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Items: 1 to 50 of 200

1.

Human Organoids Share Structural and Genetic Features with Primary Pancreatic Adenocarcinoma Tumors.

Romero-Calvo I, Weber C, Ray M, Brown M, Kirby K, Nandi RK, Long TM, Sparrow SM, Ugolkov A, Qiang W, Zhang Y, Brunetti T, Kindler H, Segal JP, Rzhetsky A, Mazar AP, Buschmann MM, Weichselbaum R, Roggin K, White KP.

Mol Cancer Res. 2018 Aug 31. pii: molcanres.0531.2018. doi: 10.1158/1541-7786.MCR-18-0531. [Epub ahead of print]

PMID:
30171177
2.

Evaluation of chromatin accessibility in prefrontal cortex of individuals with schizophrenia.

Bryois J, Garrett ME, Song L, Safi A, Giusti-Rodriguez P, Johnson GD, Shieh AW, Buil A, Fullard JF, Roussos P, Sklar P, Akbarian S, Haroutunian V, Stockmeier CA, Wray GA, White KP, Liu C, Reddy TE, Ashley-Koch A, Sullivan PF, Crawford GE.

Nat Commun. 2018 Aug 7;9(1):3121. doi: 10.1038/s41467-018-05379-y.

3.

Red-brown plaque on the leg.

Liu M, White KP, Funk T.

Cutis. 2018 Jun;101(6):400;405;406. No abstract available.

PMID:
30063779
4.

Clinical validation of the Tempus xO assay.

Beaubier N, Tell R, Huether R, Bontrager M, Bush S, Parsons J, Shah K, Baker T, Selkov G, Taxter T, Thomas A, Bettis S, Khan A, Lau D, Lee C, Barber M, Cieslik M, Frankenberger C, Franzen A, Weiner A, Palmer G, Lonigro R, Robinson D, Wu YM, Cao X, Lefkofsky E, Chinnaiyan A, White KP.

Oncotarget. 2018 May 25;9(40):25826-25832. doi: 10.18632/oncotarget.25381. eCollection 2018 May 25.

5.

Integrated molecular subtyping defines a curable oligometastatic state in colorectal liver metastasis.

Pitroda SP, Khodarev NN, Huang L, Uppal A, Wightman SC, Ganai S, Joseph N, Pitt J, Brown M, Forde M, Mangold K, Xue L, Weber C, Segal JP, Kadri S, Stack ME, Khan S, Paty P, Kaul K, Andrade J, White KP, Talamonti M, Posner MC, Hellman S, Weichselbaum RR.

Nat Commun. 2018 May 4;9(1):1793. doi: 10.1038/s41467-018-04278-6.

6.

Author Correction to: Dynamic Scheduling for Veterans Health Administration Patients Using Geospatial Dynamic Overbooking.

Adams S, Scherer WT, White KP Jr, Payne J, Hernandez O, Gerber MS, Whitehead NP.

J Med Syst. 2018 Mar 6;42(4):73. doi: 10.1007/s10916-018-0924-7.

PMID:
29511944
7.

Photosensitive Eruption in a Patient with Metastatic Non-small Cell Lung Cancer: Challenge.

Knapp C 3rd, White KP, Fett N.

Am J Dermatopathol. 2018 Feb 27. doi: 10.1097/DAD.0000000000001119. [Epub ahead of print] No abstract available.

PMID:
29494355
8.

Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap.

Gandal MJ, Haney JR, Parikshak NN, Leppa V, Ramaswami G, Hartl C, Schork AJ, Appadurai V, Buil A, Werge TM, Liu C, White KP; CommonMind Consortium; PsychENCODE Consortium; iPSYCH-BROAD Working Group, Horvath S, Geschwind DH.

Science. 2018 Feb 9;359(6376):693-697. doi: 10.1126/science.aad6469.

9.

The ModERN Resource: Genome-Wide Binding Profiles for Hundreds of Drosophila and Caenorhabditis elegans Transcription Factors.

Kudron MM, Victorsen A, Gevirtzman L, Hillier LW, Fisher WW, Vafeados D, Kirkey M, Hammonds AS, Gersch J, Ammouri H, Wall ML, Moran J, Steffen D, Szynkarek M, Seabrook-Sturgis S, Jameel N, Kadaba M, Patton J, Terrell R, Corson M, Durham TJ, Park S, Samanta S, Han M, Xu J, Yan KK, Celniker SE, White KP, Ma L, Gerstein M, Reinke V, Waterston RH.

Genetics. 2018 Mar;208(3):937-949. doi: 10.1534/genetics.117.300657. Epub 2017 Dec 28.

PMID:
29284660
10.

Nuclear receptors in cancer - uncovering new and evolving roles through genomic analysis.

Dhiman VK, Bolt MJ, White KP.

Nat Rev Genet. 2018 Mar;19(3):160-174. doi: 10.1038/nrg.2017.102. Epub 2017 Dec 27. Review.

PMID:
29279606
11.

Functional assessment of human enhancer activities using whole-genome STARR-sequencing.

Liu Y, Yu S, Dhiman VK, Brunetti T, Eckart H, White KP.

Genome Biol. 2017 Nov 20;18(1):219. doi: 10.1186/s13059-017-1345-5.

12.

Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors.

Cheng J, Demeulemeester J, Wedge DC, Vollan HKM, Pitt JJ, Russnes HG, Pandey BP, Nilsen G, Nord S, Bignell GR, White KP, Børresen-Dale AL, Campbell PJ, Kristensen VN, Stratton MR, Lingjærde OC, Moreau Y, Van Loo P.

Nat Commun. 2017 Oct 31;8(1):1221. doi: 10.1038/s41467-017-01355-0.

13.

Systematic identification of regulatory variants associated with cancer risk.

Liu S, Liu Y, Zhang Q, Wu J, Liang J, Yu S, Wei GH, White KP, Wang X.

Genome Biol. 2017 Oct 23;18(1):194. doi: 10.1186/s13059-017-1322-z.

14.

Dynamic Scheduling for Veterans Health Administration Patients using Geospatial Dynamic Overbooking.

Adams S, Scherer WT, White KP Jr, Payne J, Hernandez O, Gerber MS, Whitehead NP.

J Med Syst. 2017 Oct 12;41(11):182. doi: 10.1007/s10916-017-0815-3. Erratum in: J Med Syst. 2018 Mar 6;42(4):73.

PMID:
29027078
15.

Identification of Novel Protein Expression Changes Following Cisplatin Treatment and Application to Combination Therapy.

Stark AL, Madian AG, Williams SW, Chen V, Wing C, Hause RJ Jr, To LA, Gill AL, Myers JL, Gorsic LK, Ciaccio MF, White KP, Jones RB, Dolan ME.

J Proteome Res. 2017 Nov 3;16(11):4227-4236. doi: 10.1021/acs.jproteome.7b00576. Epub 2017 Sep 29.

PMID:
28902521
16.

Assessing Genetic Expression Profiles in Melanoma Diagnosis.

Leachman SA, Mengden Koon S, Korcheva VB, White KP.

Dermatol Clin. 2017 Oct;35(4):537-544. doi: 10.1016/j.det.2017.06.016. Epub 2017 Aug 7. Review.

17.

Cutaneous Small-Vessel Vasculitis in Two Children with Inflammatory Bowel Disease: Case Series and Review of the Literature.

Ho T, Orenstein LAV, Boos MD, White KP, Fett N.

Pediatr Dermatol. 2017 Sep;34(5):e235-e240. doi: 10.1111/pde.13218. Epub 2017 Aug 2. Review.

PMID:
28771805
18.

Isoradiotopic response of lichen planus after radiotherapy of the breast.

Hopkins AM, White KP, Simpson EL.

JAAD Case Rep. 2017 May 17;3(3):246-249. doi: 10.1016/j.jdcr.2017.02.023. eCollection 2017 May. No abstract available.

19.

Robust stratification of breast cancer subtypes using differential patterns of transcript isoform expression.

Stricker TP, Brown CD, Bandlamudi C, McNerney M, Kittler R, Montoya V, Peterson A, Grossman R, White KP.

PLoS Genet. 2017 Mar 6;13(3):e1006589. doi: 10.1371/journal.pgen.1006589. eCollection 2017 Mar.

20.

Integration of temporal and spatial patterning generates neural diversity.

Erclik T, Li X, Courgeon M, Bertet C, Chen Z, Baumert R, Ng J, Koo C, Arain U, Behnia R, del Valle Rodriguez A, Senderowicz L, Negre N, White KP, Desplan C.

Nature. 2017 Jan 19;541(7637):365-370. doi: 10.1038/nature20794. Epub 2017 Jan 11.

21.

Evolution of transcript modification by N6-methyladenosine in primates.

Ma L, Zhao B, Chen K, Thomas A, Tuteja JH, He X, He C, White KP.

Genome Res. 2017 Mar;27(3):385-392. doi: 10.1101/gr.212563.116. Epub 2017 Jan 4.

22.

Tracing the origin of disseminated tumor cells in breast cancer using single-cell sequencing.

Demeulemeester J, Kumar P, Møller EK, Nord S, Wedge DC, Peterson A, Mathiesen RR, Fjelldal R, Zamani Esteki M, Theunis K, Fernandez Gallardo E, Grundstad AJ, Borgen E, Baumbusch LO, Børresen-Dale AL, White KP, Kristensen VN, Van Loo P, Voet T, Naume B.

Genome Biol. 2016 Dec 9;17(1):250.

23.

Clinical Validation of a Next-Generation Sequencing Genomic Oncology Panel via Cross-Platform Benchmarking against Established Amplicon Sequencing Assays.

Kadri S, Long BC, Mujacic I, Zhen CJ, Wurst MN, Sharma S, McDonald N, Niu N, Benhamed S, Tuteja JH, Seiwert TY, White KP, McNerney ME, Fitzpatrick C, Wang YL, Furtado LV, Segal JP.

J Mol Diagn. 2017 Jan;19(1):43-56. doi: 10.1016/j.jmoldx.2016.07.012. Epub 2016 Nov 9.

PMID:
27836695
24.

Nicolau syndrome and localized panniculitis: a report of dual diagnoses with an emphasis on morphea profunda-like changes following injection with glatiramer acetate.

Mott SE, Peña ZG, Spain RI, White KP, Ehst BD.

J Cutan Pathol. 2016 Nov;43(11):1056-1061. doi: 10.1111/cup.12791. Epub 2016 Sep 8.

PMID:
27516414
25.

Metabolic Regulation of Gene Expression by Histone Lysine β-Hydroxybutyrylation.

Xie Z, Zhang D, Chung D, Tang Z, Huang H, Dai L, Qi S, Li J, Colak G, Chen Y, Xia C, Peng C, Ruan H, Kirkey M, Wang D, Jensen LM, Kwon OK, Lee S, Pletcher SD, Tan M, Lombard DB, White KP, Zhao H, Li J, Roeder RG, Yang X, Zhao Y.

Mol Cell. 2016 Apr 21;62(2):194-206. doi: 10.1016/j.molcel.2016.03.036.

26.

The PsychENCODE project.

PsychENCODE Consortium, Akbarian S, Liu C, Knowles JA, Vaccarino FM, Farnham PJ, Crawford GE, Jaffe AE, Pinto D, Dracheva S, Geschwind DH, Mill J, Nairn AC, Abyzov A, Pochareddy S, Prabhakar S, Weissman S, Sullivan PF, State MW, Weng Z, Peters MA, White KP, Gerstein MB, Amiri A, Armoskus C, Ashley-Koch AE, Bae T, Beckel-Mitchener A, Berman BP, Coetzee GA, Coppola G, Francoeur N, Fromer M, Gao R, Grennan K, Herstein J, Kavanagh DH, Ivanov NA, Jiang Y, Kitchen RR, Kozlenkov A, Kundakovic M, Li M, Li Z, Liu S, Mangravite LM, Mattei E, Markenscoff-Papadimitriou E, Navarro FC, North N, Omberg L, Panchision D, Parikshak N, Poschmann J, Price AJ, Purcaro M, Reddy TE, Roussos P, Schreiner S, Scuderi S, Sebra R, Shibata M, Shieh AW, Skarica M, Sun W, Swarup V, Thomas A, Tsuji J, van Bakel H, Wang D, Wang Y, Wang K, Werling DM, Willsey AJ, Witt H, Won H, Wong CC, Wray GA, Wu EY, Xu X, Yao L, Senthil G, Lehner T, Sklar P, Sestan N.

Nat Neurosci. 2015 Dec;18(12):1707-12. doi: 10.1038/nn.4156. Review. No abstract available.

27.

Shared Genetic Signals of Hypoxia Adaptation in Drosophila and in High-Altitude Human Populations.

Jha AR, Zhou D, Brown CD, Kreitman M, Haddad GG, White KP.

Mol Biol Evol. 2016 Feb;33(2):501-17. doi: 10.1093/molbev/msv248. Epub 2015 Nov 17.

28.

Centrosomin represses dendrite branching by orienting microtubule nucleation.

Yalgin C, Ebrahimi S, Delandre C, Yoong LF, Akimoto S, Tran H, Amikura R, Spokony R, Torben-Nielsen B, White KP, Moore AW.

Nat Neurosci. 2015 Oct;18(10):1437-45. doi: 10.1038/nn.4099. Epub 2015 Aug 31.

PMID:
26322925
29.

A Conserved Bicycle Model for Circadian Clock Control of Membrane Excitability.

Flourakis M, Kula-Eversole E, Hutchison AL, Han TH, Aranda K, Moose DL, White KP, Dinner AR, Lear BC, Ren D, Diekman CO, Raman IM, Allada R.

Cell. 2015 Aug 13;162(4):836-48. doi: 10.1016/j.cell.2015.07.036.

30.

Regulation of Gene Expression Patterns in Mosquito Reproduction.

Roy S, Saha TT, Johnson L, Zhao B, Ha J, White KP, Girke T, Zou Z, Raikhel AS.

PLoS Genet. 2015 Aug 14;11(8):e1005450. doi: 10.1371/journal.pgen.1005450. eCollection 2015 Aug.

31.

Whole-Genome Resequencing of Experimental Populations Reveals Polygenic Basis of Egg-Size Variation in Drosophila melanogaster.

Jha AR, Miles CM, Lippert NR, Brown CD, White KP, Kreitman M.

Mol Biol Evol. 2015 Oct;32(10):2616-32. doi: 10.1093/molbev/msv136. Epub 2015 Jun 3.

32.

Zodiac: A Comprehensive Depiction of Genetic Interactions in Cancer by Integrating TCGA Data.

Zhu Y, Xu Y, Helseth DL Jr, Gulukota K, Yang S, Pesce LL, Mitra R, Müller P, Sengupta S, Guo W, Silverstein JC, Foster I, Parsad N, White KP, Ji Y.

J Natl Cancer Inst. 2015 May 8;107(8). pii: djv129. doi: 10.1093/jnci/djv129. Print 2015 Aug.

33.

Integrative analysis of head and neck cancer identifies two biologically distinct HPV and three non-HPV subtypes.

Keck MK, Zuo Z, Khattri A, Stricker TP, Brown CD, Imanguli M, Rieke D, Endhardt K, Fang P, Brägelmann J, DeBoer R, El-Dinali M, Aktolga S, Lei Z, Tan P, Rozen SG, Salgia R, Weichselbaum RR, Lingen MW, Story MD, Ang KK, Cohen EE, White KP, Vokes EE, Seiwert TY.

Clin Cancer Res. 2015 Feb 15;21(4):870-81. doi: 10.1158/1078-0432.CCR-14-2481. Epub 2014 Dec 9.

34.

Widespread genetic epistasis among cancer genes.

Wang X, Fu AQ, McNerney ME, White KP.

Nat Commun. 2014 Nov 19;5:4828. doi: 10.1038/ncomms5828.

PMID:
25407795
35.

A novel mechanism of inherited TBG deficiency: mutation in a liver-specific enhancer.

Ferrara AM, Pappa T, Fu J, Brown CD, Peterson A, Moeller LC, Wyne K, White KP, Pluzhnikov A, Trubetskoy V, Nobrega M, Weiss RE, Dumitrescu AM, Refetoff S.

J Clin Endocrinol Metab. 2015 Jan;100(1):E173-81. doi: 10.1210/jc.2014-3490.

36.

Syringoid eccrine carcinoma of the eyelid presenting as cicatricial entropion.

Shah MM, Steele EA, White KP, Wilson DJ.

Int J Ophthalmol. 2014 Oct 18;7(5):912-3. doi: 10.3980/j.issn.2222-3959.2014.05.31. eCollection 2014. No abstract available.

37.

Pri peptides are mediators of ecdysone for the temporal control of development.

Chanut-Delalande H, Hashimoto Y, Pelissier-Monier A, Spokony R, Dib A, Kondo T, Bohère J, Niimi K, Latapie Y, Inagaki S, Dubois L, Valenti P, Polesello C, Kobayashi S, Moussian B, White KP, Plaza S, Kageyama Y, Payre F.

Nat Cell Biol. 2014 Nov;16(11):1035-44. doi: 10.1038/ncb3052. Epub 2014 Oct 26.

PMID:
25344753
38.

Su(H)-mediated repression positions gene boundaries along the dorsal-ventral axis of Drosophila embryos.

Ozdemir A, Ma L, White KP, Stathopoulos A.

Dev Cell. 2014 Oct 13;31(1):100-13. doi: 10.1016/j.devcel.2014.08.005.

39.

Reply to Brunet and Doolittle: Both selected effect and causal role elements can influence human biology and disease.

Kellis M, Wold B, Snyder MP, Bernstein BE, Kundaje A, Marinov GK, Ward LD, Birney E, Crawford GE, Dekker J, Dunham I, Elnitski LL, Farnham PJ, Feingold EA, Gerstein M, Giddings MC, Gilbert DM, Gingeras TR, Green ED, Guigo R, Hubbard T, Kent J, Lieb JD, Myers RM, Pazin MJ, Ren B, Stamatoyannopoulos J, Weng Z, White KP, Hardison RC.

Proc Natl Acad Sci U S A. 2014 Aug 19;111(33):E3366. No abstract available.

40.

Rare occurrence of EGFRvIII deletion in head and neck squamous cell carcinoma.

Khattri A, Zuo Z, Brägelmann J, Keck MK, El Dinali M, Brown CD, Stricker T, Munagala A, Cohen EE, Lingen MW, White KP, Vokes EE, Seiwert TY.

Oral Oncol. 2015 Jan;51(1):53-8. doi: 10.1016/j.oraloncology.2014.08.014. Epub 2014 Sep 23.

PMID:
25255959
41.

Transcription factor networks in Drosophila melanogaster.

Rhee DY, Cho DY, Zhai B, Slattery M, Ma L, Mintseris J, Wong CY, White KP, Celniker SE, Przytycka TM, Gygi SP, Obar RA, Artavanis-Tsakonas S.

Cell Rep. 2014 Sep 25;8(6):2031-2043. doi: 10.1016/j.celrep.2014.08.038. Epub 2014 Sep 18.

42.

Comparative analysis of regulatory information and circuits across distant species.

Boyle AP, Araya CL, Brdlik C, Cayting P, Cheng C, Cheng Y, Gardner K, Hillier LW, Janette J, Jiang L, Kasper D, Kawli T, Kheradpour P, Kundaje A, Li JJ, Ma L, Niu W, Rehm EJ, Rozowsky J, Slattery M, Spokony R, Terrell R, Vafeados D, Wang D, Weisdepp P, Wu YC, Xie D, Yan KK, Feingold EA, Good PJ, Pazin MJ, Huang H, Bickel PJ, Brenner SE, Reinke V, Waterston RH, Gerstein M, White KP, Kellis M, Snyder M.

Nature. 2014 Aug 28;512(7515):453-6. doi: 10.1038/nature13668.

43.

Identification and validation of genetic variants that influence transcription factor and cell signaling protein levels.

Hause RJ, Stark AL, Antao NN, Gorsic LK, Chung SH, Brown CD, Wong SS, Gill DF, Myers JL, To LA, White KP, Dolan ME, Jones RB.

Am J Hum Genet. 2014 Aug 7;95(2):194-208. doi: 10.1016/j.ajhg.2014.07.005. Epub 2014 Jul 31.

44.

Integrative and comparative genomic analysis of HPV-positive and HPV-negative head and neck squamous cell carcinomas.

Seiwert TY, Zuo Z, Keck MK, Khattri A, Pedamallu CS, Stricker T, Brown C, Pugh TJ, Stojanov P, Cho J, Lawrence MS, Getz G, Brägelmann J, DeBoer R, Weichselbaum RR, Langerman A, Portugal L, Blair E, Stenson K, Lingen MW, Cohen EE, Vokes EE, White KP, Hammerman PS.

Clin Cancer Res. 2015 Feb 1;21(3):632-41. doi: 10.1158/1078-0432.CCR-13-3310. Epub 2014 Jul 23.

45.

Nfkb1 is a haploinsufficient DNA damage-specific tumor suppressor.

Voce DJ, Schmitt AM, Uppal A, McNerney ME, Bernal GM, Cahill KE, Wahlstrom JS, Nassiri A, Yu X, Crawley CD, White KP, Onel K, Weichselbaum RR, Yamini B.

Oncogene. 2015 May 21;34(21):2807-13. doi: 10.1038/onc.2014.211. Epub 2014 Jul 21.

46.

Yorkie promotes transcription by recruiting a histone methyltransferase complex.

Oh H, Slattery M, Ma L, White KP, Mann RS, Irvine KD.

Cell Rep. 2014 Jul 24;8(2):449-59. doi: 10.1016/j.celrep.2014.06.017. Epub 2014 Jul 10.

47.

Diverse patterns of genomic targeting by transcriptional regulators in Drosophila melanogaster.

Slattery M, Ma L, Spokony RF, Arthur RK, Kheradpour P, Kundaje A, Nègre N, Crofts A, Ptashkin R, Zieba J, Ostapenko A, Suchy S, Victorsen A, Jameel N, Grundstad AJ, Gao W, Moran JR, Rehm EJ, Grossman RL, Kellis M, White KP.

Genome Res. 2014 Jul;24(7):1224-35. doi: 10.1101/gr.168807.113.

48.

Evolution of H3K27me3-marked chromatin is linked to gene expression evolution and to patterns of gene duplication and diversification.

Arthur RK, Ma L, Slattery M, Spokony RF, Ostapenko A, Nègre N, White KP.

Genome Res. 2014 Jul;24(7):1115-24. doi: 10.1101/gr.162008.113.

49.

The spectrum of somatic mutations in high-risk acute myeloid leukaemia with -7/del(7q).

McNerney ME, Brown CD, Peterson AL, Banerjee M, Larson RA, Anastasi J, Le Beau MM, White KP.

Br J Haematol. 2014 Aug;166(4):550-6. doi: 10.1111/bjh.12964. Epub 2014 Jun 13.

50.

Low-grade prostate cancer diverges early from high grade and metastatic disease.

VanderWeele DJ, Brown CD, Taxy JB, Gillard M, Hatcher DM, Tom WR, Stadler WM, White KP.

Cancer Sci. 2014 Aug;105(8):1079-85. doi: 10.1111/cas.12460.

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