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Items: 1 to 50 of 186

1.

Sustained Klotho delivery reduces serum phosphate in a model of diabetic nephropathy.

Hum JM, O'Bryan LM, Tatiparthi AK, Clinkenbeard EL, Ni P, Cramer MS, Bhaskaran M, Johnson RL, Wilson JM, Smith RC, White KE.

J Appl Physiol (1985). 2019 Jan 3. doi: 10.1152/japplphysiol.00838.2018. [Epub ahead of print]

PMID:
30605400
2.

Controlling, Understanding, and Redirecting the Thermal Rearrangement of 3,3-Dicyano-1,5-enynes.

Scott SK, Sanders JN, White KE, Yu RA, Houk KN, Grenning AJ.

J Am Chem Soc. 2018 Nov 28;140(47):16134-16139. doi: 10.1021/jacs.8b08553. Epub 2018 Nov 12.

PMID:
30379070
3.

Pharmacological management of X-linked hypophosphataemia.

Imel EA, White KE.

Br J Clin Pharmacol. 2018 Sep 29. doi: 10.1111/bcp.13763. [Epub ahead of print] Review.

PMID:
30207609
4.

Vangl2, a planar cell polarity molecule, is implicated in irreversible and reversible kidney glomerular injury.

Papakrivopoulou E, Vasilopoulou E, Lindenmeyer MT, Pacheco S, Brzóska HŁ, Price KL, Kolatsi-Joannou M, White KE, Henderson DJ, Dean CH, Cohen CD, Salama AD, Woolf AS, Long DA.

J Pathol. 2018 Dec;246(4):485-496. doi: 10.1002/path.5158.

5.

Shifts in podocyte histone H3K27me3 regulate mouse and human glomerular disease.

Majumder S, Thieme K, Batchu SN, Alghamdi TA, Bowskill BB, Kabir MG, Liu Y, Advani SL, White KE, Geldenhuys L, Tennankore KK, Poyah P, Siddiqi FS, Advani A.

J Clin Invest. 2018 Jan 2;128(1):483-499. doi: 10.1172/JCI95946. Epub 2017 Dec 11.

6.

Osteoglophonic Dysplasia: Phenotypic and Radiological Clues.

Kuthiroly S, Yesodharan D, Ghosh A, White KE, Nampoothiri S.

J Pediatr Genet. 2017 Dec;6(4):247-251. doi: 10.1055/s-0037-1602816. Epub 2017 May 5.

7.

Erythropoietin stimulates murine and human fibroblast growth factor-23, revealing novel roles for bone and bone marrow.

Clinkenbeard EL, Hanudel MR, Stayrook KR, Appaiah HN, Farrow EG, Cass TA, Summers LJ, Ip CS, Hum JM, Thomas JC, Ivan M, Richine BM, Chan RJ, Clemens TL, Schipani E, Sabbagh Y, Xu L, Srour EF, Alvarez MB, Kacena MA, Salusky IB, Ganz T, Nemeth E, White KE.

Haematologica. 2017 Nov;102(11):e427-e430. doi: 10.3324/haematol.2017.167882. Epub 2017 Aug 17. No abstract available.

8.

Janus Kinase 2 Regulates Transcription Factor EB Expression and Autophagy Completion in Glomerular Podocytes.

Alghamdi TA, Majumder S, Thieme K, Batchu SN, White KE, Liu Y, Brijmohan AS, Bowskill BB, Advani SL, Woo M, Advani A.

J Am Soc Nephrol. 2017 Sep;28(9):2641-2653. doi: 10.1681/ASN.2016111208. Epub 2017 Apr 19.

9.

The metabolic bone disease associated with the Hyp mutation is independent of osteoblastic HIF1α expression.

Hum JM, Clinkenbeard EL, Ip C, Cass TA, Allen M, White KE.

Bone Rep. 2017 Jan 17;6:38-43. doi: 10.1016/j.bonr.2017.01.003. eCollection 2017 Jun.

10.

Acute Parathyroid Hormone Injection Increases C-Terminal but Not Intact Fibroblast Growth Factor 23 Levels.

Knab VM, Corbin B, Andrukhova O, Hum JM, Ni P, Rabadi S, Maeda A, White KE, Erben RG, Jüppner H, Christov M.

Endocrinology. 2017 May 1;158(5):1130-1139. doi: 10.1210/en.2016-1451.

11.

Heritable and acquired disorders of phosphate metabolism: Etiologies involving FGF23 and current therapeutics.

Clinkenbeard EL, White KE.

Bone. 2017 Sep;102:31-39. doi: 10.1016/j.bone.2017.01.034. Epub 2017 Jan 31. Review.

12.

Novel functions of circulating Klotho.

Hum JM, O'Bryan L, Smith RC, White KE.

Bone. 2017 Jul;100:36-40. doi: 10.1016/j.bone.2016.11.025. Epub 2016 Nov 23. Review.

13.

Chronic Hyperphosphatemia and Vascular Calcification Are Reduced by Stable Delivery of Soluble Klotho.

Hum JM, O'Bryan LM, Tatiparthi AK, Cass TA, Clinkenbeard EL, Cramer MS, Bhaskaran M, Johnson RL, Wilson JM, Smith RC, White KE.

J Am Soc Nephrol. 2017 Apr;28(4):1162-1174. doi: 10.1681/ASN.2015111266. Epub 2016 Nov 11.

14.

Phenotypic and Genotypic Characterization and Treatment of a Cohort With Familial Tumoral Calcinosis/Hyperostosis-Hyperphosphatemia Syndrome.

Ramnitz MS, Gourh P, Goldbach-Mansky R, Wodajo F, Ichikawa S, Econs MJ, White KE, Molinolo A, Chen MY, Heller T, Del Rivero J, Seo-Mayer P, Arabshahi B, Jackson MB, Hatab S, McCarthy E, Guthrie LC, Brillante BA, Gafni RI, Collins MT.

J Bone Miner Res. 2016 Oct;31(10):1845-1854. doi: 10.1002/jbmr.2870. Epub 2016 Sep 20.

15.

Loss of endogenous thymosin β4 accelerates glomerular disease.

Vasilopoulou E, Kolatsi-Joannou M, Lindenmeyer MT, White KE, Robson MG, Cohen CD, Sebire NJ, Riley PR, Winyard PJ, Long DA.

Kidney Int. 2016 Nov;90(5):1056-1070. doi: 10.1016/j.kint.2016.06.032. Epub 2016 Aug 26.

16.

Systemic Control of Bone Homeostasis by FGF23 Signaling.

Clinkenbeard EL, White KE.

Curr Mol Biol Rep. 2016 Mar 1;2(1):62-71. Epub 2016 Feb 3.

17.

Excessive Osteocytic Fgf23 Secretion Contributes to Pyrophosphate Accumulation and Mineralization Defect in Hyp Mice.

Murali SK, Andrukhova O, Clinkenbeard EL, White KE, Erben RG.

PLoS Biol. 2016 Apr 1;14(4):e1002427. doi: 10.1371/journal.pbio.1002427. eCollection 2016 Apr.

18.

Prostaglandin I2 Receptor Agonism Preserves β-Cell Function and Attenuates Albuminuria Through Nephrin-Dependent Mechanisms.

Batchu SN, Majumder S, Bowskill BB, White KE, Advani SL, Brijmohan AS, Liu Y, Thai K, Azizi PM, Lee WL, Advani A.

Diabetes. 2016 May;65(5):1398-409. doi: 10.2337/db15-0783. Epub 2016 Feb 11.

19.

Conditional Deletion of Murine Fgf23: Interruption of the Normal Skeletal Responses to Phosphate Challenge and Rescue of Genetic Hypophosphatemia.

Clinkenbeard EL, Cass TA, Ni P, Hum JM, Bellido T, Allen MR, White KE.

J Bone Miner Res. 2016 Jun;31(6):1247-57. doi: 10.1002/jbmr.2792. Epub 2016 Mar 4.

20.

Gene-by-Diet Interactions Affect Serum 1,25-Dihydroxyvitamin D Levels in Male BXD Recombinant Inbred Mice.

Fleet JC, Replogle RA, Reyes-Fernandez P, Wang L, Zhang M, Clinkenbeard EL, White KE.

Endocrinology. 2016 Feb;157(2):470-81. doi: 10.1210/en.2015-1786. Epub 2015 Nov 20.

21.

The Histone Methyltransferase Enzyme Enhancer of Zeste Homolog 2 Protects against Podocyte Oxidative Stress and Renal Injury in Diabetes.

Siddiqi FS, Majumder S, Thai K, Abdalla M, Hu P, Advani SL, White KE, Bowskill BB, Guarna G, Dos Santos CC, Connelly KA, Advani A.

J Am Soc Nephrol. 2016 Jul;27(7):2021-34. doi: 10.1681/ASN.2014090898. Epub 2015 Nov 3.

22.

Ciliary neurotrophic factor has intrinsic and extrinsic roles in regulating B cell differentiation and bone structure.

Askmyr M, White KE, Jovic T, King HA, Quach JM, Maluenda AC, Baker EK, Smeets MF, Walkley CR, Purton LE.

Sci Rep. 2015 Oct 21;5:15529. doi: 10.1038/srep15529.

23.

CXCR4 promotes renal tubular cell survival in male diabetic rats: implications for ligand inactivation in the human kidney.

Siddiqi FS, Chen LH, Advani SL, Thai K, Batchu SN, Alghamdi TA, White KE, Sood MM, Gibson IW, Connelly KA, Marsden PA, Advani A.

Endocrinology. 2015 Mar;156(3):1121-32. doi: 10.1210/en.2014-1650. Epub 2014 Dec 30.

PMID:
25549045
24.

Genetic rescue of glycosylation-deficient Fgf23 in the Galnt3 knockout mouse.

Ichikawa S, Gray AK, Padgett LR, Allen MR, Clinkenbeard EL, Sarpa NM, White KE, Econs MJ.

Endocrinology. 2014 Oct;155(10):3891-8. doi: 10.1210/en.2014-1199. Epub 2014 Jul 22.

25.

Hypophosphatemic rickets: revealing novel control points for phosphate homeostasis.

White KE, Hum JM, Econs MJ.

Curr Osteoporos Rep. 2014 Sep;12(3):252-62. doi: 10.1007/s11914-014-0223-2. Review.

26.

Coupling fibroblast growth factor 23 production and cleavage: iron deficiency, rickets, and kidney disease.

Wolf M, White KE.

Curr Opin Nephrol Hypertens. 2014 Jul;23(4):411-9. doi: 10.1097/01.mnh.0000447020.74593.6f. Review.

27.

Dynamic regulation of FGF23 by Fam20C phosphorylation, GalNAc-T3 glycosylation, and furin proteolysis.

Tagliabracci VS, Engel JL, Wiley SE, Xiao J, Gonzalez DJ, Nidumanda Appaiah H, Koller A, Nizet V, White KE, Dixon JE.

Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):5520-5. doi: 10.1073/pnas.1402218111. Epub 2014 Mar 26.

28.

Hyperphosphatemic familial tumoral calcinosis: response to acetazolamide and postulated mechanisms.

Finer G, Price HE, Shore RM, White KE, Langman CB.

Am J Med Genet A. 2014 Jun;164A(6):1545-9. doi: 10.1002/ajmg.a.36476. Epub 2014 Mar 25.

PMID:
24668887
29.

Urokinase-type plasminogen activator receptor (uPAR) ligation induces a raft-localized integrin signaling switch that mediates the hypermotile phenotype of fibrotic fibroblasts.

Grove LM, Southern BD, Jin TH, White KE, Paruchuri S, Harel E, Wei Y, Rahaman SO, Gladson CL, Ding Q, Craik CS, Chapman HA, Olman MA.

J Biol Chem. 2014 May 2;289(18):12791-804. doi: 10.1074/jbc.M113.498576. Epub 2014 Mar 18.

30.

Smoking behavior and motivation to quit among chronic pain patients initiating multidisciplinary pain treatment: a prospective study.

Unrod M, Gironda RJ, Clark ME, White KE, Simmons VN, Sutton SK, Brandon TH.

Pain Med. 2014 Aug;15(8):1294-303. doi: 10.1111/pme.12364. Epub 2014 Feb 15.

31.

A case of Robin sequence, microgastria, radiohumeral synostosis, femoral deficiency, and other unusual findings: a newly recognized syndrome?

Roberts J, Torres-Martinez W, Farrow E, Stevens A, Delk P, White KE, Weaver DD.

Am J Med Genet A. 2014 Feb;164A(2):287-90. doi: 10.1002/ajmg.a.36273. Epub 2013 Dec 5.

PMID:
24311538
32.

Targeted glomerular angiopoietin-1 therapy for early diabetic kidney disease.

Dessapt-Baradez C, Woolf AS, White KE, Pan J, Huang JL, Hayward AA, Price KL, Kolatsi-Joannou M, Locatelli M, Diennet M, Webster Z, Smillie SJ, Nair V, Kretzler M, Cohen CD, Long DA, Gnudi L.

J Am Soc Nephrol. 2014 Jan;25(1):33-42. doi: 10.1681/ASN.2012121218. Epub 2013 Sep 5.

33.

Neonatal iron deficiency causes abnormal phosphate metabolism by elevating FGF23 in normal and ADHR mice.

Clinkenbeard EL, Farrow EG, Summers LJ, Cass TA, Roberts JL, Bayt CA, Lahm T, Albrecht M, Allen MR, Peacock M, White KE.

J Bone Miner Res. 2014 Feb;29(2):361-9. doi: 10.1002/jbmr.2049.

34.

Is blunted cardiovascular reactivity in depression mood-state dependent? A comparison of major depressive disorder remitted depression and healthy controls.

Salomon K, Bylsma LM, White KE, Panaite V, Rottenberg J.

Int J Psychophysiol. 2013 Oct;90(1):50-7. doi: 10.1016/j.ijpsycho.2013.05.018. Epub 2013 Jun 10.

35.

Osteocyte regulation of phosphate homeostasis and bone mineralization underlies the pathophysiology of the heritable disorders of rickets and osteomalacia.

Feng JQ, Clinkenbeard EL, Yuan B, White KE, Drezner MK.

Bone. 2013 Jun;54(2):213-21. doi: 10.1016/j.bone.2013.01.046. Epub 2013 Feb 9. Review.

36.

Circulating αKlotho influences phosphate handling by controlling FGF23 production.

Smith RC, O'Bryan LM, Farrow EG, Summers LJ, Clinkenbeard EL, Roberts JL, Cass TA, Saha J, Broderick C, Ma YL, Zeng QQ, Kharitonenkov A, Wilson JM, Guo Q, Sun H, Allen MR, Burr DB, Breyer MD, White KE.

J Clin Invest. 2012 Dec;122(12):4710-5. doi: 10.1172/JCI64986. Epub 2012 Nov 26.

37.

eNOS deficiency predisposes podocytes to injury in diabetes.

Yuen DA, Stead BE, Zhang Y, White KE, Kabir MG, Thai K, Advani SL, Connelly KA, Takano T, Zhu L, Cox AJ, Kelly DJ, Gibson IW, Takahashi T, Harris RC, Advani A.

J Am Soc Nephrol. 2012 Nov;23(11):1810-23. doi: 10.1681/ASN.2011121170. Epub 2012 Sep 20.

38.

Research into the structure of the kidney glomerulus--making it count.

White KE.

Micron. 2012 Oct;43(10):1001-9. doi: 10.1016/j.micron.2012.04.013. Epub 2012 May 2. Review.

PMID:
22607953
39.

Miscellaneous non-inflammatory musculoskeletal conditions. Hyperphosphatemic familial tumoral calcinosis (FGF23, GALNT3 and αKlotho).

Farrow EG, Imel EA, White KE.

Best Pract Res Clin Rheumatol. 2011 Oct;25(5):735-47. doi: 10.1016/j.berh.2011.10.020. Review.

40.

Leveraging state immunization information systems to measure the effectiveness of rotavirus vaccine.

Cortese MM, Leblanc J, White KE, Jerris RC, Stinchfield P, Preston KL, Meek J, Odofin L, Khizer S, Miller CA, Buttery V, Mijatovic-Rustempasic S, Lewis J, Parashar UD, Immergluck LC.

Pediatrics. 2011 Dec;128(6):e1474-81. doi: 10.1542/peds.2011-1006. Epub 2011 Nov 14.

PMID:
22084328
41.

High hamstring tendinopathy in 3 female long distance runners.

White KE.

J Chiropr Med. 2011 Jun;10(2):93-9. doi: 10.1016/j.jcm.2010.10.005. Epub 2011 Apr 5.

42.

Iron deficiency drives an autosomal dominant hypophosphatemic rickets (ADHR) phenotype in fibroblast growth factor-23 (Fgf23) knock-in mice.

Farrow EG, Yu X, Summers LJ, Davis SI, Fleet JC, Allen MR, Robling AG, Stayrook KR, Jideonwo V, Magers MJ, Garringer HJ, Vidal R, Chan RJ, Goodwin CB, Hui SL, Peacock M, White KE.

Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):E1146-55. doi: 10.1073/pnas.1110905108. Epub 2011 Oct 17.

43.

Educational attainment moderates the effect of a brief diabetes self-care intervention.

Sacco WP, Bykowski CA, Mayhew LL, White KE.

Diabetes Res Clin Pract. 2012 Jan;95(1):62-7. doi: 10.1016/j.diabres.2011.08.027. Epub 2011 Oct 11.

PMID:
21992869
44.

The pathophysiology of early-stage chronic kidney disease-mineral bone disorder (CKD-MBD) and response to phosphate binders in the rat.

Moe SM, Radcliffe JS, White KE, Gattone VH 2nd, Seifert MF, Chen X, Aldridge B, Chen NX.

J Bone Miner Res. 2011 Nov;26(11):2672-81. doi: 10.1002/jbmr.485.

45.

Parathyroid hormone receptor signaling in osteocytes increases the expression of fibroblast growth factor-23 in vitro and in vivo.

Rhee Y, Bivi N, Farrow E, Lezcano V, Plotkin LI, White KE, Bellido T.

Bone. 2011 Oct;49(4):636-43. doi: 10.1016/j.bone.2011.06.025. Epub 2011 Jun 25.

46.

Long-term administration of the histone deacetylase inhibitor vorinostat attenuates renal injury in experimental diabetes through an endothelial nitric oxide synthase-dependent mechanism.

Advani A, Huang Q, Thai K, Advani SL, White KE, Kelly DJ, Yuen DA, Connelly KA, Marsden PA, Gilbert RE.

Am J Pathol. 2011 May;178(5):2205-14. doi: 10.1016/j.ajpath.2011.01.044.

47.

The cardiac (pro)renin receptor is primarily expressed in myocyte transverse tubules and is increased in experimental diabetic cardiomyopathy.

Connelly KA, Advani A, Kim S, Advani SL, Zhang M, White KE, Kim YM, Parker C, Thai K, Krum H, Kelly DJ, Gilbert RE.

J Hypertens. 2011 Jun;29(6):1175-84. doi: 10.1097/HJH.0b013e3283462674.

PMID:
21505358
48.

Mast cells are a source of transforming growth factor β in systemic sclerosis.

Hügle T, Hogan V, White KE, van Laar JM.

Arthritis Rheum. 2011 Mar;63(3):795-9. doi: 10.1002/art.30190.

49.

Up-to-date Haemophilus influenzae type b vaccination coverage during a vaccine shortage.

White KE, Pabst LJ, Cullen KA.

Pediatrics. 2011 Mar;127(3):e707-12. doi: 10.1542/peds.2010-2129. Epub 2011 Feb 21.

PMID:
21339271
50.

Implementation of a guideline for the treatment of pain, sedation, agitation and neuromuscular blockade in the mechanically ventilated adult patient in the emergency department.

White KE, Szumita PM, Gilboy N, Keenan HA, Arbelaez C.

Open Access Emerg Med. 2011 Apr 8;3:21-7. doi: 10.2147/OAEM.S17042. eCollection 2011.

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