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The authors reply.

Whitlock RH, Leslie WD, Tangri N.

Kidney Int. 2019 Jul;96(1):247-248. doi: 10.1016/j.kint.2019.03.011. No abstract available.


Elucidating Transmission Patterns of Endemic Mycobacterium avium subsp. paratuberculosis Using Molecular Epidemiology.

Mitchell RM, Beaver A, Knupfer E, Pradhan AK, Fyock T, Whitlock RH, Schukken YH.

Vet Sci. 2019 Mar 20;6(1). pii: E32. doi: 10.3390/vetsci6010032.


The Fracture Risk Assessment Tool (FRAX®) predicts fracture risk in patients with chronic kidney disease.

Whitlock RH, Leslie WD, Shaw J, Rigatto C, Thorlacius L, Komenda P, Collister D, Kanis JA, Tangri N.

Kidney Int. 2019 Feb;95(2):447-454. doi: 10.1016/j.kint.2018.09.022. Epub 2018 Dec 20.


Long term health outcomes in patients with a history of myocardial infarction: A population based cohort study.

Tangri N, Ferguson TW, Whitlock RH, Rigatto C, Jassal DS, Kass M, Toleva O, Komenda P.

PLoS One. 2017 Jul 12;12(7):e0180010. doi: 10.1371/journal.pone.0180010. eCollection 2017.


Validation of the Kidney Failure Risk Equation in Manitoba.

Whitlock RH, Chartier M, Komenda P, Hingwala J, Rigatto C, Walld R, Dart A, Tangri N.

Can J Kidney Health Dis. 2017 Apr 20;4:2054358117705372. doi: 10.1177/2054358117705372. eCollection 2017.


Impact of the shedding level on transmission of persistent infections in Mycobacterium avium subspecies paratuberculosis (MAP).

Slater N, Mitchell RM, Whitlock RH, Fyock T, Pradhan AK, Knupfer E, Schukken YH, Louzoun Y.

Vet Res. 2016 Feb 29;47:38. doi: 10.1186/s13567-016-0323-3.


The effects of progressing and nonprogressing Mycobacterium avium ssp. paratuberculosis infection on milk production in dairy cows.

Smith RL, Gröhn YT, Pradhan AK, Whitlock RH, Van Kessel JS, Smith JM, Wolfgang DR, Schukken YH.

J Dairy Sci. 2016 Feb;99(2):1383-1390. doi: 10.3168/jds.2015-9822. Epub 2015 Dec 10.


A before and after cross-sectional analysis of a public health campaign to increase kidney health awareness in a Canadian province.

Ryz K, Tangri N, Verrelli M, Schneider J, Lesyk A, Eng A, Hiebert B, Whitlock RH, Sood MM, Rigatto C, Komenda P.

BMC Res Notes. 2015 Nov 20;8:695. doi: 10.1186/s13104-015-1662-2.


Differences in intermittent and continuous fecal shedding patterns between natural and experimental Mycobacterium avium subspecies paratuberculosis infections in cattle.

Mitchell RM, Schukken Y, Koets A, Weber M, Bakker D, Stabel J, Whitlock RH, Louzoun Y.

Vet Res. 2015 Jun 19;46:66. doi: 10.1186/s13567-015-0188-x.


Longitudinal data collection of Mycobacterium avium subspecies Paratuberculosis infections in dairy herds: the value of precise field data.

Schukken YH, Whitlock RH, Wolfgang D, Grohn Y, Beaver A, VanKessel J, Zurakowski M, Mitchell R.

Vet Res. 2015 Jun 19;46:65. doi: 10.1186/s13567-015-0187-y.


Back to the real world: connecting models with data.

Mitchell RM, Whitlock RH, Gröhn YT, Schukken YH.

Prev Vet Med. 2015 Feb 1;118(2-3):215-25. doi: 10.1016/j.prevetmed.2014.12.009. Epub 2014 Dec 22.


Prevalence of Mycobacterium avium subsp. paratuberculosis fecal shedding in alpacas presented to veterinary hospitals in the United States.

Fecteau ME, Bedenice D, Cebra CK, Pinn TL, McAdams SC, Fyock TL, Whitlock RH, Sweeney RW.

J Vet Intern Med. 2013 Sep-Oct;27(5):1228-33. doi: 10.1111/jvim.12125. Epub 2013 Jun 19.


Cost-effectiveness of diagnostic strategies to identify Mycobacterium avium subspecies paratuberculosis super-shedder cows in a large dairy herd using antibody enzyme-linked immunosorbent assays, quantitative real-time polymerase chain reaction, and bacterial culture.

Aly SS, Anderson RJ, Whitlock RH, Fyock TL, McAdams SC, Byrem TM, Jiang J, Adaska JM, Gardner IA.

J Vet Diagn Invest. 2012 Sep;24(5):821-32. doi: 10.1177/1040638712452107. Epub 2012 Jul 17.


Quantitative real-time PCR for detection of the neurotoxin gene of Clostridium botulinum type B in equine and bovine samples.

Johnson AL, Sweeney RW, McAdams SC, Whitlock RH.

Vet J. 2012 Oct;194(1):118-20. doi: 10.1016/j.tvjl.2012.03.018. Epub 2012 Apr 24.


Meta-analysis of two genome-wide association studies of bovine paratuberculosis.

Minozzi G, Williams JL, Stella A, Strozzi F, Luini M, Settles ML, Taylor JF, Whitlock RH, Zanella R, Neibergs HL.

PLoS One. 2012;7(3):e32578. doi: 10.1371/journal.pone.0032578. Epub 2012 Mar 2.


Low rate of detectable in utero transmission of Mycobacterium avium subspecies paratuberculosis in a dairy herd with a low prevalence of Johne's disease.

Adaska JM, Whitlock RH.

J Vet Diagn Invest. 2012 Jan;24(1):153-5. doi: 10.1177/1040638711425947. Epub 2011 Dec 6.


Evolution of the bovine TLR gene family and member associations with Mycobacterium avium subspecies paratuberculosis infection.

Fisher CA, Bhattarai EK, Osterstock JB, Dowd SE, Seabury PM, Vikram M, Whitlock RH, Schukken YH, Schnabel RD, Taylor JF, Womack JE, Seabury CM.

PLoS One. 2011;6(11):e27744. doi: 10.1371/journal.pone.0027744. Epub 2011 Nov 30. Erratum in: PLoS One. 2012;7(1):doi/10.1371/annotation/429afd9a-2892-47ac-a403-008496b2e8db. PLoS One. 2012;7(1):doi/10.1371/annotation/63a06de9-db62-4651-87f3-a5fd431dcd80. PLoS One. 2012;7(2):doi/10.1371/annotation/a84f0490-55cd-4b42-8b2e-72661fabfc22.


Treatment and chemoprophylaxis for paratuberculosis.

Fecteau ME, Whitlock RH.

Vet Clin North Am Food Anim Pract. 2011 Nov;27(3):547-57, v. doi: 10.1016/j.cvfa.2011.07.002. Review.


Evaluation of the in vitro activity of gallium nitrate against Mycobacterium avium subsp paratuberculosis.

Fecteau ME, Fyock TL, McAdams SC, Boston RC, Whitlock RH, Sweeney RW.

Am J Vet Res. 2011 Sep;72(9):1243-6. doi: 10.2460/ajvr.72.9.1243.


Antimicrobial activity of gallium nitrate against Mycobacterium avium subsp. paratuberculosis in neonatal calves.

Fecteau ME, Whitlock RH, Fyock TL, McAdams SC, Boston RC, Sweeney RW.

J Vet Intern Med. 2011 Sep-Oct;25(5):1152-5. doi: 10.1111/j.1939-1676.2011.0768.x. Epub 2011 Jul 22.


Environmental contamination with Mycobacterium avium subsp. paratuberculosis in endemically infected dairy herds.

Smith RL, Schukken YH, Pradhan AK, Smith JM, Whitlock RH, Van Kessel JS, Wolfgang DR, Grohn YT.

Prev Vet Med. 2011 Oct 1;102(1):1-9. doi: 10.1016/j.prevetmed.2011.06.009. Epub 2011 Jul 19.


Culture phenotypes of genomically and geographically diverse Mycobacterium avium subsp. paratuberculosis isolates from different hosts.

Whittington RJ, Marsh IB, Saunders V, Grant IR, Juste R, Sevilla IA, Manning EJ, Whitlock RH.

J Clin Microbiol. 2011 May;49(5):1822-30. doi: 10.1128/JCM.00210-11. Epub 2011 Mar 23.


Application of a peptide-mediated magnetic separation-phage assay for detection of viable Mycobacterium avium subsp. paratuberculosis to bovine bulk tank milk and feces samples.

Foddai A, Strain S, Whitlock RH, Elliott CT, Grant IR.

J Clin Microbiol. 2011 May;49(5):2017-9. doi: 10.1128/JCM.00429-11. Epub 2011 Mar 16.


Molecular epidemiology of Mycobacterium avium subsp. paratuberculosis in a longitudinal study of three dairy herds.

Pradhan AK, Mitchell RM, Kramer AJ, Zurakowski MJ, Fyock TL, Whitlock RH, Smith JM, Hovingh E, Van Kessel JA, Karns JS, Schukken YH.

J Clin Microbiol. 2011 Mar;49(3):893-901. doi: 10.1128/JCM.01107-10. Epub 2011 Jan 5.


Development of a predictive model for detection of Mycobacterium avium subsp. paratuberculosis in faeces by quantitative real time PCR.

Kralik P, Slana I, Kralova A, Babak V, Whitlock RH, Pavlik I.

Vet Microbiol. 2011 Apr 21;149(1-2):133-8. doi: 10.1016/j.vetmic.2010.10.009. Epub 2010 Oct 21.


Correlation between Herrold egg yolk medium culture and real-time quantitative polymerase chain reaction results for Mycobacterium avium subspecies paratuberculosis in pooled fecal and environmental samples.

Aly SS, Mangold BL, Whitlock RH, Sweeney RW, Anderson RJ, Jiang J, Schukken YH, Hovingh E, Wolfgang D, Van Kessel JA, Karns JS, Lombard JE, Smith JM, Gardner IA.

J Vet Diagn Invest. 2010 Sep;22(5):677-83.


GSEA-SNP identifies genes associated with Johne's disease in cattle.

Neibergs HL, Settles ML, Whitlock RH, Taylor JF.

Mamm Genome. 2010 Aug;21(7-8):419-25. doi: 10.1007/s00335-010-9278-2. Epub 2010 Aug 13.


Absorbed EVELISA: a diagnostic test with improved specificity for Johne's disease in cattle.

Scott MC, Bannantine JP, Kaneko Y, Branscum AJ, Whitlock RH, Mori Y, Speer CA, Eda S.

Foodborne Pathog Dis. 2010 Nov;7(11):1291-6. doi: 10.1089/fpd.2010.0541. Epub 2010 Aug 12.


Effect of Johne's disease status on reproduction and culling in dairy cattle.

Smith RL, Strawderman RL, Schukken YH, Wells SJ, Pradhan AK, Espejo LA, Whitlock RH, Van Kessel JS, Smith JM, Wolfgang DR, Gröhn YT.

J Dairy Sci. 2010 Aug;93(8):3513-24. doi: 10.3168/jds.2009-2742.


Identification of loci associated with tolerance to Johne's disease in Holstein cattle.

Zanella R, Settles ML, McKay SD, Schnabel R, Taylor J, Whitlock RH, Schukken Y, Van Kessel JS, Smith JM, Neibergs HL.

Anim Genet. 2011 Feb;42(1):28-38. doi: 10.1111/j.1365-2052.2010.02076.x.


Type A botulism in horses in the United States: a review of the past ten years (1998-2008).

Johnson AL, McAdams SC, Whitlock RH.

J Vet Diagn Invest. 2010 Mar;22(2):165-73.


Mycobacterium avium ssp. paratuberculosis high shedding in an adult female alpaca, and its implications for the rest of the herd.

Fecteau ME, Ross J, Tennent-Brown BS, Habecker PL, Sreevatsan S, Sweeney RW, Whitlock RH.

J Vet Intern Med. 2009 Nov-Dec;23(6):1311-4. doi: 10.1111/j.1939-1676.2009.0401.x. No abstract available.


Reliability of environmental sampling to quantify Mycobacterium avium subspecies paratuberculosis on California free-stall dairies.

Aly SS, Anderson RJ, Whitlock RH, Fyock TL, McAdams S, Adaska JM, Jiang J, Gardner IA.

J Dairy Sci. 2009 Aug;92(8):3634-42. doi: 10.3168/jds.2008-1680.


A longitudinal study on the impact of Johne's disease status on milk production in individual cows.

Smith RL, Grohn YT, Pradhan AK, Whitlock RH, Van Kessel JS, Smith JM, Wolfgang DR, Schukken YH.

J Dairy Sci. 2009 Jun;92(6):2653-61. doi: 10.3168/jds.2008-1832.


Monensin causes dose dependent inhibition of Mycobacterium avium subspecies paratuberculosis in radiometric culture.

Greenstein RJ, Su L, Whitlock RH, Brown ST.

Gut Pathog. 2009 Feb 9;1(1):4. doi: 10.1186/1757-4749-1-4.


Effect of subcutaneous administration of a killed Mycobacterium avium subsp paratuberculosis vaccine on colonization of tissues following oral exposure to the organism in calves.

Sweeney RW, Whitlock RH, Bowersock TL, Cleary DL, Meinert TR, Habecker PL, Pruitt GW.

Am J Vet Res. 2009 Apr;70(4):493-7. doi: 10.2460/ajvr.70.4.493.


Dynamics of endemic infectious diseases of animal and human importance on three dairy herds in the northeastern United States.

Pradhan AK, Van Kessel JS, Karns JS, Wolfgang DR, Hovingh E, Nelen KA, Smith JM, Whitlock RH, Fyock T, Ladely S, Fedorka-Cray PJ, Schukken YH.

J Dairy Sci. 2009 Apr;92(4):1811-25. doi: 10.3168/jds.2008-1486.


Simulation modeling to evaluate the persistence of Mycobacterium avium subsp. paratuberculosis (MAP) on commercial dairy farms in the United States.

Mitchell RM, Whitlock RH, Stehman SM, Benedictus A, Chapagain PP, Grohn YT, Schukken YH.

Prev Vet Med. 2008 Mar 17;83(3-4):360-80. Epub 2007 Nov 26.


Transmission parameters of Mycobacterium avium subspecies paratuberculosis infections in a dairy herd going through a control program.

Benedictus A, Mitchell RM, Linde-Widmann M, Sweeney R, Fyock T, Schukken YH, Whitlock RH.

Prev Vet Med. 2008 Mar 17;83(3-4):215-27. Epub 2007 Sep 14.


Experimental challenge models for Johne's disease: a review and proposed international guidelines.

Hines ME 2nd, Stabel JR, Sweeney RW, Griffin F, Talaat AM, Bakker D, Benedictus G, Davis WC, de Lisle GW, Gardner IA, Juste RA, Kapur V, Koets A, McNair J, Pruitt G, Whitlock RH.

Vet Microbiol. 2007 Jun 21;122(3-4):197-222. Epub 2007 Mar 27. Review.


Evaluation of a rapid fecal PCR test for detection of Mycobacterium avium subsp. paratuberculosis in dairy cattle.

Wells SJ, Collins MT, Faaberg KS, Wees C, Tavornpanich S, Petrini KR, Collins JE, Cernicchiaro N, Whitlock RH.

Clin Vaccine Immunol. 2006 Oct;13(10):1125-30. Epub 2006 Aug 23.


A highly sensitive and subspecies-specific surface antigen enzyme- linked immunosorbent assay for diagnosis of Johne's disease.

Eda S, Bannantine JP, Waters WR, Mori Y, Whitlock RH, Scott MC, Speer CA.

Clin Vaccine Immunol. 2006 Aug;13(8):837-44.


A novel enzyme-linked immunosorbent assay for diagnosis of Mycobacterium avium subsp. paratuberculosis infections (Johne's Disease) in cattle.

Speer CA, Scott MC, Bannantine JP, Waters WR, Mori Y, Whitlock RH, Eda S.

Clin Vaccine Immunol. 2006 May;13(5):535-40.


Molecular typing of Mycobacterium avium subspecies paratuberculosis strains from different hosts and regions.

Sevilla Ix, Singh SV, Garrido JM, Aduriz G, Rodríguez S, Geijo MV, Whittington RJ, Saunders V, Whitlock RH, Juste RA.

Rev Sci Tech. 2005 Dec;24(3):1061-6. Review.


Tissue predilection sites and effect of dose on Mycobacterium avium subs. paratuberculosis organism recovery in a short-term bovine experimental oral infection model.

Sweeney RW, Uzonna J, Whitlock RH, Habecker PL, Chilton P, Scott P.

Res Vet Sci. 2006 Jun;80(3):253-9. Epub 2005 Sep 13.


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