Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 131

1.

Thirty years of marine debris in the Southern Ocean: Annual surveys of two island shores in the Scotia Sea.

Waluda CM, Staniland IJ, Dunn MJ, Thorpe SE, Grilly E, Whitelaw M, Hughes KA.

Environ Int. 2020 Jan 11;136:105460. doi: 10.1016/j.envint.2020.105460. [Epub ahead of print]

PMID:
31935563
2.

Functional Analysis of the SIM1 Variant p.G715V in 2 Patients With Obesity.

Blackburn PR, Sullivan AE, Gerassimou AG, Kleinendorst L, Bersten DC, Cooiman M, Harris KG, Wierenga KJ, Klee EW, van Gerpen JA, Ross OA, van Haelst MM, Whitelaw ML, Caulfield TR, Atwal PS.

J Clin Endocrinol Metab. 2020 Jan 1;105(1). pii: dgz192. doi: 10.1210/clinem/dgz192.

PMID:
31872862
3.

Predictors of Complications in Anorexia Nervosa and Atypical Anorexia Nervosa: Degree of Underweight or Extent and Recency of Weight Loss?

Whitelaw M, Lee KJ, Gilbertson H, Sawyer SM.

J Adolesc Health. 2018 Dec;63(6):717-723. doi: 10.1016/j.jadohealth.2018.08.019.

PMID:
30454732
4.

Disruption of the homeodomain transcription factor orthopedia homeobox (Otp) is associated with obesity and anxiety.

Moir L, Bochukova EG, Dumbell R, Banks G, Bains RS, Nolan PM, Scudamore C, Simon M, Watson KA, Keogh J, Henning E, Hendricks A, O'Rahilly S, Barroso I; UK10K consortium, Sullivan AE, Bersten DC, Whitelaw ML, Kirsch S, Bentley E, Farooqi IS, Cox RD.

Mol Metab. 2017 Nov;6(11):1419-1428. doi: 10.1016/j.molmet.2017.08.006. Epub 2017 Aug 24.

5.

HIF has Biff - Crosstalk between HIF1a and the family of bHLH/PAS proteins.

Button EL, Bersten DC, Whitelaw ML.

Exp Cell Res. 2017 Jul 15;356(2):141-145. doi: 10.1016/j.yexcr.2017.03.055. Epub 2017 Mar 31. Review.

PMID:
28366537
6.

MAGED1 is a novel regulator of a select subset of bHLH PAS transcription factors.

Sullivan AE, Peet DJ, Whitelaw ML.

FEBS J. 2016 Sep;283(18):3488-502. doi: 10.1111/febs.13824. Epub 2016 Aug 18.

7.

Physical and Psychological Morbidity in Adolescents With Atypical Anorexia Nervosa.

Sawyer SM, Whitelaw M, Le Grange D, Yeo M, Hughes EK.

Pediatrics. 2016 Apr;137(4). pii: e20154080. doi: 10.1542/peds.2015-4080. Epub 2016 Mar 29.

8.

A systematic review of approaches to refeeding in patients with anorexia nervosa.

Garber AK, Sawyer SM, Golden NH, Guarda AS, Katzman DK, Kohn MR, Le Grange D, Madden S, Whitelaw M, Redgrave GW.

Int J Eat Disord. 2016 Mar;49(3):293-310. doi: 10.1002/eat.22482. Epub 2015 Dec 12. Review.

9.

Accretor: Generative Materiality in the Work of Driessens and Verstappen.

Whitelaw M.

Artif Life. Summer 2015;21(3):307-12. doi: 10.1162/ARTL_a_00171.

PMID:
26280071
10.

Inducible and reversible lentiviral and Recombination Mediated Cassette Exchange (RMCE) systems for controlling gene expression.

Bersten DC, Sullivan AE, Li D, Bhakti V, Bent SJ, Whitelaw ML.

PLoS One. 2015 Mar 13;10(3):e0116373. doi: 10.1371/journal.pone.0116373. eCollection 2015.

11.

Oxygen-dependent hydroxylation by FIH regulates the TRPV3 ion channel.

Karttunen S, Duffield M, Scrimgeour NR, Squires L, Lim WL, Dallas ML, Scragg JL, Chicher J, Dave KA, Whitelaw ML, Peers C, Gorman JJ, Gleadle JM, Rychkov GY, Peet DJ.

J Cell Sci. 2015 Jan 15;128(2):225-31. doi: 10.1242/jcs.158451. Epub 2014 Nov 20.

12.

Identification of two novel loss-of-function SIM1 mutations in two overweight children with developmental delay.

Montagne L, Raimondo A, Delobel B, Duban-Bedu B, Noblet FS, Dechaume A, Bersten DC, Meyre D, Whitelaw ML, Froguel P, Bonnefond A.

Obesity (Silver Spring). 2014 Dec;22(12):2621-4. doi: 10.1002/oby.20886. Epub 2014 Sep 19.

13.

Restrictive eating disorders among adolescent inpatients.

Whitelaw M, Gilbertson H, Lee KJ, Sawyer SM.

Pediatrics. 2014 Sep;134(3):e758-64. doi: 10.1542/peds.2014-0070.

PMID:
25157005
14.

Characterization of human variants in obesity-related SIM1 protein identifies a hot-spot for dimerization with the partner protein ARNT2.

Sullivan AE, Raimondo A, Schwab TA, Bruning JB, Froguel P, Farooqi IS, Peet DJ, Whitelaw ML.

Biochem J. 2014 Aug 1;461(3):403-12. doi: 10.1042/BJ20131618.

PMID:
24814368
15.

Human variants in the neuronal basic helix-loop-helix/Per-Arnt-Sim (bHLH/PAS) transcription factor complex NPAS4/ARNT2 disrupt function.

Bersten DC, Bruning JB, Peet DJ, Whitelaw ML.

PLoS One. 2014 Jan 17;9(1):e85768. doi: 10.1371/journal.pone.0085768. eCollection 2014.

16.

Regulation of the neuronal transcription factor NPAS4 by REST and microRNAs.

Bersten DC, Wright JA, McCarthy PJ, Whitelaw ML.

Biochim Biophys Acta. 2014 Jan;1839(1):13-24. doi: 10.1016/j.bbagrm.2013.11.004. Epub 2013 Nov 28.

PMID:
24291638
17.

bHLH-PAS proteins in cancer.

Bersten DC, Sullivan AE, Peet DJ, Whitelaw ML.

Nat Rev Cancer. 2013 Dec;13(12):827-41. doi: 10.1038/nrc3621. Review.

PMID:
24263188
18.

Implementation of family-based treatment for adolescents with anorexia nervosa.

Hughes EK, Le Grange D, Court A, Yeo M, Campbell S, Whitelaw M, Atkins L, Sawyer SM.

J Pediatr Health Care. 2014 Jul-Aug;28(4):322-30. doi: 10.1016/j.pedhc.2013.07.012. Epub 2013 Sep 18.

PMID:
24055072
19.

The emerging roles of AhR in physiology and immunity.

Hao N, Whitelaw ML.

Biochem Pharmacol. 2013 Sep 1;86(5):561-70. doi: 10.1016/j.bcp.2013.07.004. Epub 2013 Jul 12.

PMID:
23856287
20.

Rare variants in single-minded 1 (SIM1) are associated with severe obesity.

Ramachandrappa S, Raimondo A, Cali AM, Keogh JM, Henning E, Saeed S, Thompson A, Garg S, Bochukova EG, Brage S, Trowse V, Wheeler E, Sullivan AE, Dattani M, Clayton PE, Datta V, Bruning JB, Wareham NJ, O'Rahilly S, Peet DJ, Barroso I, Whitelaw ML, Farooqi IS.

J Clin Invest. 2013 Jul;123(7):3042-50. doi: 10.1172/JCI68016. Epub 2013 Jun 17. Erratum in: J Clin Invest. 2013 Aug 1;123(8):3635. Datta, Vippan [corrected to Datta, Vipan].

21.

Loss-of-function mutations in SIM1 contribute to obesity and Prader-Willi-like features.

Bonnefond A, Raimondo A, Stutzmann F, Ghoussaini M, Ramachandrappa S, Bersten DC, Durand E, Vatin V, Balkau B, Lantieri O, Raverdy V, Pattou F, Van Hul W, Van Gaal L, Peet DJ, Weill J, Miller JL, Horber F, Goldstone AP, Driscoll DJ, Bruning JB, Meyre D, Whitelaw ML, Froguel P.

J Clin Invest. 2013 Jul;123(7):3037-41. doi: 10.1172/JCI68035. Epub 2013 Jun 17.

22.

Reciprocal regulation of the basic helix-loop-helix/Per-Arnt-Sim partner proteins, Arnt and Arnt2, during neuronal differentiation.

Hao N, Bhakti VL, Peet DJ, Whitelaw ML.

Nucleic Acids Res. 2013 Jun;41(11):5626-38. doi: 10.1093/nar/gkt206. Epub 2013 Apr 17.

23.

Dizziness and bradycardia for investigation.

Whitelaw M, Gilbertson H, Lee KJ, Sawyer SM.

Adolesc Med State Art Rev. 2012 Aug;23(2):381-6. Review. No abstract available.

PMID:
23162947
24.

Xenobiotics and loss of cell adhesion drive distinct transcriptional outcomes by aryl hydrocarbon receptor signaling.

Hao N, Lee KL, Furness SG, Bosdotter C, Poellinger L, Whitelaw ML.

Mol Pharmacol. 2012 Dec;82(6):1082-93. doi: 10.1124/mol.112.078873. Epub 2012 Aug 30.

PMID:
22936816
25.

NRF2 activation restores disease related metabolic deficiencies in olfactory neurosphere-derived cells from patients with sporadic Parkinson's disease.

Cook AL, Vitale AM, Ravishankar S, Matigian N, Sutherland GT, Shan J, Sutharsan R, Perry C, Silburn PA, Mellick GD, Whitelaw ML, Wells CA, Mackay-Sim A, Wood SA.

PLoS One. 2011;6(7):e21907. doi: 10.1371/journal.pone.0021907. Epub 2011 Jul 1.

26.

Identification of residues in the N-terminal PAS domains important for dimerization of Arnt and AhR.

Hao N, Whitelaw ML, Shearwin KE, Dodd IB, Chapman-Smith A.

Nucleic Acids Res. 2011 May;39(9):3695-709. doi: 10.1093/nar/gkq1336. Epub 2011 Jan 17.

27.

Does aggressive refeeding in hospitalized adolescents with anorexia nervosa result in increased hypophosphatemia?

Whitelaw M, Gilbertson H, Lam PY, Sawyer SM.

J Adolesc Health. 2010 Jun;46(6):577-82. doi: 10.1016/j.jadohealth.2009.11.207. Epub 2010 Jan 25.

PMID:
20472215
28.

Amino acid substitutions in the aryl hydrocarbon receptor ligand binding domain reveal YH439 as an atypical AhR activator.

Whelan F, Hao N, Furness SG, Whitelaw ML, Chapman-Smith A.

Mol Pharmacol. 2010 Jun;77(6):1037-46. doi: 10.1124/mol.109.062927. Epub 2010 Mar 15.

PMID:
20231332
29.

The HIF1alpha-inducible pro-cell death gene BNIP3 is a novel target of SIM2s repression through cross-talk on the hypoxia response element.

Farrall AL, Whitelaw ML.

Oncogene. 2009 Oct 15;28(41):3671-80. doi: 10.1038/onc.2009.228. Epub 2009 Aug 10.

PMID:
19668230
30.

The precautionary principle: what is the risk of reusing disposable drops in routine ophthalmology consultations and what are the costs of reducing this risk to zero?

Somner JE, Cavanagh DJ, Wong KK, Whitelaw M, Thomson T, Mansfield D.

Eye (Lond). 2010 Feb;24(2):361-3. doi: 10.1038/eye.2009.129. Epub 2009 Jun 12.

PMID:
19521427
31.

Sulfonation and phosphorylation of regions of the dioxin receptor susceptible to methionine modifications.

Dave KA, Whelan F, Bindloss C, Furness SG, Chapman-Smith A, Whitelaw ML, Gorman JJ.

Mol Cell Proteomics. 2009 Apr;8(4):706-19. doi: 10.1074/mcp.M800459-MCP200. Epub 2008 Dec 4.

32.

The bHLH/Per-Arnt-Sim transcription factor SIM2 regulates muscle transcript myomesin2 via a novel, non-canonical E-box sequence.

Woods S, Farrall A, Procko C, Whitelaw ML.

Nucleic Acids Res. 2008 Jun;36(11):3716-27. doi: 10.1093/nar/gkn247. Epub 2008 May 14.

33.

Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways.

Zheng X, Linke S, Dias JM, Zheng X, Gradin K, Wallis TP, Hamilton BR, Gustafsson M, Ruas JL, Wilkins S, Bilton RL, Brismar K, Whitelaw ML, Pereira T, Gorman JJ, Ericson J, Peet DJ, Lendahl U, Poellinger L.

Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3368-73. doi: 10.1073/pnas.0711591105. Epub 2008 Feb 25.

34.

The dioxin (aryl hydrocarbon) receptor as a model for adaptive responses of bHLH/PAS transcription factors.

Furness SG, Lees MJ, Whitelaw ML.

FEBS Lett. 2007 Jul 31;581(19):3616-25. Epub 2007 Apr 17. Review.

35.

Cell-specific regulation of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha stabilization and transactivation in a graded oxygen environment.

Bracken CP, Fedele AO, Linke S, Balrak W, Lisy K, Whitelaw ML, Peet DJ.

J Biol Chem. 2006 Aug 11;281(32):22575-85. Epub 2006 Jun 7.

36.

Novel DNA binding by a basic helix-loop-helix protein. The role of the dioxin receptor PAS domain.

Chapman-Smith A, Whitelaw ML.

J Biol Chem. 2006 May 5;281(18):12535-45. Epub 2006 Mar 6.

37.

Phosphorylation inhibits DNA-binding of alternatively spliced aryl hydrocarbon receptor nuclear translocator.

Kewley RJ, Whitelaw ML.

Biochem Biophys Res Commun. 2005 Dec 9;338(1):660-7. Epub 2005 Aug 19.

PMID:
16129408
38.

Activity of hypoxia-inducible factor 2alpha is regulated by association with the NF-kappaB essential modulator.

Bracken CP, Whitelaw ML, Peet DJ.

J Biol Chem. 2005 Apr 8;280(14):14240-51. Epub 2005 Jan 13.

39.

Proceedings of the Oxygen Homeostasis/Hypoxia Meeting.

Kaufman B, Scharf O, Arbeit J, Ashcroft M, Brown JM, Bruick RK, Chapman JD, Evans SM, Giaccia AJ, Harris AL, Huang E, Johnson R, Kaelin W Jr, Koch CJ, Maxwell P, Mitchell J, Neckers L, Powis G, Rajendran J, Semenza GL, Simons J, Storkebaum E, Welch MJ, Whitelaw M, Melillo G, Ivy SP.

Cancer Res. 2004 May 1;64(9):3350-6. No abstract available.

40.

Oxygen-dependent asparagine hydroxylation.

Peet DJ, Lando D, Whelan DA, Whitelaw ML, Gorman JJ.

Methods Enzymol. 2004;381:467-87. No abstract available.

PMID:
15063693
41.

Regulation of gene expression by the hypoxia-inducible factors.

Fedele AO, Whitelaw ML, Peet DJ.

Mol Interv. 2002 Jul;2(4):229-43. Review.

PMID:
14993394
42.

Substrate requirements of the oxygen-sensing asparaginyl hydroxylase factor-inhibiting hypoxia-inducible factor.

Linke S, Stojkoski C, Kewley RJ, Booker GW, Whitelaw ML, Peet DJ.

J Biol Chem. 2004 Apr 2;279(14):14391-7. Epub 2004 Jan 20.

43.

The mammalian basic helix-loop-helix/PAS family of transcriptional regulators.

Kewley RJ, Whitelaw ML, Chapman-Smith A.

Int J Biochem Cell Biol. 2004 Feb;36(2):189-204. Review.

PMID:
14643885
44.

Contribution of the Per/Arnt/Sim (PAS) domains to DNA binding by the basic helix-loop-helix PAS transcriptional regulators.

Chapman-Smith A, Lutwyche JK, Whitelaw ML.

J Biol Chem. 2004 Feb 13;279(7):5353-62. Epub 2003 Nov 24.

45.

The hypoxia-inducible factors: key transcriptional regulators of hypoxic responses.

Bracken CP, Whitelaw ML, Peet DJ.

Cell Mol Life Sci. 2003 Jul;60(7):1376-93. Review.

PMID:
12943226
46.

Defining the role for XAP2 in stabilization of the dioxin receptor.

Lees MJ, Peet DJ, Whitelaw ML.

J Biol Chem. 2003 Sep 19;278(38):35878-88. Epub 2003 Jul 1.

47.

Oxygen-dependent regulation of hypoxia-inducible factors by prolyl and asparaginyl hydroxylation.

Lando D, Gorman JJ, Whitelaw ML, Peet DJ.

Eur J Biochem. 2003 Mar;270(5):781-90. Review.

48.

Effect of ARA9 on dioxin receptor mediated transcription.

Lees MJ, Whitelaw ML.

Toxicology. 2002 Dec 27;181-182:143-6. Review.

PMID:
12505299
49.

Use of [125I]4'-iodoflavone as a tool to characterize ligand-dependent differences in Ah receptor behavior.

Swanson HI, Whitelaw ML, Petrulis JR, Perdew GH.

J Biochem Mol Toxicol. 2002;16(6):298-310.

PMID:
12481305
50.

A constitutively active dioxin/aryl hydrocarbon receptor induces stomach tumors.

Andersson P, McGuire J, Rubio C, Gradin K, Whitelaw ML, Pettersson S, Hanberg A, Poellinger L.

Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):9990-5. Epub 2002 Jul 9.

Supplemental Content

Loading ...
Support Center