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Intermittent dosing of the transforming growth factor beta receptor 1 inhibitor, BMS-986260, mitigates class-based cardiovascular toxicity in dogs but not rats.

Rak GD, White MR, Augustine-Rauch K, Newsome C, Graziano MJ, Schulze GE.

J Appl Toxicol. 2020 Feb 15. doi: 10.1002/jat.3954. [Epub ahead of print]


Influenza Virus Hemagglutinins H2, H5, H6, and H11 Are Not Targets of Pulmonary Surfactant Protein D: N-Glycan Subtypes in Host-Pathogen Interactions.

Parsons LM, An Y, Qi L, White MR, van der Woude R, Hartshorn KL, Taubenberger JK, de Vries RP, Cipollo JF.

J Virol. 2020 Feb 14;94(5). pii: e01951-19. doi: 10.1128/JVI.01951-19. Print 2020 Feb 14.


Enhanced Antiviral Activity of Human Surfactant Protein D by Site-Specific Engineering of the Carbohydrate Recognition Domain.

van Eijk M, Hillaire MLB, Rimmelzwaan GF, Rynkiewicz MJ, White MR, Hartshorn KL, Hessing M, Koolmees PA, Tersteeg MH, van Es MH, Meijerhof T, Huckriede A, Haagsman HP.

Front Immunol. 2019 Oct 22;10:2476. doi: 10.3389/fimmu.2019.02476. eCollection 2019.


A 48-Year-Old Man With Refractory Hypoxic Respiratory Failure.

Wiskar K, White MR, Arntfield R.

Chest. 2019 Nov;156(5):e91-e94. doi: 10.1016/j.chest.2019.05.029. No abstract available.


BCL2L1 is associated with γ-globin gene expression.

Dai Y, Shaikho EM, Perez J, Wilson CA, Liu LY, White MR, Farrell JJ, Chui DHK, Sebastiani P, Steinberg MH.

Blood Adv. 2019 Oct 22;3(20):2995-3001. doi: 10.1182/bloodadvances.2019032243.


ER stress-linked autophagy stabilizes apoptosis effector PERP and triggers its co-localization with SERCA2b at ER-plasma membrane junctions.

McDonnell SJ, Spiller DG, White MRH, Prior IA, Paraoan L.

Cell Death Discov. 2019 Sep 3;5:132. doi: 10.1038/s41420-019-0212-4. eCollection 2019.


Correction: Genotype-by-environment interactions affecting heterosis in maize.

Li Z, Coffey L, Garfin J, Miller ND, White MR, Spalding EP, Leon N, Kaeppler SM, Schnable PS, Springer NM, Hirsch CN.

PLoS One. 2019 Aug 5;14(8):e0219528. doi: 10.1371/journal.pone.0219528. eCollection 2019.


Disentangling juxtacrine from paracrine signalling in dynamic tissue.

Momiji H, Hassall KL, Featherstone K, McNamara AV, Patist AL, Spiller DG, Christian HC, White MRH, Davis JRE, Finkenstädt BF, Rand DA.

PLoS Comput Biol. 2019 Jun 13;15(6):e1007030. doi: 10.1371/journal.pcbi.1007030. eCollection 2019 Jun.


C9orf72 Poly(PR) Dipeptide Repeats Disturb Biomolecular Phase Separation and Disrupt Nucleolar Function.

White MR, Mitrea DM, Zhang P, Stanley CB, Cassidy DE, Nourse A, Phillips AH, Tolbert M, Taylor JP, Kriwacki RW.

Mol Cell. 2019 May 16;74(4):713-728.e6. doi: 10.1016/j.molcel.2019.03.019. Epub 2019 Apr 10.


Toxicity of Pexacerfont, a Corticotropin-Releasing Factor Type 1 Receptor Antagonist, in Rats and Dogs.

White MR, Graziano MJ, Sanderson TP.

Int J Toxicol. 2019 Mar/Apr;38(2):110-120. doi: 10.1177/1091581819827501. Epub 2019 Feb 13.


Human TNF-Luc reporter mouse: A new model to quantify inflammatory responses.

Minshawi F, White MRH, Muller W, Humphreys N, Jackson D, Campbell BJ, Adamson A, Papoutsopoulou S.

Sci Rep. 2019 Jan 17;9(1):193. doi: 10.1038/s41598-018-36969-x.


Working with consumers who hear voices: The experience of early career nurses in mental health services in Australia.

White MR, Stein-Parbury J, Orr F, Dawson A.

Int J Ment Health Nurs. 2019 Apr;28(2):605-615. doi: 10.1111/inm.12566. Epub 2018 Dec 17.


Selection Signatures Underlying Dramatic Male Inflorescence Transformation During Modern Hybrid Maize Breeding.

Gage JL, White MR, Edwards JW, Kaeppler S, de Leon N.

Genetics. 2018 Nov;210(3):1125-1138. doi: 10.1534/genetics.118.301487. Epub 2018 Sep 26.


Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation.

Bagnall J, Boddington C, England H, Brignall R, Downton P, Alsoufi Z, Boyd J, Rowe W, Bennett A, Walker C, Adamson A, Patel NMX, O'Cualain R, Schmidt L, Spiller DG, Jackson DA, Müller W, Muldoon M, White MRH, Paszek P.

Sci Signal. 2018 Jul 24;11(540). pii: eaaf3998. doi: 10.1126/scisignal.aaf3998.


Methods for Physical Characterization of Phase-Separated Bodies and Membrane-less Organelles.

Mitrea DM, Chandra B, Ferrolino MC, Gibbs EB, Tolbert M, White MR, Kriwacki RW.

J Mol Biol. 2018 Nov 2;430(23):4773-4805. doi: 10.1016/j.jmb.2018.07.006. Epub 2018 Jul 24. Review.


The Role and Molecular Mechanism of Action of Surfactant Protein D in Innate Host Defense Against Influenza A Virus.

Hsieh IN, De Luna X, White MR, Hartshorn KL.

Front Immunol. 2018 Jun 13;9:1368. doi: 10.3389/fimmu.2018.01368. eCollection 2018. Review.


Lectin-mediated binding and sialoglycans of porcine surfactant protein D synergistically neutralize influenza A virus.

van Eijk M, Rynkiewicz MJ, Khatri K, Leymarie N, Zaia J, White MR, Hartshorn KL, Cafarella TR, van Die I, Hessing M, Seaton BA, Haagsman HP.

J Biol Chem. 2018 Jul 6;293(27):10646-10662. doi: 10.1074/jbc.RA117.001430. Epub 2018 May 16.


Temperature regulates NF-κB dynamics and function through timing of A20 transcription.

Harper CV, Woodcock DJ, Lam C, Garcia-Albornoz M, Adamson A, Ashall L, Rowe W, Downton P, Schmidt L, West S, Spiller DG, Rand DA, White MRH.

Proc Natl Acad Sci U S A. 2018 May 29;115(22):E5243-E5249. doi: 10.1073/pnas.1803609115. Epub 2018 May 14.


Quantitative analysis reveals crosstalk mechanisms of heat shock-induced attenuation of NF-κB signaling at the single cell level.

Kardyńska M, Paszek A, Śmieja J, Spiller D, Widłak W, White MRH, Paszek P, Kimmel M.

PLoS Comput Biol. 2018 Apr 30;14(4):e1006130. doi: 10.1371/journal.pcbi.1006130. eCollection 2018 Apr.


Getting Inside the Expert's Head: An Analysis of Physician Cognitive Processes During Trauma Resuscitations.

White MR, Braund H, Howes D, Egan R, Gegenfurtner A, van Merrienboer JJG, Szulewski A.

Ann Emerg Med. 2018 Sep;72(3):289-298. doi: 10.1016/j.annemergmed.2018.03.005. Epub 2018 Apr 23.


Critical role of C-terminal residues of the Alzheimer's associated β-amyloid protein in mediating antiviral activity and modulating viral and bacterial interactions with neutrophils.

White MR, Kandel R, Hsieh IN, De Luna X, Hartshorn KL.

PLoS One. 2018 Mar 16;13(3):e0194001. doi: 10.1371/journal.pone.0194001. eCollection 2018.


Genotype-by-environment interactions affecting heterosis in maize.

Li Z, Coffey L, Garfin J, Miller ND, White MR, Spalding EP, de Leon N, Kaeppler SM, Schnable PS, Springer NM, Hirsch CN.

PLoS One. 2018 Jan 17;13(1):e0191321. doi: 10.1371/journal.pone.0191321. eCollection 2018. Erratum in: PLoS One. 2019 Aug 5;14(8):e0219528.


Live Imaging of Label-Free Graphene Oxide Reveals Critical Factors Causing Oxidative-Stress-Mediated Cellular Responses.

Vranic S, Rodrigues AF, Buggio M, Newman L, White MRH, Spiller DG, Bussy C, Kostarelos K.

ACS Nano. 2018 Feb 27;12(2):1373-1389. doi: 10.1021/acsnano.7b07734. Epub 2018 Jan 31.


Asymmetry between Activation and Deactivation during a Transcriptional Pulse.

Dunham LSS, Momiji H, Harper CV, Downton PJ, Hey K, McNamara A, Featherstone K, Spiller DG, Rand DA, Finkenstädt B, White MRH, Davis JRE.

Cell Syst. 2017 Dec 27;5(6):646-653.e5. doi: 10.1016/j.cels.2017.10.013. Epub 2017 Nov 15.


A standardized list of affect-related life events.

Cohen DJ, Barker KA, White MR.

Behav Res Methods. 2018 Oct;50(5):1806-1815. doi: 10.3758/s13428-017-0948-9.


Mitogenic stimulation accelerates influenza-induced mortality by increasing susceptibility of alveolar type II cells to infection.

Nikolaidis NM, Noel JG, Pitstick LB, Gardner JC, Uehara Y, Wu H, Saito A, Lewnard KE, Liu H, White MR, Hartshorn KL, McCormack FX.

Proc Natl Acad Sci U S A. 2017 Aug 8;114(32):E6613-E6622. doi: 10.1073/pnas.1621172114. Epub 2017 Jul 24.


Risk Factors Associated With Suicide Completions Among US Enlisted Marines.

Phillips CJ, LeardMann CA, Vyas KJ, Crum-Cianflone NF, White MR.

Am J Epidemiol. 2017 Sep 15;186(6):668-678. doi: 10.1093/aje/kwx117.


Identifying Barriers to Delivering the Awakening and Breathing Coordination, Delirium, and Early Exercise/Mobility Bundle to Minimize Adverse Outcomes for Mechanically Ventilated Patients: A Systematic Review.

Costa DK, White MR, Ginier E, Manojlovich M, Govindan S, Iwashyna TJ, Sales AE.

Chest. 2017 Aug;152(2):304-311. doi: 10.1016/j.chest.2017.03.054. Epub 2017 Apr 21. Review.


D-Glyceraldehyde-3-Phosphate Dehydrogenase Structure and Function.

White MR, Garcin ED.

Subcell Biochem. 2017;83:413-453. doi: 10.1007/978-3-319-46503-6_15. Review.


Understanding the dynamics of Toll-like Receptor 5 response to flagellin and its regulation by estradiol.

Caballero I, Boyd J, Almiñana C, Sánchez-López JA, Basatvat S, Montazeri M, Maslehat Lay N, Elliott S, Spiller DG, White MR, Fazeli A.

Sci Rep. 2017 Jan 23;7:40981. doi: 10.1038/srep40981.


Collectins, H-ficolin and LL-37 reduce influence viral replication in human monocytes and modulate virus-induced cytokine production.

White MR, Tripathi S, Verma A, Kingma P, Takahashi K, Jensenius J, Thiel S, Wang G, Crouch EC, Hartshorn KL.

Innate Immun. 2017 Jan;23(1):77-88. doi: 10.1177/1753425916678470. Epub 2016 Nov 17.


Demographic and Psychosocial Predictors of Early Attrition for Drug Use in U.S. Marines.

White MR, Phillips CJ, Vyas KJ, Bauer L.

Mil Med. 2016 Nov;181(11):e1540-e1545.


Stochasticity in the miR-9/Hes1 oscillatory network can account for clonal heterogeneity in the timing of differentiation.

Phillips NE, Manning CS, Pettini T, Biga V, Marinopoulou E, Stanley P, Boyd J, Bagnall J, Paszek P, Spiller DG, White MR, Goodfellow M, Galla T, Rattray M, Papalopulu N.

Elife. 2016 Oct 4;5. pii: e16118. doi: 10.7554/eLife.16118.


p63 is required beside p53 for PERP-mediated apoptosis in uveal melanoma.

Awais R, Spiller DG, White MR, Paraoan L.

Br J Cancer. 2016 Oct 11;115(8):983-992. doi: 10.1038/bjc.2016.269. Epub 2016 Sep 1.


The intervertebral disc contains intrinsic circadian clocks that are regulated by age and cytokines and linked to degeneration.

Dudek M, Yang N, Ruckshanthi JP, Williams J, Borysiewicz E, Wang P, Adamson A, Li J, Bateman JF, White MR, Boot-Handford RP, Hoyland JA, Meng QJ.

Ann Rheum Dis. 2017 Mar;76(3):576-584. doi: 10.1136/annrheumdis-2016-209428. Epub 2016 Aug 3.


Dynamic phosphorylation of RelA on Ser42 and Ser45 in response to TNFα stimulation regulates DNA binding and transcription.

Lanucara F, Lam C, Mann J, Monie TP, Colombo SA, Holman SW, Boyd J, Dange MC, Mann DA, White MR, Eyers CE.

Open Biol. 2016 Jul;6(7). pii: 160055. doi: 10.1098/rsob.160055.


Signal transduction controls heterogeneous NF-κB dynamics and target gene expression through cytokine-specific refractory states.

Adamson A, Boddington C, Downton P, Rowe W, Bagnall J, Lam C, Maya-Mendoza A, Schmidt L, Harper CV, Spiller DG, Rand DA, Jackson DA, White MR, Paszek P.

Nat Commun. 2016 Jul 6;7:12057. doi: 10.1038/ncomms12057.


Visualizing and Quantifying Intracellular Behavior and Abundance of the Core Circadian Clock Protein PERIOD2.

Smyllie NJ, Pilorz V, Boyd J, Meng QJ, Saer B, Chesham JE, Maywood ES, Krogager TP, Spiller DG, Boot-Handford R, White MR, Hastings MH, Loudon AS.

Curr Biol. 2016 Jul 25;26(14):1880-6. doi: 10.1016/j.cub.2016.05.018. Epub 2016 Jun 30.


Investigating IL-1β Secretion Using Real-Time Single-Cell Imaging.

Diamond C, Bagnall J, Spiller DG, White MR, Mortellaro A, Paszek P, Brough D.

Methods Mol Biol. 2016;1417:75-88. doi: 10.1007/978-1-4939-3566-6_4.


Dynamic NF-κB and E2F interactions control the priority and timing of inflammatory signalling and cell proliferation.

Ankers JM, Awais R, Jones NA, Boyd J, Ryan S, Adamson AD, Harper CV, Bridge L, Spiller DG, Jackson DA, Paszek P, Sée V, White MR.

Elife. 2016 May 17;5. pii: e10473. doi: 10.7554/eLife.10473.


Integrated Omics and Computational Glycobiology Reveal Structural Basis for Influenza A Virus Glycan Microheterogeneity and Host Interactions.

Khatri K, Klein JA, White MR, Grant OC, Leymarie N, Woods RJ, Hartshorn KL, Zaia J.

Mol Cell Proteomics. 2016 Jun;15(6):1895-912. doi: 10.1074/mcp.M116.058016. Epub 2016 Mar 16.


Spatially coordinated dynamic gene transcription in living pituitary tissue.

Featherstone K, Hey K, Momiji H, McNamara AV, Patist AL, Woodburn J, Spiller DG, Christian HC, McNeilly AS, Mullins JJ, Finkenstädt BF, Rand DA, White MR, Davis JR.

Elife. 2016 Feb 1;5:e08494. doi: 10.7554/eLife.08494.


Role of Estrogen Response Element in the Human Prolactin Gene: Transcriptional Response and Timing.

McNamara AV, Adamson AD, Dunham LS, Semprini S, Spiller DG, McNeilly AS, Mullins JJ, Davis JR, White MR.

Mol Endocrinol. 2016 Feb;30(2):189-200. doi: 10.1210/me.2015-1186. Epub 2015 Dec 21.


The sweet side of RNA regulation: glyceraldehyde-3-phosphate dehydrogenase as a noncanonical RNA-binding protein.

White MR, Garcin ED.

Wiley Interdiscip Rev RNA. 2016 Jan-Feb;7(1):53-70. doi: 10.1002/wrna.1315. Epub 2015 Nov 12. Review.


Catabolic cytokines disrupt the circadian clock and the expression of clock-controlled genes in cartilage via an NFкB-dependent pathway.

Guo B, Yang N, Borysiewicz E, Dudek M, Williams JL, Li J, Maywood ES, Adamson A, Hastings MH, Bateman JF, White MR, Boot-Handford RP, Meng QJ.

Osteoarthritis Cartilage. 2015 Nov;23(11):1981-8. doi: 10.1016/j.joca.2015.02.020.


Small-angle X-ray scattering method to characterize molecular interactions: Proof of concept.

Allec N, Choi M, Yesupriya N, Szychowski B, White MR, Kann MG, Garcin ED, Daniel MC, Badano A.

Sci Rep. 2015 Jul 10;5:12085. doi: 10.1038/srep12085.


Quantitative dynamic imaging of immune cell signalling using lentiviral gene transfer.

Bagnall J, Boddington C, Boyd J, Brignall R, Rowe W, Jones NA, Schmidt L, Spiller DG, White MR, Paszek P.

Integr Biol (Camb). 2015 Jun;7(6):713-25. doi: 10.1039/c5ib00067j. Epub 2015 May 20.


Glucocorticoid receptor regulates accurate chromosome segregation and is associated with malignancy.

Matthews LC, Berry AA, Morgan DJ, Poolman TM, Bauer K, Kramer F, Spiller DG, Richardson RV, Chapman KE, Farrow SN, Norman MR, Williamson AJ, Whetton AD, Taylor SS, Tuckermann JP, White MR, Ray DW.

Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):5479-84. doi: 10.1073/pnas.1411356112. Epub 2015 Apr 6.


A stochastic transcriptional switch model for single cell imaging data.

Hey KL, Momiji H, Featherstone K, Davis JR, White MR, Rand DA, Finkenstädt B.

Biostatistics. 2015 Oct;16(4):655-69. doi: 10.1093/biostatistics/kxv010. Epub 2015 Mar 26.


Smoking cessation and improvement in physical performance among young men.

Feinberg JH, Ryan MA, Johns M, Marvin BA, Reading JE, White MR.

Mil Med. 2015 Mar;180(3):343-9. doi: 10.7205/MILMED-D-14-00370.


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