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Items: 1 to 50 of 55

1.

Expansion of the CD4+ effector T cell repertoire characterizes peanut-allergic patients with heightened clinical sensitivity.

Ruiter B, Smith NP, Monian B, Tu AA, Fleming E, Virkud YV, Patil SU, Whittaker CA, Love JC, Shreffler WG.

J Allergy Clin Immunol. 2019 Oct 22. pii: S0091-6749(19)31331-4. doi: 10.1016/j.jaci.2019.09.033. [Epub ahead of print]

PMID:
31654649
2.

Comparative genome-scale analysis of Pichia pastoris variants informs selection of an optimal base strain.

Brady JR, Whittaker CA, Tan MC, Kristensen DL 2nd, Ma D, Dalvie NC, Love KR, Love JC.

Biotechnol Bioeng. 2019 Oct 26. doi: 10.1002/bit.27209. [Epub ahead of print]

PMID:
31654411
3.

Aneuploidy drives lethal progression in prostate cancer.

Stopsack KH, Whittaker CA, Gerke TA, Loda M, Kantoff PW, Mucci LA, Amon A.

Proc Natl Acad Sci U S A. 2019 Jun 4;116(23):11390-11395. doi: 10.1073/pnas.1902645116. Epub 2019 May 13.

4.

XBP1s activation can globally remodel N-glycan structure distribution patterns.

Wong MY, Chen K, Antonopoulos A, Kasper BT, Dewal MB, Taylor RJ, Whittaker CA, Hein PP, Dell A, Genereux JC, Haslam SM, Mahal LK, Shoulders MD.

Proc Natl Acad Sci U S A. 2018 Oct 23;115(43):E10089-E10098. doi: 10.1073/pnas.1805425115. Epub 2018 Oct 10.

5.

SIRT1 deacetylase in aging-induced neuromuscular degeneration and amyotrophic lateral sclerosis.

Herskovits AZ, Hunter TA, Maxwell N, Pereira K, Whittaker CA, Valdez G, Guarente LP.

Aging Cell. 2018 Dec;17(6):e12839. doi: 10.1111/acel.12839. Epub 2018 Oct 8.

6.

Destabilized adaptive influenza variants critical for innate immune system escape are potentiated by host chaperones.

Phillips AM, Ponomarenko AI, Chen K, Ashenberg O, Miao J, McHugh SM, Butty VL, Whittaker CA, Moore CL, Bloom JD, Lin YS, Shoulders MD.

PLoS Biol. 2018 Sep 17;16(9):e3000008. doi: 10.1371/journal.pbio.3000008. eCollection 2018 Sep.

7.

Comprehensive proteomic characterization of stem cell-derived extracellular matrices.

Ragelle H, Naba A, Larson BL, Zhou F, Prijić M, Whittaker CA, Del Rosario A, Langer R, Hynes RO, Anderson DG.

Biomaterials. 2017 Jun;128:147-159. doi: 10.1016/j.biomaterials.2017.03.008. Epub 2017 Mar 7.

PMID:
28327460
8.

Erratum to: Comparative genomics and transcriptomics of Pichia pastoris.

Love KR, Shah KA, Whittaker CA, Wu J, Bartlett MC, Ma D, Leeson RL, Priest M, Borowsky J, Young SK, Love JC.

BMC Genomics. 2016 Sep 28;17(1):762. No abstract available.

9.

Comparative genomics and transcriptomics of Pichia pastoris.

Love KR, Shah KA, Whittaker CA, Wu J, Bartlett MC, Ma D, Leeson RL, Priest M, Borowsky J, Young SK, Love JC.

BMC Genomics. 2016 Aug 5;17:550. doi: 10.1186/s12864-016-2876-y. Erratum in: BMC Genomics. 2016 Sep 28;17(1):762.

10.

Foxa2 and Cdx2 cooperate with Nkx2-1 to inhibit lung adenocarcinoma metastasis.

Li CM, Gocheva V, Oudin MJ, Bhutkar A, Wang SY, Date SR, Ng SR, Whittaker CA, Bronson RT, Snyder EL, Gertler FB, Jacks T.

Genes Dev. 2015 Sep 1;29(17):1850-62. doi: 10.1101/gad.267393.115.

11.

The extracellular matrix: Tools and insights for the "omics" era.

Naba A, Clauser KR, Ding H, Whittaker CA, Carr SA, Hynes RO.

Matrix Biol. 2016 Jan;49:10-24. doi: 10.1016/j.matbio.2015.06.003. Epub 2015 Jul 8. Review.

12.

Ligand orientation in a membrane-embedded receptor site revealed by solid-state NMR with paramagnetic relaxation enhancement.

Whittaker CA, Patching SG, Esmann M, Middleton DA.

Org Biomol Chem. 2015 Mar 7;13(9):2664-8. doi: 10.1039/c4ob02427c.

PMID:
25582619
13.

Single cell sequencing reveals low levels of aneuploidy across mammalian tissues.

Knouse KA, Wu J, Whittaker CA, Amon A.

Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13409-14. doi: 10.1073/pnas.1415287111. Epub 2014 Sep 2.

14.

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

Naba A, Clauser KR, Whittaker CA, Carr SA, Tanabe KK, Hynes RO.

BMC Cancer. 2014 Jul 18;14:518. doi: 10.1186/1471-2407-14-518.

15.

Comparative oncogenomic analysis of copy number alterations in human and zebrafish tumors enables cancer driver discovery.

Zhang G, Hoersch S, Amsterdam A, Whittaker CA, Beert E, Catchen JM, Farrington S, Postlethwait JH, Legius E, Hopkins N, Lees JA.

PLoS Genet. 2013 Aug;9(8):e1003734. doi: 10.1371/journal.pgen.1003734. Epub 2013 Aug 29.

16.

Differential Tks5 isoform expression contributes to metastatic invasion of lung adenocarcinoma.

Li CM, Chen G, Dayton TL, Kim-Kiselak C, Hoersch S, Whittaker CA, Bronson RT, Beer DG, Winslow MM, Jacks T.

Genes Dev. 2013 Jul 15;27(14):1557-67. doi: 10.1101/gad.222745.113.

17.

Let-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts.

Gurtan AM, Ravi A, Rahl PB, Bosson AD, JnBaptiste CK, Bhutkar A, Whittaker CA, Young RA, Sharp PA.

Genes Dev. 2013 Apr 15;27(8):941-54. doi: 10.1101/gad.215376.113.

18.

Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma.

Snyder EL, Watanabe H, Magendantz M, Hoersch S, Chen TA, Wang DG, Crowley D, Whittaker CA, Meyerson M, Kimura S, Jacks T.

Mol Cell. 2013 Apr 25;50(2):185-99. doi: 10.1016/j.molcel.2013.02.018. Epub 2013 Mar 21.

19.

Acquired MET expression confers resistance to EGFR inhibition in a mouse model of glioblastoma multiforme.

Jun HJ, Acquaviva J, Chi D, Lessard J, Zhu H, Woolfenden S, Bronson RT, Pfannl R, White F, Housman DE, Iyer L, Whittaker CA, Boskovitz A, Raval A, Charest A.

Oncogene. 2012 Jun 21;31(25):3039-50. doi: 10.1038/onc.2011.474. Epub 2011 Oct 24.

20.

The speech aversion hypothesis has explanatory power in a Minimal Speech Approach to aloof, non-verbal, severe autism.

Whittaker CA.

Med Hypotheses. 2012 Jan;78(1):15-22. doi: 10.1016/j.mehy.2011.09.031. Epub 2011 Oct 17.

PMID:
22004986
21.

Chronic activation of wild-type epidermal growth factor receptor and loss of Cdkn2a cause mouse glioblastoma formation.

Acquaviva J, Jun HJ, Lessard J, Ruiz R, Zhu H, Donovan M, Woolfenden S, Boskovitz A, Raval A, Bronson RT, Pfannl R, Whittaker CA, Housman DE, Charest A.

Cancer Res. 2011 Dec 1;71(23):7198-206. doi: 10.1158/0008-5472.CAN-11-1514. Epub 2011 Oct 10.

22.

Nuclear factor I/B is an oncogene in small cell lung cancer.

Dooley AL, Winslow MM, Chiang DY, Banerji S, Stransky N, Dayton TL, Snyder EL, Senna S, Whittaker CA, Bronson RT, Crowley D, Barretina J, Garraway L, Meyerson M, Jacks T.

Genes Dev. 2011 Jul 15;25(14):1470-5. doi: 10.1101/gad.2046711.

23.

Suppression of lung adenocarcinoma progression by Nkx2-1.

Winslow MM, Dayton TL, Verhaak RG, Kim-Kiselak C, Snyder EL, Feldser DM, Hubbard DD, DuPage MJ, Whittaker CA, Hoersch S, Yoon S, Crowley D, Bronson RT, Chiang DY, Meyerson M, Jacks T.

Nature. 2011 May 5;473(7345):101-4. doi: 10.1038/nature09881. Epub 2011 Apr 6.

24.

Essential roles of fibronectin in the development of the left-right embryonic body plan.

Pulina MV, Hou SY, Mittal A, Julich D, Whittaker CA, Holley SA, Hynes RO, Astrof S.

Dev Biol. 2011 Jun 15;354(2):208-20. doi: 10.1016/j.ydbio.2011.03.026. Epub 2011 Apr 3.

25.

A study of the membrane association and regulatory effect of the phospholemman cytoplasmic domain.

Hughes E, Whittaker CA, Barsukov IL, Esmann M, Middleton DA.

Biochim Biophys Acta. 2011 Apr;1808(4):1021-31. doi: 10.1016/j.bbamem.2010.11.024. Epub 2010 Dec 2.

26.

Stage-specific sensitivity to p53 restoration during lung cancer progression.

Feldser DM, Kostova KK, Winslow MM, Taylor SE, Cashman C, Whittaker CA, Sanchez-Rivera FJ, Resnick R, Bronson R, Hemann MT, Jacks T.

Nature. 2010 Nov 25;468(7323):572-5. doi: 10.1038/nature09535.

27.

Identification of aneuploidy-tolerating mutations.

Torres EM, Dephoure N, Panneerselvam A, Tucker CM, Whittaker CA, Gygi SP, Dunham MJ, Amon A.

Cell. 2010 Oct 1;143(1):71-83. doi: 10.1016/j.cell.2010.08.038. Epub 2010 Sep 16.

28.

Highly aneuploid zebrafish malignant peripheral nerve sheath tumors have genetic alterations similar to human cancers.

Zhang G, Hoersch S, Amsterdam A, Whittaker CA, Lees JA, Hopkins N.

Proc Natl Acad Sci U S A. 2010 Sep 28;107(39):16940-5. doi: 10.1073/pnas.1011548107. Epub 2010 Sep 13.

29.

Conservation and divergence of ADAM family proteins in the Xenopus genome.

Wei S, Whittaker CA, Xu G, Bridges LC, Shah A, White JM, Desimone DW.

BMC Evol Biol. 2010 Jul 14;10:211. doi: 10.1186/1471-2148-10-211.

30.

Endothelial alpha5 and alphav integrins cooperate in remodeling of the vasculature during development.

van der Flier A, Badu-Nkansah K, Whittaker CA, Crowley D, Bronson RT, Lacy-Hulbert A, Hynes RO.

Development. 2010 Jul;137(14):2439-49. doi: 10.1242/dev.049551.

31.

Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer.

Oliver TG, Mercer KL, Sayles LC, Burke JR, Mendus D, Lovejoy KS, Cheng MH, Subramanian A, Mu D, Powers S, Crowley D, Bronson RT, Whittaker CA, Bhutkar A, Lippard SJ, Golub T, Thomale J, Jacks T, Sweet-Cordero EA.

Genes Dev. 2010 Apr 15;24(8):837-52. doi: 10.1101/gad.1897010.

32.

Gene expression analysis of macrophages that facilitate tumor invasion supports a role for Wnt-signaling in mediating their activity in primary mammary tumors.

Ojalvo LS, Whittaker CA, Condeelis JS, Pollard JW.

J Immunol. 2010 Jan 15;184(2):702-12. doi: 10.4049/jimmunol.0902360. Epub 2009 Dec 16.

33.

Aneuploidy affects proliferation and spontaneous immortalization in mammalian cells.

Williams BR, Prabhu VR, Hunter KE, Glazier CM, Whittaker CA, Housman DE, Amon A.

Science. 2008 Oct 31;322(5902):703-9. doi: 10.1126/science.1160058.

34.

Genomic predictors of interindividual differences in response to DNA damaging agents.

Fry RC, Svensson JP, Valiathan C, Wang E, Hogan BJ, Bhattacharya S, Bugni JM, Whittaker CA, Samson LD.

Genes Dev. 2008 Oct 1;22(19):2621-6. doi: 10.1101/gad.1688508. Epub 2008 Sep 19.

35.

Loss of p53 synthesis in zebrafish tumors with ribosomal protein gene mutations.

MacInnes AW, Amsterdam A, Whittaker CA, Hopkins N, Lees JA.

Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10408-13. doi: 10.1073/pnas.0805036105. Epub 2008 Jul 18.

36.

Protein 4.1B suppresses prostate cancer progression and metastasis.

Wong SY, Haack H, Kissil JL, Barry M, Bronson RT, Shen SS, Whittaker CA, Crowley D, Hynes RO.

Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):12784-9. Epub 2007 Jul 18.

37.

The genome of the sea urchin Strongylocentrotus purpuratus.

Sea Urchin Genome Sequencing Consortium, Sodergren E, Weinstock GM, Davidson EH, Cameron RA, Gibbs RA, Angerer RC, Angerer LM, Arnone MI, Burgess DR, Burke RD, Coffman JA, Dean M, Elphick MR, Ettensohn CA, Foltz KR, Hamdoun A, Hynes RO, Klein WH, Marzluff W, McClay DR, Morris RL, Mushegian A, Rast JP, Smith LC, Thorndyke MC, Vacquier VD, Wessel GM, Wray G, Zhang L, Elsik CG, Ermolaeva O, Hlavina W, Hofmann G, Kitts P, Landrum MJ, Mackey AJ, Maglott D, Panopoulou G, Poustka AJ, Pruitt K, Sapojnikov V, Song X, Souvorov A, Solovyev V, Wei Z, Whittaker CA, Worley K, Durbin KJ, Shen Y, Fedrigo O, Garfield D, Haygood R, Primus A, Satija R, Severson T, Gonzalez-Garay ML, Jackson AR, Milosavljevic A, Tong M, Killian CE, Livingston BT, Wilt FH, Adams N, Bellé R, Carbonneau S, Cheung R, Cormier P, Cosson B, Croce J, Fernandez-Guerra A, Genevière AM, Goel M, Kelkar H, Morales J, Mulner-Lorillon O, Robertson AJ, Goldstone JV, Cole B, Epel D, Gold B, Hahn ME, Howard-Ashby M, Scally M, Stegeman JJ, Allgood EL, Cool J, Judkins KM, McCafferty SS, Musante AM, Obar RA, Rawson AP, Rossetti BJ, Gibbons IR, Hoffman MP, Leone A, Istrail S, Materna SC, Samanta MP, Stolc V, Tongprasit W, Tu Q, Bergeron KF, Brandhorst BP, Whittle J, Berney K, Bottjer DJ, Calestani C, Peterson K, Chow E, Yuan QA, Elhaik E, Graur D, Reese JT, Bosdet I, Heesun S, Marra MA, Schein J, Anderson MK, Brockton V, Buckley KM, Cohen AH, Fugmann SD, Hibino T, Loza-Coll M, Majeske AJ, Messier C, Nair SV, Pancer Z, Terwilliger DP, Agca C, Arboleda E, Chen N, Churcher AM, Hallböök F, Humphrey GW, Idris MM, Kiyama T, Liang S, Mellott D, Mu X, Murray G, Olinski RP, Raible F, Rowe M, Taylor JS, Tessmar-Raible K, Wang D, Wilson KH, Yaguchi S, Gaasterland T, Galindo BE, Gunaratne HJ, Juliano C, Kinukawa M, Moy GW, Neill AT, Nomura M, Raisch M, Reade A, Roux MM, Song JL, Su YH, Townley IK, Voronina E, Wong JL, Amore G, Branno M, Brown ER, Cavalieri V, Duboc V, Duloquin L, Flytzanis C, Gache C, Lapraz F, Lepage T, Locascio A, Martinez P, Matassi G, Matranga V, Range R, Rizzo F, Röttinger E, Beane W, Bradham C, Byrum C, Glenn T, Hussain S, Manning G, Miranda E, Thomason R, Walton K, Wikramanayke A, Wu SY, Xu R, Brown CT, Chen L, Gray RF, Lee PY, Nam J, Oliveri P, Smith J, Muzny D, Bell S, Chacko J, Cree A, Curry S, Davis C, Dinh H, Dugan-Rocha S, Fowler J, Gill R, Hamilton C, Hernandez J, Hines S, Hume J, Jackson L, Jolivet A, Kovar C, Lee S, Lewis L, Miner G, Morgan M, Nazareth LV, Okwuonu G, Parker D, Pu LL, Thorn R, Wright R.

Science. 2006 Nov 10;314(5801):941-52. Erratum in: Science. 2007 Feb 9;315(5813):766.

38.

The echinoderm adhesome.

Whittaker CA, Bergeron KF, Whittle J, Brandhorst BP, Burke RD, Hynes RO.

Dev Biol. 2006 Dec 1;300(1):252-66. Epub 2006 Aug 7.

39.

DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

Zody MC, Garber M, Adams DJ, Sharpe T, Harrow J, Lupski JR, Nicholson C, Searle SM, Wilming L, Young SK, Abouelleil A, Allen NR, Bi W, Bloom T, Borowsky ML, Bugalter BE, Butler J, Chang JL, Chen CK, Cook A, Corum B, Cuomo CA, de Jong PJ, DeCaprio D, Dewar K, FitzGerald M, Gilbert J, Gibson R, Gnerre S, Goldstein S, Grafham DV, Grocock R, Hafez N, Hagopian DS, Hart E, Norman CH, Humphray S, Jaffe DB, Jones M, Kamal M, Khodiyar VK, LaButti K, Laird G, Lehoczky J, Liu X, Lokyitsang T, Loveland J, Lui A, Macdonald P, Major JE, Matthews L, Mauceli E, McCarroll SA, Mihalev AH, Mudge J, Nguyen C, Nicol R, O'Leary SB, Osoegawa K, Schwartz DC, Shaw-Smith C, Stankiewicz P, Steward C, Swarbreck D, Venkataraman V, Whittaker CA, Yang X, Zimmer AR, Bradley A, Hubbard T, Birren BW, Rogers J, Lander ES, Nusbaum C.

Nature. 2006 Apr 20;440(7087):1045-9.

40.

Analysis of the DNA sequence and duplication history of human chromosome 15.

Zody MC, Garber M, Sharpe T, Young SK, Rowen L, O'Neill K, Whittaker CA, Kamal M, Chang JL, Cuomo CA, Dewar K, FitzGerald MG, Kodira CD, Madan A, Qin S, Yang X, Abbasi N, Abouelleil A, Arachchi HM, Baradarani L, Birditt B, Bloom S, Bloom T, Borowsky ML, Burke J, Butler J, Cook A, DeArellano K, DeCaprio D, Dorris L 3rd, Dors M, Eichler EE, Engels R, Fahey J, Fleetwood P, Friedman C, Gearin G, Hall JL, Hensley G, Johnson E, Jones C, Kamat A, Kaur A, Locke DP, Madan A, Munson G, Jaffe DB, Lui A, Macdonald P, Mauceli E, Naylor JW, Nesbitt R, Nicol R, O'Leary SB, Ratcliffe A, Rounsley S, She X, Sneddon KM, Stewart S, Sougnez C, Stone SM, Topham K, Vincent D, Wang S, Zimmer AR, Birren BW, Hood L, Lander ES, Nusbaum C.

Nature. 2006 Mar 30;440(7084):671-5.

PMID:
16572171
41.

DNA sequence and analysis of human chromosome 8.

Nusbaum C, Mikkelsen TS, Zody MC, Asakawa S, Taudien S, Garber M, Kodira CD, Schueler MG, Shimizu A, Whittaker CA, Chang JL, Cuomo CA, Dewar K, FitzGerald MG, Yang X, Allen NR, Anderson S, Asakawa T, Blechschmidt K, Bloom T, Borowsky ML, Butler J, Cook A, Corum B, DeArellano K, DeCaprio D, Dooley KT, Dorris L 3rd, Engels R, Glöckner G, Hafez N, Hagopian DS, Hall JL, Ishikawa SK, Jaffe DB, Kamat A, Kudoh J, Lehmann R, Lokitsang T, Macdonald P, Major JE, Matthews CD, Mauceli E, Menzel U, Mihalev AH, Minoshima S, Murayama Y, Naylor JW, Nicol R, Nguyen C, O'Leary SB, O'Neill K, Parker SC, Polley A, Raymond CK, Reichwald K, Rodriguez J, Sasaki T, Schilhabel M, Siddiqui R, Smith CL, Sneddon TP, Talamas JA, Tenzin P, Topham K, Venkataraman V, Wen G, Yamazaki S, Young SK, Zeng Q, Zimmer AR, Rosenthal A, Birren BW, Platzer M, Shimizu N, Lander ES.

Nature. 2006 Jan 19;439(7074):331-5.

PMID:
16421571
42.

DNA sequence and analysis of human chromosome 18.

Nusbaum C, Zody MC, Borowsky ML, Kamal M, Kodira CD, Taylor TD, Whittaker CA, Chang JL, Cuomo CA, Dewar K, FitzGerald MG, Yang X, Abouelleil A, Allen NR, Anderson S, Bloom T, Bugalter B, Butler J, Cook A, DeCaprio D, Engels R, Garber M, Gnirke A, Hafez N, Hall JL, Norman CH, Itoh T, Jaffe DB, Kuroki Y, Lehoczky J, Lui A, Macdonald P, Mauceli E, Mikkelsen TS, Naylor JW, Nicol R, Nguyen C, Noguchi H, O'Leary SB, O'Neill K, Piqani B, Smith CL, Talamas JA, Topham K, Totoki Y, Toyoda A, Wain HM, Young SK, Zeng Q, Zimmer AR, Fujiyama A, Hattori M, Birren BW, Sakaki Y, Lander ES.

Nature. 2005 Sep 22;437(7058):551-5. Erratum in: Nature. 2005 Dec 1;438(7068):696. O'Neill, Keith [added].

PMID:
16177791
43.

Cloning and characterization of chicken IL-10 and its role in the immune response to Eimeria maxima.

Rothwell L, Young JR, Zoorob R, Whittaker CA, Hesketh P, Archer A, Smith AL, Kaiser P.

J Immunol. 2004 Aug 15;173(4):2675-82.

45.

In vivo roles of integrins during leukocyte development and traffic: insights from the analysis of mice chimeric for alpha 5, alpha v, and alpha 4 integrins.

Arroyo AG, Taverna D, Whittaker CA, Strauch UG, Bader BL, Rayburn H, Crowley D, Parker CM, Hynes RO.

J Immunol. 2000 Oct 15;165(8):4667-75.

46.

Molecular cloning and developmental expression of the Xenopus homolog of integrin alpha 4.

Whittaker CA, Desimone DW.

Ann N Y Acad Sci. 1998 Oct 23;857:56-73.

PMID:
9917832
47.
48.

Cloning and characterization of cDNAs encoding the integrin alpha2 and alpha3 subunits from Xenopus laevis.

Meng F, Whittaker CA, Ransom DG, DeSimone DW.

Mech Dev. 1997 Oct;67(2):141-55.

49.

Integrin-dependent adhesive activity is spatially controlled by inductive signals at gastrulation.

Ramos JW, Whittaker CA, DeSimone DW.

Development. 1996 Sep;122(9):2873-83.

50.

Integrin alpha 6 expression is required for early nervous system development in Xenopus laevis.

Lallier TE, Whittaker CA, DeSimone DW.

Development. 1996 Aug;122(8):2539-54.

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