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Items: 1 to 50 of 157

1.

Establishment of novel in vitro mouse chief cell and SPEM cultures identifies MAL2 as a marker of metaplasia in the stomach.

Weis VG, Petersen CP, Mills JC, Tuma PL, Whitehead RH, Goldenring JR.

Am J Physiol Gastrointest Liver Physiol. 2014 Oct 15;307(8):G777-92. doi: 10.1152/ajpgi.00169.2014. Epub 2014 Sep 4.

2.

Lineage-specific RUNX3 hypomethylation marks the preneoplastic immune component of gastric cancer.

Kurklu B, Whitehead RH, Ong EK, Minamoto T, Fox JG, Mann JR, Judd LM, Giraud AS, Menheniott TR.

Oncogene. 2015 May 28;34(22):2856-66. doi: 10.1038/onc.2014.233. Epub 2014 Aug 4.

3.

Remarks on the outbreak of cholera in Broad Street, Golden Square, London, in 1854.

Whitehead RH.

Int J Epidemiol. 2014 Apr;43(2):597-9. No abstract available.

PMID:
24877172
4.

Fibrogenesis in pancreatic cancer is a dynamic process regulated by macrophage-stellate cell interaction.

Shi C, Washington MK, Chaturvedi R, Drosos Y, Revetta FL, Weaver CJ, Buzhardt E, Yull FE, Blackwell TS, Sosa-Pineda B, Whitehead RH, Beauchamp RD, Wilson KT, Means AL.

Lab Invest. 2014 Apr;94(4):409-21. doi: 10.1038/labinvest.2014.10. Epub 2014 Feb 17.

5.

Malignant transformation of colonic epithelial cells by a colon-derived long noncoding RNA.

Franklin JL, Rankin CR, Levy S, Snoddy JR, Zhang B, Washington MK, Thomson JM, Whitehead RH, Coffey RJ.

Biochem Biophys Res Commun. 2013 Oct 11;440(1):99-104. doi: 10.1016/j.bbrc.2013.09.040. Epub 2013 Sep 14.

6.

Myofibroblast keratinocyte growth factor reduces tight junctional integrity and increases claudin-2 levels in polarized Caco-2 cells.

Kim TI, Poulin EJ, Blask E, Bukhalid R, Whitehead RH, Franklin JL, Coffey RJ.

Growth Factors. 2012 Oct;30(5):320-32. Epub 2012 Sep 5.

7.

Epidermal growth factor receptor regulates pancreatic fibrosis.

Blaine SA, Ray KC, Branch KM, Robinson PS, Whitehead RH, Means AL.

Am J Physiol Gastrointest Liver Physiol. 2009 Sep;297(3):G434-41. doi: 10.1152/ajpgi.00152.2009. Epub 2009 Jul 16.

8.

Simian virus 40 T-antigen-mediated gene regulation in enterocytes is controlled primarily by the Rb-E2F pathway.

Rathi AV, Sáenz Robles MT, Cantalupo PG, Whitehead RH, Pipas JM.

J Virol. 2009 Sep;83(18):9521-31. doi: 10.1128/JVI.00583-09. Epub 2009 Jul 1.

9.

Selective inhibition of proliferation in colorectal carcinoma cell lines expressing mutant APC or activated B-Raf.

Zhang HH, Walker F, Kiflemariam S, Whitehead RH, Williams D, Phillips WA, Mikeska T, Dobrovic A, Burgess AW.

Int J Cancer. 2009 Jul 15;125(2):297-307. doi: 10.1002/ijc.24289.

10.

Cell-type specific regulation of gene expression by simian virus 40 T antigens.

Cantalupo PG, Sáenz-Robles MT, Rathi AV, Beerman RW, Patterson WH, Whitehead RH, Pipas JM.

Virology. 2009 Mar 30;386(1):183-91. doi: 10.1016/j.virol.2008.12.038. Epub 2009 Feb 8.

11.

Identification of early intestinal neoplasia protein biomarkers using laser capture microdissection and MALDI MS.

Xu BJ, Li J, Beauchamp RD, Shyr Y, Li M, Washington MK, Yeatman TJ, Whitehead RH, Coffey RJ, Caprioli RM.

Mol Cell Proteomics. 2009 May;8(5):936-45. doi: 10.1074/mcp.M800345-MCP200. Epub 2009 Jan 21.

12.

Unlike esophageal squamous cells, Barrett's epithelial cells resist apoptosis by activating the nuclear factor-kappaB pathway.

Hormi-Carver K, Zhang X, Zhang HY, Whitehead RH, Terada LS, Spechler SJ, Souza RF.

Cancer Res. 2009 Jan 15;69(2):672-7. doi: 10.1158/0008-5472.CAN-08-3703.

13.

Establishment of conditionally immortalized epithelial cell lines from the intestinal tissue of adult normal and transgenic mice.

Whitehead RH, Robinson PS.

Am J Physiol Gastrointest Liver Physiol. 2009 Mar;296(3):G455-60. doi: 10.1152/ajpgi.90381.2008. Epub 2008 Dec 24. Review.

14.

Analysis of Wnt/FZD-mediated signalling in a cell line model of colorectal cancer morphogenesis.

Vincan E, Whitehead RH, Faux MC.

Methods Mol Biol. 2008;468:263-73. doi: 10.1007/978-1-59745-249-6_21.

PMID:
19099262
15.

Conditionally immortalized colonic epithelial cell line from a Ptk6 null mouse that polarizes and differentiates in vitro.

Whitehead RH, Robinson PS, Williams JA, Bie W, Tyner AL, Franklin JL.

J Gastroenterol Hepatol. 2008 Jul;23(7 Pt 1):1119-24. doi: 10.1111/j.1440-1746.2008.05308.x. Epub 2008 Jan 19.

16.

Epidermal growth factor stimulates Rac activation through Src and phosphatidylinositol 3-kinase to promote colonic epithelial cell migration.

Dise RS, Frey MR, Whitehead RH, Polk DB.

Am J Physiol Gastrointest Liver Physiol. 2008 Jan;294(1):G276-85. Epub 2007 Nov 8.

17.

Intestinal hyperplasia induced by simian virus 40 large tumor antigen requires E2F2.

Sáenz-Robles MT, Markovics JA, Chong JL, Opavsky R, Whitehead RH, Leone G, Pipas JM.

J Virol. 2007 Dec;81(23):13191-9. Epub 2007 Sep 12.

18.

Oncogenic K-RAS subverts the antiapoptotic role of N-RAS and alters modulation of the N-RAS:gelsolin complex.

Keller JW, Haigis KM, Franklin JL, Whitehead RH, Jacks T, Coffey RJ.

Oncogene. 2007 May 10;26(21):3051-9. Epub 2006 Nov 20.

PMID:
17130841
19.

Mtgr1 is a transcriptional corepressor that is required for maintenance of the secretory cell lineage in the small intestine.

Amann JM, Chyla BJ, Ellis TC, Martinez A, Moore AC, Franklin JL, McGhee L, Meyers S, Ohm JE, Luce KS, Ouelette AJ, Washington MK, Thompson MA, King D, Gautam S, Coffey RJ, Whitehead RH, Hiebert SW.

Mol Cell Biol. 2005 Nov;25(21):9576-85.

20.

Gene expression profile analysis of mouse colon embryonic development.

Park YK, Franklin JL, Settle SH, Levy SE, Chung E, Jeyakumar LH, Shyr Y, Washington MK, Whitehead RH, Aronow BJ, Coffey RJ.

Genesis. 2005 Jan;41(1):1-12.

PMID:
15645444
21.

Smad3 has a critical role in TGF-beta-mediated growth inhibition and apoptosis in colonic epithelial cells.

Mithani SK, Balch GC, Shiou SR, Whitehead RH, Datta PK, Beauchamp RD.

J Surg Res. 2004 Apr;117(2):296-305.

PMID:
15047135
22.

Over-expression of cyclin D1 regulates Cdk4 protein synthesis.

Parker MA, Deane NG, Thompson EA, Whitehead RH, Mithani SK, Washington MK, Datta PK, Dixon DA, Beauchamp RD.

Cell Prolif. 2003 Dec;36(6):347-60.

PMID:
14710852
23.

Stimulated shedding of vascular cell adhesion molecule 1 (VCAM-1) is mediated by tumor necrosis factor-alpha-converting enzyme (ADAM 17).

Garton KJ, Gough PJ, Philalay J, Wille PT, Blobel CP, Whitehead RH, Dempsey PJ, Raines EW.

J Biol Chem. 2003 Sep 26;278(39):37459-64. Epub 2003 Jul 23.

24.

Stromal production of prostacyclin confers an antiapoptotic effect to colonic epithelial cells.

Cutler NS, Graves-Deal R, LaFleur BJ, Gao Z, Boman BM, Whitehead RH, Terry E, Morrow JD, Coffey RJ.

Cancer Res. 2003 Apr 15;63(8):1748-51.

25.

Overexpression of heparin-binding EGF-like growth factor in mouse pancreas results in fibrosis and epithelial metaplasia.

Means AL, Ray KC, Singh AB, Washington MK, Whitehead RH, Harris RC Jr, Wright CV, Coffey RJ Jr, Leach SD.

Gastroenterology. 2003 Apr;124(4):1020-36.

PMID:
12671899
26.

Evidence of selection for clones having genetic inactivation of the activin A type II receptor (ACVR2) gene in gastrointestinal cancers.

Hempen PM, Zhang L, Bansal RK, Iacobuzio-Donahue CA, Murphy KM, Maitra A, Vogelstein B, Whitehead RH, Markowitz SD, Willson JK, Yeo CJ, Hruban RH, Kern SE.

Cancer Res. 2003 Mar 1;63(5):994-9.

27.

Identification and isolation of candidate human colonic clonogenic cells based on cell surface integrin expression.

Fujimoto K, Beauchamp RD, Whitehead RH.

Gastroenterology. 2002 Dec;123(6):1941-8.

PMID:
12454851
28.

The phosphatidylinositol 3'-kinase p85alpha gene is an oncogene in human ovarian and colon tumors.

Philp AJ, Campbell IG, Leet C, Vincan E, Rockman SP, Whitehead RH, Thomas RJ, Phillips WA.

Cancer Res. 2001 Oct 15;61(20):7426-9.

29.

Expression of interleukin-6, leukemia inhibitory factor and their receptors by colonic epithelium and pericryptal fibroblasts.

Rockman SP, Demmler K, Roczo N, Cosgriff A, Phillips WA, Thomas RJ, Whitehead RH.

J Gastroenterol Hepatol. 2001 Sep;16(9):991-1000.

PMID:
11595063
30.
31.

HGF regulates tight junctions in new nontumorigenic gastric epithelial cell line.

Hollande F, Blanc EM, Bali JP, Whitehead RH, Pelegrin A, Baldwin GS, Choquet A.

Am J Physiol Gastrointest Liver Physiol. 2001 May;280(5):G910-21.

32.

PMC42, a novel model for the differentiated human breast.

Ackland ML, Michalczyk A, Whitehead RH.

Exp Cell Res. 2001 Feb 1;263(1):14-22.

PMID:
11161701
33.

Conditionally immortalized mouse hepatocytes for use in liver gene therapy.

Allen KJ, Reyes R, Demmler K, Mercer JF, Williamson R, Whitehead RH.

J Gastroenterol Hepatol. 2000 Nov;15(11):1325-32.

PMID:
11129229
34.

Characterization of mouse A33 antigen, a definitive marker for basolateral surfaces of intestinal epithelial cells.

Johnstone CN, Tebbutt NC, Abud HE, White SJ, Stenvers KL, Hall NE, Cody SH, Whitehead RH, Catimel B, Nice EC, Burgess AW, Heath JK.

Am J Physiol Gastrointest Liver Physiol. 2000 Sep;279(3):G500-10.

35.

Clonogenic growth of epithelial cells from normal colonic mucosa from both mice and humans.

Whitehead RH, Demmler K, Rockman SP, Watson NK.

Gastroenterology. 1999 Oct;117(4):858-65.

PMID:
10500068
36.

c-Myb down-regulation is associated with human colon cell differentiation, apoptosis, and decreased Bcl-2 expression.

Thompson MA, Rosenthal MA, Ellis SL, Friend AJ, Zorbas MI, Whitehead RH, Ramsay RG.

Cancer Res. 1998 Nov 15;58(22):5168-75.

37.

Rapid diagnostic test for hereditary nonpolyposis colon cancer kindred using polymerase chain reaction.

Faragher IG, Whitehead RH.

Dis Colon Rectum. 1998 Jul;41(7):938-40.

PMID:
9678385
38.

Short-chain fatty acids inhibit intestinal trefoil factor gene expression in colon cancer cells.

Tran CP, Familari M, Parker LM, Whitehead RH, Giraud AS.

Am J Physiol. 1998 Jul;275(1):G85-94. doi: 10.1152/ajpgi.1998.275.1.G85.

PMID:
9655688
39.

The human A33 antigen is a transmembrane glycoprotein and a novel member of the immunoglobulin superfamily.

Heath JK, White SJ, Johnstone CN, Catimel B, Simpson RJ, Moritz RL, Tu GF, Ji H, Whitehead RH, Groenen LC, Scott AM, Ritter G, Cohen L, Welt S, Old LJ, Nice EC, Burgess AW.

Proc Natl Acad Sci U S A. 1997 Jan 21;94(2):469-74.

40.

Colonic expression of c-myb is initiated in utero and continues throughout adult life.

Rosenthal MA, Thompson MA, Ellis S, Whitehead RH, Ramsay RG.

Cell Growth Differ. 1996 Jul;7(7):961-7.

41.

Synergy between Apc min and an activated ras mutation is sufficient to induce colon carcinomas.

D'Abaco GM, Whitehead RH, Burgess AW.

Mol Cell Biol. 1996 Mar;16(3):884-91.

42.

Effects of vesicocolic anastomosis on the proliferation of colonic mucosa in a rat model.

Edwards WH, Whitehead RH.

Aust N Z J Surg. 1995 Sep;65(9):667-71.

PMID:
7575300
43.

Effect of TGF-beta on differentiated organoids of the colon carcinoma cell line LIM 1863.

Hayward IP, Whitehead RH, Ward L, Gianello R, Dempsey P, Bates R, Burns GF.

Immunol Cell Biol. 1995 Jun;73(3):249-57.

PMID:
7590899
44.

Keratinocyte growth factor induces proliferation of hepatocytes and epithelial cells throughout the rat gastrointestinal tract.

Housley RM, Morris CF, Boyle W, Ring B, Biltz R, Tarpley JE, Aukerman SL, Devine PL, Whitehead RH, Pierce GF.

J Clin Invest. 1994 Nov;94(5):1764-77.

46.

Two-dimensional electrophoretic analysis of proteins expressed by normal and cancerous human crypts: application of mass spectrometry to peptide-mass fingerprinting.

Ji H, Whitehead RH, Reid GE, Moritz RL, Ward LD, Simpson RJ.

Electrophoresis. 1994 Mar-Apr;15(3-4):391-405.

PMID:
8055868
47.

Gut hormones, growth and malignancy.

Baldwin GS, Whitehead RH.

Baillieres Clin Endocrinol Metab. 1994 Jan;8(1):185-214. Review.

PMID:
7907861
48.

Monoclonal antibodies reacting with the MUC2 mucin core protein.

Devine PL, McGuckin MA, Birrell GW, Whitehead RH, Sachdev GP, Shield P, Ward BG.

Br J Cancer. 1993 Jun;67(6):1182-8.

49.

Establishment of conditionally immortalized epithelial cell lines from both colon and small intestine of adult H-2Kb-tsA58 transgenic mice.

Whitehead RH, VanEeden PE, Noble MD, Ataliotis P, Jat PS.

Proc Natl Acad Sci U S A. 1993 Jan 15;90(2):587-91. Erratum in: Proc Natl Acad Sci U S A 1993 Jul 15;90(14):6894.

50.

Cell-surface fucosylation and magnetic resonance spectroscopy characterization of human malignant colorectal cells.

Lean CL, Mackinnon WB, Delikatny EJ, Whitehead RH, Mountford CE.

Biochemistry. 1992 Nov 17;31(45):11095-105.

PMID:
1445848

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