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Items: 1 to 50 of 60

1.

The mTOR-S6 kinase pathway promotes stress granule assembly.

Sfakianos AP, Mellor LE, Pang YF, Kritsiligkou P, Needs H, Abou-Hamdan H, Désaubry L, Poulin GB, Ashe MP, Whitmarsh AJ.

Cell Death Differ. 2018 Nov;25(10):1766-1780. doi: 10.1038/s41418-018-0076-9. Epub 2018 Mar 9.

2.

Ribonucleoprotein bodies are phased in.

Sfakianos AP, Whitmarsh AJ, Ashe MP.

Biochem Soc Trans. 2016 Oct 15;44(5):1411-1416. Review.

PMID:
27911723
3.

Multisite phosphorylation by MAPK.

Whitmarsh AJ, Davis RJ.

Science. 2016 Oct 14;354(6309):179-180. No abstract available.

PMID:
27738159
4.

Mitochondrial Proteins Moonlighting in the Nucleus.

Monaghan RM, Whitmarsh AJ.

Trends Biochem Sci. 2015 Dec;40(12):728-735. doi: 10.1016/j.tibs.2015.10.003. Epub 2015 Oct 28. Review.

PMID:
26520802
5.

A nuclear sensor of mitochondrial function.

Monaghan RM, Poulin GB, Whitmarsh AJ.

Oncotarget. 2015 Jun 30;6(18):15746-7. No abstract available.

6.

A nuclear role for the respiratory enzyme CLK-1 in regulating mitochondrial stress responses and longevity.

Monaghan RM, Barnes RG, Fisher K, Andreou T, Rooney N, Poulin GB, Whitmarsh AJ.

Nat Cell Biol. 2015 Jun;17(6):782-92. doi: 10.1038/ncb3170. Epub 2015 May 11.

7.

A new role for an old enemy.

Monaghan RM, Whitmarsh AJ.

Elife. 2015 Feb 10;4:e06424. doi: 10.7554/eLife.06424.

8.

Targeting apoptosis signalling kinase-1 (ASK-1) does not prevent the development of neuropathy in streptozotocin-induced diabetic mice.

Newton VL, Ali S, Duddy G, Whitmarsh AJ, Gardiner NJ.

PLoS One. 2014 Oct 16;9(10):e107437. doi: 10.1371/journal.pone.0107437. eCollection 2014.

9.

Regulation of axon growth by the JIP1-AKT axis.

Dajas-Bailador F, Bantounas I, Jones EV, Whitmarsh AJ.

J Cell Sci. 2014 Jan 1;127(Pt 1):230-9. doi: 10.1242/jcs.137208. Epub 2013 Nov 6.

10.

A new regulator of caveolae signalling.

Whitmarsh AJ.

Elife. 2013 Sep 24;2:e01428. doi: 10.7554/eLife.01428.

11.

MAP kinase signalling cascades and transcriptional regulation.

Yang SH, Sharrocks AD, Whitmarsh AJ.

Gene. 2013 Jan 15;513(1):1-13. doi: 10.1016/j.gene.2012.10.033. Epub 2012 Nov 1. Review.

PMID:
23123731
12.

Casein kinase 2 sends extracellular signal-regulated kinase nuclear.

Whitmarsh AJ.

Mol Cell Biol. 2011 Sep;31(17):3512-4. doi: 10.1128/MCB.05916-11. Epub 2011 Jul 26. No abstract available.

13.

Docking interactions of the JNK scaffold protein WDR62.

Cohen-Katsenelson K, Wasserman T, Khateb S, Whitmarsh AJ, Aronheim A.

Biochem J. 2011 Nov 1;439(3):381-90. doi: 10.1042/BJ20110284.

14.

A central role for p38 MAPK in the early transcriptional response to stress.

Whitmarsh AJ.

BMC Biol. 2010 Apr 27;8:47. doi: 10.1186/1741-7007-8-47.

15.

JIP1 binding to RBP-Jk mediates cross-talk between the Notch1 and JIP1-JNK signaling pathway.

Kim MY, Ann EJ, Mo JS, Dajas-Bailador F, Seo MS, Hong JA, Jung J, Choi YH, Yoon JH, Kim SM, Choi EJ, Hoe HS, Whitmarsh AJ, Park HS.

Cell Death Differ. 2010 Nov;17(11):1728-38. doi: 10.1038/cdd.2010.50. Epub 2010 May 28.

16.

Mouse ACF7 and drosophila short stop modulate filopodia formation and microtubule organisation during neuronal growth.

Sanchez-Soriano N, Travis M, Dajas-Bailador F, Gonçalves-Pimentel C, Whitmarsh AJ, Prokop A.

J Cell Sci. 2009 Jul 15;122(Pt 14):2534-42. doi: 10.1242/jcs.046268.

17.

Filamin B: a scaffold for interferon signalling.

Whitmarsh AJ.

EMBO Rep. 2009 Apr;10(4):349-51. doi: 10.1038/embor.2009.44. Epub 2009 Mar 20. Review. No abstract available.

18.

Analyzing mitogen-activated protein kinase (MAPK) activities in T cells.

Whitmarsh AJ, Davis RJ.

Curr Protoc Immunol. 2004 Feb;Chapter 11:Unit 11.8. doi: 10.1002/0471142735.im1108s58. Review.

PMID:
18432922
19.

The beta-arrestin-2 scaffold protein promotes c-Jun N-terminal kinase-3 activation by binding to its nonconserved N terminus.

Guo C, Whitmarsh AJ.

J Biol Chem. 2008 Jun 6;283(23):15903-11. doi: 10.1074/jbc.M710006200. Epub 2008 Apr 11.

20.

The JIP1 scaffold protein regulates axonal development in cortical neurons.

Dajas-Bailador F, Jones EV, Whitmarsh AJ.

Curr Biol. 2008 Feb 12;18(3):221-6. doi: 10.1016/j.cub.2008.01.025.

21.

Regulation of p73-mediated apoptosis by c-Jun N-terminal kinase.

Jones EV, Dickman MJ, Whitmarsh AJ.

Biochem J. 2007 Aug 1;405(3):617-23.

22.

Role of mitogen-activated protein kinase kinase 4 in cancer.

Whitmarsh AJ, Davis RJ.

Oncogene. 2007 May 14;26(22):3172-84. Review.

PMID:
17496914
23.

Regulation of gene transcription by mitogen-activated protein kinase signaling pathways.

Whitmarsh AJ.

Biochim Biophys Acta. 2007 Aug;1773(8):1285-98. Epub 2006 Nov 17. Review.

24.

The JIP family of MAPK scaffold proteins.

Whitmarsh AJ.

Biochem Soc Trans. 2006 Nov;34(Pt 5):828-32.

PMID:
17052208
25.

Docking interactions in the c-Jun N-terminal kinase pathway.

Mooney LM, Whitmarsh AJ.

J Biol Chem. 2004 Mar 19;279(12):11843-52. Epub 2003 Dec 29.

26.

A critical role of neural-specific JNK3 for ischemic apoptosis.

Kuan CY, Whitmarsh AJ, Yang DD, Liao G, Schloemer AJ, Dong C, Bao J, Banasiak KJ, Haddad GG, Flavell RA, Davis RJ, Rakic P.

Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):15184-9. Epub 2003 Dec 1.

27.

Transcriptional regulation by the MAP kinase signaling cascades.

Yang SH, Sharrocks AD, Whitmarsh AJ.

Gene. 2003 Nov 27;320:3-21. Review.

PMID:
14597384
28.

The JNK-interacting protein-1 scaffold protein targets MAPK phosphatase-7 to dephosphorylate JNK.

Willoughby EA, Perkins GR, Collins MK, Whitmarsh AJ.

J Biol Chem. 2003 Mar 21;278(12):10731-6. Epub 2003 Jan 10.

29.

Examining signaling specificity to transcription factors.

Whitmarsh AJ.

Methods. 2002 Mar;26(3):217-25.

PMID:
12054877
30.

Signal transduction by MAP kinases: regulation by phosphorylation-dependent switches.

Whitmarsh AJ, Davis RJ.

Sci STKE. 1999 Sep 28;1999(1):PE1. Review.

PMID:
11865181
31.

Signal transduction by target-derived neurotrophins.

Whitmarsh AJ, Davis RJ.

Nat Neurosci. 2001 Oct;4(10):963-4. No abstract available.

PMID:
11574825
32.

Requirement of the JIP1 scaffold protein for stress-induced JNK activation.

Whitmarsh AJ, Kuan CY, Kennedy NJ, Kelkar N, Haydar TF, Mordes JP, Appel M, Rossini AA, Jones SN, Flavell RA, Rakic P, Davis RJ.

Genes Dev. 2001 Sep 15;15(18):2421-32.

33.

Analyzing JNK and p38 mitogen-activated protein kinase activity.

Whitmarsh AJ, Davis RJ.

Methods Enzymol. 2001;332:319-36. No abstract available.

PMID:
11305107
34.

Regulation of transcription factor function by phosphorylation.

Whitmarsh AJ, Davis RJ.

Cell Mol Life Sci. 2000 Aug;57(8-9):1172-83. Review.

PMID:
11028910
35.

JNK is required for effector T-cell function but not for T-cell activation.

Dong C, Yang DD, Tournier C, Whitmarsh AJ, Xu J, Davis RJ, Flavell RA.

Nature. 2000 May 4;405(6782):91-4.

PMID:
10811224
36.

A central control for cell growth.

Whitmarsh AJ, Davis RJ.

Nature. 2000 Jan 20;403(6767):255-6. No abstract available.

PMID:
10659830
37.

Regulation of c-Jun NH(2)-terminal kinase (Jnk) gene expression during T cell activation.

Weiss L, Whitmarsh AJ, Yang DD, Rincón M, Davis RJ, Flavell RA.

J Exp Med. 2000 Jan 3;191(1):139-46.

38.

The JIP group of mitogen-activated protein kinase scaffold proteins.

Yasuda J, Whitmarsh AJ, Cavanagh J, Sharma M, Davis RJ.

Mol Cell Biol. 1999 Oct;19(10):7245-54.

39.

c-Jun is a JNK-independent coactivator of the PU.1 transcription factor.

Behre G, Whitmarsh AJ, Coghlan MP, Hoang T, Carpenter CL, Zhang DE, Davis RJ, Tenen DG.

J Biol Chem. 1999 Feb 19;274(8):4939-46.

40.

Mechanism-based inhibition of C5-cytosine DNA methyltransferases by 2-H pyrimidinone.

Hurd PJ, Whitmarsh AJ, Baldwin GS, Kelly SM, Waltho JP, Price NC, Connolly BA, Hornby DP.

J Mol Biol. 1999 Feb 19;286(2):389-401.

PMID:
9973559
41.

The MKK7 gene encodes a group of c-Jun NH2-terminal kinase kinases.

Tournier C, Whitmarsh AJ, Cavanagh J, Barrett T, Davis RJ.

Mol Cell Biol. 1999 Feb;19(2):1569-81.

42.

Structural organization of MAP-kinase signaling modules by scaffold proteins in yeast and mammals.

Whitmarsh AJ, Davis RJ.

Trends Biochem Sci. 1998 Dec;23(12):481-5. Review.

PMID:
9868371
43.

Defective T cell differentiation in the absence of Jnk1.

Dong C, Yang DD, Wysk M, Whitmarsh AJ, Davis RJ, Flavell RA.

Science. 1998 Dec 11;282(5396):2092-5.

44.

Differentiation of CD4+ T cells to Th1 cells requires MAP kinase JNK2.

Yang DD, Conze D, Whitmarsh AJ, Barrett T, Davis RJ, Rincón M, Flavell RA.

Immunity. 1998 Oct;9(4):575-85.

45.

A mammalian scaffold complex that selectively mediates MAP kinase activation.

Whitmarsh AJ, Cavanagh J, Tournier C, Yasuda J, Davis RJ.

Science. 1998 Sep 11;281(5383):1671-4.

46.

Mechanism of sodium arsenite-mediated induction of heme oxygenase-1 in hepatoma cells. Role of mitogen-activated protein kinases.

Elbirt KK, Whitmarsh AJ, Davis RJ, Bonkovsky HL.

J Biol Chem. 1998 Apr 10;273(15):8922-31. Erratum in: J Biol Chem 1998 Jul 10;273(28):179.

47.

Differential targeting of MAP kinases to the ETS-domain transcription factor Elk-1.

Yang SH, Whitmarsh AJ, Davis RJ, Sharrocks AD.

EMBO J. 1998 Mar 16;17(6):1740-9.

48.

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene.

Yang DD, Kuan CY, Whitmarsh AJ, Rincón M, Zheng TS, Davis RJ, Rakic P, Flavell RA.

Nature. 1997 Oct 23;389(6653):865-70.

PMID:
9349820
49.

The Elk-1 ETS-domain transcription factor contains a mitogen-activated protein kinase targeting motif.

Yang SH, Yates PR, Whitmarsh AJ, Davis RJ, Sharrocks AD.

Mol Cell Biol. 1998 Feb;18(2):710-20.

50.

Phosphorylation of the oncogenic transcription factor interferon regulatory factor 2 (IRF2) in vitro and in vivo.

Birnbaum MJ, van Zundert B, Vaughan PS, Whitmarsh AJ, van Wijnen AJ, Davis RJ, Stein GS, Stein JL.

J Cell Biochem. 1997 Aug 1;66(2):175-83.

PMID:
9213219

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