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Coupled Electron- and Phase-Transfer Reactions at a Three-Phase Interface.

Terry Weatherly CK, Ren H, Edwards MA, Wang L, White HS.

J Am Chem Soc. 2019 Nov 13;141(45):18091-18098. doi: 10.1021/jacs.9b07283. Epub 2019 Oct 30.


A synthetic chemist's guide to electroanalytical tools for studying reaction mechanisms.

Sandford C, Edwards MA, Klunder KJ, Hickey DP, Li M, Barman K, Sigman MS, White HS, Minteer SD.

Chem Sci. 2019 May 23;10(26):6404-6422. doi: 10.1039/c9sc01545k. eCollection 2019 Jul 14. Review.


Electrochemical Synthesis of Individual Core@Shell and Hollow Ag/Ag2S Nanoparticles.

Robinson DA, White HS.

Nano Lett. 2019 Aug 14;19(8):5612-5619. doi: 10.1021/acs.nanolett.9b02144. Epub 2019 Jul 26.


The pharmacokinetics of oral carbamazepine in rats dosed using an automated drug delivery system.

Hill AC, Rower JE, White HS.

Epilepsia. 2019 Sep;60(9):1829-1837. doi: 10.1111/epi.16293. Epub 2019 Jul 22.


Enhancing Lithium Insertion with Electrostatic Nanoconfinement in a Lithography Patterned Precision Cell.

Li SX, Kim NS, McKelvey K, Liu C, White HS, Rubloff GW, Lee SB, Reed MA.

ACS Nano. 2019 Jul 23;13(7):8481-8489. doi: 10.1021/acsnano.9b04390. Epub 2019 Jul 5.


Music-Enhanced Analgesia and Antiseizure Activities in Animal Models of Pain and Epilepsy: Toward Preclinical Studies Supporting Development of Digital Therapeutics and Their Combinations With Pharmaceutical Drugs.

Metcalf CS, Huntsman M, Garcia G, Kochanski AK, Chikinda M, Watanabe E, Underwood T, Vanegas F, Smith MD, White HS, Bulaj G.

Front Neurol. 2019 Mar 27;10:277. doi: 10.3389/fneur.2019.00277. eCollection 2019.


A summary of data presented at the XIV conference on new antiepileptic drug and devices (EILAT XIV).

Bialer M, Johannessen SI, Koepp MJ, Levy RH, Perucca E, Tomson T, White HS.

Epilepsy Res. 2019 Jul;153:66-67. doi: 10.1016/j.eplepsyres.2019.03.002. Epub 2019 Mar 11.


Electrochemically Driven, Ni-Catalyzed Aryl Amination: Scope, Mechanism, and Applications.

Kawamata Y, Vantourout JC, Hickey DP, Bai P, Chen L, Hou Q, Qiao W, Barman K, Edwards MA, Garrido-Castro AF, deGruyter JN, Nakamura H, Knouse K, Qin C, Clay KJ, Bao D, Li C, Starr JT, Garcia-Irizarry C, Sach N, White HS, Neurock M, Minteer SD, Baran PS.

J Am Chem Soc. 2019 Apr 17;141(15):6392-6402. doi: 10.1021/jacs.9b01886. Epub 2019 Apr 2.


Voltammetric Determination of the Stochastic Formation Rate and Geometry of Individual H2, N2, and O2 Bubble Nuclei.

Edwards MA, White HS, Ren H.

ACS Nano. 2019 Jun 25;13(6):6330-6340. doi: 10.1021/acsnano.9b01015. Epub 2019 Mar 27.


Correction of medication nonadherence results in better seizure outcomes than dose escalation in a novel preclinical epilepsy model of adherence.

Hill AC, Thomson KE, Newell TG, White HS.

Epilepsia. 2019 Mar;60(3):475-484. doi: 10.1111/epi.14655. Epub 2019 Jan 22.


Cannabidiol reduces seizures and associated behavioral comorbidities in a range of animal seizure and epilepsy models.

Patra PH, Barker-Haliski M, White HS, Whalley BJ, Glyn S, Sandhu H, Jones N, Bazelot M, Williams CM, McNeish AJ.

Epilepsia. 2019 Feb;60(2):303-314. doi: 10.1111/epi.14629. Epub 2018 Dec 26.


Brief history of anti-seizure drug development.

Rho JM, White HS.

Epilepsia Open. 2018 Oct 24;3(Suppl Suppl 2):114-119. doi: 10.1002/epi4.12268. eCollection 2018 Dec.


Intravenously Administered Ganaxolone Blocks Diazepam-Resistant Lithium-Pilocarpine-Induced Status Epilepticus in Rats: Comparison with Allopregnanolone.

Saporito MS, Gruner JA, DiCamillo A, Hinchliffe R, Barker-Haliski M, White HS.

J Pharmacol Exp Ther. 2019 Mar;368(3):326-337. doi: 10.1124/jpet.118.252155. Epub 2018 Dec 14.


Progress report on new antiepileptic drugs: A summary of the Fourteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIV). I. Drugs in preclinical and early clinical development.

Bialer M, Johannessen SI, Koepp MJ, Levy RH, Perucca E, Tomson T, White HS.

Epilepsia. 2018 Oct;59(10):1811-1841. doi: 10.1111/epi.14557.


Progress report on new antiepileptic drugs: A summary of the Fourteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIV). II. Drugs in more advanced clinical development.

Bialer M, Johannessen SI, Koepp MJ, Levy RH, Perucca E, Tomson T, White HS.

Epilepsia. 2018 Oct;59(10):1842-1866. doi: 10.1111/epi.14555. Erratum in: Epilepsia. 2019 Jan;60(1):187.


Recurrent epileptiform discharges in the medial entorhinal cortex of kainate-treated rats are differentially sensitive to antiseizure drugs.

West PJ, Saunders GW, Billingsley P, Smith MD, White HS, Metcalf CS, Wilcox KS.

Epilepsia. 2018 Nov;59(11):2035-2048. doi: 10.1111/epi.14563. Epub 2018 Oct 17.


γ-Hemolysin Nanopore Is Sensitive to Guanine-to-Inosine Substitutions in Double-Stranded DNA at the Single-Molecule Level.

Tan CS, Fleming AM, Ren H, Burrows CJ, White HS.

J Am Chem Soc. 2018 Oct 31;140(43):14224-14234. doi: 10.1021/jacs.8b08153. Epub 2018 Oct 16.


Nanoscale electrochemical kinetics & dynamics: the challenges and opportunities of single-entity measurements.

Edwards MA, Robinson DA, Ren H, Cheyne CG, Tan CS, White HS.

Faraday Discuss. 2018 Oct 1;210(0):9-28. doi: 10.1039/c8fd00134k.


Single Ag nanoparticle collisions within a dual-electrode micro-gap cell.

McKelvey K, Robinson DA, Vitti NJ, Edwards MA, White HS.

Faraday Discuss. 2018 Oct 1;210(0):189-200. doi: 10.1039/c8fd00014j.


The Nucleation Rate of Single O2 Nanobubbles at Pt Nanoelectrodes.

Soto ÁM, German SR, Ren H, van der Meer D, Lohse D, Edwards MA, White HS.

Langmuir. 2018 Jun 26;34(25):7309-7318. doi: 10.1021/acs.langmuir.8b01372. Epub 2018 Jun 13.


Lamotrigine-resistant corneal-kindled mice: A model of pharmacoresistant partial epilepsy for moderate-throughput drug discovery.

Koneval Z, Knox KM, White HS, Barker-Haliski M.

Epilepsia. 2018 Jun;59(6):1245-1256. doi: 10.1111/epi.14190. Epub 2018 May 11.


Single-Molecule Titration in a Protein Nanoreactor Reveals the Protonation/Deprotonation Mechanism of a C:C Mismatch in DNA.

Ren H, Cheyne CG, Fleming AM, Burrows CJ, White HS.

J Am Chem Soc. 2018 Apr 18;140(15):5153-5160. doi: 10.1021/jacs.8b00593. Epub 2018 Apr 3.


Nanopore Opening at Flat and Nanotip Conical Electrodes during Vesicle Impact Electrochemical Cytometry.

Li X, Ren L, Dunevall J, Ye D, White HS, Edwards MA, Ewing AG.

ACS Nano. 2018 Mar 27;12(3):3010-3019. doi: 10.1021/acsnano.8b00781. Epub 2018 Mar 16.


Nanopore Analysis of the 5-Guanidinohydantoin to Iminoallantoin Isomerization in Duplex DNA.

Zeng T, Fleming AM, Ding Y, Ren H, White HS, Burrows CJ.

J Org Chem. 2018 Apr 6;83(7):3973-3978. doi: 10.1021/acs.joc.8b00317. Epub 2018 Mar 8.


Critical Nuclei Size, Rate, and Activation Energy of H2 Gas Nucleation.

German SR, Edwards MA, Ren H, White HS.

J Am Chem Soc. 2018 Mar 21;140(11):4047-4053. doi: 10.1021/jacs.7b13457. Epub 2018 Mar 9.


Potent and selective pharmacodynamic synergy between the metabotropic glutamate receptor subtype 2-positive allosteric modulator JNJ-46356479 and levetiracetam in the mouse 6-Hz (44-mA) model.

Metcalf CS, Klein BD, Smith MD, Ceusters M, Lavreysen H, Pype S, Van Osselaer N, Twyman R, White HS.

Epilepsia. 2018 Mar;59(3):724-735. doi: 10.1111/epi.14005. Epub 2018 Jan 23.


Selective increase in CO2 electroreduction activity at grain-boundary surface terminations.

Mariano RG, McKelvey K, White HS, Kanan MW.

Science. 2017 Dec 1;358(6367):1187-1192. doi: 10.1126/science.aao3691.


Collision Dynamics during the Electrooxidation of Individual Silver Nanoparticles.

Robinson DA, Liu Y, Edwards MA, Vitti NJ, Oja SM, Zhang B, White HS.

J Am Chem Soc. 2017 Nov 22;139(46):16923-16931. doi: 10.1021/jacs.7b09842. Epub 2017 Nov 9.


Three-Dimensional Super-resolution Imaging of Single Nanoparticles Delivered by Pipettes.

Yu Y, Sundaresan V, Bandyopadhyay S, Zhang Y, Edwards MA, McKelvey K, White HS, Willets KA.

ACS Nano. 2017 Oct 24;11(10):10529-10538. doi: 10.1021/acsnano.7b05902. Epub 2017 Oct 5.


Neuroinflammation in epileptogenesis: Insights and translational perspectives from new models of epilepsy.

Barker-Haliski ML, Löscher W, White HS, Galanopoulou AS.

Epilepsia. 2017 Jul;58 Suppl 3:39-47. doi: 10.1111/epi.13785.


Corneal kindled C57BL/6 mice exhibit saturated dentate gyrus long-term potentiation and associated memory deficits in the absence of overt neuron loss.

Remigio GJ, Loewen JL, Heuston S, Helgeson C, White HS, Wilcox KS, West PJ.

Neurobiol Dis. 2017 Sep;105:221-234. doi: 10.1016/j.nbd.2017.06.006. Epub 2017 Jun 15.


Electrochemical Generation of Individual O2 Nanobubbles via H2O2 Oxidation.

Ren H, German SR, Edwards MA, Chen Q, White HS.

J Phys Chem Lett. 2017 Jun 1;8(11):2450-2454. doi: 10.1021/acs.jpclett.7b00882. Epub 2017 May 19.


Hippocampal TNFα Signaling Contributes to Seizure Generation in an Infection-Induced Mouse Model of Limbic Epilepsy.

Patel DC, Wallis G, Dahle EJ, McElroy PB, Thomson KE, Tesi RJ, Szymkowski DE, West PJ, Smeal RM, Patel M, Fujinami RS, White HS, Wilcox KS.

eNeuro. 2017 May 9;4(2). pii: ENEURO.0105-17.2017. doi: 10.1523/ENEURO.0105-17.2017. eCollection 2017 Mar-Apr.


Development and pharmacologic characterization of the rat 6 Hz model of partial seizures.

Metcalf CS, West PJ, Thomson KE, Edwards SF, Smith MD, White HS, Wilcox KS.

Epilepsia. 2017 Jun;58(6):1073-1084. doi: 10.1111/epi.13764. Epub 2017 Apr 27.


The novel anticonvulsant neuropeptide and galanin analogue, NAX-5055, does not alter energy and amino acid metabolism in cultured brain cells.

Aldana BI, Waagepetersen HS, Schousboe A, White HS, Bulaj G, Walls AB.

J Neurosci Res. 2017 Nov;95(11):2286-2296. doi: 10.1002/jnr.24057. Epub 2017 Apr 11.


Interrogation of Base Pairing of the Spiroiminodihydantoin Diastereomers Using the α-Hemolysin Latch.

Zeng T, Fleming AM, Ding Y, White HS, Burrows CJ.

Biochemistry. 2017 Mar 21;56(11):1596-1603. doi: 10.1021/acs.biochem.6b01175. Epub 2017 Mar 9.


CDK4/6 Therapeutic Intervention and Viable Alternative to Taxanes in CRPC.

Stice JP, Wardell SE, Norris JD, Yllanes AP, Alley HM, Haney VO, White HS, Safi R, Winter PS, Cocce KJ, Kishton RJ, Lawrence SA, Strum JC, McDonnell DP.

Mol Cancer Res. 2017 Jun;15(6):660-669. doi: 10.1158/1541-7786.MCR-17-0028. Epub 2017 Feb 16.


Single Nanochannel Platform for Detecting Chiral Drugs.

Boussouar I, Chen Q, Chen X, Zhang Y, Zhang F, Tian D, White HS, Li H.

Anal Chem. 2017 Jan 17;89(2):1110-1116. doi: 10.1021/acs.analchem.6b02682. Epub 2016 Dec 22.


Efficacy of mGlu2 -positive allosteric modulators alone and in combination with levetiracetam in the mouse 6 Hz model of psychomotor seizures.

Metcalf CS, Klein BD, Smith MD, Pruess T, Ceusters M, Lavreysen H, Pype S, Van Osselaer N, Twyman R, White HS.

Epilepsia. 2017 Mar;58(3):484-493. doi: 10.1111/epi.13659. Epub 2017 Feb 6.


The Dynamic Steady State of an Electrochemically Generated Nanobubble.

Liu Y, Edwards MA, German SR, Chen Q, White HS.

Langmuir. 2017 Feb 28;33(8):1845-1853. doi: 10.1021/acs.langmuir.6b04607. Epub 2017 Feb 13.


Dynamics of a DNA Mismatch Site Held in Confinement Discriminate Epigenetic Modifications of Cytosine.

Johnson RP, Fleming AM, Perera RT, Burrows CJ, White HS.

J Am Chem Soc. 2017 Feb 22;139(7):2750-2756. doi: 10.1021/jacs.6b12284. Epub 2017 Feb 13.


Seizure detection and neuromodulation: A summary of data presented at the XIII conference on new antiepileptic drug and devices (EILAT XIII).

Bialer M, Johannessen SI, Levy RH, Perucca E, Tomson T, White HS, Koepp MJ.

Epilepsy Res. 2017 Feb;130:27-36. doi: 10.1016/j.eplepsyres.2017.01.004. Epub 2017 Jan 16.


Progress report on new antiepileptic drugs: A summary of the Thirteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIII).

Bialer M, Johannessen SI, Levy RH, Perucca E, Tomson T, White HS.

Epilepsia. 2017 Feb;58(2):181-221. doi: 10.1111/epi.13634. Epub 2017 Jan 23. Review.


Preclinical evaluation of intravenous NAX 810-2, a novel GalR2-preferring analog, for anticonvulsant efficacy and pharmacokinetics.

Metcalf CS, Klein BD, McDougle DR, Zhang L, Kaufmann D, Bulaj G, White HS.

Epilepsia. 2017 Feb;58(2):239-246. doi: 10.1111/epi.13647. Epub 2017 Jan 18.


Kinetics of T3-DNA Ligase-Catalyzed Phosphodiester Bond Formation Measured Using the α-Hemolysin Nanopore.

Tan CS, Riedl J, Fleming AM, Burrows CJ, White HS.

ACS Nano. 2016 Dec 27;10(12):11127-11135. doi: 10.1021/acsnano.6b05995. Epub 2016 Dec 2.


Observation of Multipeak Collision Behavior during the Electro-Oxidation of Single Ag Nanoparticles.

Oja SM, Robinson DA, Vitti NJ, Edwards MA, Liu Y, White HS, Zhang B.

J Am Chem Soc. 2017 Jan 18;139(2):708-718. doi: 10.1021/jacs.6b11143. Epub 2016 Dec 22.


Fabrication, Testing, and Simulation of All-Solid-State Three-Dimensional Li-Ion Batteries.

Talin AA, Ruzmetov D, Kolmakov A, McKelvey K, Ware N, El Gabaly F, Dunn B, White HS.

ACS Appl Mater Interfaces. 2016 Nov 30;8(47):32385-32391. Epub 2016 Nov 18.


sec-Butylpropylacetamide (SPD), a new amide derivative of valproic acid for the treatment of neuropathic and inflammatory pain.

Kaufmann D, West PJ, Smith MD, Yagen B, Bialer M, Devor M, White HS, Brennan KC.

Pharmacol Res. 2017 Mar;117:129-139. doi: 10.1016/j.phrs.2016.11.030. Epub 2016 Nov 24.


Deconstructing tolerance with clobazam: Post hoc analyses from an open-label extension study.

Gidal BE, Wechsler RT, Sankar R, Montouris GD, White HS, Cloyd JC, Kane MC, Peng G, Tworek DM, Shen V, Isojarvi J.

Neurology. 2016 Oct 25;87(17):1806-1812. Epub 2016 Sep 28.


Acute treatment with minocycline, but not valproic acid, improves long-term behavioral outcomes in the Theiler's virus model of temporal lobe epilepsy.

Barker-Haliski ML, Heck TD, Dahle EJ, Vanegas F, Pruess TH, Wilcox KS, White HS.

Epilepsia. 2016 Dec;57(12):1958-1967. doi: 10.1111/epi.13577. Epub 2016 Oct 14.

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