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The association between pathogen factors and clinical outcomes in patients with Staphylococcus aureus bacteraemia in a tertiary hospital, Cape Town.

Abdulgader SM, van Rijswijk A, Whitelaw A, Newton-Foot M.

Int J Infect Dis. 2019 Nov 29. pii: S1201-9712(19)30472-2. doi: 10.1016/j.ijid.2019.11.032. [Epub ahead of print]


Clonal expansion of colistin resistant Acinetobacter baumannii isolates in Cape Town, South Africa.

Snyman Y, Whitelaw AC, Reuter S, Dramowski A, Maloba MRB, Newton-Foot M.

Int J Infect Dis. 2019 Nov 22. pii: S1201-9712(19)30460-6. doi: 10.1016/j.ijid.2019.11.021. [Epub ahead of print]


Multiple introductions of methicillin-resistant Staphylococcus aureus ST612 into Western Australia associated both with human and equine reservoirs.

Murphy RJT, Ramsay JP, Lee YT, Pang S, O'Dea MA, Pearson JC, Axon JE, Raby E, Abdulgader SM, Whitelaw A, Coombs GW.

Int J Antimicrob Agents. 2019 Dec;54(6):681-685. doi: 10.1016/j.ijantimicag.2019.08.022. Epub 2019 Aug 31.


Towards understanding global patterns of antimicrobial use and resistance in neonatal sepsis: insights from the NeoAMR network.

Li G, Bielicki JA, Ahmed ASMNU, Islam MS, Berezin EN, Gallacci CB, Guinsburg R, da Silva Figueiredo CE, Santarone Vieira R, Silva AR, Teixeira C, Turner P, Nhan L, Orrego J, Pérez PM, Qi L, Papaevangelou V, Triantafyllidou P, Iosifidis E, Roilides E, Sarafidis K, Jinka DR, Nayakanti RR, Kumar P, Gautam V, Prakash V, Seeralar A, Murki S, Kandraju H, Singh S, Kumar A, Lewis L, Pukayastha J, Nangia S, K N Y, Chaurasia S, Chellani H, Obaro S, Dramowski A, Bekker A, Whitelaw A, Thomas R, Velaphi SC, Ballot DE, Nana T, Reubenson G, Fredericks J, Anugulruengkitt S, Sirisub A, Wong P, Lochindarat S, Boonkasidecha S, Preedisripipat K, Cressey TR, Paopongsawan P, Lumbiganon P, Pongpanut D, Sukrakanchana PO, Musoke P, Olson L, Larsson M, Heath PT, Sharland M.

Arch Dis Child. 2019 Aug 24. pii: archdischild-2019-316816. doi: 10.1136/archdischild-2019-316816. [Epub ahead of print]


Assessment of Brain Injury and Brain Volumes after Posthemorrhagic Ventricular Dilatation: A Nested Substudy of the Randomized Controlled ELVIS Trial.

Cizmeci MN, Khalili N, Claessens NHP, Groenendaal F, Liem KD, Heep A, Benavente-Fernández I, van Straaten HLM, van Wezel-Meijler G, Steggerda SJ, Dudink J, Išgum I, Whitelaw A, Benders MJNL, de Vries LS; ELVIS study group.

J Pediatr. 2019 May;208:191-197.e2. doi: 10.1016/j.jpeds.2018.12.062. Epub 2019 Mar 14.


Ten-year follow-up of a randomised trial of drainage, irrigation and fibrinolytic therapy (DRIFT) in infants with post-haemorrhagic ventricular dilatation.

Luyt K, Jary S, Lea C, Young GJ, Odd D, Miller H, Kmita G, Williams C, Blair PS, Fernández AM, Hollingworth W, Morgan M, Smith-Collins A, Thai NJ, Walker-Cox S, Aquilina K, Pople I, Whitelaw A.

Health Technol Assess. 2019 Feb;23(4):1-116. doi: 10.3310/hta23040.


Specimen Pooling as a Diagnostic Strategy for Microbiologic Confirmation in Children with Intrathoracic Tuberculosis.

Walters E, van der Zalm MM, Demers AM, Whitelaw A, Palmer M, Bosch C, Draper HR, Schaaf HS, Goussard P, Lombard CJ, Gie RP, Hesseling AC.

Pediatr Infect Dis J. 2019 Jun;38(6):e128-e131. doi: 10.1097/INF.0000000000002240.


Parent report on quality of life in post-haemorrhagic hydrocephalus.

Whitelaw A.

Dev Med Child Neurol. 2019 Mar;61(3):288. doi: 10.1111/dmcn.14074. Epub 2018 Oct 15. No abstract available.


Erratum to South African guideline for the management of community-acquired pneumonia in adults.

Boyles TH, Brink A, Calligaro GL, Cohen C, Dheda K, Maartens G, Richards GA, van Zyl Smit R, Smith C, Wasserman S, Whitelaw AC, Feldman C; South African Thoracic Society; Federation of Infectious Diseases Societies of Southern Africa.

J Thorac Dis. 2018 Aug;10(8):E673-E675. doi: 10.21037/jtd.2018.07.137.


Paediatric antimicrobial use at a South African hospital.

Koopmans LR, Finlayson H, Whitelaw A, Decloedt EH, Dramowski A.

Int J Infect Dis. 2018 Sep;74:16-23. doi: 10.1016/j.ijid.2018.05.020. Epub 2018 Jun 20.


Reply to Drancourt, "Culturing Stools To Detect Mycobacterium tuberculosis".

Walters E, Demers AM, van der Zalm MM, Whitelaw A, Palmer M, Bosch C, Draper HR, Gie RP, Hesseling AC.

J Clin Microbiol. 2018 Apr 25;56(5). pii: e00056-18. doi: 10.1128/JCM.00056-18. Print 2018 May. No abstract available.


A moment for compassion: emerging rhetorics in end-of-life care.

Zaman S, Whitelaw A, Richards N, Inbadas H, Clark D.

Med Humanit. 2018 Jun;44(2):140-143. doi: 10.1136/medhum-2017-011329. Epub 2018 Feb 10.


Treatment thresholds for intervention in posthaemorrhagic ventricular dilation: a randomised controlled trial.

de Vries LS, Groenendaal F, Liem KD, Heep A, Brouwer AJ, van 't Verlaat E, Benavente-Fernández I, van Straaten HL, van Wezel-Meijler G, Smit BJ, Govaert P, Woerdeman PA, Whitelaw A; ELVIS study group.

Arch Dis Child Fetal Neonatal Ed. 2019 Jan;104(1):F70-F75. doi: 10.1136/archdischild-2017-314206. Epub 2018 Feb 10.


Neonatal and paediatric bloodstream infections: Pathogens, antimicrobial resistance patterns and prescribing practice at Khayelitsha District Hospital, Cape Town, South Africa.

Crichton H, O'Connell N, Rabie H, Whitelaw AC, Dramowski A.

S Afr Med J. 2018 Feb 1;108(2):99-104. doi: 10.7196/SAMJ.2017.v108i2.12601.


Stool Culture for Diagnosis of Pulmonary Tuberculosis in Children.

Walters E, Demers AM, van der Zalm MM, Whitelaw A, Palmer M, Bosch C, Draper HR, Gie RP, Hesseling AC.

J Clin Microbiol. 2017 Dec;55(12):3355-3365. doi: 10.1128/JCM.00801-17. Epub 2017 Sep 13.


A small proportion of community-associated methicillin-resistant Staphylococcus aureus bacteraemia, compared to healthcare-associated cases, in two South African provinces.

Perovic O, Singh-Moodley A, Govender NP, Kularatne R, Whitelaw A, Chibabhai V, Naicker P, Mbelle N, Lekalakala R, Quan V, Samuel C, Van Schalkwyk E; for GERMS-SA.

Eur J Clin Microbiol Infect Dis. 2017 Dec;36(12):2519-2532. doi: 10.1007/s10096-017-3096-3. Epub 2017 Aug 28.


Plasmid-mediated mcr-1 colistin resistance in Escherichia coli and Klebsiella spp. clinical isolates from the Western Cape region of South Africa.

Newton-Foot M, Snyman Y, Maloba MRB, Whitelaw AC.

Antimicrob Resist Infect Control. 2017 Aug 3;6:78. doi: 10.1186/s13756-017-0234-8. eCollection 2017.


South African guideline for the management of community-acquired pneumonia in adults.

Boyles TH, Brink A, Calligaro GL, Cohen C, Dheda K, Maartens G, Richards GA, van Zyl Smit R, Smith C, Wasserman S, Whitelaw AC, Feldman C; South African Thoracic Society; Federation of Infectious Diseases Societies of Southern Africa.

J Thorac Dis. 2017 Jun;9(6):1469-1502. doi: 10.21037/jtd.2017.05.31. Review. No abstract available. Erratum in: J Thorac Dis. 2018 Aug;10(8):E673-E675.


Repeated lumbar or ventricular punctures in newborns with intraventricular haemorrhage.

Whitelaw A, Lee-Kelland R.

Cochrane Database Syst Rev. 2017 Apr 6;4:CD000216. doi: 10.1002/14651858.CD000216.pub2. Review.


A framework for preventing healthcare-associated infection in neonates and children in South Africa.

Dramowski A, Cotton MF, Whitelaw A.

S Afr Med J. 2017 Feb 27;107(3):192-195. doi: 10.7196/SAMJ.2017.v107i3.12035.


Xpert MTB/RIF on Stool Is Useful for the Rapid Diagnosis of Tuberculosis in Young Children With Severe Pulmonary Disease.

Walters E, van der Zalm MM, Palmer M, Bosch C, Demers AM, Draper H, Goussard P, Schaaf HS, Friedrich SO, Whitelaw A, Warren R, Gie RP, Hesseling AC.

Pediatr Infect Dis J. 2017 Sep;36(9):837-843. doi: 10.1097/INF.0000000000001563.


Surveillance of healthcare-associated infection in hospitalised South African children: Which method performs best?

Dramowski A, Cotton MF, Whitelaw A.

S Afr Med J. 2016 Dec 21;107(1):56-63. doi: 10.7196/SAMJ.2016.v107.i1.11431.


Common or multiple futures for end of life care around the world? Ideas from the 'waiting room of history'.

Zaman S, Inbadas H, Whitelaw A, Clark D.

Soc Sci Med. 2017 Jan;172:72-79. doi: 10.1016/j.socscimed.2016.11.012. Epub 2016 Nov 9. Review.


The Cape Town Clinical Decision Rule for Streptococcal Pharyngitis in Children.

Engel ME, Cohen K, Gounden R, Kengne AP, Barth DD, Whitelaw AC, Francis V, Badri M, Stewart A, Dale JB, Mayosi BM, Maartens G.

Pediatr Infect Dis J. 2017 Mar;36(3):250-255. doi: 10.1097/INF.0000000000001413.


Burden, spectrum, and impact of healthcare-associated infection at a South African children's hospital.

Dramowski A, Whitelaw A, Cotton MF.

J Hosp Infect. 2016 Dec;94(4):364-372. doi: 10.1016/j.jhin.2016.08.022. Epub 2016 Sep 1.


Molecular characterization of Staphylococcus aureus isolates from various healthcare institutions in Nairobi, Kenya: a cross sectional study.

Omuse G, Van Zyl KN, Hoek K, Abdulgader S, Kariuki S, Whitelaw A, Revathi G.

Ann Clin Microbiol Antimicrob. 2016 Sep 20;15(1):51. doi: 10.1186/s12941-016-0171-z.


Assessment of terminal cleaning in pediatric isolation rooms: Options for low-resource settings.

Dramowski A, Whitelaw A, Cotton MF.

Am J Infect Control. 2016 Dec 1;44(12):1558-1564. doi: 10.1016/j.ajic.2016.05.026. Epub 2016 Aug 22.


Palliative Care Declarations: Mapping a New Form of Intervention.

Inbadas H, Zaman S, Whitelaw A, Clark D.

J Pain Symptom Manage. 2016 Sep;52(3):e7-e15. doi: 10.1016/j.jpainsymman.2016.05.009. Epub 2016 Jul 9. No abstract available.


Emergence of azole-resistant Candida parapsilosis causing bloodstream infection: results from laboratory-based sentinel surveillance in South Africa.

Govender NP, Patel J, Magobo RE, Naicker S, Wadula J, Whitelaw A, Coovadia Y, Kularatne R, Govind C, Lockhart SR, Zietsman IL; TRAC-South Africa group.

J Antimicrob Chemother. 2016 Jul;71(7):1994-2004. doi: 10.1093/jac/dkw091. Epub 2016 Apr 28.


Promotion of alleles by genome editing in livestock breeding programmes.

Hickey JM, Bruce C, Whitelaw A, Gorjanc G.

J Anim Breed Genet. 2016 Apr;133(2):83-4. doi: 10.1111/jbg.12206. No abstract available.


Rationale and design of the African group A streptococcal infection registry: the AFROStrep study.

Barth DD, Engel ME, Whitelaw A, Abdissa A, Sadoh WE, Ali SK, Sow SO, Dale J, Mayosi BM.

BMJ Open. 2016 Feb 25;6(2):e010248. doi: 10.1136/bmjopen-2015-010248. Erratum in: BMJ Open. 2016 May 23;6(5):e010248corr1.


A comparison of Clostridium difficile diagnostic methods for identification of local strains in a South African centre.

Rajabally N, Kullin B, Ebrahim K, Brock T, Weintraub A, Whitelaw A, Bamford C, Watermeyer G, Thomson S, Abratt V, Reid S.

J Med Microbiol. 2016 Apr;65(4):320-327. doi: 10.1099/jmm.0.000231. Epub 2016 Feb 9.


Time for a culture change? Suboptimal compliance with blood culture standards at a district hospital in Cape Town.

Abrahams MS, Whitelaw AC, Orth H.

S Afr Med J. 2015 Nov 6;105(12):1039-43. doi: 10.7196/SAMJ.2015.v105i12.9442.


Clinical implications of molecular drug resistance testing for Mycobacterium tuberculosis: a TBNET/RESIST-TB consensus statement.

Domínguez J, Boettger EC, Cirillo D, Cobelens F, Eisenach KD, Gagneux S, Hillemann D, Horsburgh R, Molina-Moya B, Niemann S, Tortoli E, Whitelaw A, Lange C; TBNET; RESIST-TB networks.

Int J Tuberc Lung Dis. 2016 Jan;20(1):24-42. doi: 10.5588/ijtld.15.0221. Review.


Utilization of paediatric isolation facilities in a TB-endemic setting.

Dramowski A, Cotton MF, Whitelaw A.

Antimicrob Resist Infect Control. 2015 Sep 21;4:36. doi: 10.1186/s13756-015-0078-z. eCollection 2015.


The utility of Xpert MTB/RIF performed on bronchial washings obtained in patients with suspected pulmonary tuberculosis in a high prevalence setting.

Barnard DA, Irusen EM, Bruwer JW, Plekker D, Whitelaw AC, Deetlefs JD, Koegelenberg CF.

BMC Pulm Med. 2015 Sep 16;15:103. doi: 10.1186/s12890-015-0086-z.


Role of infection control in combating antibiotic resistance.

Whitelaw AC.

S Afr Med J. 2015 Apr 10;105(5):421. doi: 10.7196/samj.9650.


Prevalence of gastrointestinal pathogenic bacteria in patients with diarrhoea attending Groote Schuur Hospital, Cape Town, South Africa.

Kullin B, Meggersee R, D'Alton J, Galvao B, Rajabally N, Whitelaw A, Bamford C, Reid SJ, Abratt VR.

S Afr Med J. 2015 Jan 5;105(2):121-5. doi: 10.7196/samj.8654.


Maternal Colonization with Group B Streptococcus Is Associated with an Increased Rate of Infants Transferred to the Neonatal Intensive Care Unit.

Brigtsen AK, Jacobsen AF, Dedi L, Melby KK, Fugelseth D, Whitelaw A.

Neonatology. 2015;108(3):157-63. doi: 10.1159/000434716. Epub 2015 Jul 11.


Two-stage activity-safety study of daily rifapentine during intensive phase treatment of pulmonary tuberculosis.

Dawson R, Narunsky K, Carman D, Gupte N, Whitelaw A, Efron A, Barnes GL, Hoffman J, Chaisson RE, McIlleron H, Dorman SE.

Int J Tuberc Lung Dis. 2015 Jul;19(7):780-6. doi: 10.5588/ijtld.14.0868.


Healthcare-associated infections in children: knowledge, attitudes and practice of paediatric healthcare providers at Tygerberg Hospital, Cape Town.

Dramowski A, Whitelaw A, Cotton MF.

Paediatr Int Child Health. 2016 Aug;36(3):225-31. doi: 10.1179/2046905515Y.0000000032.


The pros, cons, and unknowns of search and destroy for carbapenem-resistant enterobacteriaceae.

Moodley P, Whitelaw A.

Curr Infect Dis Rep. 2015 Jun;17(6):483. doi: 10.1007/s11908-015-0483-8.


Trends in paediatric bloodstream infections at a South African referral hospital.

Dramowski A, Cotton MF, Rabie H, Whitelaw A.

BMC Pediatr. 2015 Apr 2;15:33. doi: 10.1186/s12887-015-0354-3.


A complement C5 gene mutation, c.754G>A:p.A252T, is common in the Western Cape, South Africa and found to be homozygous in seven percent of Black African meningococcal disease cases.

Owen EP, Würzner R, Leisegang F, Rizkallah P, Whitelaw A, Simpson J, Thomas AD, Harris CL, Giles JL, Hellerud BC, Mollnes TE, Morgan BP, Potter PC, Orren A.

Mol Immunol. 2015 Mar;64(1):170-6. doi: 10.1016/j.molimm.2014.11.010. Epub 2014 Dec 19.


Comparison of PCR and serotyping of Group B Streptococcus in pregnant women: the Oslo GBS-study.

Brigtsen AK, Dedi L, Melby KK, Holberg-Petersen M, Radtke A, Lyng RV, Andresen LL, Jacobsen AF, Fugelseth D, Whitelaw A.

J Microbiol Methods. 2015 Jan;108:31-5. doi: 10.1016/j.mimet.2014.11.001. Epub 2014 Nov 13.


Impact of Xpert MTB/RIF for TB diagnosis in a primary care clinic with high TB and HIV prevalence in South Africa: a pragmatic randomised trial.

Cox HS, Mbhele S, Mohess N, Whitelaw A, Muller O, Zemanay W, Little F, Azevedo V, Simpson J, Boehme CC, Nicol MP.

PLoS Med. 2014 Nov 25;11(11):e1001760. doi: 10.1371/journal.pmed.1001760. eCollection 2014 Nov.


Reply to Yates et al.

Middelkoop K, Mathema B, Whitelaw A, Bekker LG, Wood R.

J Infect Dis. 2015 May 1;211(9):1510-1. doi: 10.1093/infdis/jiu629. Epub 2014 Nov 11. No abstract available.


National sentinel site surveillance for antimicrobial resistance in Klebsiella pneumoniae isolates in South Africa, 2010 - 2012.

Perovic O, Singh-Moodley A, Dusé A, Bamford C, Elliott G, Swe-Han KS, Kularatne R, Lowman W, Whitelaw A, Nana T, Wadula J, Lekalakala R, Saif A, Fortuin De-Smit M, Marais E.

S Afr Med J. 2014 Jun 19;104(8):563-8. doi: 10.7196/samj.7617.


Transmission of tuberculosis in a South African community with a high prevalence of HIV infection.

Middelkoop K, Mathema B, Myer L, Shashkina E, Whitelaw A, Kaplan G, Kreiswirth B, Wood R, Bekker LG.

J Infect Dis. 2015 Jan 1;211(1):53-61. doi: 10.1093/infdis/jiu403. Epub 2014 Jul 22.


A controlled trial of sputum induction and routine collection methods for TB diagnosis in a South African community.

Geldenhuys HD, Whitelaw A, Tameris MD, Van As D, Luabeya KK, Mahomed H, Hussey G, Hanekom WA, Hatherill M.

Eur J Clin Microbiol Infect Dis. 2014 Dec;33(12):2259-66. doi: 10.1007/s10096-014-2198-4. Epub 2014 Jul 15.

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