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Items: 47


Plasmid Negative Regulation of CPAF Expression Is Pgp4 Independent and Restricted to Invasive Chlamydia trachomatis Biovars.

Patton MJ, Chen CY, Yang C, McCorrister S, Grant C, Westmacott G, Yuan XY, Ochoa E, Fariss R, Whitmire WM, Carlson JH, Caldwell HD, McClarty G.

MBio. 2018 Jan 30;9(1). pii: e02164-17. doi: 10.1128/mBio.02164-17.


Infection of Hysterectomized Mice with Chlamydia muridarum and Chlamydia trachomatis.

Yang C, Whitmire WM, Sturdevant GL, Bock K, Moore I, Caldwell HD.

Infect Immun. 2017 Jun 20;85(7). pii: e00197-17. doi: 10.1128/IAI.00197-17. Print 2017 Jul.


Chlamydia trachomatis ChxR is a transcriptional regulator of virulence factors that function in in vivo host-pathogen interactions.

Yang C, Kari L, Sturdevant GL, Song L, Patton MJ, Couch CE, Ilgenfritz JM, Southern TR, Whitmire WM, Briones M, Bonner C, Grant C, Hu P, McClarty G, Caldwell HD.

Pathog Dis. 2017 Apr 1;75(3). doi: 10.1093/femspd/ftx035.


Chlamydial Lytic Exit from Host Cells Is Plasmid Regulated.

Yang C, Starr T, Song L, Carlson JH, Sturdevant GL, Beare PA, Whitmire WM, Caldwell HD.

MBio. 2015 Nov 10;6(6):e01648-15. doi: 10.1128/mBio.01648-15.


Transcriptional profiling of human epithelial cells infected with plasmid-bearing and plasmid-deficient Chlamydia trachomatis.

Porcella SF, Carlson JH, Sturdevant DE, Sturdevant GL, Kanakabandi K, Virtaneva K, Wilder H, Whitmire WM, Song L, Caldwell HD.

Infect Immun. 2015 Feb;83(2):534-43. doi: 10.1128/IAI.02764-14. Epub 2014 Nov 17.


Chlamydia trachomatis polymorphic membrane protein D is a virulence factor involved in early host-cell interactions.

Kari L, Southern TR, Downey CJ, Watkins HS, Randall LB, Taylor LD, Sturdevant GL, Whitmire WM, Caldwell HD.

Infect Immun. 2014 Jul;82(7):2756-62. doi: 10.1128/IAI.01686-14. Epub 2014 Apr 14.


CD8+ T cells define an unexpected role in live-attenuated vaccine protective immunity against Chlamydia trachomatis infection in macaques.

Olivares-Zavaleta N, Whitmire WM, Kari L, Sturdevant GL, Caldwell HD.

J Immunol. 2014 May 15;192(10):4648-54. doi: 10.4049/jimmunol.1400120. Epub 2014 Apr 7.


Infectivity of urogenital Chlamydia trachomatis plasmid-deficient, CT135-null, and double-deficient strains in female mice.

Sturdevant GL, Zhou B, Carlson JH, Whitmire WM, Song L, Caldwell HD.

Pathog Dis. 2014 Jun;71(1):90-2. doi: 10.1111/2049-632X.12121. Epub 2014 Jan 13.


Plasmid-mediated transformation tropism of chlamydial biovars.

Song L, Carlson JH, Zhou B, Virtaneva K, Whitmire WM, Sturdevant GL, Porcella SF, McClarty G, Caldwell HD.

Pathog Dis. 2014 Mar;70(2):189-93. doi: 10.1111/2049-632X.12104. Epub 2013 Nov 11.


Antibody signature of spontaneous clearance of Chlamydia trachomatis ocular infection and partial resistance against re-challenge in a nonhuman primate trachoma model.

Kari L, Bakios LE, Goheen MM, Bess LN, Watkins HS, Southern TR, Song L, Whitmire WM, Olivares-Zavaleta N, Caldwell HD.

PLoS Negl Trop Dis. 2013 May 30;7(5):e2248. doi: 10.1371/journal.pntd.0002248. Print 2013.


Chlamydia trachomatis plasmid-encoded Pgp4 is a transcriptional regulator of virulence-associated genes.

Song L, Carlson JH, Whitmire WM, Kari L, Virtaneva K, Sturdevant DE, Watkins H, Zhou B, Sturdevant GL, Porcella SF, McClarty G, Caldwell HD.

Infect Immun. 2013 Mar;81(3):636-44. doi: 10.1128/IAI.01305-12. Epub 2013 Jan 14.


A live-attenuated chlamydial vaccine protects against trachoma in nonhuman primates.

Kari L, Whitmire WM, Olivares-Zavaleta N, Goheen MM, Taylor LD, Carlson JH, Sturdevant GL, Lu C, Bakios LE, Randall LB, Parnell MJ, Zhong G, Caldwell HD.

J Exp Med. 2011 Oct 24;208(11):2217-23. doi: 10.1084/jem.20111266. Epub 2011 Oct 10.


Chlamydia pneumoniae inhibits activated human T lymphocyte proliferation by the induction of apoptotic and pyroptotic pathways.

Olivares-Zavaleta N, Carmody A, Messer R, Whitmire WM, Caldwell HD.

J Immunol. 2011 Jun 15;186(12):7120-6. doi: 10.4049/jimmunol.1100393. Epub 2011 May 4.


Generation of targeted Chlamydia trachomatis null mutants.

Kari L, Goheen MM, Randall LB, Taylor LD, Carlson JH, Whitmire WM, Virok D, Rajaram K, Endresz V, McClarty G, Nelson DE, Caldwell HD.

Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):7189-93. doi: 10.1073/pnas.1102229108. Epub 2011 Apr 11.


Murine Chlamydia trachomatis genital infection is unaltered by depletion of CD4+ T cells and diminished adaptive immunity.

Morrison SG, Farris CM, Sturdevant GL, Whitmire WM, Morrison RP.

J Infect Dis. 2011 Apr 15;203(8):1120-8. doi: 10.1093/infdis/jiq176. Epub 2011 Feb 14.


Alteration of growth factors and neuronal death in diabetic retinopathy: what we have learned so far.

Whitmire W, Al-Gayyar MM, Abdelsaid M, Yousufzai BK, El-Remessy AB.

Mol Vis. 2011 Jan 28;17:300-8. Review.


Frameshift mutations in a single novel virulence factor alter the in vivo pathogenicity of Chlamydia trachomatis for the female murine genital tract.

Sturdevant GL, Kari L, Gardner DJ, Olivares-Zavaleta N, Randall LB, Whitmire WM, Carlson JH, Goheen MM, Selleck EM, Martens C, Caldwell HD.

Infect Immun. 2010 Sep;78(9):3660-8. doi: 10.1128/IAI.00386-10. Epub 2010 Jun 14.


Biological characterization of Chlamydia trachomatis plasticity zone MACPF domain family protein CT153.

Taylor LD, Nelson DE, Dorward DW, Whitmire WM, Caldwell HD.

Infect Immun. 2010 Jun;78(6):2691-9. doi: 10.1128/IAI.01455-09. Epub 2010 Mar 29.


Immunization with the attenuated plasmidless Chlamydia trachomatis L2(25667R) strain provides partial protection in a murine model of female genitourinary tract infection.

Olivares-Zavaleta N, Whitmire W, Gardner D, Caldwell HD.

Vaccine. 2010 Feb 10;28(6):1454-62. doi: 10.1016/j.vaccine.2009.11.073. Epub 2009 Dec 8.


Chlamydia trachomatis native major outer membrane protein induces partial protection in nonhuman primates: implication for a trachoma transmission-blocking vaccine.

Kari L, Whitmire WM, Crane DD, Reveneau N, Carlson JH, Goheen MM, Peterson EM, Pal S, de la Maza LM, Caldwell HD.

J Immunol. 2009 Jun 15;182(12):8063-70. doi: 10.4049/jimmunol.0804375.


Chlamydia trachomatis polymorphic membrane protein D is an oligomeric autotransporter with a higher-order structure.

Swanson KA, Taylor LD, Frank SD, Sturdevant GL, Fischer ER, Carlson JH, Whitmire WM, Caldwell HD.

Infect Immun. 2009 Jan;77(1):508-16. doi: 10.1128/IAI.01173-08. Epub 2008 Nov 10.


Liquid-based fluorescence in situ hybridization assay for detection of ERBB2 gene amplification in patients with breast cancer.

Yeh CH, Whitmire WA 3rd, Albitar M.

Clin Chem. 2008 Nov;54(11):1831-9. doi: 10.1373/clinchem.2008.107607. Epub 2008 Sep 11.


The Chlamydia trachomatis plasmid is a transcriptional regulator of chromosomal genes and a virulence factor.

Carlson JH, Whitmire WM, Crane DD, Wicke L, Virtaneva K, Sturdevant DE, Kupko JJ 3rd, Porcella SF, Martinez-Orengo N, Heinzen RA, Kari L, Caldwell HD.

Infect Immun. 2008 Jun;76(6):2273-83. doi: 10.1128/IAI.00102-08. Epub 2008 Mar 17.


Pathogenic diversity among Chlamydia trachomatis ocular strains in nonhuman primates is affected by subtle genomic variations.

Kari L, Whitmire WM, Carlson JH, Crane DD, Reveneau N, Nelson DE, Mabey DC, Bailey RL, Holland MJ, McClarty G, Caldwell HD.

J Infect Dis. 2008 Feb 1;197(3):449-56. doi: 10.1086/525285.


Phenotypic rescue of Chlamydia trachomatis growth in IFN-gamma treated mouse cells by irradiated Chlamydia muridarum.

Nelson DE, Taylor LD, Shannon JG, Whitmire WM, Crane DD, McClarty G, Su H, Kari L, Caldwell HD.

Cell Microbiol. 2007 Sep;9(9):2289-98. Epub 2007 May 15.


In vitro susceptibility of Staphylococcus aureus to thrombin-induced platelet microbicidal protein-1 (tPMP-1) is influenced by cell membrane phospholipid composition and asymmetry.

Mukhopadhyay K, Whitmire W, Xiong YQ, Molden J, Jones T, Peschel A, Staubitz P, Adler-Moore J, McNamara PJ, Proctor RA, Yeaman MR, Bayer AS.

Microbiology. 2007 Apr;153(Pt 4):1187-97.


Chlamydial IFN-gamma immune evasion is linked to host infection tropism.

Nelson DE, Virok DP, Wood H, Roshick C, Johnson RM, Whitmire WM, Crane DD, Steele-Mortimer O, Kari L, McClarty G, Caldwell HD.

Proc Natl Acad Sci U S A. 2005 Jul 26;102(30):10658-63. Epub 2005 Jul 14.


Chlamydial infection induces pathobiotype-specific protein tyrosine phosphorylation in epithelial cells.

Virok DP, Nelson DE, Whitmire WM, Crane DD, Goheen MM, Caldwell HD.

Infect Immun. 2005 Apr;73(4):1939-46.


Isolation of Chlamydia pneumoniae clonal variants by a focus-forming assay.

Gieffers J, Belland RJ, Whitmire W, Ouellette S, Crane D, Maass M, Byrne GI, Caldwell HD.

Infect Immun. 2002 Oct;70(10):5827-34.


Chlamydia trachomatis cytotoxicity associated with complete and partial cytotoxin genes.

Belland RJ, Scidmore MA, Crane DD, Hogan DM, Whitmire W, McClarty G, Caldwell HD.

Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13984-9. Epub 2001 Nov 13.


A subset of Cowdria ruminantium genes important for immune recognition and protection.

Barbet AF, Whitmire WM, Kamper SM, Simbi BH, Ganta RR, Moreland AL, Mwangi DM, McGuire TC, Mahan SM.

Gene. 2001 Sep 19;275(2):287-98.


The effect of doxycycline treatment on the development of protective immunity in a murine model of chlamydial genital infection.

Su H, Morrison R, Messer R, Whitmire W, Hughes S, Caldwell HD.

J Infect Dis. 1999 Oct;180(4):1252-8.


Differential sensitivity of distinct Chlamydia trachomatis isolates to IFN-gamma-mediated inhibition.

Perry LL, Su H, Feilzer K, Messer R, Hughes S, Whitmire W, Caldwell HD.

J Immunol. 1999 Mar 15;162(6):3541-8.


Vaccination against chlamydial genital tract infection after immunization with dendritic cells pulsed ex vivo with nonviable Chlamydiae.

Su H, Messer R, Whitmire W, Fischer E, Portis JC, Caldwell HD.

J Exp Med. 1998 Sep 7;188(5):809-18.


In vitro murine lymphocyte blastogenic responses to Cryptosporidium parvum.

Whitmire WM, Harp JA.

J Parasitol. 1990 Jun;76(3):450-2.


Shedding of the immunodominant P20 surface antigen of Eimeria bovis sporozoites.

Speer CA, Whitmire WM.

Infect Immun. 1989 Mar;57(3):999-1001.


Immunity patterns during acute infection by Eimeria bovis.

Hughes HP, Whitmire WM, Speer CA.

J Parasitol. 1989 Feb;75(1):86-91.


Protein 20, an immunodominant surface antigen of Eimeria bovis.

Whitmire WM, Kyle JE, Speer CA.

Infect Immun. 1989 Jan;57(1):289-90.


In vitro cultivation of meronts of Sarcocystis cruzi.

Speer CA, Whitmire WM, Reduker DW, Dubey JP.

J Parasitol. 1986 Oct;72(5):677-83.


Lymphokine-induced inhibition of growth of Eimeria bovis and Eimeria papillata (Apicomplexa) in cultured bovine monocytes.

Speer CA, Reduker DW, Burgess DE, Whitmire WM, Splitter GA.

Infect Immun. 1985 Nov;50(2):566-71.


Effects of nylon wool purification on infectivity and antigenicity of Eimeria falciformis sporozoites and merozoites.

Larsen RA, Kyle JE, Whitmire WM, Speer CA.

J Parasitol. 1984 Aug;70(4):597-601. No abstract available.


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