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Items: 35


Identification of ion-channel modulators that protect against aminoglycoside-induced hair cell death.

Kenyon EJ, Kirkwood NK, Kitcher SR, O'Reilly M, Derudas M, Cantillon DM, Goodyear RJ, Secker A, Baxendale S, Bull JC, Waddell SJ, Whitfield TT, Ward SE, Kros CJ, Richardson GP.

JCI Insight. 2017 Dec 21;2(24). pii: 96773. doi: 10.1172/jci.insight.96773.


Comparison of Approaches for Stroke Prophylaxis in Patients with Non-Valvular Atrial Fibrillation: Network Meta-Analyses of Randomized Controlled Trials.

Bajaj NS, Kalra R, Patel N, Hashim T, Godara H, Ather S, Arora G, Pasala T, Whitfield TT, McGiffin DC, Ahmed MI, Lloyd SG, Limdi NA, Arora P.

PLoS One. 2016 Oct 5;11(10):e0163608. doi: 10.1371/journal.pone.0163608. eCollection 2016.


Sculpting the labyrinth: Morphogenesis of the developing inner ear.

Alsina B, Whitfield TT.

Semin Cell Dev Biol. 2017 May;65:47-59. doi: 10.1016/j.semcdb.2016.09.015. Epub 2016 Sep 26. Review.


Methods to study the development, anatomy, and function of the zebrafish inner ear across the life course.

Baxendale S, Whitfield TT.

Methods Cell Biol. 2016;134:165-209. doi: 10.1016/bs.mcb.2016.02.007. Epub 2016 Mar 9.


Development of the inner ear.

Whitfield TT.

Curr Opin Genet Dev. 2015 Jun;32:112-8. doi: 10.1016/j.gde.2015.02.006. Epub 2015 Mar 19. Review.


Otolith tethering in the zebrafish otic vesicle requires Otogelin and α-Tectorin.

Stooke-Vaughan GA, Obholzer ND, Baxendale S, Megason SG, Whitfield TT.

Development. 2015 Mar 15;142(6):1137-45. doi: 10.1242/dev.116632.


RA and FGF signalling are required in the zebrafish otic vesicle to pattern and maintain ventral otic identities.

Maier EC, Whitfield TT.

PLoS Genet. 2014 Dec 4;10(12):e1004858. doi: 10.1371/journal.pgen.1004858. eCollection 2014 Dec.


Julian Hart Lewis, F.R.S. (1946–2014).

Whitfield TT, Monk N.

Dev Cell. 2014 Jun 9;29(5):507-9. No abstract available.


Sensational placodes: neurogenesis in the otic and olfactory systems.

Maier EC, Saxena A, Alsina B, Bronner ME, Whitfield TT.

Dev Biol. 2014 May 1;389(1):50-67. doi: 10.1016/j.ydbio.2014.01.023. Epub 2014 Feb 6. Review.


Semicircular canal morphogenesis in the zebrafish inner ear requires the function of gpr126 (lauscher), an adhesion class G protein-coupled receptor gene.

Geng FS, Abbas L, Baxendale S, Holdsworth CJ, Swanson AG, Slanchev K, Hammerschmidt M, Topczewski J, Whitfield TT.

Development. 2013 Nov;140(21):4362-74. doi: 10.1242/dev.098061. Epub 2013 Sep 25.


Shedding new light on the origins of olfactory neurons.

Whitfield TT.

Elife. 2013 Mar 26;2:e00648. doi: 10.7554/eLife.00648.


The role of hair cells, cilia and ciliary motility in otolith formation in the zebrafish otic vesicle.

Stooke-Vaughan GA, Huang P, Hammond KL, Schier AF, Whitfield TT.

Development. 2012 May;139(10):1777-87. doi: 10.1242/dev.079947. Epub 2012 Mar 29.


Ototoxin-induced cellular damage in neuromasts disrupts lateral line function in larval zebrafish.

Buck LM, Winter MJ, Redfern WS, Whitfield TT.

Hear Res. 2012 Feb;284(1-2):67-81. doi: 10.1016/j.heares.2011.12.001. Epub 2011 Dec 11.


Fgf and Hh signalling act on a symmetrical pre-pattern to specify anterior and posterior identity in the zebrafish otic placode and vesicle.

Hammond KL, Whitfield TT.

Development. 2011 Sep;138(18):3977-87. doi: 10.1242/dev.066639. Epub 2011 Aug 10.


Aldosterone decreases glucose-stimulated insulin secretion in vivo in mice and in murine islets.

Luther JM, Luo P, Kreger MT, Brissova M, Dai C, Whitfield TT, Kim HS, Wasserman DH, Powers AC, Brown NJ.

Diabetologia. 2011 Aug;54(8):2152-63. doi: 10.1007/s00125-011-2158-9. Epub 2011 Apr 26.


Functional and developmental expression of a zebrafish Kir1.1 (ROMK) potassium channel homologue Kcnj1.

Abbas L, Hajihashemi S, Stead LF, Cooper GJ, Ware TL, Munsey TS, Whitfield TT, White SJ.

J Physiol. 2011 Mar 15;589(Pt 6):1489-503. doi: 10.1113/jphysiol.2010.200295. Epub 2011 Jan 24.


Repression of Hedgehog signalling is required for the acquisition of dorsolateral cell fates in the zebrafish otic vesicle.

Hammond KL, van Eeden FJ, Whitfield TT.

Development. 2010 Apr;137(8):1361-71. doi: 10.1242/dev.045666. Epub 2010 Mar 10.


Expression of zebrafish hip: response to Hedgehog signalling, comparison with ptc1 expression, and possible role in otic patterning.

Hammond KL, Whitfield TT.

Gene Expr Patterns. 2009 Sep;9(6):391-6. doi: 10.1016/j.gep.2009.06.006. Epub 2009 Jun 21.


Expression of patched, prdm1 and engrailed in the lamprey somite reveals conserved responses to Hedgehog signaling.

Hammond KL, Baxendale S, McCauley DW, Ingham PW, Whitfield TT.

Evol Dev. 2009 Jan-Feb;11(1):27-40. doi: 10.1111/j.1525-142X.2008.00300.x.


A late role for bmp2b in the morphogenesis of semicircular canal ducts in the zebrafish inner ear.

Hammond KL, Loynes HE, Mowbray C, Runke G, Hammerschmidt M, Mullins MC, Hildreth V, Chaudhry B, Whitfield TT.

PLoS One. 2009;4(2):e4368. doi: 10.1371/journal.pone.0004368. Epub 2009 Feb 3.


A zebrafish model for Waardenburg syndrome type IV reveals diverse roles for Sox10 in the otic vesicle.

Dutton K, Abbas L, Spencer J, Brannon C, Mowbray C, Nikaido M, Kelsh RN, Whitfield TT.

Dis Model Mech. 2009 Jan-Feb;2(1-2):68-83. doi: 10.1242/dmm.001164. Epub 2008 Dec 22.


Axial patterning in the developing vertebrate inner ear.

Whitfield TT, Hammond KL.

Int J Dev Biol. 2007;51(6-7):507-20. Review.


Lateral line: precocious phenotypes and planar polarity.

Whitfield TT.

Curr Biol. 2005 Jan 26;15(2):R67-70. Review.


The zebrafish dog-eared mutation disrupts eya1, a gene required for cell survival and differentiation in the inner ear and lateral line.

Kozlowski DJ, Whitfield TT, Hukriede NA, Lam WK, Weinberg ES.

Dev Biol. 2005 Jan 1;277(1):27-41.


Hedgehog signalling is required for correct anteroposterior patterning of the zebrafish otic vesicle.

Hammond KL, Loynes HE, Folarin AA, Smith J, Whitfield TT.

Development. 2003 Apr;130(7):1403-17.


Zebrafish as a model for hearing and deafness.

Whitfield TT.

J Neurobiol. 2002 Nov 5;53(2):157-71. Review.


Development of the zebrafish inner ear.

Whitfield TT, Riley BB, Chiang MY, Phillips B.

Dev Dyn. 2002 Apr;223(4):427-58. Review.


Expression of BMP signalling pathway members in the developing zebrafish inner ear and lateral line.

Mowbray C, Hammerschmidt M, Whitfield TT.

Mech Dev. 2001 Oct;108(1-2):179-84.


Mutations affecting development of the zebrafish inner ear and lateral line.

Whitfield TT, Granato M, van Eeden FJ, Schach U, Brand M, Furutani-Seiki M, Haffter P, Hammerschmidt M, Heisenberg CP, Jiang YJ, Kane DA, Kelsh RN, Mullins MC, Odenthal J, Nüsslein-Volhard C.

Development. 1996 Dec;123:241-54.


Early embryonic expression of XLPOU-60, a Xenopus POU-domain protein.

Whitfield TT, Heasman J, Wylie CC.

Dev Biol. 1995 Jun;169(2):759-69.


Nonsense-mediated mRNA decay in Xenopus oocytes and embryos.

Whitfield TT, Sharpe CR, Wylie CC.

Dev Biol. 1994 Oct;165(2):731-4.


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