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Second round results from the Manchester 'Lung Health Check' community-based targeted lung cancer screening pilot.

Crosbie PA, Balata H, Evison M, Atack M, Bayliss-Brideaux V, Colligan D, Duerden R, Eaglesfield J, Edwards T, Elton P, Foster J, Greaves M, Hayler G, Higgins C, Howells J, Irion K, Karunaratne D, Kelly J, King Z, Lyons J, Manson S, Mellor S, Miller D, Myerscough A, Newton T, O'Leary M, Pearson R, Pickford J, Sawyer R, Screaton NJ, Sharman A, Simmons M, Smith E, Taylor B, Taylor S, Walsham A, Watts A, Whittaker J, Yarnell L, Threlfall A, Barber PV, Tonge J, Booton R.

Thorax. 2018 Nov 12. pii: thoraxjnl-2018-212547. doi: 10.1136/thoraxjnl-2018-212547. [Epub ahead of print]


Short-term mortality, morbidity and recovery milestones following major lower limb amputation: A prospective evaluation of outcomes in a tertiary centre.

Whittaker JD, Tullett R, Patel N, Newman J, Garnham A, Wall M.

Ann Vasc Surg. 2018 Oct 17. pii: S0890-5096(18)30811-2. doi: 10.1016/j.avsg.2018.07.070. [Epub ahead of print]


A phase I study to assess the safety, tolerability, and pharmacokinetics of CXD101 in patients with advanced cancer.

Eyre TA, Collins GP, Gupta A, Coupe N, Sheikh S, Whittaker J, Wang LM, Campo L, Soilleux E, Tysoe F, Cousins R, La Thangue N, Folkes LK, Stratford MRL, Kerr D, Middleton MR.

Cancer. 2018 Oct 17. doi: 10.1002/cncr.31791. [Epub ahead of print]


Serum cartilage oligomeric matrix protein (COMP) expression in individuals who sustained a youth sport-related intra-articular knee injury 3-10 years previously and uninjured matched controls.

Laudon J, Whittaker JL, Ren G, Jaremko JL, Emery CA, Krawetz RJ.

Osteoarthritis Cartilage. 2018 Oct 11. pii: S1063-4584(18)31482-1. doi: 10.1016/j.joca.2018.09.011. [Epub ahead of print]


Targeted lung cancer screening selects individuals at high risk of cardiovascular disease.

Balata H, Blandin Knight S, Barber P, Colligan D, Crosbie EJ, Duerden R, Elton P, Evison M, Greaves M, Howells J, Irion K, Karunaratne D, Kirwan M, Macnab A, Mellor S, Miller C, Newton T, Novasio J, Sawyer R, Sharman A, Slevin K, Smith E, Taylor B, Taylor S, Tonge J, Walsham A, Waplington S, Whittaker J, Booton R, Crosbie PAJ.

Lung Cancer. 2018 Oct;124:148-153. doi: 10.1016/j.lungcan.2018.08.006. Epub 2018 Aug 8.


Health-related Outcomes following a Youth Sport-related Knee Injury.

Whittaker JL, Toomey CM, Nettel-Aguirre A, Jaremko JL, Doyle-Baker PK, Woodhouse LJ, Emery CA.

Med Sci Sports Exerc. 2018 Sep 19. doi: 10.1249/MSS.0000000000001787. [Epub ahead of print]


The Functional Connectivity Between the Nucleus Accumbens and the Ventromedial Prefrontal Cortex as an Endophenotype for Bipolar Disorder.

Whittaker JR, Foley SF, Ackling E, Murphy K, Caseras X.

Biol Psychiatry. 2018 Dec 1;84(11):803-809. doi: 10.1016/j.biopsych.2018.07.023. Epub 2018 Aug 7.


The BOLD response in primary motor cortex and supplementary motor area during kinesthetic motor imagery based graded fMRI neurofeedback.

Mehler DMA, Williams AN, Krause F, Lührs M, Wise RG, Turner DL, Linden DEJ, Whittaker JR.

Neuroimage. 2019 Jan 1;184:36-44. doi: 10.1016/j.neuroimage.2018.09.007. Epub 2018 Sep 8.


Learning curve with a new primary total knee arthroplasty implant: a multicenter perspective with more than 2000 patients.

Whittaker JP, Dwyer KA, Howard J, Huey V, Lesko J, Nunley RM, Verdonk P.

Arthroplast Today. 2018 Jul 9;4(3):348-353. doi: 10.1016/j.artd.2018.05.004. eCollection 2018 Sep.


Correction to: A Mixed Methods Evaluation of Early Childhood Abuse Prevention Within Evidence-Based Home Visiting Programs.

Matone M, Kellom K, Griffis H, Quarshie W, Faerber J, Gierlach P, Whittaker J, Rubin DM, Cronholm PF.

Matern Child Health J. 2018 Oct;22(Suppl 1):123. doi: 10.1007/s10995-018-2623-x.


Observation of topological phenomena in a programmable lattice of 1,800 qubits.

King AD, Carrasquilla J, Raymond J, Ozfidan I, Andriyash E, Berkley A, Reis M, Lanting T, Harris R, Altomare F, Boothby K, Bunyk PI, Enderud C, Fréchette A, Hoskinson E, Ladizinsky N, Oh T, Poulin-Lamarre G, Rich C, Sato Y, Smirnov AY, Swenson LJ, Volkmann MH, Whittaker J, Yao J, Ladizinsky E, Johnson MW, Hilton J, Amin MH.

Nature. 2018 Aug;560(7719):456-460. doi: 10.1038/s41586-018-0410-x. Epub 2018 Aug 22.


A Hierarchical Model To Understand the Processing of Polysaccharides/Protein-Based Films in Ionic Liquids.

Hadadi A, Whittaker JW, Verrill DE, Hu X, Larini L, Salas-de la Cruz D.

Biomacromolecules. 2018 Oct 8;19(10):3970-3982. doi: 10.1021/acs.biomac.8b00903. Epub 2018 Sep 5.


Recurrent Instability Episodes and Meniscal or Cartilage Damage After Anterior Cruciate Ligament Injury: A Systematic Review.

Sommerfeldt M, Raheem A, Whittaker J, Hui C, Otto D.

Orthop J Sports Med. 2018 Jul 24;6(7):2325967118786507. doi: 10.1177/2325967118786507. eCollection 2018 Jul. Review.


Influence of Perioperative Serum Magnesium for Cardiac and Noncardiac Morbidity and Mortality Following Emergency Peripheral Vascular Surgery.

Whittaker JD, Downes F, Becker H, Garnham A, Wall M.

J Cardiothorac Vasc Anesth. 2018 May 28. pii: S1053-0770(18)30375-6. doi: 10.1053/j.jvca.2018.05.042. [Epub ahead of print]


Phase transitions in a programmable quantum spin glass simulator.

Harris R, Sato Y, Berkley AJ, Reis M, Altomare F, Amin MH, Boothby K, Bunyk P, Deng C, Enderud C, Huang S, Hoskinson E, Johnson MW, Ladizinsky E, Ladizinsky N, Lanting T, Li R, Medina T, Molavi R, Neufeld R, Oh T, Pavlov I, Perminov I, Poulin-Lamarre G, Rich C, Smirnov A, Swenson L, Tsai N, Volkmann M, Whittaker J, Yao J.

Science. 2018 Jul 13;361(6398):162-165. doi: 10.1126/science.aat2025.


Elastically Flexible Crystals have Disparate Mechanisms of Molecular Movement Induced by Strain and Heat.

Brock AJ, Whittaker JJ, Powell JA, Pfrunder MC, Grosjean A, Parsons S, McMurtrie JC, Clegg JK.

Angew Chem Int Ed Engl. 2018 Aug 27;57(35):11325-11328. doi: 10.1002/anie.201806431. Epub 2018 Jul 30.


A Mixed Methods Evaluation of Early Childhood Abuse Prevention Within Evidence-Based Home Visiting Programs.

Matone M, Kellom K, Griffis H, Quarshie W, Faerber J, Gierlach P, Whittaker J, Rubin DM, Cronholm PF.

Matern Child Health J. 2018 Oct;22(Suppl 1):79-91. doi: 10.1007/s10995-018-2530-1. Erratum in: Matern Child Health J. 2018 Aug 28;:.


A cryptic Gondwana-forming orogen located in Antarctica.

Daczko NR, Halpin JA, Fitzsimons ICW, Whittaker JM.

Sci Rep. 2018 May 30;8(1):8371. doi: 10.1038/s41598-018-26530-1.


A qualitative investigation of the attitudes and beliefs about physical activity and post-traumatic osteoarthritis in young adults 3-10 years after an intra-articular knee injury.

Ezzat AM, Brussoni M, Whittaker JL, Emery CA.

Phys Ther Sport. 2018 Jul;32:98-108. doi: 10.1016/j.ptsp.2018.05.001. Epub 2018 May 4.


One- and two-stage surgical revision of peri-prosthetic joint infection of the hip: a pooled individual participant data analysis of 44 cohort studies.

Kunutsor SK, Whitehouse MR, Blom AW, Board T, Kay P, Wroblewski BM, Zeller V, Chen SY, Hsieh PH, Masri BA, Herman A, Jenny JY, Schwarzkopf R, Whittaker JP, Burston B, Huang R, Restrepo C, Parvizi J, Rudelli S, Honda E, Uip DE, Bori G, Muñoz-Mahamud E, Darley E, Ribera A, Cañas E, Cabo J, Cordero-Ampuero J, Redó MLS, Strange S, Lenguerrand E, Gooberman-Hill R, Webb J, MacGowan A, Dieppe P, Wilson M, Beswick AD; Global Infection Orthopaedic Management Collaboration.

Eur J Epidemiol. 2018 Oct;33(10):933-946. doi: 10.1007/s10654-018-0377-9. Epub 2018 Apr 5.


We need to talk about manels: the problem of implicit gender bias in sport and exercise medicine.

Bekker S, Ahmed OH, Bakare U, Blake TA, Brooks AM, Davenport TE, Mendonça LM, Fortington LV, Himawan M, Kemp JL, Litzy K, Loh RF, MacDonald J, McKay CD, Mosler AB, Mountjoy M, Pederson A, Stefan MI, Stokes E, Vassallo AJ, Whittaker JL.

Br J Sports Med. 2018 Oct;52(20):1287-1289. doi: 10.1136/bjsports-2018-099084. Epub 2018 Mar 17. No abstract available.


Structural evolution of photocrosslinked silk fibroin and silk fibroin-based hybrid hydrogels: A small angle and ultra-small angle scattering investigation.

Whittaker JL, Balu R, Knott R, de Campo L, Mata JP, Rehm C, Hill AJ, Dutta NK, Roy Choudhury N.

Int J Biol Macromol. 2018 Jul 15;114:998-1007. doi: 10.1016/j.ijbiomac.2018.03.044. Epub 2018 Mar 12.


Between-Day Reliability of Pre-Participation Screening Components in Pre-Professional Ballet and Contemporary Dancers.

Kenny SJ, Palacios-Derflingher L, Owoeye OBA, Whittaker JL, Emery CA.

J Dance Med Sci. 2018 Mar 15;22(1):54-62. doi: 10.12678/1089-313X.22.1.54.


Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference.

Corbin LJ, Tan VY, Hughes DA, Wade KH, Paul DS, Tansey KE, Butcher F, Dudbridge F, Howson JM, Jallow MW, John C, Kingston N, Lindgren CM, O'Donavan M, O'Rahilly S, Owen MJ, Palmer CNA, Pearson ER, Scott RA, van Heel DA, Whittaker J, Frayling T, Tobin MD, Wain LV, Smith GD, Evans DM, Karpe F, McCarthy MI, Danesh J, Franks PW, Timpson NJ.

Nat Commun. 2018 Feb 19;9(1):711. doi: 10.1038/s41467-018-03109-y. Review.


Implementing lung cancer screening: baseline results from a community-based 'Lung Health Check' pilot in deprived areas of Manchester.

Crosbie PA, Balata H, Evison M, Atack M, Bayliss-Brideaux V, Colligan D, Duerden R, Eaglesfield J, Edwards T, Elton P, Foster J, Greaves M, Hayler G, Higgins C, Howells J, Irion K, Karunaratne D, Kelly J, King Z, Manson S, Mellor S, Miller D, Myerscough A, Newton T, O'Leary M, Pearson R, Pickford J, Sawyer R, Screaton NJ, Sharman A, Simmons M, Smith E, Taylor B, Taylor S, Walsham A, Watts A, Whittaker J, Yarnell L, Threlfall A, Barber PV, Tonge J, Booton R.

Thorax. 2018 Feb 13. pii: thoraxjnl-2017-211377. doi: 10.1136/thoraxjnl-2017-211377. [Epub ahead of print]


The Influence of Injury Definition on Injury Burden in Preprofessional Ballet and Contemporary Dancers.

Kenny SJ, Palacios-Derflingher L, Whittaker JL, Emery CA.

J Orthop Sports Phys Ther. 2018 Mar;48(3):185-193. doi: 10.2519/jospt.2018.7542. Epub 2017 Dec 13.


Knee confidence in youth and young adults at risk of post-traumatic osteoarthritis 3-10 years following intra-articular knee injury.

Ezzat AM, Whittaker JL, Toomey C, Doyle-Baker PK, Brussoni M, Emery CA.

J Sci Med Sport. 2018 Jul;21(7):671-675. doi: 10.1016/j.jsams.2017.11.012. Epub 2017 Nov 26.


Gait Deviations Associated With Concussion: A Systematic Review.

Manaseer TS, Gross DP, Dennett L, Schneider K, Whittaker JL.

Clin J Sport Med. 2017 Nov 21. doi: 10.1097/JSM.0000000000000537. [Epub ahead of print]


An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native protein.

Glidden MD, Aldabbagh K, Phillips NB, Carr K, Chen YS, Whittaker J, Phillips M, Wickramasinghe NP, Rege N, Swain M, Peng Y, Yang Y, Lawrence MC, Yee VC, Ismail-Beigi F, Weiss MA.

J Biol Chem. 2018 Jan 5;293(1):47-68. doi: 10.1074/jbc.M117.808626. Epub 2017 Nov 7.


Association Between Previous Injury and Risk Factors for Future Injury in Preprofessional Ballet and Contemporary Dancers.

Kenny SJ, Palacios-Derflingher L, Shi Q, Whittaker JL, Emery CA.

Clin J Sport Med. 2017 Oct 20. doi: 10.1097/JSM.0000000000000513. [Epub ahead of print]


Association between MRI-defined osteoarthritis, pain, function and strength 3-10 years following knee joint injury in youth sport.

Whittaker JL, Toomey CM, Woodhouse LJ, Jaremko JL, Nettel-Aguirre A, Emery CA.

Br J Sports Med. 2018 Jul;52(14):934-939. doi: 10.1136/bjsports-2017-097576. Epub 2017 Oct 10.


Outcome after Turndown for Elective Abdominal Aortic Aneurysm Surgery.

Whittaker JD, Meecham L, Summerour V, Khalil S, Layton G, Yousif M, Jennings A, Wall M, Newman J.

Eur J Vasc Endovasc Surg. 2017 Nov;54(5):579-586. doi: 10.1016/j.ejvs.2017.07.023. Epub 2017 Sep 2.


Computational and experimental analysis of short peptide motifs for enzyme inhibition.

Fu J, Larini L, Cooper AJ, Whittaker JW, Ahmed A, Dong J, Lee M, Zhang T.

PLoS One. 2017 Aug 15;12(8):e0182847. doi: 10.1371/journal.pone.0182847. eCollection 2017.


Exercise Therapy in Juvenile Idiopathic Arthritis: A Systematic Review and Meta-Analysis.

Kuntze G, Nesbitt C, Whittaker JL, Nettel-Aguirre A, Toomey C, Esau S, Doyle-Baker PK, Shank J, Brooks J, Benseler S, Emery CA.

Arch Phys Med Rehabil. 2018 Jan;99(1):178-193.e1. doi: 10.1016/j.apmr.2017.05.030. Epub 2017 Jul 18. Review.


[Therapeutic Residential Care for Children and Youth: A Consensus Statement of the International Work Group on Therapeutic Residential Care].

Whittaker JK, Holmes L, Del Valle JF, Ainsworth F, Andreassen T, Anglin J, Bellonci C, Berridge D, Bravo A, Canali C, Courtney M, Currey L, Daly D, Gilligan R, Grietens H, Harder A, Holden M, James S, Kendrick A, Knorth E, Lausten M, Lyons J, Martin E, McDermid S, McNamara P, Palareti L, Ramsey S, Sisson K, Small R, Thoburn J, Thompson R, Zeira A.

Psicothema. 2017 Aug;29(3):289-298. doi: 10.7334/psicothema2016.172. Spanish.


Changes in arterial cerebral blood volume during lower body negative pressure measured with MRI.

Whittaker JR, Bright MG, Driver ID, Babic A, Khot S, Murphy K.

Neuroimage. 2017 Jun 28. pii: S1053-8119(17)30513-X. doi: 10.1016/j.neuroimage.2017.06.041. [Epub ahead of print]


Validation of an inertial measurement unit for the measurement of jump count and height.

MacDonald K, Bahr R, Baltich J, Whittaker JL, Meeuwisse WH.

Phys Ther Sport. 2017 May;25:15-19. doi: 10.1016/j.ptsp.2016.12.001. Epub 2016 Dec 7.


Impact of Phosphorylation and Pseudophosphorylation on the Early Stages of Aggregation of the Microtubule-Associated Protein Tau.

Prokopovich DV, Whittaker JW, Muthee MM, Ahmed A, Larini L.

J Phys Chem B. 2017 Mar 9;121(9):2095-2103. doi: 10.1021/acs.jpcb.7b00194. Epub 2017 Feb 24.


Higher Fat Mass Is Associated With a History of Knee Injury in Youth Sport.

Toomey CM, Whittaker JL, Nettel-Aguirre A, Reimer RA, Woodhouse LJ, Ghali B, Doyle-Baker PK, Emery CA.

J Orthop Sports Phys Ther. 2017 Feb;47(2):80-87. doi: 10.2519/jospt.2017.7101.


Intestinal Enterobacteriaceae that Protect Nematodes from the Effects of Benzimidazoles.

Whittaker JH, Robertson AP, Kimber MJ, Day TA, Carlson SA.

J Bacteriol Parasitol. 2016 Oct;7(5). pii: 294. doi: 10.4172/2155-9597.1000294. Epub 2016 Oct 31.


Changing Teacher-Child Dyadic Interactions to Improve Preschool Children's Externalizing Behaviors.

Williford AP, LoCasale-Crouch J, Whittaker JV, DeCoster J, Hartz KA, Carter LM, Wolcott CS, Hatfield BE.

Child Dev. 2017 Sep;88(5):1544-1553. doi: 10.1111/cdev.12703. Epub 2016 Dec 19.


Predicting sport and occupational lower extremity injury risk through movement quality screening: a systematic review.

Whittaker JL, Booysen N, de la Motte S, Dennett L, Lewis CL, Wilson D, McKay C, Warner M, Padua D, Emery CA, Stokes M.

Br J Sports Med. 2017 Apr;51(7):580-585. doi: 10.1136/bjsports-2016-096760. Epub 2016 Dec 1. Review.


Osteoarthritis: Models for appropriate care across the disease continuum.

Allen KD, Choong PF, Davis AM, Dowsey MM, Dziedzic KS, Emery C, Hunter DJ, Losina E, Page AE, Roos EM, Skou ST, Thorstensson CA, van der Esch M, Whittaker JL.

Best Pract Res Clin Rheumatol. 2016 Jun;30(3):503-535. doi: 10.1016/j.berh.2016.09.003. Review.


Extending Halogen-based Medicinal Chemistry to Proteins: IODO-INSULIN AS A CASE STUDY.

El Hage K, Pandyarajan V, Phillips NB, Smith BJ, Menting JG, Whittaker J, Lawrence MC, Meuwly M, Weiss MA.

J Biol Chem. 2016 Dec 30;291(53):27023-27041. doi: 10.1074/jbc.M116.761015. Epub 2016 Nov 14.


Neurofeedback training for alcohol dependence versus treatment as usual: study protocol for a randomized controlled trial.

Cox WM, Subramanian L, Linden DE, Lührs M, McNamara R, Playle R, Hood K, Watson G, Whittaker JR, Sakhuja R, Ihssen N.

Trials. 2016 Oct 3;17(1):480.


Arterial CO2 Fluctuations Modulate Neuronal Rhythmicity: Implications for MEG and fMRI Studies of Resting-State Networks.

Driver ID, Whittaker JR, Bright MG, Muthukumaraswamy SD, Murphy K.

J Neurosci. 2016 Aug 17;36(33):8541-50. doi: 10.1523/JNEUROSCI.4263-15.2016.


Running injuries in novice runners enrolled in different training interventions: a pilot randomized controlled trial.

Baltich J, Emery CA, Whittaker JL, Nigg BM.

Scand J Med Sci Sports. 2017 Nov;27(11):1372-1383. doi: 10.1111/sms.12743. Epub 2016 Aug 3.


Selecting instruments for Mendelian randomization in the wake of genome-wide association studies.

Swerdlow DI, Kuchenbaecker KB, Shah S, Sofat R, Holmes MV, White J, Mindell JS, Kivimaki M, Brunner EJ, Whittaker JC, Casas JP, Hingorani AD.

Int J Epidemiol. 2016 Oct;45(5):1600-1616. Epub 2016 Jun 24. Review.


Mendelian Randomisation study of the influence of eGFR on coronary heart disease.

Charoen P, Nitsch D, Engmann J, Shah T, White J, Zabaneh D, Jefferis B, Wannamethee G, Whincup P, Mulick Cassidy A, Gaunt T, Day I, McLachlan S, Price J, Kumari M, Kivimaki M, Brunner E, Langenberg C, Ben-Shlomo Y, Hingorani A, Whittaker J, Pablo Casas J, Dudbridge F; UCLEB Consortium.

Sci Rep. 2016 Jun 24;6:28514. doi: 10.1038/srep28514.


Molecular mechanisms for anthelmintic resistance in strongyle nematode parasites of veterinary importance.

Whittaker JH, Carlson SA, Jones DE, Brewer MT.

J Vet Pharmacol Ther. 2017 Apr;40(2):105-115. doi: 10.1111/jvp.12330. Epub 2016 Jun 15. Review.


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