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Items: 22

1.

Prognostic Relevance of Steroid Sulfation in Adrenocortical Carcinoma Revealed by Molecular Phenotyping Using High-Resolution Mass Spectrometry Imaging.

Sun N, Kunzke T, Sbiera S, Kircher S, Feuchtinger A, Aichler M, Herterich S, Ronchi CL, Weigand I, Schlegel N, Waldmann J, Fragoso MCV, Whitsett TG, Gill AJ, Fassnacht M, Walch A, Kroiss M.

Clin Chem. 2019 Sep 6. pii: clinchem.2019.306043. doi: 10.1373/clinchem.2019.306043. [Epub ahead of print]

PMID:
31492715
2.

Identification of Recurrent Activating HER2 Mutations in Primary Canine Pulmonary Adenocarcinoma.

Lorch G, Sivaprakasam K, Zismann V, Perdigones N, Contente-Cuomo T, Nazareno A, Facista S, Wong S, Drenner K, Liang WS, Amann JM, Sinicropi-Yao SL, Koenig MJ, La Perle K, Whitsett TG, Murtaza M, Trent JM, Carbone DP, Hendricks WPD.

Clin Cancer Res. 2019 Aug 20. doi: 10.1158/1078-0432.CCR-19-1145. [Epub ahead of print]

PMID:
31431454
3.

LKB1 inactivation occurs in a subset of esophageal adenocarcinomas and is sufficient to drive tumor cell proliferation.

Whitsett TG, Mittal SK, Eschbacher JM, Carson VM, Smith MA, Bremner RM, Inge LJ.

J Thorac Cardiovasc Surg. 2018 Apr;155(4):1891-1899. doi: 10.1016/j.jtcvs.2017.11.067. Epub 2017 Dec 23.

PMID:
29370903
4.

Protein Expression of PTTG1 as a Diagnostic Biomarker in Adrenocortical Carcinoma.

Romero Arenas MA, Whitsett TG, Aronova A, Henderson SA, LoBello J, Habra MA, Grubbs EG, Lee JE, Sircar K, Zarnegar R, Scognamiglio T, Fahey TJ, Perrier ND, Demeure MJ.

Ann Surg Oncol. 2018 Mar;25(3):801-807. doi: 10.1245/s10434-017-6297-1. Epub 2017 Dec 7.

PMID:
29218429
5.

STMN1 is Overexpressed in Adrenocortical Carcinoma and Promotes a More Aggressive Phenotype In Vitro.

Aronova A, Min IM, Crowley MJP, Panjwani SJ, Finnerty BM, Scognamiglio T, Liu YF, Whitsett TG, Garg S, Demeure MJ, Elemento O, Zarnegar R, Fahey TJ III.

Ann Surg Oncol. 2018 Mar;25(3):792-800. doi: 10.1245/s10434-017-6296-2. Epub 2017 Dec 6.

PMID:
29214451
6.

WEE1 Kinase Inhibitor AZD1775 Has Preclinical Efficacy in LKB1-Deficient Non-Small Cell Lung Cancer.

Richer AL, Cala JM, O'Brien K, Carson VM, Inge LJ, Whitsett TG.

Cancer Res. 2017 Sep 1;77(17):4663-4672. doi: 10.1158/0008-5472.CAN-16-3565. Epub 2017 Jun 26.

7.

A prospective pilot study of genome-wide exome and transcriptome profiling in patients with small cell lung cancer progressing after first-line therapy.

Weiss GJ, Byron SA, Aldrich J, Sangal A, Barilla H, Kiefer JA, Carpten JD, Craig DW, Whitsett TG.

PLoS One. 2017 Jun 6;12(6):e0179170. doi: 10.1371/journal.pone.0179170. eCollection 2017.

8.

Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma.

Zheng S, Cherniack AD, Dewal N, Moffitt RA, Danilova L, Murray BA, Lerario AM, Else T, Knijnenburg TA, Ciriello G, Kim S, Assie G, Morozova O, Akbani R, Shih J, Hoadley KA, Choueiri TK, Waldmann J, Mete O, Robertson AG, Wu HT, Raphael BJ, Shao L, Meyerson M, Demeure MJ, Beuschlein F, Gill AJ, Sidhu SB, Almeida MQ, Fragoso MCBV, Cope LM, Kebebew E, Habra MA, Whitsett TG, Bussey KJ, Rainey WE, Asa SL, Bertherat J, Fassnacht M, Wheeler DA; Cancer Genome Atlas Research Network, Hammer GD, Giordano TJ, Verhaak RGW.

Cancer Cell. 2016 Aug 8;30(2):363. doi: 10.1016/j.ccell.2016.07.013. Epub 2016 Aug 8. No abstract available.

9.

Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma.

Zheng S, Cherniack AD, Dewal N, Moffitt RA, Danilova L, Murray BA, Lerario AM, Else T, Knijnenburg TA, Ciriello G, Kim S, Assie G, Morozova O, Akbani R, Shih J, Hoadley KA, Choueiri TK, Waldmann J, Mete O, Robertson AG, Wu HT, Raphael BJ, Shao L, Meyerson M, Demeure MJ, Beuschlein F, Gill AJ, Sidhu SB, Almeida MQ, Fragoso MCBV, Cope LM, Kebebew E, Habra MA, Whitsett TG, Bussey KJ, Rainey WE, Asa SL, Bertherat J, Fassnacht M, Wheeler DA; Cancer Genome Atlas Research Network, Hammer GD, Giordano TJ, Verhaak RGW.

Cancer Cell. 2016 May 9;29(5):723-736. doi: 10.1016/j.ccell.2016.04.002. Erratum in: Cancer Cell. 2016 Aug 8;30(2):363.

10.

Pathway Implications of Aberrant Global Methylation in Adrenocortical Cancer.

Legendre CR, Demeure MJ, Whitsett TG, Gooden GC, Bussey KJ, Jung S, Waibhav T, Kim S, Salhia B.

PLoS One. 2016 Mar 10;11(3):e0150629. doi: 10.1371/journal.pone.0150629. eCollection 2016.

11.

Genomic profiling toward precision medicine in non-small cell lung cancer: getting beyond EGFR.

Richer AL, Friel JM, Carson VM, Inge LJ, Whitsett TG.

Pharmgenomics Pers Med. 2015 Feb 20;8:63-79. doi: 10.2147/PGPM.S52845. eCollection 2015. Review.

12.

The TWEAK Receptor Fn14 Is an Src-Inducible Protein and a Positive Regulator of Src-Driven Cell Invasion.

Cheng E, Whitsett TG, Tran NL, Winkles JA.

Mol Cancer Res. 2015 Mar;13(3):575-83. doi: 10.1158/1541-7786.MCR-14-0411. Epub 2014 Nov 12.

13.

FN14 expression correlates with MET in NSCLC and promotes MET-driven cell invasion.

Whitsett TG, Fortin Ensign SP, Dhruv HD, Inge LJ, Kurywchak P, Wolf KK, LoBello J, Kingsley CB, Allen JW, Weiss GJ, Tran NL.

Clin Exp Metastasis. 2014 Aug;31(6):613-23. doi: 10.1007/s10585-014-9653-6. Epub 2014 Apr 8.

PMID:
24710956
14.

Current approaches to the treatment of metastatic brain tumours.

Owonikoko TK, Arbiser J, Zelnak A, Shu HK, Shim H, Robin AM, Kalkanis SN, Whitsett TG, Salhia B, Tran NL, Ryken T, Moore MK, Egan KM, Olson JJ.

Nat Rev Clin Oncol. 2014 Apr;11(4):203-22. doi: 10.1038/nrclinonc.2014.25. Epub 2014 Feb 25. Review.

15.

Mcl-1 mediates TWEAK/Fn14-induced non-small cell lung cancer survival and therapeutic response.

Whitsett TG, Mathews IT, Cardone MH, Lena RJ, Pierceall WE, Bittner M, Sima C, LoBello J, Weiss GJ, Tran NL.

Mol Cancer Res. 2014 Apr;12(4):550-9. doi: 10.1158/1541-7786.MCR-13-0458. Epub 2014 Jan 27.

16.

The use of quantitative proteomics towards biomarker discovery in lung squamous cell carcinoma.

Whitsett TG, Inge LJ, Tran NL.

Transl Lung Cancer Res. 2013 Dec;2(6):457-60. doi: 10.3978/j.issn.2218-6751.2013.10.17.

17.

CRL4A-FBXW5-mediated degradation of DLC1 Rho GTPase-activating protein tumor suppressor promotes non-small cell lung cancer cell growth.

Kim TY, Jackson S, Xiong Y, Whitsett TG, Lobello JR, Weiss GJ, Tran NL, Bang YJ, Der CJ.

Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):16868-73. doi: 10.1073/pnas.1306358110. Epub 2013 Sep 30.

18.

Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) promotes glioblastoma cell chemotaxis via Lyn activation.

Dhruv HD, Whitsett TG, Jameson NM, Patel F, Winkles JA, Berens ME, Tran NL.

Carcinogenesis. 2014 Jan;35(1):218-26. doi: 10.1093/carcin/bgt289. Epub 2013 Aug 23.

19.

Molecular determinants of lung cancer metastasis to the central nervous system.

Whitsett TG, Inge LJ, Dhruv HD, Cheung PY, Weiss GJ, Bremner RM, Winkles JA, Tran NL.

Transl Lung Cancer Res. 2013 Aug;2(4):273-83. doi: 10.3978/j.issn.2218-6751.2013.03.12. Review.

20.

New insights into the functional consequences of ephrin A3 mutations in non-small cell lung cancer.

Whitsett TG, Loftus JC, Winkles JA, Tran NL.

Transl Lung Cancer Res. 2013 Feb;2(1):3-5. doi: 10.3978/j.issn.2218-6751.2012.10.05. No abstract available.

21.

Elevated expression of Fn14 in non-small cell lung cancer correlates with activated EGFR and promotes tumor cell migration and invasion.

Whitsett TG, Cheng E, Inge L, Asrani K, Jameson NM, Hostetter G, Weiss GJ, Kingsley CB, Loftus JC, Bremner R, Tran NL, Winkles JA.

Am J Pathol. 2012 Jul;181(1):111-20. doi: 10.1016/j.ajpath.2012.03.026. Epub 2012 May 23. Erratum in: Am J Pathol. 2012 Nov;181(5):1889.

22.

Genistein and resveratrol: mammary cancer chemoprevention and mechanisms of action in the rat.

Whitsett TG Jr, Lamartiniere CA.

Expert Rev Anticancer Ther. 2006 Dec;6(12):1699-706. Review.

PMID:
17181483

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