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Setting Our Sights on Infectious Diseases.

De Rycker M, Horn D, Aldridge B, Amewu RK, Barry CE 3rd, Buckner FS, Cook S, Ferguson MAJ, Gobeau N, Herrmann J, Herrling P, Hope W, Keiser J, Lafuente-Monasterio MJ, Leeson PD, Leroy D, Manjunatha UH, McCarthy J, Miles TJ, Mizrahi V, Moshynets O, Niles J, Overington JP, Pottage J, Rao SPS, Read KD, Ribeiro I, Silver LL, Southern J, Spangenberg T, Sundar S, Taylor C, Van Voorhis W, White NJ, Wyllie S, Wyatt PG, Gilbert IH.

ACS Infect Dis. 2019 Dec 6. doi: 10.1021/acsinfecdis.9b00371. [Epub ahead of print]


Associations Between Microstructure, Amyloid, and Cognition in Amnestic Mild Cognitive Impairment and Dementia.

Reas ET, Hagler DJ, Kuperman JM, Wierenga CE, Galasko D, White NS, Dale AM, Banks SJ, McEvoy LK, Brewer JB.

J Alzheimers Dis. 2019 Nov 23. doi: 10.3233/JAD-190871. [Epub ahead of print]


Antibiotic Impregnated Cement Dowel in a Tibial Stump to Salvage Infected Below-Knee Amputation in a Diabetic.

Sidhu SP, White NJ.

J Am Acad Orthop Surg Glob Res Rev. 2019 Oct 15;3(10). pii: e18.00042. doi: 10.5435/JAAOSGlobal-D-18-00042. eCollection 2019 Oct.


Palliative care training in undergraduate medical, nursing and allied health: a survey.

White N, Oostendorp LJ, Minton O, Yardley S, Stone P.

BMJ Support Palliat Care. 2019 Nov 20. pii: bmjspcare-2019-002025. doi: 10.1136/bmjspcare-2019-002025. [Epub ahead of print]


A Translational Approach to Predicting the Efficacy of Maraviroc-based Regimens as HIV Pre-exposure Prophylaxis.

Srinivas N, Cottrell M, Maffuid K, Prince HA, Nelson JAE, White N, Sykes C, Dellon ES, Madanick RD, Shaheen NJ, Gonzalez D, Kashuba ADM.

Antimicrob Agents Chemother. 2019 Nov 18. pii: AAC.01729-19. doi: 10.1128/AAC.01729-19. [Epub ahead of print]


Phosphoramidates as Steering Elements for Highly Selective Access to Complementary Imidazo[1,2-a]pyrimidine Isomers.

White NA, Clagg K, Sirois LE, Mack KA, Al-Sayah MA, Nack WA, O'Shea PD, Zhang H, Gosselin F.

Org Lett. 2019 Nov 18. doi: 10.1021/acs.orglett.9b03702. [Epub ahead of print]


Online training improves medical students' ability to recognise when a person is dying: The ORaClES randomised controlled trial.

White N, Oostendorp LJ, Tomlinson C, Yardley S, Ricciardi F, Gökalp H, Minton O, Boland JW, Clark B, Harries P, Stone P.

Palliat Med. 2019 Nov 14:269216319880767. doi: 10.1177/0269216319880767. [Epub ahead of print]


Application of ensemble methods to analyse the decline of organochlorine pesticides in relation to the interactions between age, gender and time.

Thomas A, White NM, Leontjew Toms LM, Mengersen K.

PLoS One. 2019 Nov 13;14(11):e0223956. doi: 10.1371/journal.pone.0223956. eCollection 2019.


Author Correction: V2a interneuron differentiation from mouse and human pluripotent stem cells.

Butts JC, Iyer N, White N, Thompson R, Sakiyama-Elbert S, McDevitt TC.

Nat Protoc. 2019 Nov 8. doi: 10.1038/s41596-019-0266-z. [Epub ahead of print]


Safety, pharmacokinetics, and mosquito-lethal effects of ivermectin in combination with dihydroartemisinin-piperaquine and primaquine in healthy adult Thai subjects.

Kobylinski KC, Jittamala P, Hanboonkunupakarn B, Pukrittayakamee S, Pantuwatana K, Phasomkusolsil S, Davidson SA, Winterberg M, Hoglund RM, Mukaka M, van der Pluijm RW, Dondorp A, Day NPJ, White NJ, Tarning J.

Clin Pharmacol Ther. 2019 Nov 7. doi: 10.1002/cpt.1716. [Epub ahead of print]


Cell-Free Hemoglobin Is Associated With Increased Vascular Resistance and Reduced Peripheral Perfusion in Severe Malaria.

Kingston HWF, Ghose A, Rungpradubvong V, Satitthummanid S, Herdman MT, Plewes K, Ishioka H, Leopold SJ, Sinha I, Intharabut B, Piera K, McNeil Y, Mohanty S, Maude RJ, White NJ, Day NPJ, Yeo TW, Hossain MA, Anstey NM, Dondorp AM.

J Infect Dis. 2019 Nov 6. pii: jiz359. doi: 10.1093/infdis/jiz359. [Epub ahead of print]


Reduced cardiac index reserve and hypovolemia in severe falciparum malaria.

Kingston HWF, Ghose A, Rungpradubvong V, Satitthummanid S, Herdman MT, Plewes K, Leopold SJ, Ishioka H, Mohanty S, Maude RJ, Schultz MJ, Lagrand WK, Hossain MA, Day NPJ, White NJ, Anstey NM, Dondorp AM.

J Infect Dis. 2019 Nov 6. pii: jiz568. doi: 10.1093/infdis/jiz568. [Epub ahead of print]


Financial Education and Coaching: A Lifestyle Medicine Approach to Addressing Financial Stress.

White ND, Packard K, Kalkowski J.

Am J Lifestyle Med. 2019 Jul 29;13(6):540-543. doi: 10.1177/1559827619865439. eCollection 2019 Nov-Dec. Review.


Pd-Catalyzed C-N Coupling Reactions Facilitated by Organic Bases: Mechanistic Investigation Leads to Enhanced Reactivity in the Arylation of Weakly Binding Amines.

Dennis JM, White NA, Liu RY, Buchwald SL.

ACS Catal. 2019 May 3;9(5):3822-3830. doi: 10.1021/acscatal.9b00981. Epub 2019 Mar 15.


V2a interneuron differentiation from mouse and human pluripotent stem cells.

Butts JC, Iyer N, White N, Thompson R, Sakiyama-Elbert S, McDevitt TC.

Nat Protoc. 2019 Nov;14(11):3033-3058. doi: 10.1038/s41596-019-0203-1. Epub 2019 Oct 18. Erratum in: Nat Protoc. 2019 Nov 8;:.


Prevalence and Impact of Pharmacy Students as Patient Care Extenders in Medically Underserved Community Pharmacies.

White N, Galt K, Ridgway JE, Skrabal MZ, Jones R, Willman CC.

J Pharm Pract. 2019 Oct 15:897190019881063. doi: 10.1177/0897190019881063. [Epub ahead of print]


Antiretroviral penetration across three preclinical animal models and humans in eight putative HIV viral reservoirs.

Devanathan AS, Pirone JR, Akkina R, Remling-Mulder L, Luciw P, Adamson L, Garcia JV, Kovarova M, White NR, Schauer AP, Blake K, Sykes C, Burgunder EM, Srinivas N, Rosen EP, Kashuba ADM.

Antimicrob Agents Chemother. 2019 Oct 14. pii: AAC.01639-19. doi: 10.1128/AAC.01639-19. [Epub ahead of print]


Recent developments in the management of recurrent Clostridioides difficile infection.

Mendo-Lopez R, Villafuerte-Gálvez J, White N, Mahoney MV, Kelly CP, Alonso CD.

Anaerobe. 2019 Oct 10:102108. doi: 10.1016/j.anaerobe.2019.102108. [Epub ahead of print] Review.


Genome-wide allele-specific methylation is enriched at gene regulatory regions in a multi-generation pedigree from the Norfolk Island isolate.

Benton MC, Lea RA, Macartney-Coxson D, Sutherland HG, White N, Kennedy D, Mengersen K, Haupt LM, Griffiths LR.

Epigenetics Chromatin. 2019 Oct 8;12(1):60. doi: 10.1186/s13072-019-0304-7.


The efficacy of dihydroartemisinin-piperaquine and artemether-lumefantrine with and without primaquine on Plasmodium vivax recurrence: A systematic review and individual patient data meta-analysis.

Commons RJ, Simpson JA, Thriemer K, Abreha T, Adam I, Anstey NM, Assefa A, Awab GR, Baird JK, Barber BE, Chu CS, Dahal P, Daher A, Davis TME, Dondorp AM, Grigg MJ, Humphreys GS, Hwang J, Karunajeewa H, Laman M, Lidia K, Moore BR, Mueller I, Nosten F, Pasaribu AP, Pereira DB, Phyo AP, Poespoprodjo JR, Sibley CH, Stepniewska K, Sutanto I, Thwaites G, Hien TT, White NJ, William T, Woodrow CJ, Guerin PJ, Price RN.

PLoS Med. 2019 Oct 4;16(10):e1002928. doi: 10.1371/journal.pmed.1002928. eCollection 2019 Oct.


Laxative use does not preclude diagnosis or reduce disease severity in Clostridiodes difficile infection.

White NC, Mendo-Lopez R, Papamichael K, Cuddemi CA, Barrett C, Daugherty K, Pollock N, Kelly CP, Alonso CD.

Clin Infect Dis. 2019 Oct 4. pii: ciz978. doi: 10.1093/cid/ciz978. [Epub ahead of print]


The effect of melatonin on ultrasound markers of follicular development: A double-blind placebo-controlled randomised trial.

Fernando S, Wallace EM, Rombauts L, White N, Hong J, Vollenhoven B, Lolatgis N, Hope N, Wong M, Lawrence M, Lawrence A, Russell C, Leong K, Thomas P, da Silva Costa F.

Aust N Z J Obstet Gynaecol. 2019 Oct 3. doi: 10.1111/ajo.13074. [Epub ahead of print]


The effect of supplementation with Scutellaria baicalensis on hepatic function.

Puri BK, White N, Monro JA.

Med Hypotheses. 2019 Dec;133:109402. doi: 10.1016/j.mehy.2019.109402. Epub 2019 Sep 19.


A three dimensional hydrogen bonded organic framework assembled through antielectrostatic hydrogen bonds.

Cullen DA, Gardiner MG, White NG.

Chem Commun (Camb). 2019 Oct 3;55(80):12020-12023. doi: 10.1039/c9cc06707h.


The Past and Future of Experimental Speciation.

White NJ, Snook RR, Eyres I.

Trends Ecol Evol. 2019 Sep 12. pii: S0169-5347(19)30258-7. doi: 10.1016/j.tree.2019.08.009. [Epub ahead of print] Review.


Extracting phylogenetic signal from phylogenomic data: Higher-level relationships of the nightbirds (Strisores).

White ND, Braun MJ.

Mol Phylogenet Evol. 2019 Dec;141:106611. doi: 10.1016/j.ympev.2019.106611. Epub 2019 Sep 11.


Flexible Mid-IR fiber bundle for thermal imaging of inaccessible areas.

Ventura A, Ben Slimen F, Lousteau J, White N, Masoudi A, Janicek P, Poletti F.

Opt Express. 2019 Jul 22;27(15):20259-20272. doi: 10.1364/OE.27.020259.


Systematic Review of l-glutamine for Prevention of Vaso-occlusive Pain Crisis in Patients with Sickle Cell Disease.

Cieri-Hutcherson NE, Hutcherson TC, Conway-Habes EE, Burns BN, White NA.

Pharmacotherapy. 2019 Nov;39(11):1095-1104. doi: 10.1002/phar.2329. Epub 2019 Oct 9. Review.


Associations between restrictive fluid management and renal function and tissue perfusion in adults with severe falciparum malaria - a prospective observational study.

Ishioka H, Plewes K, Pattnaik R, Kingston HWF, Leopold SJ, Herdman MT, Mahanta K, Mohanty A, Dey C, Alam S, Srinamon K, Mohanty A, Maude RJ, White NJ, Day NPJ, Hossain MA, Faiz MA, Charunwatthana P, Mohanty S, Ghose A, Dondorp AM.

J Infect Dis. 2019 Aug 31. pii: jiz449. doi: 10.1093/infdis/jiz449. [Epub ahead of print]


Heart Rate Variability and Cardiac Autonomic Dysfunction: Prevalence, Risk Factors, and Relationship to Arterial Stiffness in the Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) Study.

Shah AS, El Ghormli L, Vajravelu ME, Bacha F, Farrell RM, Gidding SS, Levitt Katz LE, Tryggestad JB, White NH, Urbina EM.

Diabetes Care. 2019 Nov;42(11):2143-2150. doi: 10.2337/dc19-0993. Epub 2019 Sep 9.


A Temporizing Solution to "Artemisinin Resistance".

Chan XS, White NJ, Hien TT.

N Engl J Med. 2019 Sep 5;381(10):989-990. doi: 10.1056/NEJMc1909337. No abstract available.


Meiotic drive reduces egg-to-adult viability in stalk-eyed flies.

Finnegan SR, White NJ, Koh D, Camus MF, Fowler K, Pomiankowski A.

Proc Biol Sci. 2019 Sep 11;286(1910):20191414. doi: 10.1098/rspb.2019.1414. Epub 2019 Sep 4.


Machine learning in predicting graft failure following kidney transplantation: A systematic review of published predictive models.

Senanayake S, White N, Graves N, Healy H, Baboolal K, Kularatna S.

Int J Med Inform. 2019 Oct;130:103957. doi: 10.1016/j.ijmedinf.2019.103957. Epub 2019 Aug 24.


Investigating causal pathways in severe falciparum malaria: A pooled retrospective analysis of clinical studies.

Leopold SJ, Watson JA, Jeeyapant A, Simpson JA, Phu NH, Hien TT, Day NPJ, Dondorp AM, White NJ.

PLoS Med. 2019 Aug 23;16(8):e1002858. doi: 10.1371/journal.pmed.1002858. eCollection 2019 Aug.


Enzyme Encapsulation in a Porous Hydrogen-Bonded Organic Framework.

Liang W, Carraro F, Solomon MB, Bell SG, Amenitsch H, Sumby CJ, White NG, Falcaro P, Doonan CJ.

J Am Chem Soc. 2019 Sep 11;141(36):14298-14305. doi: 10.1021/jacs.9b06589. Epub 2019 Aug 29.


The haematological consequences of Plasmodium vivax malaria after chloroquine treatment with and without primaquine: a WorldWide Antimalarial Resistance Network systematic review and individual patient data meta-analysis.

Commons RJ, Simpson JA, Thriemer K, Chu CS, Douglas NM, Abreha T, Alemu SG, Añez A, Anstey NM, Aseffa A, Assefa A, Awab GR, Baird JK, Barber BE, Borghini-Fuhrer I, D'Alessandro U, Dahal P, Daher A, de Vries PJ, Erhart A, Gomes MSM, Grigg MJ, Hwang J, Kager PA, Ketema T, Khan WA, Lacerda MVG, Leslie T, Ley B, Lidia K, Monteiro WM, Pereira DB, Phan GT, Phyo AP, Rowland M, Saravu K, Sibley CH, Siqueira AM, Stepniewska K, Taylor WRJ, Thwaites G, Tran BQ, Hien TT, Vieira JLF, Wangchuk S, Watson J, William T, Woodrow CJ, Nosten F, Guerin PJ, White NJ, Price RN.

BMC Med. 2019 Aug 1;17(1):151. doi: 10.1186/s12916-019-1386-6.


Cost-effectiveness of an environmental cleaning bundle for reducing healthcare associated infections.

White NM, Barnett AG, Hall L, Mitchell BG, Farrington A, Halton K, Paterson DL, Riley TV, Gardner A, Page K, Gericke CA, Graves N.

Clin Infect Dis. 2019 Jul 30. pii: ciz717. doi: 10.1093/cid/ciz717. [Epub ahead of print]


Determinants of dihydroartemisinin-piperaquine treatment failure in Plasmodium falciparum malaria in Cambodia, Thailand, and Vietnam: a prospective clinical, pharmacological, and genetic study.

van der Pluijm RW, Imwong M, Chau NH, Hoa NT, Thuy-Nhien NT, Thanh NV, Jittamala P, Hanboonkunupakarn B, Chutasmit K, Saelow C, Runjarern R, Kaewmok W, Tripura R, Peto TJ, Yok S, Suon S, Sreng S, Mao S, Oun S, Yen S, Amaratunga C, Lek D, Huy R, Dhorda M, Chotivanich K, Ashley EA, Mukaka M, Waithira N, Cheah PY, Maude RJ, Amato R, Pearson RD, Gonçalves S, Jacob CG, Hamilton WL, Fairhurst RM, Tarning J, Winterberg M, Kwiatkowski DP, Pukrittayakamee S, Hien TT, Day NP, Miotto O, White NJ, Dondorp AM.

Lancet Infect Dis. 2019 Sep;19(9):952-961. doi: 10.1016/S1473-3099(19)30391-3. Epub 2019 Jul 22.


Evolution and expansion of multidrug-resistant malaria in southeast Asia: a genomic epidemiology study.

Hamilton WL, Amato R, van der Pluijm RW, Jacob CG, Quang HH, Thuy-Nhien NT, Hien TT, Hongvanthong B, Chindavongsa K, Mayxay M, Huy R, Leang R, Huch C, Dysoley L, Amaratunga C, Suon S, Fairhurst RM, Tripura R, Peto TJ, Sovann Y, Jittamala P, Hanboonkunupakarn B, Pukrittayakamee S, Chau NH, Imwong M, Dhorda M, Vongpromek R, Chan XHS, Maude RJ, Pearson RD, Nguyen T, Rockett K, Drury E, Gonçalves S, White NJ, Day NP, Kwiatkowski DP, Dondorp AM, Miotto O.

Lancet Infect Dis. 2019 Sep;19(9):943-951. doi: 10.1016/S1473-3099(19)30392-5. Epub 2019 Jul 22.


Short-course primaquine for the radical cure of Plasmodium vivax malaria: a multicentre, randomised, placebo-controlled non-inferiority trial.

Taylor WRJ, Thriemer K, von Seidlein L, Yuentrakul P, Assawariyathipat T, Assefa A, Auburn S, Chand K, Chau NH, Cheah PY, Dong LT, Dhorda M, Degaga TS, Devine A, Ekawati LL, Fahmi F, Hailu A, Hasanzai MA, Hien TT, Khu H, Ley B, Lubell Y, Marfurt J, Mohammad H, Moore KA, Naddim MN, Pasaribu AP, Pasaribu S, Promnarate C, Rahim AG, Sirithiranont P, Solomon H, Sudoyo H, Sutanto I, Thanh NV, Tuyet-Trinh NT, Waithira N, Woyessa A, Yamin FY, Dondorp A, Simpson JA, Baird JK, White NJ, Day NP, Price RN.

Lancet. 2019 Sep 14;394(10202):929-938. doi: 10.1016/S0140-6736(19)31285-1. Epub 2019 Jul 18.


Regression From Prediabetes to Normal Glucose Regulation and Prevalence of Microvascular Disease in the Diabetes Prevention Program Outcomes Study (DPPOS).

Perreault L, Pan Q, Schroeder EB, Kalyani RR, Bray GA, Dagogo-Jack S, White NH, Goldberg RB, Kahn SE, Knowler WC, Mathioudakis N, Dabelea D; Diabetes Prevention Program Research Group.

Diabetes Care. 2019 Sep;42(9):1809-1815. doi: 10.2337/dc19-0244. Epub 2019 Jul 18.


Expression, purification, and characterization of a human complement component C3 analog that lacks the C-terminal C345c domain.

Ramyar KX, Xu X, White NM, Keightley A, Geisbrecht BV.

J Immunol Methods. 2019 Oct;473:112633. doi: 10.1016/j.jim.2019.07.005. Epub 2019 Jul 15.


Prognostication in palliative care.

Chu C, White N, Stone P.

Clin Med (Lond). 2019 Jul;19(4):306-310. doi: 10.7861/clinmedicine.19-4-306.


Combining antimalarial drugs and vaccine for malaria elimination campaigns: a randomized safety and immunogenicity trial of RTS,S/AS01 administered with dihydroartemisinin, piperaquine, and primaquine in healthy Thai adult volunteers.

von Seidlein L, Hanboonkunupakarn B, Jittamala P, Pongsuwan P, Chotivanich K, Tarning J, Hoglund RM, Winterberg M, Mukaka M, Peerawaranun P, Sirithiranont P, Doran Z, Ockenhouse CF, Ivinson K, Lee C, Birkett AJ, Kaslow DC, Singhasivanon P, Day NPJ, Dondorp AM, White NJ, Pukrittayakamee S.

Hum Vaccin Immunother. 2019 Aug 15:1-9. doi: 10.1080/21645515.2019.1643675. [Epub ahead of print]


Fits, faints, falls and funny turns: cost and capacity savings in Queensland from the accelerated transient attack pathway initiative (ATAP).

Blythe R, Kularatna S, White N, Graves N, Clark K, Middleton H, Grimley R.

Age Ageing. 2019 Jul 12. pii: afz086. doi: 10.1093/ageing/afz086. [Epub ahead of print]


The (un)availability of prognostic information in the last days of life: a prospective observational study.

White N, Reid F, Harries P, Harris AJL, Minton O, McGowan C, Lodge P, Tookman A, Stone P.

BMJ Open. 2019 Jul 9;9(7):e030736. doi: 10.1136/bmjopen-2019-030736.


Predicting fatigue using countermovement jump force-time signatures: PCA can distinguish neuromuscular versus metabolic fatigue.

Wu PP, Sterkenburg N, Everett K, Chapman DW, White N, Mengersen K.

PLoS One. 2019 Jul 10;14(7):e0219295. doi: 10.1371/journal.pone.0219295. eCollection 2019.


Optimal Duration of Follow-up for Assessing Antimalarial Efficacy in Pregnancy: A Retrospective Analysis of a Cohort Followed Up Until Delivery on the Thailand-Myanmar Border.

Saito M, Mansoor R, Wiladphaingern J, Paw MK, Pimanpanarak M, Proux S, Guérin PJ, White NJ, Nosten F, McGready R.

Open Forum Infect Dis. 2019 May 31;6(7):ofz264. doi: 10.1093/ofid/ofz264. eCollection 2019 Jul.


Does diabetes prevention translate into reduced long-term vascular complications of diabetes?

Nathan DM, Bennett PH, Crandall JP, Edelstein SL, Goldberg RB, Kahn SE, Knowler WC, Mather KJ, Mudaliar S, Orchard TJ, Temprosa M, White NH; Research Group.

Diabetologia. 2019 Aug;62(8):1319-1328. doi: 10.1007/s00125-019-4928-8. Epub 2019 Jul 4. Review.


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