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Items: 42


Ross River virus envelope glycans contribute to disease through activation of the host complement system.

Gunn BM, Jones JE, Shabman RS, Whitmore AC, Sarkar S, Blevins LK, Morrison TE, Heise MT.

Virology. 2018 Feb;515:250-260. doi: 10.1016/j.virol.2017.12.022. Epub 2018 Jan 8.


Bayesian Diallel Analysis Reveals Mx1-Dependent and Mx1-Independent Effects on Response to Influenza A Virus in Mice.

Maurizio PL, Ferris MT, Keele GR, Miller DR, Shaw GD, Whitmore AC, West A, Morrison CR, Noll KE, Plante KS, Cockrell AS, Threadgill DW, Pardo-Manuel de Villena F, Baric RS, Heise MT, Valdar W.

G3 (Bethesda). 2018 Feb 2;8(2):427-445. doi: 10.1534/g3.117.300438.


Disruption of the Opal Stop Codon Attenuates Chikungunya Virus-Induced Arthritis and Pathology.

Jones JE, Long KM, Whitmore AC, Sanders W, Thurlow LR, Brown JA, Morrison CR, Vincent H, Peck KM, Browning C, Moorman N, Lim JK, Heise MT.

MBio. 2017 Nov 14;8(6). pii: e01456-17. doi: 10.1128/mBio.01456-17.


γδ T Cells Play a Protective Role in Chikungunya Virus-Induced Disease.

Long KM, Ferris MT, Whitmore AC, Montgomery SA, Thurlow LR, McGee CE, Rodriguez CA, Lim JK, Heise MT.

J Virol. 2015 Oct 21;90(1):433-43. doi: 10.1128/JVI.02159-15. Print 2016 Jan 1.


Genome Wide Identification of SARS-CoV Susceptibility Loci Using the Collaborative Cross.

Gralinski LE, Ferris MT, Aylor DL, Whitmore AC, Green R, Frieman MB, Deming D, Menachery VD, Miller DR, Buus RJ, Bell TA, Churchill GA, Threadgill DW, Katze MG, McMillan L, Valdar W, Heise MT, Pardo-Manuel de Villena F, Baric RS.

PLoS Genet. 2015 Oct 9;11(10):e1005504. doi: 10.1371/journal.pgen.1005504. eCollection 2015 Oct.


A gnotobiotic mouse model demonstrates that dietary fiber protects against colorectal tumorigenesis in a microbiota- and butyrate-dependent manner.

Donohoe DR, Holley D, Collins LB, Montgomery SA, Whitmore AC, Hillhouse A, Curry KP, Renner SW, Greenwalt A, Ryan EP, Godfrey V, Heise MT, Threadgill DS, Han A, Swenberg JA, Threadgill DW, Bultman SJ.

Cancer Discov. 2014 Dec;4(12):1387-97. doi: 10.1158/2159-8290.CD-14-0501. Epub 2014 Sep 29.


Genomic profiling of collaborative cross founder mice infected with respiratory viruses reveals novel transcripts and infection-related strain-specific gene and isoform expression.

Xiong H, Morrison J, Ferris MT, Gralinski LE, Whitmore AC, Green R, Thomas MJ, Tisoncik-Go J, Schroth GP, Pardo-Manuel de Villena F, Baric RS, Heise MT, Peng X, Katze MG.

G3 (Bethesda). 2014 Jun 5;4(8):1429-44. doi: 10.1534/g3.114.011759.


Dendritic cell immunoreceptor regulates Chikungunya virus pathogenesis in mice.

Long KM, Whitmore AC, Ferris MT, Sempowski GD, McGee C, Trollinger B, Gunn B, Heise MT.

J Virol. 2013 May;87(10):5697-706. doi: 10.1128/JVI.01611-12. Epub 2013 Mar 13.


Modeling host genetic regulation of influenza pathogenesis in the collaborative cross.

Ferris MT, Aylor DL, Bottomly D, Whitmore AC, Aicher LD, Bell TA, Bradel-Tretheway B, Bryan JT, Buus RJ, Gralinski LE, Haagmans BL, McMillan L, Miller DR, Rosenzweig E, Valdar W, Wang J, Churchill GA, Threadgill DW, McWeeney SK, Katze MG, Pardo-Manuel de Villena F, Baric RS, Heise MT.

PLoS Pathog. 2013 Feb;9(2):e1003196. doi: 10.1371/journal.ppat.1003196. Epub 2013 Feb 28.


Myd88-dependent toll-like receptor 7 signaling mediates protection from severe Ross River virus-induced disease in mice.

Neighbours LM, Long K, Whitmore AC, Heise MT.

J Virol. 2012 Oct;86(19):10675-85. doi: 10.1128/JVI.00601-12. Epub 2012 Jul 25.


Mannose binding lectin is required for alphavirus-induced arthritis/myositis.

Gunn BM, Morrison TE, Whitmore AC, Blevins LK, Hueston L, Fraser RJ, Herrero LJ, Ramirez R, Smith PN, Mahalingam S, Heise MT.

PLoS Pathog. 2012;8(3):e1002586. doi: 10.1371/journal.ppat.1002586. Epub 2012 Mar 22.


The role of the blood-brain barrier during Venezuelan equine encephalitis virus infection.

Schäfer A, Brooke CB, Whitmore AC, Johnston RE.

J Virol. 2011 Oct;85(20):10682-90. doi: 10.1128/JVI.05032-11. Epub 2011 Aug 17.


A mouse model of chikungunya virus-induced musculoskeletal inflammatory disease: evidence of arthritis, tenosynovitis, myositis, and persistence.

Morrison TE, Oko L, Montgomery SA, Whitmore AC, Lotstein AR, Gunn BM, Elmore SA, Heise MT.

Am J Pathol. 2011 Jan;178(1):32-40. doi: 10.1016/j.ajpath.2010.11.018. Epub 2010 Dec 23.


T cells facilitate recovery from Venezuelan equine encephalitis virus-induced encephalomyelitis in the absence of antibody.

Brooke CB, Deming DJ, Whitmore AC, White LJ, Johnston RE.

J Virol. 2010 May;84(9):4556-68. doi: 10.1128/JVI.02545-09. Epub 2010 Feb 24.


Acute infection with venezuelan equine encephalitis virus replicon particles catalyzes a systemic antiviral state and protects from lethal virus challenge.

Konopka JL, Thompson JM, Whitmore AC, Webb DL, Johnston RE.

J Virol. 2009 Dec;83(23):12432-42. doi: 10.1128/JVI.00564-09. Epub 2009 Sep 30.


Venezuelan equine encephalitis virus disrupts STAT1 signaling by distinct mechanisms independent of host shutoff.

Simmons JD, White LJ, Morrison TE, Montgomery SA, Whitmore AC, Johnston RE, Heise MT.

J Virol. 2009 Oct;83(20):10571-81. doi: 10.1128/JVI.01041-09. Epub 2009 Aug 5.


Replicon particles of Venezuelan equine encephalitis virus as a reductionist murine model for encephalitis.

Schäfer A, Whitmore AC, Konopka JL, Johnston RE.

J Virol. 2009 May;83(9):4275-86. doi: 10.1128/JVI.02383-08. Epub 2009 Feb 18.


The contribution of type I interferon signaling to immunity induced by alphavirus replicon vaccines.

Thompson JM, Whitmore AC, Staats HF, Johnston R.

Vaccine. 2008 Sep 15;26(39):4998-5003. doi: 10.1016/j.vaccine.2008.07.011. Epub 2008 Jul 24.


Alphavirus replicon particles acting as adjuvants promote CD8+ T cell responses to co-delivered antigen.

Thompson JM, Whitmore AC, Staats HF, Johnston RE.

Vaccine. 2008 Aug 5;26(33):4267-75. doi: 10.1016/j.vaccine.2008.05.046. Epub 2008 Jun 9.


Nonmucosal alphavirus vaccination stimulates a mucosal inductive environment in the peripheral draining lymph node.

Thompson JM, Nicholson MG, Whitmore AC, Zamora M, West A, Iwasaki A, Staats HF, Johnston RE.

J Immunol. 2008 Jul 1;181(1):574-85.


Increased immunogenicity of a DNA-launched Venezuelan equine encephalitis virus-based replicon DNA vaccine.

Ljungberg K, Whitmore AC, Fluet ME, Moran TP, Shabman RS, Collier ML, Kraus AA, Thompson JM, Montefiori DC, Beard C, Johnston RE.

J Virol. 2007 Dec;81(24):13412-23. Epub 2007 Oct 3.


Effects of rapid antigen degradation and VEE glycoprotein specificity on immune responses induced by a VEE replicon vaccine.

Fluet ME, Whitmore AC, Moshkoff DA, Fu K, Tang Y, Collier ML, West A, Moore DT, Swanstrom R, Johnston RE, Davis NL.

Virology. 2008 Jan 5;370(1):22-32. Epub 2007 Sep 27.


An immunogenic and protective alphavirus replicon particle-based dengue vaccine overcomes maternal antibody interference in weanling mice.

White LJ, Parsons MM, Whitmore AC, Williams BM, de Silva A, Johnston RE.

J Virol. 2007 Oct;81(19):10329-39. Epub 2007 Jul 25.


Mucosal and systemic adjuvant activity of alphavirus replicon particles.

Thompson JM, Whitmore AC, Konopka JL, Collier ML, Richmond EM, Davis NL, Staats HF, Johnston RE.

Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3722-7. Epub 2006 Feb 27.


Characterization of Ross River virus tropism and virus-induced inflammation in a mouse model of viral arthritis and myositis.

Morrison TE, Whitmore AC, Shabman RS, Lidbury BA, Mahalingam S, Heise MT.

J Virol. 2006 Jan;80(2):737-49.


Rapid induction of splenic and peritoneal B-1a cells in adult mice by thymus-independent type-2 antigen.

Whitmore AC, Neely HR, Diz R, Flood PM.

J Immunol. 2004 Nov 1;173(9):5406-14.


Phenotype of B cells responding to the thymus-independent type-2 antigen polyvinyl pyrrolidinone.

Whitmore AC, Haughton G, Arnold LW.

Int Immunol. 1996 Apr;8(4):533-42.


B-1 cells are made, not born.

Haughton G, Arnold LW, Whitmore AC, Clarke SH.

Immunol Today. 1993 Feb;14(2):84-7; discussion 87-91. Review. No abstract available.


Isotype switching in CD5 B cells.

Whitmore AC, Haughton G, Arnold LW.

Ann N Y Acad Sci. 1992 May 4;651:143-51. Review. No abstract available.


Ig isotype switching in B lymphocytes. A method for estimating isotype switch frequency in cloned B cell lymphomas.

Whitmore AC, Prowse DM, Arnold LW, Haughton G.

Int Immunol. 1989;1(5):532-9.


Subline divergence within L.C. Strong's C3H and CBA inbred mouse strains. A review.

Whitmore AC, Whitmore SP.

Immunogenetics. 1985;21(5):407-28. Review. No abstract available.


Rous sarcoma virus-induced tumors in mice--I. Macrophage-mediated natural cytotoxicity.

Giovarelli M, Landolfo S, Whitmore AC, Forni G.

Eur J Cancer Clin Oncol. 1982 Mar;18(3):307-15.


Correlation of FAD-monooxygenase activity with corticosterone levels in inbred mice.

Padilla GM, Rauckman EJ, Whitmore AC, Rosen GM.

Life Sci. 1980 Dec 15;27(24):2401-4. No abstract available.


Effect of immunologic intervention on in vivo murine Rous sarcoma virus tumorigenesis.

Banks RA, Babcock GF, Whitmore AC, Haughton G.

J Natl Cancer Inst. 1979 Dec;63(6):1423-31. No abstract available.


Genetics, the immune response and oncogenesis.

Haughton G, Whitmore AC.

Transplant Rev. 1976;28:75-97. Review. No abstract available.


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