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Items: 1 to 50 of 294

1.

Dr John Tytler (1787-1837), Superintendent of the Native Medical Institution, Calcutta.

Whitfield MJ.

J Med Biogr. 2019 Nov 26:967772019877133. doi: 10.1177/0967772019877133. [Epub ahead of print]

PMID:
31771408
2.

Global skin gene expression analysis of early diffuse cutaneous systemic sclerosis shows a prominent innate and adaptive inflammatory profile.

Skaug B, Khanna D, Swindell WR, Hinchcliff ME, Frech TM, Steen VD, Hant FN, Gordon JK, Shah AA, Zhu L, Zheng WJ, Browning JL, Barron AMS, Wu M, Visvanathan S, Baum P, Franks JM, Whitfield ML, Shanmugam VK, Domsic RT, Castelino FV, Bernstein EJ, Wareing N, Lyons MA, Ying J, Charles J, Mayes MD, Assassi S.

Ann Rheum Dis. 2019 Nov 25. pii: annrheumdis-2019-215894. doi: 10.1136/annrheumdis-2019-215894. [Epub ahead of print]

PMID:
31767698
3.

Community-Engaged Approaches to Address the Ethical Concerns of Maternal Mental Health Disparities Research.

Hernandez ND, Dorsey J, Glass DM, Pope E, Worthy N, Blasingame E, Gooding J, Braxton P, Whitfield M, Dotson Y.

J Health Care Poor Underserved. 2019;30(4S):12-20. doi: 10.1353/hpu.2019.0110.

PMID:
31735713
4.

Mutations in TTC29, Encoding an Evolutionarily Conserved Axonemal Protein, Result in Asthenozoospermia and Male Infertility.

Lorès P, Dacheux D, Kherraf ZE, Nsota Mbango JF, Coutton C, Stouvenel L, Ialy-Radio C, Amiri-Yekta A, Whitfield M, Schmitt A, Cazin C, Givelet M, Ferreux L, Fourati Ben Mustapha S, Halouani L, Marrakchi O, Daneshipour A, El Khouri E, Do Cruzeiro M, Favier M, Guillonneau F, Chaudhry M, Sakheli Z, Wolf JP, Patrat C, Gacon G, Savinov SN, Hosseini SH, Robinson DR, Zouari R, Ziyyat A, Arnoult C, Dulioust E, Bonhivers M, Ray PF, Touré A.

Am J Hum Genet. 2019 Dec 5;105(6):1148-1167. doi: 10.1016/j.ajhg.2019.10.007. Epub 2019 Nov 14.

PMID:
31735292
5.

State of the art and a mixed-method personalized approach to assess patient perceptions on medical record sharing and sensitivity.

Soni H, Grando A, Murcko A, Diaz S, Mukundan M, Idouraine N, Karway G, Todd M, Chern D, Dye C, Whitfield MJ.

J Biomed Inform. 2019 Nov 11;101:103338. doi: 10.1016/j.jbi.2019.103338. [Epub ahead of print]

PMID:
31726102
6.

Shared and distinct mechanisms of fibrosis.

Distler JHW, Györfi AH, Ramanujam M, Whitfield ML, Königshoff M, Lafyatis R.

Nat Rev Rheumatol. 2019 Dec;15(12):705-730. doi: 10.1038/s41584-019-0322-7. Epub 2019 Nov 11. Review.

PMID:
31712723
7.

Systemic Sclerosis Dermal Fibroblasts Induce Cutaneous Fibrosis Through LOXL4: New Evidence from 3D Skin-like Tissues.

Huang M, Cai G, Baugh LM, Liu Z, Smith A, Watson M, Popovich D, Zhang T, Stawski LS, Trojanowska M, Georgakoudi I, Black LD 3rd, Pioli PA, Whitfield ML, Garlick J.

Arthritis Rheumatol. 2019 Nov 9. doi: 10.1002/art.41163. [Epub ahead of print]

PMID:
31705627
8.

John King, the Bristol surgeon and friend of artists and poets.

Whitfield MJ.

J Med Biogr. 2019 Sep 2:967772019873560. doi: 10.1177/0967772019873560. [Epub ahead of print]

PMID:
31475886
9.

Design and Pilot Testing of an English and Spanish Behavioral Health Patient Survey on Data Privacy.

Aliste MP, Grando A, Murcko A, Soni H, Todd M, Mukundan M, Saks M, Horrow C, Sharp R, Dye C, Chern D, Whitfield MJ, Callesen M.

Stud Health Technol Inform. 2019 Aug 21;264:1891-1892. doi: 10.3233/SHTI190699.

PMID:
31438393
10.

Perceptions and Preferences About Granular Data Sharing and Privacy of Behavioral Health Patients.

Soni H, Grando A, Aliste MP, Murcko A, Todd M, Mukundan M, Saks M, Horrow C, Sharp R, Dye C, Chern D, Whitfield MJ, Callesen M.

Stud Health Technol Inform. 2019 Aug 21;264:1361-1365. doi: 10.3233/SHTI190449.

PMID:
31438148
11.

Abatacept in Early Diffuse Cutaneous Systemic Sclerosis - Results of a Phase 2 Investigator-Initiated, Multicenter, Double-Blind Randomized Placebo-Controlled Trial.

Khanna D, Spino C, Johnson S, Chung L, Whitfield M, Denton CP, Berrocal V, Franks J, Mehta B, Molitor J, Steen VD, Lafyatis R, Simms RW, Gill A, Kafaja S, Frech TM, Hsu V, Domsic RT, Pope JE, Gordon JK, Mayes MD, Schiopu E, Young A, Sandorfi N, Park J, Hant FN, Bernstein EJ, Chatterjee S, Castelino FV, Ajam A, Wang Y, Wood T, Allanore Y, Matucci-Cerinic M, Distler O, Singer O, Bush E, Fox D, Furst DE.

Arthritis Rheumatol. 2019 Jul 24. doi: 10.1002/art.41055. [Epub ahead of print]

PMID:
31342624
12.

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

Whitfield M, Thomas L, Bequignon E, Schmitt A, Stouvenel L, Montantin G, Tissier S, Duquesnoy P, Copin B, Chantot S, Dastot F, Faucon C, Barbotin AL, Loyens A, Siffroi JP, Papon JF, Escudier E, Amselem S, Mitchell V, Touré A, Legendre M.

Am J Hum Genet. 2019 Jul 3;105(1):198-212. doi: 10.1016/j.ajhg.2019.04.015. Epub 2019 Jun 6.

PMID:
31178125
13.

Impairment of sperm maturation and capacitation due to diet-dependent cholesterol overload.

Saez F, Whitfield M, Drevet JR.

Andrology. 2019 Sep;7(5):654-661. doi: 10.1111/andr.12634. Epub 2019 Jun 4.

PMID:
31161683
14.

OTUD6B-AS1 Might Be a Novel Regulator of Apoptosis in Systemic Sclerosis.

Takata M, Pachera E, Frank-Bertoncelj M, Kozlova A, Jüngel A, Whitfield ML, Assassi S, Calcagni M, de Vries-Bouwstra J, Huizinga TW, Kurreeman F, Kania G, Distler O.

Front Immunol. 2019 May 17;10:1100. doi: 10.3389/fimmu.2019.01100. eCollection 2019.

15.

Senescence Signature in Skin Biopsies From Systemic Sclerosis Patients Treated With Senolytic Therapy: Potential Predictor of Clinical Response?

Martyanov V, Whitfield ML, Varga J.

Arthritis Rheumatol. 2019 Oct;71(10):1766-1767. doi: 10.1002/art.40934. Epub 2019 Sep 2. No abstract available.

PMID:
31112009
16.

Examining the impact of a summer learning program on children's weight status and cardiorespiratory fitness: A natural experiment.

Hunt ET, Whitfield ML, Brazendale K, Beets MW, Weaver RG.

Eval Program Plann. 2019 Jun;74:84-90. doi: 10.1016/j.evalprogplan.2019.02.009. Epub 2019 Feb 18.

PMID:
30939299
17.

A Machine Learning Classifier for Assigning Individual Patients With Systemic Sclerosis to Intrinsic Molecular Subsets.

Franks JM, Martyanov V, Cai G, Wang Y, Li Z, Wood TA, Whitfield ML.

Arthritis Rheumatol. 2019 Oct;71(10):1701-1710. doi: 10.1002/art.40898. Epub 2019 Sep 2.

PMID:
30920766
18.

Live-cell phenotypic-biomarker microfluidic assay for the risk stratification of cancer patients via machine learning.

Manak MS, Varsanik JS, Hogan BJ, Whitfield MJ, Su WR, Joshi N, Steinke N, Min A, Berger D, Saphirstein RJ, Dixit G, Meyyappan T, Chu HM, Knopf KB, Albala DM, Sant GR, Chander AC.

Nat Biomed Eng. 2018 Oct;2(10):761-772. doi: 10.1038/s41551-018-0285-z. Epub 2018 Sep 17.

19.

BioMethyl: an R package for biological interpretation of DNA methylation data.

Wang Y, Franks JM, Whitfield ML, Cheng C.

Bioinformatics. 2019 Oct 1;35(19):3635-3641. doi: 10.1093/bioinformatics/btz137.

20.

Microbiome dysbiosis is associated with disease duration and increased inflammatory gene expression in systemic sclerosis skin.

Johnson ME, Franks JM, Cai G, Mehta BK, Wood TA, Archambault K, Pioli PA, Simms RW, Orzechowski N, Arron S, Whitfield ML.

Arthritis Res Ther. 2019 Feb 6;21(1):49. doi: 10.1186/s13075-019-1816-z.

21.

Lysyl oxidase enzymes mediate TGF-β1-induced fibrotic phenotypes in human skin-like tissues.

Huang M, Liu Z, Baugh L, DeFuria J, Maione A, Smith A, Kashpur O, Black Iii LD, Georgakoudi I, Whitfield ML, Garlick J.

Lab Invest. 2019 Apr;99(4):514-527. doi: 10.1038/s41374-018-0159-8. Epub 2018 Dec 19.

PMID:
30568176
22.

Aromatic donor-acceptor interaction promoted catalyst assemblies for hydrolytic kinetic resolution of epichlorohydrin.

Blechschmidt DR, Woodhouse MD, Inagaki S, Whitfield M, Ogunsanya A, Yoder A, Lilly D, Heim EW, Soucie LN, Liang J, Liu Y.

Org Biomol Chem. 2018 Dec 19;17(1):172-180. doi: 10.1039/c8ob02249f.

PMID:
30534697
23.

Impacts on quality: Enjoyment factors in blind and low vision audience entertainment ratings: A qualitative study.

Naraine MD, Fels DI, Whitfield M.

PLoS One. 2018 Dec 3;13(12):e0208165. doi: 10.1371/journal.pone.0208165. eCollection 2018.

24.

Patients with systemic sclerosis-associated pulmonary arterial hypertension express a genomic signature distinct from patients with interstitial lung disease.

Moll M, Christmann RB, Zhang Y, Whitfield ML, Wang YM, Rice L, Stratton E, Lafyatis R, Farber HW.

J Scleroderma Relat Disord. 2018 Oct;3(3):242-248. doi: 10.1177/2397198318764780. Epub 2018 Mar 22.

25.

PROBING MECHANICAL PROPERTIES OF BRAIN IN A TUBEROUS SCLEROSIS MODEL OF AUTISM.

Qing B, Canovic EP, Mijailovic AS, Jagielska A, Whitfield MJ, Lowe AL, Kelly EH, Turner D, Sahin M, Van Vliet K.

J Biomech Eng. 2018 Oct 22. doi: 10.1115/1.4040945. [Epub ahead of print]

PMID:
30347048
26.

Slc26a3 deficiency is associated with epididymis dysplasia and impaired sperm fertilization potential in the mouse.

El Khouri E, Whitfield M, Stouvenel L, Kini A, Riederer B, Lores P, Roemermann D, di Stefano G, Drevet JR, Saez F, Seidler U, Touré A.

Mol Reprod Dev. 2018 Aug;85(8-9):682-695. doi: 10.1002/mrd.23055. Epub 2018 Sep 7.

PMID:
30118583
27.

The potential use of rifabutin for treatment of patients diagnosed with rifampicin-resistant tuberculosis.

Whitfield MG, Warren RM, Mathys V, Scott L, De Vos E, Stevens W, Streicher EM, Groenen G, Sirgel FA, Van Rie A.

J Antimicrob Chemother. 2018 Oct 1;73(10):2667-2674. doi: 10.1093/jac/dky248.

28.

Current State of Electronic Consent Processes in Behavioral Health: Outcomes from an Observational Study.

Soni H, Grando A, Murcko A, Bayuk M, Chandrashekar P, Mukundan M, Abrams M, Aliste MP, Hiestand M, Varkey J, Zhou W, Horrow C, Saks M, Sharp R, Whitfield MJ, Callesen M, Dye C, Chern D.

AMIA Annu Symp Proc. 2018 Apr 16;2017:1607-1616. eCollection 2017.

29.

Ecological genomics predicts climate vulnerability in an endangered southwestern songbird.

Ruegg K, Bay RA, Anderson EC, Saracco JF, Harrigan RJ, Whitfield M, Paxton EH, Smith TB.

Ecol Lett. 2018 Jul;21(7):1085-1096. doi: 10.1111/ele.12977. Epub 2018 May 9.

PMID:
29745027
30.

Identifying and Quantifying the Unintended Variability in Common Systematic Observation Instruments to Measure Youth Physical Activity.

Weaver RG, Beighle A, Erwin H, Whitfield M, Beets MW, Hardin JW.

J Phys Act Health. 2018 Sep 1;15(9):651-660. doi: 10.1123/jpah.2017-0375. Epub 2018 May 10.

PMID:
29742990
31.

The mechanistic implications of gene expression studies in SSc: Insights from Systems Biology.

Taroni JN, Mahoney JM, Whitfield ML.

Curr Treatm Opt Rheumatol. 2017 Sep;3(3):181-192. doi: 10.1007/s40674-017-0072-0. Epub 2017 Jul 29. No abstract available.

32.

Avian thermoregulation in the heat: phylogenetic variation among avian orders in evaporative cooling capacity and heat tolerance.

Smit B, Whitfield MC, Talbot WA, Gerson AR, McKechnie AE, Wolf BO.

J Exp Biol. 2018 Mar 19;221(Pt 6). pii: jeb174870. doi: 10.1242/jeb.174870.

33.

Comprehensive overview of murine epididymal mononuclear phagocytes and lymphocytes: Unexpected populations arise.

Voisin A, Whitfield M, Damon-Soubeyrand C, Goubely C, Henry-Berger J, Saez F, Kocer A, Drevet JR, Guiton R.

J Reprod Immunol. 2018 Apr;126:11-17. doi: 10.1016/j.jri.2018.01.003. Epub 2018 Jan 31.

PMID:
29421624
34.

Mycophenolate Mofetil Treatment of Systemic Sclerosis Reduces Myeloid Cell Numbers and Attenuates the Inflammatory Gene Signature in Skin.

Hinchcliff M, Toledo DM, Taroni JN, Wood TA, Franks JM, Ball MS, Hoffmann A, Amin SM, Tan AU, Tom K, Nesbeth Y, Lee J, Ma M, Aren K, Carns MA, Pioli PA, Whitfield ML.

J Invest Dermatol. 2018 Jun;138(6):1301-1310. doi: 10.1016/j.jid.2018.01.006. Epub 2018 Jan 31.

35.

Feature specific quantile normalization enables cross-platform classification of molecular subtypes using gene expression data.

Franks JM, Cai G, Whitfield ML.

Bioinformatics. 2018 Jun 1;34(11):1868-1874. doi: 10.1093/bioinformatics/bty026.

36.

Antisense Long Non-Coding RNAs Are Deregulated in Skin Tissue of Patients with Systemic Sclerosis.

Messemaker TC, Chadli L, Cai G, Goelela VS, Boonstra M, Dorjée AL, Andersen SN, Mikkers HMM, van 't Hof P, Mei H, Distler O, Draisma HHM, Johnson ME, Orzechowski NM, Simms RW, Toes REM, Aarbiou J, Huizinga TW, Whitfield ML, DeGroot J, de Vries-Bouwstra J, Kurreeman F.

J Invest Dermatol. 2018 Apr;138(4):826-835. doi: 10.1016/j.jid.2017.09.053. Epub 2017 Nov 24.

37.

Novel lung imaging biomarkers and skin gene expression subsetting in dasatinib treatment of systemic sclerosis-associated interstitial lung disease.

Martyanov V, Kim GJ, Hayes W, Du S, Ganguly BJ, Sy O, Lee SK, Bogatkevich GS, Schieven GL, Schiopu E, Marangoni RG, Goldin J, Whitfield ML, Varga J.

PLoS One. 2017 Nov 9;12(11):e0187580. doi: 10.1371/journal.pone.0187580. eCollection 2017.

38.

Belimumab for the Treatment of Early Diffuse Systemic Sclerosis: Results of a Randomized, Double-Blind, Placebo-Controlled, Pilot Trial.

Gordon JK, Martyanov V, Franks JM, Bernstein EJ, Szymonifka J, Magro C, Wildman HF, Wood TA, Whitfield ML, Spiera RF.

Arthritis Rheumatol. 2018 Feb;70(2):308-316. doi: 10.1002/art.40358. Epub 2017 Dec 29.

39.

Dyslipidemia alters sperm maturation and capacitation in LXR-null mice.

Whitfield M, Guiton R, Rispal J, Acar N, Kocer A, Drevet JR, Saez F.

Reproduction. 2017 Dec;154(6):827-842. doi: 10.1530/REP-17-0467. Epub 2017 Oct 2.

PMID:
28971895
40.

Limited cutaneous systemic sclerosis skin demonstrates distinct molecular subsets separated by a cardiovascular development gene expression signature.

Derrett-Smith EC, Martyanov V, Chighizola CB, Moinzadeh P, Campochiaro C, Khan K, Wood TA, Meroni PL, Abraham DJ, Ong VH, Lafyatis R, Whitfield ML, Denton CP.

Arthritis Res Ther. 2017 Jul 4;19(1):156. doi: 10.1186/s13075-017-1360-7.

41.

Evaluation of a novel line probe assay to detect resistance to pyrazinamide, a key drug used for tuberculosis treatment.

Driesen M, Kondo Y, de Jong BC, Torrea G, Asnong S, Desmaretz C, Mostofa KSM, Tahseen S, Whitfield MG, Cirillo DM, Miotto P, Cabibbe AM, Rigouts L.

Clin Microbiol Infect. 2018 Jan;24(1):60-64. doi: 10.1016/j.cmi.2017.05.026. Epub 2017 Jun 3.

42.

Population effect model identifies gene expression predictors of survival outcomes in lung adenocarcinoma for both Caucasian and Asian patients.

Cai G, Xiao F, Cheng C, Li Y, Amos CI, Whitfield ML.

PLoS One. 2017 Apr 20;12(4):e0175850. doi: 10.1371/journal.pone.0175850. eCollection 2017.

43.

A novel multi-network approach reveals tissue-specific cellular modulators of fibrosis in systemic sclerosis.

Taroni JN, Greene CS, Martyanov V, Wood TA, Christmann RB, Farber HW, Lafyatis RA, Denton CP, Hinchcliff ME, Pioli PA, Mahoney JM, Whitfield ML.

Genome Med. 2017 Mar 23;9(1):27. doi: 10.1186/s13073-017-0417-1.

44.

Myeloid Cells That Impair Immunotherapy Are Restored in Melanomas with Acquired Resistance to BRAF Inhibitors.

Steinberg SM, Shabaneh TB, Zhang P, Martyanov V, Li Z, Malik BT, Wood TA, Boni A, Molodtsov A, Angeles CV, Curiel TJ, Whitfield ML, Turk MJ.

Cancer Res. 2017 Apr 1;77(7):1599-1610. doi: 10.1158/0008-5472.CAN-16-1755. Epub 2017 Feb 15.

45.

Integrated, multicohort analysis of systemic sclerosis identifies robust transcriptional signature of disease severity.

Lofgren S, Hinchcliff M, Carns M, Wood T, Aren K, Arroyo E, Cheung P, Kuo A, Valenzuela A, Haemel A, Wolters PJ, Gordon J, Spiera R, Assassi S, Boin F, Chung L, Fiorentino D, Utz PJ, Whitfield ML, Khatri P.

JCI Insight. 2016 Dec 22;1(21):e89073. doi: 10.1172/jci.insight.89073.

46.

A Functional Genomic Meta-Analysis of Clinical Trials in Systemic Sclerosis: Toward Precision Medicine and Combination Therapy.

Taroni JN, Martyanov V, Mahoney JM, Whitfield ML.

J Invest Dermatol. 2017 May;137(5):1033-1041. doi: 10.1016/j.jid.2016.12.007. Epub 2016 Dec 21.

47.

A subset of replication-dependent histone mRNAs are expressed as polyadenylated RNAs in terminally differentiated tissues.

Lyons SM, Cunningham CH, Welch JD, Groh B, Guo AY, Wei B, Whitfield ML, Xiong Y, Marzluff WF.

Nucleic Acids Res. 2016 Nov 2;44(19):9190-9205. Epub 2016 Jul 8.

48.

Characterizing Multiscale Mechanical Properties of Brain Tissue Using Atomic Force Microscopy, Impact Indentation, and Rheometry.

Canovic EP, Qing B, Mijailovic AS, Jagielska A, Whitfield MJ, Kelly E, Turner D, Sahin M, Van Vliet KJ.

J Vis Exp. 2016 Sep 6;(115). doi: 10.3791/54201.

49.

Avian thermoregulation in the heat: evaporative cooling capacity in an archetypal desert specialist, Burchell's sandgrouse (Pterocles burchelli).

McKechnie AE, Smit B, Whitfield MC, Noakes MJ, Talbot WA, Garcia M, Gerson AR, Wolf BO.

J Exp Biol. 2016 Aug 1;219(Pt 15):2409. doi: 10.1242/jeb.146563. No abstract available.

50.

Prevalence of pyrazinamide resistance across the spectrum of drug resistant phenotypes of Mycobacterium tuberculosis.

Whitfield MG, Streicher EM, Dolby T, Simpson JA, Sampson SL, Van Helden PD, Van Rie A, Warren RM.

Tuberculosis (Edinb). 2016 Jul;99:128-30. doi: 10.1016/j.tube.2016.05.003. Epub 2016 May 30.

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