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Quantitative Interpretation of Genetic Toxicity Dose-Response Data for Risk Assessment and Regulatory Decision-making: Current Status and Emerging Priorities.

White PA, Long AS, Johnson GE.

Environ Mol Mutagen. 2019 Dec 3. doi: 10.1002/em.22351. [Epub ahead of print]


Utility of a next generation framework for assessment of genomic damage: A case study using the industrial chemical benzene.

Luijten M, Ball NS, Dearfield KL, Gollapudi BB, Johnson GE, Madia F, Peel L, Pfuhler S, Settivari RS, Ter Burg W, White PA, van Benthem J.

Environ Mol Mutagen. 2019 Nov 9. doi: 10.1002/em.22346. [Epub ahead of print]


The IWGT in vitro Mammalian Cell Gene Mutation (MCGM) assays working group-Introductory remarks & consensus statements.

Gollapudi BB, White PA, Honma M.

Mutat Res. 2019 Dec;848:403061. doi: 10.1016/j.mrgentox.2019.05.017. Epub 2019 May 31.


In vitro mammalian cell mutation assays based on transgenic reporters: A report of the International Workshop on Genotoxicity Testing (IWGT).

White PA, Luijten M, Mishima M, Cox JA, Hanna JN, Maertens RM, Zwart EP.

Mutat Res. 2019 Nov;847:403039. doi: 10.1016/j.mrgentox.2019.04.002. Epub 2019 Apr 13.


Body, head, and gaze orientation in portraits: Effects of artistic medium, date of execution, and gender.

White PA.

Laterality. 2019 Nov 3:1-33. doi: 10.1080/1357650X.2019.1684935. [Epub ahead of print]


Mutation as a Toxicological Endpoint for Regulatory Decision-Making.

Heflich RH, Johnson GE, Zeller A, Marchetti F, Douglas GR, Witt KL, Gollapudi BB, White PA.

Environ Mol Mutagen. 2019 Oct 10. doi: 10.1002/em.22338. [Epub ahead of print]


ICTV Virus Taxonomy Profile: Caliciviridae.

Vinjé J, Estes MK, Esteves P, Green KY, Katayama K, Knowles NJ, L'Homme Y, Martella V, Vennema H, White PA, Ictv Report Consortium.

J Gen Virol. 2019 Nov;100(11):1469-1470. doi: 10.1099/jgv.0.001332.


Polycyclic aromatic hydrocarbon (PAH) and metal contamination of air and surfaces exposed to combustion emissions during emergency fire suppression: Implications for firefighters' exposures.

Keir JLA, Akhtar US, Matschke DMJ, White PA, Kirkham TL, Chan HM, Blais JM.

Sci Total Environ. 2020 Jan 1;698:134211. doi: 10.1016/j.scitotenv.2019.134211. Epub 2019 Aug 31.


The IARC Monographs: Updated procedures for modern and transparent evidence synthesis in cancer hazard identification.

Samet JM, Chiu WA, Cogliano V, Jinot J, Kriebel D, Lunn RM, Beland FA, Bero L, Browne P, Fritschi L, Kanno J, Lachenmeier DW, Lan Q, Lasfargues G, Curieux FL, Peters S, Shubat P, Sone H, White MC, Williamson J, Yakubovskaya M, Siemiatycki J, White PA, Guyton KZ, Schubauer-Berigan MK, Hall AL, Grosse Y, Bouvard V, Benbrahim-Tallaa L, Ghissassi FE, Lauby-Secretan B, Armstrong B, Saracci R, Zavadil J, Straif K, Wild CP.

J Natl Cancer Inst. 2019 Sep 9. pii: djz169. doi: 10.1093/jnci/djz169. [Epub ahead of print]


Updated classification of norovirus genogroups and genotypes.

Chhabra P, de Graaf M, Parra GI, Chan MC, Green K, Martella V, Wang Q, White PA, Katayama K, Vennema H, Koopmans MPG, Vinjé J.

J Gen Virol. 2019 Oct;100(10):1393-1406. doi: 10.1099/jgv.0.001318.


Integrated in silico and in vitro genotoxicity assessment of thirteen data-poor substances.

Tran YK, Buick JK, Keir JLA, Williams A, Swartz CD, Recio L, White PA, Lambert IB, Yauk CL.

Regul Toxicol Pharmacol. 2019 Oct;107:104427. doi: 10.1016/j.yrtph.2019.104427. Epub 2019 Jul 20.


The mutagenic activity of select azo compounds in MutaMouse target tissues in vivo and primary hepatocytes in vitro.

Cox JA, White PA.

Mutat Res. 2019 Aug;844:25-34. doi: 10.1016/j.mrgentox.2019.06.003. Epub 2019 Jun 13.


Novel insights into endogenous RNA viral elements in Ixodes scapularis and other arbovirus vector genomes.

Russo AG, Kelly AG, Enosi Tuipulotu D, Tanaka MM, White PA.

Virus Evol. 2019 Jun 18;5(1):vez010. doi: 10.1093/ve/vez010. eCollection 2019 Jan.


Mouse Norovirus Infection Arrests Host Cell Translation Uncoupled from the Stress Granule-PKR-eIF2α Axis.

Fritzlar S, Aktepe TE, Chao YW, Kenney ND, McAllaster MR, Wilen CB, White PA, Mackenzie JM.

MBio. 2019 Jun 18;10(3). pii: e00960-19. doi: 10.1128/mBio.00960-19.


The Adenosine Analogue NITD008 has Potent Antiviral Activity against Human and Animal Caliciviruses.

Enosi Tuipulotu D, Fumian TM, Netzler NE, Mackenzie JM, White PA.

Viruses. 2019 May 30;11(6). pii: E496. doi: 10.3390/v11060496.


Genetic analysis of African lions (Panthera leo) in Zambia support movement across anthropogenic and geographical barriers.

Curry CJ, White PA, Derr JN.

PLoS One. 2019 May 31;14(5):e0217179. doi: 10.1371/journal.pone.0217179. eCollection 2019.


Glucagon-Like Peptide-1-Mediated Cardioprotection Does Not Reduce Right Ventricular Stunning and Cumulative Ischemic Dysfunction After Coronary Balloon Occlusion.

Giblett JP, Axell RG, White PA, Aetesam-Ur-Rahman M, Clarke SJ, Figg N, Bennett MR, West NEJ, Hoole SP.

JACC Basic Transl Sci. 2019 Apr 29;4(2):222-233. doi: 10.1016/j.jacbts.2018.12.002. eCollection 2019 Apr.


Genetic diversity and quantification of human mastadenoviruses in wastewater from Sydney and Melbourne, Australia.

Lun JH, Crosbie ND, White PA.

Sci Total Environ. 2019 Jul 20;675:305-312. doi: 10.1016/j.scitotenv.2019.04.162. Epub 2019 Apr 11.


Antiviral Candidates for Treating Hepatitis E Virus Infection.

Netzler NE, Enosi Tuipulotu D, Vasudevan SG, Mackenzie JM, White PA.

Antimicrob Agents Chemother. 2019 May 24;63(6). pii: e00003-19. doi: 10.1128/AAC.00003-19. Print 2019 Jun.


The Microtubule-Associated Innate Immune Sensor GEF-H1 Does Not Influence Mouse Norovirus Replication in Murine Macrophages.

Fritzlar S, White PA, Mackenzie JM.

Viruses. 2019 Jan 10;11(1). pii: E47. doi: 10.3390/v11010047.


Norovirus antivirals: Where are we now?

Netzler NE, Enosi Tuipulotu D, White PA.

Med Res Rev. 2019 May;39(3):860-886. doi: 10.1002/med.21545. Epub 2018 Dec 25. Review.


Detection of norovirus epidemic genotypes in raw sewage using next generation sequencing.

Fumian TM, Fioretti JM, Lun JH, Dos Santos IAL, White PA, Miagostovich MP.

Environ Int. 2019 Feb;123:282-291. doi: 10.1016/j.envint.2018.11.054. Epub 2018 Dec 12.


Re: Gi et al. 2018, In vivo positive mutagenicity of 1,4-dioxane and quantitative analysis of its mutagenicity and carcinogenicity in rats, Archives of Toxicology 92:3207-3221.

White PA, Zeller A, Pfuhler S, Johnson GE.

Arch Toxicol. 2019 Jan;93(1):211-212. doi: 10.1007/s00204-018-2370-1. Epub 2018 Dec 11. No abstract available. Erratum in: Arch Toxicol. 2019 Jun;93(6):1777.


Differences over time in head orientation in European portrait paintings.

White PA.

Laterality. 2019 Sep;24(5):525-537. doi: 10.1080/1357650X.2018.1545780. Epub 2018 Nov 16.


Recombinant GII.P16/GII.4 Sydney 2012 Was the Dominant Norovirus Identified in Australia and New Zealand in 2017.

Lun JH, Hewitt J, Yan GJH, Enosi Tuipulotu D, Rawlinson WD, White PA.

Viruses. 2018 Oct 9;10(10). pii: E548. doi: 10.3390/v10100548.


Potential Therapeutic Agents for Feline Calicivirus Infection.

Fumian TM, Tuipulotu DE, Netzler NE, Lun JH, Russo AG, Yan GJH, White PA.

Viruses. 2018 Aug 16;10(8). pii: E433. doi: 10.3390/v10080433.


Draft genome assembly of the invasive cane toad, Rhinella marina.

Edwards RJ, Tuipulotu DE, Amos TG, O'Meally D, Richardson MF, Russell TL, Vallinoto M, Carneiro M, Ferrand N, Wilkins MR, Sequeira F, Rollins LA, Holmes EC, Shine R, White PA.

Gigascience. 2018 Sep 1;7(9). doi: 10.1093/gigascience/giy095.


Mouse Norovirus Infection Reduces the Surface Expression of Major Histocompatibility Complex Class I Proteins and Inhibits CD8+ T Cell Recognition and Activation.

Fritzlar S, Jegaskanda S, Aktepe TE, Prier JE, Holz LE, White PA, Mackenzie JM.

J Virol. 2018 Aug 29;92(18). pii: e00286-18. doi: 10.1128/JVI.00286-18. Print 2018 Sep 15.


Viral Discovery in the Invasive Australian Cane Toad (Rhinella marina) Using Metatranscriptomic and Genomic Approaches.

Russo AG, Eden JS, Enosi Tuipulotu D, Shi M, Selechnik D, Shine R, Rollins LA, Holmes EC, White PA.

J Virol. 2018 Aug 16;92(17). pii: e00768-18. doi: 10.1128/JVI.00768-18. Print 2018 Sep 1.


Gastroenteritis outbreak at a health function caused by an emerging recombinant strain of Norovirus GII.P16/GII.4 Sydney 2012, Australia.

Jones BJ, Flint J, Collins J, White PA, Lun JH, Durrheim DN.

Epidemiol Infect. 2018 Jun;146(8):970-971. doi: 10.1017/S0950268818000869. Epub 2018 Apr 16.


Emerging recombinant noroviruses identified by clinical and waste water screening.

Lun JH, Hewitt J, Sitabkhan A, Eden JS, Enosi Tuipulotu D, Netzler NE, Morrell L, Merif J, Jones R, Huang B, Warrilow D, Ressler KA, Ferson MJ, Dwyer DE, Kok J, Rawlinson WD, Deere D, Crosbie ND, White PA.

Emerg Microbes Infect. 2018 Mar 29;7(1):50. doi: 10.1038/s41426-018-0047-8.


Nucleocytoplasmic shuttling of the West Nile virus RNA-dependent RNA polymerase NS5 is critical to infection.

Lopez-Denman AJ, Russo A, Wagstaff KM, White PA, Jans DA, Mackenzie JM.

Cell Microbiol. 2018 Aug;20(8):e12848. doi: 10.1111/cmi.12848. Epub 2018 Apr 24.


Is conscious perception a series of discrete temporal frames?

White PA.

Conscious Cogn. 2018 Apr;60:98-126. doi: 10.1016/j.concog.2018.02.012. Epub 2018 Mar 14. Review.


TLR7 Agonists Display Potent Antiviral Effects against Norovirus Infection via Innate Stimulation.

Enosi Tuipulotu D, Netzler NE, Lun JH, Mackenzie JM, White PA.

Antimicrob Agents Chemother. 2018 Apr 26;62(5). pii: e02417-17. doi: 10.1128/AAC.02417-17. Print 2018 May.


In silico screening for human norovirus antivirals reveals a novel non-nucleoside inhibitor of the viral polymerase.

Ferla S, Netzler NE, Ferla S, Veronese S, Tuipulotu DE, Guccione S, Brancale A, White PA, Bassetto M.

Sci Rep. 2018 Mar 7;8(1):4129. doi: 10.1038/s41598-018-22303-y.


Benchmark dose analyses of multiple genetic toxicity endpoints permit robust, cross-tissue comparisons of MutaMouse responses to orally delivered benzo[a]pyrene.

Long AS, Wills JW, Krolak D, Guo M, Dertinger SD, Arlt VM, White PA.

Arch Toxicol. 2018 Feb;92(2):967-982. doi: 10.1007/s00204-017-2099-2. Epub 2017 Nov 24.


Membrane alterations induced by nonstructural proteins of human norovirus.

Doerflinger SY, Cortese M, Romero-Brey I, Menne Z, Tubiana T, Schenk C, White PA, Bartenschlager R, Bressanelli S, Hansman GS, Lohmann V.

PLoS Pathog. 2017 Oct 27;13(10):e1006705. doi: 10.1371/journal.ppat.1006705. eCollection 2017 Oct.


Characterizing Nanoparticles in Biological Matrices: Tipping Points in Agglomeration State and Cellular Delivery In Vitro.

Wills JW, Summers HD, Hondow N, Sooresh A, Meissner KE, White PA, Rees P, Brown A, Doak SH.

ACS Nano. 2017 Dec 26;11(12):11986-12000. doi: 10.1021/acsnano.7b03708. Epub 2017 Nov 1.


Correction: Age Estimation of African Lions Panthera leo by Ratio of Tooth Areas.

White PA, Ikanda D, Ferrante L, Chardonnet P, Mesochina P, Cameriere R.

PLoS One. 2017 Oct 19;12(10):e0187003. doi: 10.1371/journal.pone.0187003. eCollection 2017.


Elevated Exposures to Polycyclic Aromatic Hydrocarbons and Other Organic Mutagens in Ottawa Firefighters Participating in Emergency, On-Shift Fire Suppression.

Keir JLA, Akhtar US, Matschke DMJ, Kirkham TL, Chan HM, Ayotte P, White PA, Blais JM.

Environ Sci Technol. 2017 Nov 7;51(21):12745-12755. doi: 10.1021/acs.est.7b02850. Epub 2017 Oct 18.


Comparing BMD-derived genotoxic potency estimations across variants of the transgenic rodent gene mutation assay.

Wills JW, Johnson GE, Battaion HL, Slob W, White PA.

Environ Mol Mutagen. 2017 Dec;58(9):632-643. doi: 10.1002/em.22137. Epub 2017 Sep 25.


RNA Sequencing of Murine Norovirus-Infected Cells Reveals Transcriptional Alteration of Genes Important to Viral Recognition and Antigen Presentation.

Enosi Tuipulotu D, Netzler NE, Lun JH, Mackenzie JM, White PA.

Front Immunol. 2017 Aug 11;8:959. doi: 10.3389/fimmu.2017.00959. eCollection 2017.


Performance of the in vitro transgene mutation assay in MutaMouse FE1 cells: Evaluation of nine misleading ("False") positive chemicals.

Maertens RM, Long AS, White PA.

Environ Mol Mutagen. 2017 Oct;58(8):582-591. doi: 10.1002/em.22125. Epub 2017 Aug 26.


Persistent infections in immunocompromised hosts are rarely sources of new pathogen variants.

Eden JS, Chisholm RH, Bull RA, White PA, Holmes EC, Tanaka MM.

Virus Evol. 2017 Jul 28;3(2):vex018. doi: 10.1093/ve/vex018. eCollection 2017 Jul.


Broad-spectrum non-nucleoside inhibitors for caliciviruses.

Netzler NE, Enosi Tuipulotu D, Eltahla AA, Lun JH, Ferla S, Brancale A, Urakova N, Frese M, Strive T, Mackenzie JM, White PA.

Antiviral Res. 2017 Oct;146:65-75. doi: 10.1016/j.antiviral.2017.07.014. Epub 2017 Jul 27.


Global Spread of Norovirus GII.17 Kawasaki 308, 2014-2016.

Chan MCW, Hu Y, Chen H, Podkolzin AT, Zaytseva EV, Komano J, Sakon N, Poovorawan Y, Vongpunsawad S, Thanusuwannasak T, Hewitt J, Croucher D, Collins N, Vinjé J, Pang XL, Lee BE, de Graaf M, van Beek J, Vennema H, Koopmans MPG, Niendorf S, Poljsak-Prijatelj M, Steyer A, White PA, Lun JH, Mans J, Hung TN, Kwok K, Cheung K, Lee N, Chan PKS.

Emerg Infect Dis. 2017 Aug;23(8):1359-1354. doi: 10.3201/eid2308.161138.

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