Soreq H, Whittle N, Waterfield MD, Ullrich A, Schlessinger J.

Nature. 1985 Jan 10-18;313(5998):144-7.

PMID:
2981413
49.

Amplification and overexpression of the EGF receptor gene in primary human glioblastomas.

Libermann TA, Nusbaum HR, Razon N, Kris R, Lax I, Soreq H, Whittle N, Waterfield MD, Ullrich A, Schlessinger J.

J Cell Sci Suppl. 1985;3:161-72.

PMID:
3011820
50.

Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus.

Waterfield MD, Scrace GT, Whittle N, Stroobant P, Johnsson A, Wasteson A, Westermark B, Heldin CH, Huang JS, Deuel TF.

Nature. 1983 Jul 7-13;304(5921):35-9.

PMID:
6306471

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