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Items: 1 to 50 of 146

1.

British Society for Rheumatology guideline on diagnosis and treatment of giant cell arteritis: executive summary.

Mackie SL, Dejaco C, Appenzeller S, Camellino D, Duftner C, Gonzalez-Chiappe S, Mahr A, Mukhtyar C, Reynolds G, de Souza AWS, Brouwer E, Bukhari M, Buttgereit F, Byrne D, Cid MC, Cimmino M, Direskeneli H, Gilbert K, Kermani TA, Khan A, Lanyon P, Luqmani R, Mallen C, Mason JC, Matteson EL, Merkel PA, Mollan S, Neill L, Sullivan EO, Sandovici M, Schmidt WA, Watts R, Whitlock M, Yacyshyn E, Ytterberg S, Dasgupta B.

Rheumatology (Oxford). 2020 Mar 1;59(3):487-494. doi: 10.1093/rheumatology/kez664. No abstract available.

PMID:
31970410
2.

British Society for Rheumatology guideline on diagnosis and treatment of giant cell arteritis.

Mackie SL, Dejaco C, Appenzeller S, Camellino D, Duftner C, Gonzalez-Chiappe S, Mahr A, Mukhtyar C, Reynolds G, de Souza AWS, Brouwer E, Bukhari M, Buttgereit F, Byrne D, Cid MC, Cimmino M, Direskeneli H, Gilbert K, Kermani TA, Khan A, Lanyon P, Luqmani R, Mallen C, Mason JC, Matteson EL, Merkel PA, Mollan S, Neill L, Sullivan EO, Sandovici M, Schmidt WA, Watts R, Whitlock M, Yacyshyn E, Ytterberg S, Dasgupta B.

Rheumatology (Oxford). 2020 Mar 1;59(3):e1-e23. doi: 10.1093/rheumatology/kez672. No abstract available.

PMID:
31970405
3.

Is High Placebo Response Really a Problem in Depression Trials? A Critical Re-analysis of Depression Studies.

Whitlock ME, Woodward PW, Alexander RC.

Innov Clin Neurosci. 2019 Jul 1;16(7-08):12-17. eCollection 2019 Jul-Aug.

4.

No evidence of positive assortative mating for genetic quality in fruit flies.

Sharp NP, Whitlock MC.

Proc Biol Sci. 2019 Oct 9;286(1912):20191474. doi: 10.1098/rspb.2019.1474. Epub 2019 Oct 2.

PMID:
31575372
5.

Designing for Mobile and Immersive Visual Analytics in the Field.

Whitlock M, Wu K, Szafir DA.

IEEE Trans Vis Comput Graph. 2020 Jan;26(1):503-513. doi: 10.1109/TVCG.2019.2934282. Epub 2019 Aug 19.

PMID:
31425088
6.

Background selection and FST : Consequences for detecting local adaptation.

Matthey-Doret R, Whitlock MC.

Mol Ecol. 2019 Sep;28(17):3902-3914. doi: 10.1111/mec.15197. Epub 2019 Sep 3.

PMID:
31349365
7.

Response to "Treating patients rather than their functional neuroimages" (Br J Anaesth 2018; 121: 969-71).

Wanigasekera V, Wartolowska K, Huggins JP, Duff EP, Vennart W, Whitlock M, Massat N, Pauer L, Rogers P, Hoggart B, Tracey I.

Br J Anaesth. 2019 Aug;123(2):e166-e171. doi: 10.1016/j.bja.2019.01.016. Epub 2019 Apr 9. No abstract available.

8.

Analgesic potential of PF-06372865, an α2/α3/α5 subtype-selective GABAA partial agonist, in humans.

van Amerongen G, Siebenga PS, Gurrell R, Dua P, Whitlock M, Gorman D, Okkerse P, Hay JL, Butt RP, Groeneveld GJ.

Br J Anaesth. 2019 Aug;123(2):e194-e203. doi: 10.1016/j.bja.2018.12.006. Epub 2019 Jan 31.

9.

Photosensitive epilepsy: Robust clinical efficacy of a selective GABA potentiator.

Gurrell R, Gorman D, Whitlock M, Ogden A, Reynolds DS, DiVentura B, Abou-Khalil B, Gelfand M, Pollard J, Hogan RE, Krauss G, Sperling M, Vazquez B, Wechsler RT, Friedman D, Butt RP, French J.

Neurology. 2019 Apr 9;92(15):e1786-e1795. doi: 10.1212/WNL.0000000000007271. Epub 2019 Mar 15.

PMID:
30877186
10.

Nonequivalent lethal equivalents: Models and inbreeding metrics for unbiased estimation of inbreeding load.

Nietlisbach P, Muff S, Reid JM, Whitlock MC, Keller LF.

Evol Appl. 2018 Oct 23;12(2):266-279. doi: 10.1111/eva.12713. eCollection 2019 Feb.

12.

Asymptomatic myocardial ischemia forecasts adverse events in cardiovascular magnetic resonance dobutamine stress testing of high-risk middle-aged and elderly individuals.

Stacey RB, Vera T, Morgan TM, Jordan JH, Whitlock MC, Hall ME, Vasu S, Hamilton C, Kitzman DW, Hundley WG.

J Cardiovasc Magn Reson. 2018 Nov 22;20(1):75. doi: 10.1186/s12968-018-0492-5.

13.

Quantifying how constraints limit the diversity of viable routes to adaptation.

Yeaman S, Gerstein AC, Hodgins KA, Whitlock MC.

PLoS Genet. 2018 Oct 8;14(10):e1007717. doi: 10.1371/journal.pgen.1007717. eCollection 2018 Oct.

14.

Environmental stress does not increase the mean strength of selection.

Arbuthnott D, Whitlock MC.

J Evol Biol. 2018 Oct;31(10):1599-1606. doi: 10.1111/jeb.13351. Epub 2018 Aug 1.

PMID:
29978525
15.

A randomised, placebo-controlled clinical trial with the α2/3/5 subunit selective GABAA positive allosteric modulator PF-06372865 in patients with chronic low back pain.

Gurrell R, Dua P, Feng G, Sudworth M, Whitlock M, Reynolds DS, Butt RP.

Pain. 2018 Sep;159(9):1742-1751. doi: 10.1097/j.pain.0000000000001267.

PMID:
29787472
16.

Audio Recording for Independent Confirmation of Clinical Assessments in Generalized Anxiety Disorder.

Targum SD, Murphy C, Khan J, Zumpano L, Whitlock M, Simen AA, Binneman B.

Innov Clin Neurosci. 2018 Apr 1;15(3-4):37-42.

17.

Phase 1 clinical study of an embryonic stem cell-derived retinal pigment epithelium patch in age-related macular degeneration.

da Cruz L, Fynes K, Georgiadis O, Kerby J, Luo YH, Ahmado A, Vernon A, Daniels JT, Nommiste B, Hasan SM, Gooljar SB, Carr AF, Vugler A, Ramsden CM, Bictash M, Fenster M, Steer J, Harbinson T, Wilbrey A, Tufail A, Feng G, Whitlock M, Robson AG, Holder GE, Sagoo MS, Loudon PT, Whiting P, Coffey PJ.

Nat Biotechnol. 2018 Apr;36(4):328-337. doi: 10.1038/nbt.4114. Epub 2018 Mar 19.

PMID:
29553577
18.

The safety of Lipistart, a medium-chain triglyceride based formula, in the dietary treatment of long-chain fatty acid disorders: a phase I study.

MacDonald A, Webster R, Whitlock M, Gerrard A, Daly A, Preece MA, Evans S, Ashmore C, Chakrapani A, Vijay S, Santra S.

J Pediatr Endocrinol Metab. 2018 Mar 28;31(3):297-304. doi: 10.1515/jpem-2017-0426.

PMID:
29425111
19.

Disambiguating pharmacological mechanisms from placebo in neuropathic pain using functional neuroimaging.

Wanigasekera V, Wartolowska K, Huggins JP, Duff EP, Vennart W, Whitlock M, Massat N, Pauer L, Rogers P, Hoggart B, Tracey I.

Br J Anaesth. 2018 Feb;120(2):299-307. doi: 10.1016/j.bja.2017.11.064. Epub 2017 Nov 21.

20.

EULAR recommendations for the use of imaging in large vessel vasculitis in clinical practice.

Dejaco C, Ramiro S, Duftner C, Besson FL, Bley TA, Blockmans D, Brouwer E, Cimmino MA, Clark E, Dasgupta B, Diamantopoulos AP, Direskeneli H, Iagnocco A, Klink T, Neill L, Ponte C, Salvarani C, Slart RHJA, Whitlock M, Schmidt WA.

Ann Rheum Dis. 2018 May;77(5):636-643. doi: 10.1136/annrheumdis-2017-212649. Epub 2018 Jan 22.

21.

Bioinformatically predicted deleterious mutations reveal complementation in the interior spruce hybrid complex.

Conte GL, Hodgins KA, Yeaman S, Degner JC, Aitken SN, Rieseberg LH, Whitlock MC.

BMC Genomics. 2017 Dec 15;18(1):970. doi: 10.1186/s12864-017-4344-8.

22.

Pharmacology in translation: the preclinical and early clinical profile of the novel α2/3 functionally selective GABAA receptor positive allosteric modulator PF-06372865.

Nickolls SA, Gurrell R, van Amerongen G, Kammonen J, Cao L, Brown AR, Stead C, Mead A, Watson C, Hsu C, Owen RM, Pike A, Fish RL, Chen L, Qiu R, Morris ED, Feng G, Whitlock M, Gorman D, van Gerven J, Reynolds DS, Dua P, Butt RP.

Br J Pharmacol. 2018 Feb;175(4):708-725. doi: 10.1111/bph.14119. Epub 2018 Jan 18. Erratum in: Br J Pharmacol. 2019 Jan;176(1):127.

23.

Unlocking Endosomal Entrapment with Supercharged Arginine-Rich Peptides.

Najjar K, Erazo-Oliveras A, Mosior JW, Whitlock MJ, Rostane I, Cinclair JM, Pellois JP.

Bioconjug Chem. 2017 Dec 20;28(12):2932-2941. doi: 10.1021/acs.bioconjchem.7b00560. Epub 2017 Nov 13.

24.

Local Adaptation Interacts with Expansion Load during Range Expansion: Maladaptation Reduces Expansion Load.

Gilbert KJ, Sharp NP, Angert AL, Conte GL, Draghi JA, Guillaume F, Hargreaves AL, Matthey-Doret R, Whitlock MC.

Am Nat. 2017 Apr;189(4):368-380. doi: 10.1086/690673. Epub 2017 Jan 27.

PMID:
28350500
25.

The genetics of adaptation to discrete heterogeneous environments: frequent mutation or large-effect alleles can allow range expansion.

Gilbert KJ, Whitlock MC.

J Evol Biol. 2017 Mar;30(3):591-602. doi: 10.1111/jeb.13029. Epub 2017 Jan 5.

26.

Convergent local adaptation to climate in distantly related conifers.

Yeaman S, Hodgins KA, Lotterhos KE, Suren H, Nadeau S, Degner JC, Nurkowski KA, Smets P, Wang T, Gray LK, Liepe KJ, Hamann A, Holliday JA, Whitlock MC, Rieseberg LH, Aitken SN.

Science. 2016 Sep 23;353(6306):1431-1433.

PMID:
27708038
27.

Finding the Genomic Basis of Local Adaptation: Pitfalls, Practical Solutions, and Future Directions.

Hoban S, Kelley JL, Lotterhos KE, Antolin MF, Bradburd G, Lowry DB, Poss ML, Reed LK, Storfer A, Whitlock MC.

Am Nat. 2016 Oct;188(4):379-97. doi: 10.1086/688018. Epub 2016 Aug 15. Review.

28.

Modern Approaches to Local Adaptation.

Whitlock MC.

Am Nat. 2015 Oct;186 Suppl 1:S1-4.

PMID:
27071207
29.

A Balanced Data Archiving Policy for Long-Term Studies.

Whitlock MC, Bronstein JL, Bruna EM, Ellison AM, Fox CW, McPeek MA, Moore AJ, Noor MAF, Rausher MD, Rieseberg LH, Ritchie MG, Shaw RG.

Trends Ecol Evol. 2016 Feb;31(2):84-85. doi: 10.1016/j.tree.2015.12.001. Epub 2015 Dec 17. No abstract available.

PMID:
26708957
30.

Reliable Detection of Loci Responsible for Local Adaptation: Inference of a Null Model through Trimming the Distribution of F(ST).

Whitlock MC, Lotterhos KE.

Am Nat. 2015 Oct;186 Suppl 1:S24-36. doi: 10.1086/682949. Epub 2015 Sep 15.

PMID:
26656214
31.

Cancer and Its Association With the Development of Coronary Artery Calcification: An Assessment From the Multi-Ethnic Study of Atherosclerosis.

Whitlock MC, Yeboah J, Burke GL, Chen H, Klepin HD, Hundley WG.

J Am Heart Assoc. 2015 Nov 9;4(11). pii: e002533. doi: 10.1161/JAHA.115.002533.

32.

Relation of Pre-anthracycline Serum Bilirubin Levels to Left Ventricular Ejection Fraction After Chemotherapy.

Vera T, D'Agostino RB Jr, Jordan JH, Whitlock MC, Meléndez GC, Lamar ZS, Porosnicu M, Bonkovsky HL, Poole LB, Hundley WG.

Am J Cardiol. 2015 Dec 1;116(11):1752-5. doi: 10.1016/j.amjcard.2015.08.042. Epub 2015 Sep 10.

33.

Noninvasive Imaging of Flow and Vascular Function in Disease of the Aorta.

Whitlock MC, Hundley WG.

JACC Cardiovasc Imaging. 2015 Sep;8(9):1094-1106. doi: 10.1016/j.jcmg.2015.08.001. Review.

34.

2015 Recommendations for the management of polymyalgia rheumatica: a European League Against Rheumatism/American College of Rheumatology collaborative initiative.

Dejaco C, Singh YP, Perel P, Hutchings A, Camellino D, Mackie S, Abril A, Bachta A, Balint P, Barraclough K, Bianconi L, Buttgereit F, Carsons S, Ching D, Cid M, Cimmino M, Diamantopoulos A, Docken W, Duftner C, Fashanu B, Gilbert K, Hildreth P, Hollywood J, Jayne D, Lima M, Maharaj A, Mallen C, Martinez-Taboada V, Maz M, Merry S, Miller J, Mori S, Neill L, Nordborg E, Nott J, Padbury H, Pease C, Salvarani C, Schirmer M, Schmidt W, Spiera R, Tronnier D, Wagner A, Whitlock M, Matteson EL, Dasgupta B; European League Against Rheumatism; American College of Rheumatology.

Ann Rheum Dis. 2015 Oct;74(10):1799-807. doi: 10.1136/annrheumdis-2015-207492.

35.

2015 recommendations for the management of polymyalgia rheumatica: a European League Against Rheumatism/American College of Rheumatology collaborative initiative.

Dejaco C, Singh YP, Perel P, Hutchings A, Camellino D, Mackie S, Abril A, Bachta A, Balint P, Barraclough K, Bianconi L, Buttgereit F, Carsons S, Ching D, Cid M, Cimmino M, Diamantopoulos A, Docken W, Duftner C, Fashanu B, Gilbert K, Hildreth P, Hollywood J, Jayne D, Lima M, Maharaj A, Mallen C, Martinez-Taboada V, Maz M, Merry S, Miller J, Mori S, Neill L, Nordborg E, Nott J, Padbury H, Pease C, Salvarani C, Schirmer M, Schmidt W, Spiera R, Tronnier D, Wagner A, Whitlock M, Matteson EL, Dasgupta B; European League Against Rheumatism; American College of Rheumatology.

Arthritis Rheumatol. 2015 Oct;67(10):2569-80. doi: 10.1002/art.39333.

36.

Robustness to noise in gene expression evolves despite epistatic constraints in a model of gene networks.

Draghi J, Whitlock M.

Evolution. 2015 Sep;69(9):2345-58. doi: 10.1111/evo.12732. Epub 2015 Aug 27.

PMID:
26200818
37.

A clever solution to a vexing problem.

Whitlock MC.

Mol Ecol. 2015 Jul;24(14):3513-4. doi: 10.1111/mec.13280.

PMID:
26174126
38.

Evaluating methods for estimating local effective population size with and without migration.

Gilbert KJ, Whitlock MC.

Evolution. 2015 Aug;69(8):2154-66. doi: 10.1111/evo.12713. Epub 2015 Jul 21.

PMID:
26118738
39.

Learning to identify CNS drug action and efficacy using multistudy fMRI data.

Duff EP, Vennart W, Wise RG, Howard MA, Harris RE, Lee M, Wartolowska K, Wanigasekera V, Wilson FJ, Whitlock M, Tracey I, Woolrich MW, Smith SM.

Sci Transl Med. 2015 Feb 11;7(274):274ra16. doi: 10.1126/scitranslmed.3008438.

PMID:
25673761
40.

The relative power of genome scans to detect local adaptation depends on sampling design and statistical method.

Lotterhos KE, Whitlock MC.

Mol Ecol. 2015 Mar;24(5):1031-46. doi: 10.1111/mec.13100. Epub 2015 Feb 18.

PMID:
25648189
41.

Overdominance interacts with linkage to determine the rate of adaptation to a new optimum.

Draghi J, Whitlock MC.

J Evol Biol. 2015 Jan;28(1):95-104. doi: 10.1111/jeb.12547. Epub 2014 Dec 2.

42.

QST-FST comparisons with unbalanced half-sib designs.

Gilbert KJ, Whitlock MC.

Mol Ecol Resour. 2015 Mar;15(2):262-7. doi: 10.1111/1755-0998.12303. Epub 2014 Aug 8.

PMID:
25042150
43.

Improving fire safety in an ambulatory setting.

Whitlock ME, Boone WR.

Nursing. 2014 Aug;44(8):67. doi: 10.1097/01.NURSE.0000451537.40340.d0. No abstract available.

PMID:
25025259
44.

Evaluation of demographic history and neutral parameterization on the performance of FST outlier tests.

Lotterhos KE, Whitlock MC.

Mol Ecol. 2014 May;23(9):2178-92. doi: 10.1111/mec.12725. Epub 2014 Apr 11.

45.

Phenotypic plasticity facilitates mutational variance, genetic variance, and evolvability along the major axis of environmental variation.

Draghi JA, Whitlock MC.

Evolution. 2012 Sep;66(9):2891-902. doi: 10.1111/j.1558-5646.2012.01649.x. Epub 2012 May 1.

PMID:
22946810
46.

Experimental evolution.

Kawecki TJ, Lenski RE, Ebert D, Hollis B, Olivieri I, Whitlock MC.

Trends Ecol Evol. 2012 Oct;27(10):547-60. doi: 10.1016/j.tree.2012.06.001. Epub 2012 Jul 21. Review.

47.

Multilocus estimation of selfing and its heritability.

McClure NS, Whitlock MC.

Heredity (Edinb). 2012 Sep;109(3):173-9. doi: 10.1038/hdy.2012.27. Epub 2012 May 23.

48.

Characterization, optimisation and process robustness of a co-processed mannitol for the development of orally disintegrating tablets.

Soh JL, Grachet M, Whitlock M, Lukas T.

Pharm Dev Technol. 2013 Feb;18(1):172-85. doi: 10.3109/10837450.2012.685658. Epub 2012 May 14.

PMID:
22582882
49.

Q(ST) in a hierarchically structured population.

Whitlock MC, Gilbert KJ.

Mol Ecol Resour. 2012 May;12(3):481-3. doi: 10.1111/j.1755-0998.2012.03122.x. Epub 2012 Feb 16.

PMID:
22336101
50.

Sewall Wright Award.

Arnold SJ; Sewall Wright Award Committee, Antonovics J, Power M, Whitlock M.

Am Nat. 2012 Jan;179(1):iv. doi: 10.1086/664446. No abstract available.

PMID:
22173471

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