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Items: 1 to 50 of 86

1.

Nonequivalent lethal equivalents: Models and inbreeding metrics for unbiased estimation of inbreeding load.

Nietlisbach P, Muff S, Reid JM, Whitlock MC, Keller LF.

Evol Appl. 2018 Oct 23;12(2):266-279. doi: 10.1111/eva.12713. eCollection 2019 Feb.

2.

Asymptomatic myocardial ischemia forecasts adverse events in cardiovascular magnetic resonance dobutamine stress testing of high-risk middle-aged and elderly individuals.

Stacey RB, Vera T, Morgan TM, Jordan JH, Whitlock MC, Hall ME, Vasu S, Hamilton C, Kitzman DW, Hundley WG.

J Cardiovasc Magn Reson. 2018 Nov 22;20(1):75. doi: 10.1186/s12968-018-0492-5.

3.

Quantifying how constraints limit the diversity of viable routes to adaptation.

Yeaman S, Gerstein AC, Hodgins KA, Whitlock MC.

PLoS Genet. 2018 Oct 8;14(10):e1007717. doi: 10.1371/journal.pgen.1007717. eCollection 2018 Oct.

4.

Environmental stress does not increase the mean strength of selection.

Arbuthnott D, Whitlock MC.

J Evol Biol. 2018 Oct;31(10):1599-1606. doi: 10.1111/jeb.13351. Epub 2018 Aug 1.

PMID:
29978525
5.

Bioinformatically predicted deleterious mutations reveal complementation in the interior spruce hybrid complex.

Conte GL, Hodgins KA, Yeaman S, Degner JC, Aitken SN, Rieseberg LH, Whitlock MC.

BMC Genomics. 2017 Dec 15;18(1):970. doi: 10.1186/s12864-017-4344-8.

6.

Local Adaptation Interacts with Expansion Load during Range Expansion: Maladaptation Reduces Expansion Load.

Gilbert KJ, Sharp NP, Angert AL, Conte GL, Draghi JA, Guillaume F, Hargreaves AL, Matthey-Doret R, Whitlock MC.

Am Nat. 2017 Apr;189(4):368-380. doi: 10.1086/690673. Epub 2017 Jan 27.

PMID:
28350500
7.

The genetics of adaptation to discrete heterogeneous environments: frequent mutation or large-effect alleles can allow range expansion.

Gilbert KJ, Whitlock MC.

J Evol Biol. 2017 Mar;30(3):591-602. doi: 10.1111/jeb.13029. Epub 2017 Jan 5.

8.

Convergent local adaptation to climate in distantly related conifers.

Yeaman S, Hodgins KA, Lotterhos KE, Suren H, Nadeau S, Degner JC, Nurkowski KA, Smets P, Wang T, Gray LK, Liepe KJ, Hamann A, Holliday JA, Whitlock MC, Rieseberg LH, Aitken SN.

Science. 2016 Sep 23;353(6306):1431-1433.

PMID:
27708038
9.

Finding the Genomic Basis of Local Adaptation: Pitfalls, Practical Solutions, and Future Directions.

Hoban S, Kelley JL, Lotterhos KE, Antolin MF, Bradburd G, Lowry DB, Poss ML, Reed LK, Storfer A, Whitlock MC.

Am Nat. 2016 Oct;188(4):379-97. doi: 10.1086/688018. Epub 2016 Aug 15. Review.

10.

Modern Approaches to Local Adaptation.

Whitlock MC.

Am Nat. 2015 Oct;186 Suppl 1:S1-4.

PMID:
27071207
11.

A Balanced Data Archiving Policy for Long-Term Studies.

Whitlock MC, Bronstein JL, Bruna EM, Ellison AM, Fox CW, McPeek MA, Moore AJ, Noor MAF, Rausher MD, Rieseberg LH, Ritchie MG, Shaw RG.

Trends Ecol Evol. 2016 Feb;31(2):84-85. doi: 10.1016/j.tree.2015.12.001. Epub 2015 Dec 17. No abstract available.

PMID:
26708957
12.

Reliable Detection of Loci Responsible for Local Adaptation: Inference of a Null Model through Trimming the Distribution of F(ST).

Whitlock MC, Lotterhos KE.

Am Nat. 2015 Oct;186 Suppl 1:S24-36. doi: 10.1086/682949. Epub 2015 Sep 15.

PMID:
26656214
13.

Cancer and Its Association With the Development of Coronary Artery Calcification: An Assessment From the Multi-Ethnic Study of Atherosclerosis.

Whitlock MC, Yeboah J, Burke GL, Chen H, Klepin HD, Hundley WG.

J Am Heart Assoc. 2015 Nov 9;4(11). pii: e002533. doi: 10.1161/JAHA.115.002533.

14.

Relation of Pre-anthracycline Serum Bilirubin Levels to Left Ventricular Ejection Fraction After Chemotherapy.

Vera T, D'Agostino RB Jr, Jordan JH, Whitlock MC, Meléndez GC, Lamar ZS, Porosnicu M, Bonkovsky HL, Poole LB, Hundley WG.

Am J Cardiol. 2015 Dec 1;116(11):1752-5. doi: 10.1016/j.amjcard.2015.08.042. Epub 2015 Sep 10.

15.

Noninvasive Imaging of Flow and Vascular Function in Disease of the Aorta.

Whitlock MC, Hundley WG.

JACC Cardiovasc Imaging. 2015 Sep;8(9):1094-1106. doi: 10.1016/j.jcmg.2015.08.001. Review.

16.

A clever solution to a vexing problem.

Whitlock MC.

Mol Ecol. 2015 Jul;24(14):3513-4. doi: 10.1111/mec.13280.

PMID:
26174126
17.

Evaluating methods for estimating local effective population size with and without migration.

Gilbert KJ, Whitlock MC.

Evolution. 2015 Aug;69(8):2154-66. doi: 10.1111/evo.12713. Epub 2015 Jul 21.

PMID:
26118738
18.

The relative power of genome scans to detect local adaptation depends on sampling design and statistical method.

Lotterhos KE, Whitlock MC.

Mol Ecol. 2015 Mar;24(5):1031-46. doi: 10.1111/mec.13100. Epub 2015 Feb 18.

PMID:
25648189
19.

Overdominance interacts with linkage to determine the rate of adaptation to a new optimum.

Draghi J, Whitlock MC.

J Evol Biol. 2015 Jan;28(1):95-104. doi: 10.1111/jeb.12547. Epub 2014 Dec 2.

20.

QST-FST comparisons with unbalanced half-sib designs.

Gilbert KJ, Whitlock MC.

Mol Ecol Resour. 2015 Mar;15(2):262-7. doi: 10.1111/1755-0998.12303. Epub 2014 Aug 8.

PMID:
25042150
21.

Evaluation of demographic history and neutral parameterization on the performance of FST outlier tests.

Lotterhos KE, Whitlock MC.

Mol Ecol. 2014 May;23(9):2178-92. doi: 10.1111/mec.12725. Epub 2014 Apr 11.

22.

Phenotypic plasticity facilitates mutational variance, genetic variance, and evolvability along the major axis of environmental variation.

Draghi JA, Whitlock MC.

Evolution. 2012 Sep;66(9):2891-902. doi: 10.1111/j.1558-5646.2012.01649.x. Epub 2012 May 1.

PMID:
22946810
23.

Experimental evolution.

Kawecki TJ, Lenski RE, Ebert D, Hollis B, Olivieri I, Whitlock MC.

Trends Ecol Evol. 2012 Oct;27(10):547-60. doi: 10.1016/j.tree.2012.06.001. Epub 2012 Jul 21. Review.

24.

Multilocus estimation of selfing and its heritability.

McClure NS, Whitlock MC.

Heredity (Edinb). 2012 Sep;109(3):173-9. doi: 10.1038/hdy.2012.27. Epub 2012 May 23.

25.

Q(ST) in a hierarchically structured population.

Whitlock MC, Gilbert KJ.

Mol Ecol Resour. 2012 May;12(3):481-3. doi: 10.1111/j.1755-0998.2012.03122.x. Epub 2012 Feb 16.

PMID:
22336101
26.

Dietary stress does not strengthen selection against single deleterious mutations in Drosophila melanogaster.

MacLellan K, Kwan L, Whitlock MC, Rundle HD.

Heredity (Edinb). 2012 Mar;108(3):203-10. doi: 10.1038/hdy.2011.60. Epub 2011 Jul 27.

27.

The genetic architecture of adaptation under migration-selection balance.

Yeaman S, Whitlock MC.

Evolution. 2011 Jul;65(7):1897-911. doi: 10.1111/j.1558-5646.2011.01269.x. Epub 2011 Mar 29.

PMID:
21729046
28.

Data archiving is a good investment.

Piwowar HA, Vision TJ, Whitlock MC.

Nature. 2011 May 19;473(7347):285. doi: 10.1038/473285a. No abstract available.

PMID:
21593852
29.

G'ST and D do not replace FST.

Whitlock MC.

Mol Ecol. 2011 Mar;20(6):1083-91. doi: 10.1111/j.1365-294X.2010.04996.x. Epub 2011 Jan 19.

PMID:
21375616
30.

Data archiving in ecology and evolution: best practices.

Whitlock MC.

Trends Ecol Evol. 2011 Feb;26(2):61-5. doi: 10.1016/j.tree.2010.11.006. Epub 2010 Dec 14.

PMID:
21159406
31.

Inferences about the distribution of dominance drawn from yeast gene knockout data.

Agrawal AF, Whitlock MC.

Genetics. 2011 Feb;187(2):553-66. doi: 10.1534/genetics.110.124560. Epub 2010 Nov 23.

32.

No effect of environmental heterogeneity on the maintenance of genetic variation in wing shape in Drosophila melanogaster.

Yeaman S, Chen Y, Whitlock MC.

Evolution. 2010 Dec;64(12):3398-408. doi: 10.1111/j.1558-5646.2010.01075.x.

PMID:
20624178
33.

Environmental duress and epistasis: how does stress affect the strength of selection on new mutations?

Agrawal AF, Whitlock MC.

Trends Ecol Evol. 2010 Aug;25(8):450-8. doi: 10.1016/j.tree.2010.05.003. Epub 2010 Jun 9. Review.

PMID:
20538366
34.

Local adaptation does not always predict high mating success.

Correia L, Yeaman S, Whitlock MC.

J Evol Biol. 2010 Apr;23(4):875-8. doi: 10.1111/j.1420-9101.2010.01957.x.

35.

The need for archiving data in evolutionary biology.

Moore AJ, McPeek MA, Rausher MD, Rieseberg L, Whitlock MC.

J Evol Biol. 2010 Apr;23(4):659-60. doi: 10.1111/j.1420-9101.2010.01937.x. Epub 2010 Feb 9. No abstract available.

36.

Data archiving.

Whitlock MC, McPeek MA, Rausher MD, Rieseberg L, Moore AJ.

Am Nat. 2010 Feb;175(2):145-6. doi: 10.1086/650340. No abstract available.

PMID:
20073990
37.

Data archiving.

Rausher MD, McPeek MA, Moore AJ, Rieseberg L, Whitlock MC.

Evolution. 2010 Mar 1;64(3):603-4. doi: 10.1111/j.1558-5646.2009.00940.x. Epub 2009 Dec 28. No abstract available.

PMID:
20050907
38.

The impact of epistatic selection on the genomic traces of selection.

Otto SP, Whitlock MC.

Mol Ecol. 2009 Dec;18(24):4985-7. doi: 10.1111/j.1365-294X.2009.04425.x.

PMID:
20025656
39.

Testing for spatially divergent selection: comparing QST to FST.

Whitlock MC, Guillaume F.

Genetics. 2009 Nov;183(3):1055-63. doi: 10.1534/genetics.108.099812. Epub 2009 Aug 17.

40.

Sexual selection against deleterious mutations via variable male search success.

Maclellan K, Whitlock MC, Rundle HD.

Biol Lett. 2009 Dec 23;5(6):795-7. doi: 10.1098/rsbl.2009.0475. Epub 2009 Jul 22. Erratum in: Biol Lett. 2010 Dec 23;6(6):862.

41.

Compensatory mutations are repeatable and clustered within proteins.

Davis BH, Poon AF, Whitlock MC.

Proc Biol Sci. 2009 May 22;276(1663):1823-7. doi: 10.1098/rspb.2008.1846. Epub 2009 Feb 25.

42.

Purging the genome with sexual selection: reducing mutation load through selection on males.

Whitlock MC, Agrawal AF.

Evolution. 2009 Mar;63(3):569-82. doi: 10.1111/j.1558-5646.2008.00558.x. Epub 2008 Dec 12. Review.

PMID:
19154364
43.

Evolutionary inference from QST.

Whitlock MC.

Mol Ecol. 2008 Apr;17(8):1885-96. doi: 10.1111/j.1365-294X.2008.03712.x. Epub 2008 Mar 17. Review.

PMID:
18363667
44.

The costs and benefits of resource sharing: reciprocity requires resource heterogeneity.

Whitlock MC, Davis BH, Yeaman S.

J Evol Biol. 2007 Sep;20(5):1772-82.

45.

Effects of migration on the genetic covariance matrix.

Guillaume F, Whitlock MC.

Evolution. 2007 Oct;61(10):2398-409. Epub 2007 Aug 17.

PMID:
17711463
46.

Male Drosophila melanogaster have higher mating success when adapted to their thermal environment.

Dolgin ES, Whitlock MC, Agrawal AF.

J Evol Biol. 2006 Nov;19(6):1894-900.

47.

Comment on "Ongoing adaptive evolution of ASPM, a brain size determinant in Homo sapiens" and "Microcephalin, a gene regulating brain size, continues to evolve adaptively in humans".

Currat M, Excoffier L, Maddison W, Otto SP, Ray N, Whitlock MC, Yeaman S.

Science. 2006 Jul 14;313(5784):172; author reply 172.

48.
49.

Probability of fixation in a heterogeneous environment.

Whitlock MC, Gomulkiewicz R.

Genetics. 2005 Nov;171(3):1407-17. Epub 2005 Aug 22.

50.

The incomplete natural history of mitochondria.

Ballard JW, Whitlock MC.

Mol Ecol. 2004 Apr;13(4):729-44. Review.

PMID:
15012752

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