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Items: 1 to 50 of 119

1.

PAX7 target genes are globally repressed in facioscapulohumeral muscular dystrophy skeletal muscle.

Banerji CRS, Panamarova M, Hebaishi H, White RB, Relaix F, Severini S, Zammit PS.

Nat Commun. 2017 Dec 18;8(1):2152. doi: 10.1038/s41467-017-01200-4.

2.

Influence of antenatal glucocorticoid on preterm lamb diaphragm.

Mahzabin T, Pillow JJ, Pinniger GJ, Bakker AJ, Noble PB, White RB, Karisnan K, Song Y.

Pediatr Res. 2017 Sep;82(3):509-517. doi: 10.1038/pr.2017.99. Epub 2017 May 17.

PMID:
28388600
3.

Erratum to: Voluntary resistance wheel exercise from mid-life prevents sarcopenia and increases markers of mitochondrial function and autophagy in muscles of old male and female C57BL/6J mice.

White Z, Terrill J, White RB, McMahon C, Sheard P, Grounds MD, Shavlakadze T.

Skelet Muscle. 2017 Feb 15;7(1):4. doi: 10.1186/s13395-017-0120-3. No abstract available.

4.
5.

High mTORC1 signaling is maintained, while protein degradation pathways are perturbed in old murine skeletal muscles in the fasted state.

White Z, White RB, McMahon C, Grounds MD, Shavlakadze T.

Int J Biochem Cell Biol. 2016 Sep;78:10-21. doi: 10.1016/j.biocel.2016.06.012. Epub 2016 Jun 22.

PMID:
27343428
6.

Observation of Critical-Gradient Behavior in Alfvén-Eigenmode-Induced Fast-Ion Transport.

Collins CS, Heidbrink WW, Austin ME, Kramer GJ, Pace DC, Petty CC, Stagner L, Van Zeeland MA, White RB, Zhu YB; DIII-D team.

Phys Rev Lett. 2016 Mar 4;116(9):095001. doi: 10.1103/PhysRevLett.116.095001. Epub 2016 Feb 29.

7.

Developmental transcription factors in age-related CNS disease: a phoenix rising from the ashes?

White RB, Thomas MG.

Neural Regen Res. 2016 Jan;11(1):64-5. doi: 10.4103/1673-5374.175044. No abstract available.

8.

PAX6 expression may be protective against dopaminergic cell loss in Parkinson's disease.

Thomas MG, Welch C, Stone L, Allan P, Barker RA, White RB.

CNS Neurol Disord Drug Targets. 2016;15(1):73-9.

PMID:
26295830
9.

Novel oxazolidinone calcitonin gene-related peptide (CGRP) receptor antagonists for the acute treatment of migraine.

Crowley BM, Stump CA, Nguyen DN, Potteiger CM, McWherter MA, Paone DV, Quigley AG, Bruno JG, Cui D, Culberson JC, Danziger A, Fandozzi C, Gauvreau D, Kemmerer AL, Menzel K, Moore EL, Mosser SD, Reddy V, White RB, Salvatore CA, Kane SA, Bell IM, Selnick HG, Fraley ME, Burgey CS.

Bioorg Med Chem Lett. 2015 Nov 1;25(21):4777-4781. doi: 10.1016/j.bmcl.2015.07.021. Epub 2015 Jul 14.

PMID:
26231160
10.

Regulation of Human PAX6 Expression by miR-7.

Needhamsen M, White RB, Giles KM, Dunlop SA, Thomas MG.

Evol Bioinform Online. 2014 Jul 14;10:107-13. doi: 10.4137/EBO.S13739. eCollection 2014.

11.

[(11)C]MK-4232: The First Positron Emission Tomography Tracer for the Calcitonin Gene-Related Peptide Receptor.

Bell IM, Gallicchio SN, Stump CA, Bruno JG, Fan H, Gantert LT, Hostetler ED, Kemmerer AL, McWherter M, Moore EL, Mosser SD, Purcell ML, Riffel K, Salvatore CA, Sanabria-Bohórquez S, Staas DD, White RB, Williams M, Zartman CB, Cook JJ, Hargreaves RJ, Kane SA, Graham SL, Selnick HG.

ACS Med Chem Lett. 2013 Jul 18;4(9):863-8. doi: 10.1021/ml400199p. eCollection 2013 Sep 12.

12.

Benzimidazole CB2 agonists: design, synthesis and SAR.

Nanda KK, Henze DA, Della Penna K, Desai R, Leitl M, Lemaire W, White RB, Yeh S, Brouillette JN, Hartman GD, Bilodeau MT, Trotter BW.

Bioorg Med Chem Lett. 2014 Feb 15;24(4):1218-21. doi: 10.1016/j.bmcl.2013.12.068. Epub 2013 Dec 25.

PMID:
24461289
13.

Sphingosine-1-phosphate receptor 3 influences cell cycle progression in muscle satellite cells.

Fortier M, Figeac N, White RB, Knopp P, Zammit PS.

Dev Biol. 2013 Oct 15;382(2):504-16. doi: 10.1016/j.ydbio.2013.07.006. Epub 2013 Aug 2.

14.

The Hippo pathway member Yap plays a key role in influencing fate decisions in muscle satellite cells.

Judson RN, Tremblay AM, Knopp P, White RB, Urcia R, De Bari C, Zammit PS, Camargo FD, Wackerhage H.

J Cell Sci. 2012 Dec 15;125(Pt 24):6009-19. doi: 10.1242/jcs.109546. Epub 2012 Oct 4.

15.

MK-8825: a potent and selective CGRP receptor antagonist with good oral activity in rats.

Bell IM, Stump CA, Gallicchio SN, Staas DD, Zartman CB, Moore EL, Sain N, Urban M, Bruno JG, Calamari A, Kemmerer AL, Mosser SD, Fandozzi C, White RB, Zrada MM, Selnick HG, Graham SL, Vacca JP, Kane SA, Salvatore CA.

Bioorg Med Chem Lett. 2012 Jun 15;22(12):3941-5. doi: 10.1016/j.bmcl.2012.04.105. Epub 2012 Apr 30.

PMID:
22607672
16.

Moving beyond tyrosine hydroxylase to define dopaminergic neurons for use in cell replacement therapies for Parkinson's disease.

White RB, Thomas MG.

CNS Neurol Disord Drug Targets. 2012 Jun 1;11(4):340-9. Review.

PMID:
22483315
17.

Imidazopyridine CB2 agonists: optimization of CB2/CB1 selectivity and implications for in vivo analgesic efficacy.

Trotter BW, Nanda KK, Burgey CS, Potteiger CM, Deng JZ, Green AI, Hartnett JC, Kett NR, Wu Z, Henze DA, Della Penna K, Desai R, Leitl MD, Lemaire W, White RB, Yeh S, Urban MO, Kane SA, Hartman GD, Bilodeau MT.

Bioorg Med Chem Lett. 2011 Apr 15;21(8):2354-8. doi: 10.1016/j.bmcl.2011.02.082. Epub 2011 Mar 1.

PMID:
21420860
18.

Decahydroquinoline amides as highly selective CB2 agonists: role of selectivity on in vivo efficacy in a rodent model of analgesia.

Manley PJ, Zartman A, Paone DV, Burgey CS, Henze DA, Della Penna K, Desai R, Leitl MD, Lemaire W, White RB, Yeh S, Urban MO, Kane SA, Hartman GD, Bilodeau MT, Trotter BW.

Bioorg Med Chem Lett. 2011 Apr 15;21(8):2359-64. doi: 10.1016/j.bmcl.2011.02.078. Epub 2011 Feb 26.

PMID:
21420857
19.

Uncoordinated transcription and compromised muscle function in the lmna-null mouse model of Emery- Emery-Dreyfuss muscular dystrophy.

Gnocchi VF, Scharner J, Huang Z, Brady K, Lee JS, White RB, Morgan JE, Sun YB, Ellis JA, Zammit PS.

PLoS One. 2011 Feb 22;6(2):e16651. doi: 10.1371/journal.pone.0016651.

20.

P3 optimization of functional potency, in vivo efficacy and oral bioavailability in 3-aminopyrazinone thrombin inhibitors bearing non-charged groups at the P1 position.

Isaacs RC, Newton CL, Cutrona KJ, Mercer SP, Dorsey BD, McDonough CM, Cook JJ, Krueger JA, Lewis SD, Lucas BJ, Lyle EA, Lynch JJ, Miller-Stein C, Michener MT, Wallace AA, White RB, Wong BK.

Bioorg Med Chem Lett. 2011 Mar 1;21(5):1532-5. doi: 10.1016/j.bmcl.2010.12.108. Epub 2010 Dec 28.

PMID:
21295466
21.

Looks like a duck, quacks like a duck … still behaves like a bone marrow stromal cell.

White RB.

Transl Res. 2011 Feb;157(2):53-5. doi: 10.1016/j.trsl.2010.12.001. Epub 2010 Dec 15. No abstract available.

PMID:
21256456
22.

Neoclassical transport in the helical reversed-field pinch.

Gobbin M, Spizzo G, Marrelli L, White RB.

Phys Rev Lett. 2010 Nov 5;105(19):195006. Epub 2010 Nov 4.

PMID:
21231177
23.

Discovery of triarylethanolamine inhibitors of the Kv1.5 potassium channel.

Beshore DC, Liverton NJ, McIntyre CJ, Claiborne CF, Libby B, Culberson JC, Salata JJ, Regan CP, Lynch JJ, Kiss L, Spencer RH, Kane SA, White RB, Yeh S, Hartman GD, Dinsmore CJ.

Bioorg Med Chem Lett. 2010 Apr 15;20(8):2493-6. doi: 10.1016/j.bmcl.2010.03.005. Epub 2010 Mar 4.

PMID:
20304642
24.

Dynamics of muscle fibre growth during postnatal mouse development.

White RB, Biérinx AS, Gnocchi VF, Zammit PS.

BMC Dev Biol. 2010 Feb 22;10:21. doi: 10.1186/1471-213X-10-21.

25.

Pharmacological properties of MK-3207, a potent and orally active calcitonin gene-related peptide receptor antagonist.

Salvatore CA, Moore EL, Calamari A, Cook JJ, Michener MS, O'Malley S, Miller PJ, Sur C, Williams DL Jr, Zeng Z, Danziger A, Lynch JJ, Regan CP, Fay JF, Tang YS, Li CC, Pudvah NT, White RB, Bell IM, Gallicchio SN, Graham SL, Selnick HG, Vacca JP, Kane SA.

J Pharmacol Exp Ther. 2010 Apr;333(1):152-60. doi: 10.1124/jpet.109.163816. Epub 2010 Jan 11.

PMID:
20065019
26.

Further characterisation of the molecular signature of quiescent and activated mouse muscle satellite cells.

Gnocchi VF, White RB, Ono Y, Ellis JA, Zammit PS.

PLoS One. 2009;4(4):e5205. doi: 10.1371/journal.pone.0005205. Epub 2009 Apr 16.

27.

Integrated functions of Pax3 and Pax7 in the regulation of proliferation, cell size and myogenic differentiation.

Collins CA, Gnocchi VF, White RB, Boldrin L, Perez-Ruiz A, Relaix F, Morgan JE, Zammit PS.

PLoS One. 2009;4(2):e4475. doi: 10.1371/journal.pone.0004475. Epub 2009 Feb 16.

28.

Anomalous flattening of the fast-ion profile during Alfvén-Eigenmode activity.

Heidbrink WW, Gorelenkov NN, Luo Y, Van Zeeland MA, White RB, Austin ME, Burrell KH, Kramer GJ, Makowski MA, McKee GR, Nazikian R; DIII-D team.

Phys Rev Lett. 2007 Dec 14;99(24):245002. Epub 2007 Dec 12.

29.

Genome-wide discovery of Pax7 target genes during development.

White RB, Ziman MR.

Physiol Genomics. 2008 Mar 14;33(1):41-9. doi: 10.1152/physiolgenomics.00256.2007. Epub 2008 Jan 15.

PMID:
18198279
30.

Androgen receptors in a cichlid fish, Astatotilapia burtoni: structure, localization, and expression levels.

Harbott LK, Burmeister SS, White RB, Vagell M, Fernald RD.

J Comp Neurol. 2007 Sep 1;504(1):57-73.

31.

Improved particle confinement in transition from multiple-helicity to quasi-single-helicity regimes of a reversed-field pinch.

Frassinetti L, Predebon I, Koguchi H, Yagi Y, Hirano Y, Sakakita H, Spizzo G, White RB.

Phys Rev Lett. 2006 Oct 27;97(17):175001. Epub 2006 Oct 24.

PMID:
17155477
32.

Design and synthesis of novel isoquinoline-3-nitriles as orally bioavailable Kv1.5 antagonists for the treatment of atrial fibrillation.

Trotter BW, Nanda KK, Kett NR, Regan CP, Lynch JJ, Stump GL, Kiss L, Wang J, Spencer RH, Kane SA, White RB, Zhang R, Anderson KD, Liverton NJ, McIntyre CJ, Beshore DC, Hartman GD, Dinsmore CJ.

J Med Chem. 2006 Nov 30;49(24):6954-7.

PMID:
17125248
33.

Discovery of potent, selective 4-fluoroproline-based thrombin inhibitors with improved metabolic stability.

Staas DD, Savage KL, Sherman VL, Shimp HL, Lyle TA, Tran LO, Wiscount CM, McMasters DR, Sanderson PE, Williams PD, Lucas BJ Jr, Krueger JA, Lewis SD, White RB, Yu S, Wong BK, Kochansky CJ, Anari MR, Yan Y, Vacca JP.

Bioorg Med Chem. 2006 Oct 15;14(20):6900-16. Epub 2006 Jul 25.

PMID:
16870455
34.

A comparative analysis of shotgun-cloning and tagged-random amplification-cloning of chromatin immunoprecipitation-isolated genome fragments.

White RB, Ziman MR.

Biochem Biophys Res Commun. 2006 Jul 28;346(2):479-83. Epub 2006 Jun 2.

PMID:
16762317
35.

Transport barrier inside the reversal surface in the chaotic regime of the reversed-field pinch.

Spizzo G, Cappello S, Cravotta A, Escande DF, Predebon I, Marrelli L, Martin P, White RB.

Phys Rev Lett. 2006 Jan 20;96(2):025001. Epub 2006 Jan 17.

PMID:
16486588
36.

P2 pyridine N-oxide thrombin inhibitors: a novel peptidomimetic scaffold.

Nantermet PG, Burgey CS, Robinson KA, Pellicore JM, Newton CL, Deng JZ, Selnick HG, Lewis SD, Lucas BJ, Krueger JA, Miller-Stein C, White RB, Wong B, McMasters DR, Wallace AA, Lynch JJ Jr, Yan Y, Chen Z, Kuo L, Gardell SJ, Shafer JA, Vacca JP, Lyle TA.

Bioorg Med Chem Lett. 2005 Jun 2;15(11):2771-5.

PMID:
15911253
37.

9-hydroxyazafluorenes and their use in thrombin inhibitors.

Stauffer KJ, Williams PD, Selnick HG, Nantermet PG, Newton CL, Homnick CF, Zrada MM, Lewis SD, Lucas BJ, Krueger JA, Pietrak BL, Lyle EA, Singh R, Miller-Stein C, White RB, Wong B, Wallace AA, Sitko GR, Cook JJ, Holahan MA, Stranieri-Michener M, Leonard YM, Lynch JJ Jr, McMasters DR, Yan Y.

J Med Chem. 2005 Apr 7;48(7):2282-93.

PMID:
15801822
38.

Isolation and expression analysis of a Pax group III gene from the crustacean Cherax destructor.

White RB, Lamey TM, Ziman M, Koenders A.

Dev Genes Evol. 2005 Jun;215(6):306-12. Epub 2005 Mar 17.

PMID:
15772827
39.

Particle-transport analysis in reversed field pinch helical states.

Predebon I, Marrelli L, White RB, Martin P.

Phys Rev Lett. 2004 Oct 1;93(14):145001. Epub 2004 Sep 27.

PMID:
15524802
40.

Adherence to the dialysis prescription: partnering with patients for improved outcomes.

White RB.

Nephrol Nurs J. 2004 Jul-Aug;31(4):432-5. Review.

PMID:
15453235
41.

Low molecular weight thrombin inhibitors with excellent potency, metabolic stability, and oral bioavailability.

Morrissette MM, Stauffer KJ, Williams PD, Lyle TA, Vacca JP, Krueger JA, Lewis SD, Lucas BJ, Wong BK, White RB, Miller-Stein C, Lyle EA, Wallace AA, Leonard YM, Welsh DC, Lynch JJ, McMasters DR.

Bioorg Med Chem Lett. 2004 Aug 16;14(16):4161-4.

PMID:
15261262
42.

Discovery and evaluation of potent P1 aryl heterocycle-based thrombin inhibitors.

Young MB, Barrow JC, Glass KL, Lundell GF, Newton CL, Pellicore JM, Rittle KE, Selnick HG, Stauffer KJ, Vacca JP, Williams PD, Bohn D, Clayton FC, Cook JJ, Krueger JA, Kuo LC, Lewis SD, Lucas BJ, McMasters DR, Miller-Stein C, Pietrak BL, Wallace AA, White RB, Wong B, Yan Y, Nantermet PG.

J Med Chem. 2004 Jun 3;47(12):2995-3008.

PMID:
15163182
43.

Observations of multiple magnetic islands in the core of a reversed field pinch.

Franz P, Marrelli L, Piovesan P, Chapman BE, Martin P, Predebon I, Spizzo G, White RB, Xiao C.

Phys Rev Lett. 2004 Mar 26;92(12):125001. Epub 2004 Mar 25.

PMID:
15089679
44.

Zonal-flow dynamics and size scaling of anomalous transport.

Chen L, White RB, Zonca F.

Phys Rev Lett. 2004 Feb 20;92(7):075004. Epub 2004 Feb 20.

PMID:
14995865
45.

Chronic neuropeptide Y infusion into the lateral ventricle induces sustained feeding and obesity in mice lacking either Npy1r or Npy5r expression.

Raposinho PD, Pedrazzini T, White RB, Palmiter RD, Aubert ML.

Endocrinology. 2004 Jan;145(1):304-10. Epub 2003 Oct 2.

PMID:
14525913
46.

Multiple corticosteroid receptors in a teleost fish: distinct sequences, expression patterns, and transcriptional activities.

Greenwood AK, Butler PC, White RB, DeMarco U, Pearce D, Fernald RD.

Endocrinology. 2003 Oct;144(10):4226-36. Epub 2003 Jul 3.

PMID:
12959971
47.

Near threshold anomalous transport in the standard map.

White RB, Benkadda S, Kassibrakis S, Zaslavsky GM.

Chaos. 1998 Dec;8(4):757-767.

PMID:
12779781
48.

Pharmacokinetic optimization of 3-amino-6-chloropyrazinone acetamide thrombin inhibitors. Implementation of P3 pyridine N-oxides to deliver an orally bioavailable series containing P1 N-benzylamides.

Burgey CS, Robinson KA, Lyle TA, Nantermet PG, Selnick HG, Isaacs RC, Lewis SD, Lucas BJ, Krueger JA, Singh R, Miller-Stein C, White RB, Wong B, Lyle EA, Stranieri MT, Cook JJ, McMasters DR, Pellicore JM, Pal S, Wallace AA, Clayton FC, Bohn D, Welsh DC, Lynch JJ Jr, Yan Y, Chen Z, Kuo L, Gardell SJ, Shafer JA, Vacca JP.

Bioorg Med Chem Lett. 2003 Apr 7;13(7):1353-7.

PMID:
12657281
49.

Metabolism-directed optimization of 3-aminopyrazinone acetamide thrombin inhibitors. Development of an orally bioavailable series containing P1 and P3 pyridines.

Burgey CS, Robinson KA, Lyle TA, Sanderson PE, Lewis SD, Lucas BJ, Krueger JA, Singh R, Miller-Stein C, White RB, Wong B, Lyle EA, Williams PD, Coburn CA, Dorsey BD, Barrow JC, Stranieri MT, Holahan MA, Sitko GR, Cook JJ, McMasters DR, McDonough CM, Sanders WM, Wallace AA, Clayton FC, Bohn D, Leonard YM, Detwiler TJ Jr, Lynch JJ Jr, Yan Y, Chen Z, Kuo L, Gardell SJ, Shafer JA, Vacca JP.

J Med Chem. 2003 Feb 13;46(4):461-73.

PMID:
12570369

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