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Items: 1 to 50 of 201

1.

Laser Sintering of Liquid Metal Nanoparticles for Scalable Manufacturing of Soft and Flexible Electronics.

Liu S, Yuen MC, White EL, Boley JW, Deng B, Cheng GJ, Kramer-Bottiglio R.

ACS Appl Mater Interfaces. 2018 Aug 22;10(33):28232-28241. doi: 10.1021/acsami.8b08722. Epub 2018 Aug 9.

PMID:
30045618
2.

Reducing Actuator Requirements in Continuum Robots Through Optimized Cable Routing.

Case JC, White EL, SunSpiral V, Kramer-Bottiglio R.

Soft Robot. 2018 Feb;5(1):109-118. doi: 10.1089/soro.2017.0030. Epub 2017 Oct 26.

PMID:
29412083
3.

Implementation of Glycan Remodeling to Plant-Made Therapeutic Antibodies.

Bennett LD, Yang Q, Berquist BR, Giddens JP, Ren Z, Kommineni V, Murray RP, White EL, Holtz BR, Wang LX, Marcel S.

Int J Mol Sci. 2018 Jan 31;19(2). pii: E421. doi: 10.3390/ijms19020421.

4.

A Soft Parallel Kinematic Mechanism.

White EL, Case JC, Kramer-Bottiglio R.

Soft Robot. 2018 Feb;5(1):36-53. doi: 10.1089/soro.2017.0033. Epub 2017 Dec 18.

PMID:
29252099
5.

Effects of an unusual poison identify a lifespan role for Topoisomerase 2 in Saccharomyces cerevisiae.

Tombline G, Millen JI, Polevoda B, Rapaport M, Baxter B, Van Meter M, Gilbertson M, Madrey J, Piazza GA, Rasmussen L, Wennerberg K, White EL, Nitiss JL, Goldfarb DS.

Aging (Albany NY). 2017 Jan 5;9(1):68-97. doi: 10.18632/aging.101114.

6.

Discovery of Clinically Approved Agents That Promote Suppression of Cystic Fibrosis Transmembrane Conductance Regulator Nonsense Mutations.

Mutyam V, Du M, Xue X, Keeling KM, White EL, Bostwick JR, Rasmussen L, Liu B, Mazur M, Hong JS, Falk Libby E, Liang F, Shang H, Mense M, Suto MJ, Bedwell DM, Rowe SM.

Am J Respir Crit Care Med. 2016 Nov 1;194(9):1092-1103.

7.

Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.

Chung WJ, Goeckeler-Fried JL, Havasi V, Chiang A, Rowe SM, Plyler ZE, Hong JS, Mazur M, Piazza GA, Keeton AB, White EL, Rasmussen L, Weissman AM, Denny RA, Brodsky JL, Sorscher EJ.

PLoS One. 2016 Oct 12;11(10):e0163615. doi: 10.1371/journal.pone.0163615. eCollection 2016.

8.

Identification of Small Molecule Inhibitors of Human Cytochrome c Oxidase That Target Chemoresistant Glioma Cells.

Oliva CR, Markert T, Ross LJ, White EL, Rasmussen L, Zhang W, Everts M, Moellering DR, Bailey SM, Suto MJ, Griguer CE.

J Biol Chem. 2016 Nov 11;291(46):24188-24199. Epub 2016 Sep 27.

9.

Mycobacterium tuberculosis High-Throughput Screening.

White EL, Tower NA, Rasmussen L.

Methods Mol Biol. 2016;1439:181-95. doi: 10.1007/978-1-4939-3673-1_12.

PMID:
27316996
10.

Hybrid Self-Assembly during Evaporation Enables Drop-on-Demand Thin Film Devices.

Boley JW, Hyun SH, White EL, Thompson DH, Kramer RK.

ACS Appl Mater Interfaces. 2016 Dec 21;8(50):34171-34178. doi: 10.1021/acsami.5b12687. Epub 2016 Apr 1.

PMID:
27008567
11.

Discovery of a novel inhibitor of kinesin-like protein KIFC1.

Zhang W, Zhai L, Wang Y, Boohaker RJ, Lu W, Gupta VV, Padmalayam I, Bostwick RJ, White EL, Ross LJ, Maddry J, Ananthan S, Augelli-Szafran CE, Suto MJ, Xu B, Li R, Li Y.

Biochem J. 2016 Apr 15;473(8):1027-35. doi: 10.1042/BJ20150992. Epub 2016 Feb 4.

12.

Acoustic Droplet Ejection Applications for High-Throughput Screening of Infectious Agents.

Rasmussen L, White EL, Bostwick JR.

J Lab Autom. 2016 Feb;21(1):188-97. doi: 10.1177/2211068215620345. Epub 2015 Dec 9.

PMID:
26663786
13.

Acoustic Droplet Ejection Technology and Its Application in High-Throughput RNA Interference Screening.

Nebane NM, Coric T, McKellip S, Woods L, Sosa M, Rasmussen L, Bjornsti MA, White EL.

J Lab Autom. 2016 Feb;21(1):198-203. doi: 10.1177/2211068215620346. Epub 2015 Dec 9.

14.

Commercial-scale biotherapeutics manufacturing facility for plant-made pharmaceuticals.

Holtz BR, Berquist BR, Bennett LD, Kommineni VJ, Munigunti RK, White EL, Wilkerson DC, Wong KY, Ly LH, Marcel S.

Plant Biotechnol J. 2015 Oct;13(8):1180-90. doi: 10.1111/pbi.12469. Review.

15.

Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes.

Schreiber SL, Kotz JD, Li M, Aubé J, Austin CP, Reed JC, Rosen H, White EL, Sklar LA, Lindsley CW, Alexander BR, Bittker JA, Clemons PA, de Souza A, Foley MA, Palmer M, Shamji AF, Wawer MJ, McManus O, Wu M, Zou B, Yu H, Golden JE, Schoenen FJ, Simeonov A, Jadhav A, Jackson MR, Pinkerton AB, Chung TD, Griffin PR, Cravatt BF, Hodder PS, Roush WR, Roberts E, Chung DH, Jonsson CB, Noah JW, Severson WE, Ananthan S, Edwards B, Oprea TI, Conn PJ, Hopkins CR, Wood MR, Stauffer SR, Emmitte KA; NIH Molecular Libraries Project Team.

Cell. 2015 Jun 4;161(6):1252-65. doi: 10.1016/j.cell.2015.05.023. Review.

16.

Adult activity and temperature preference drives region-wide damselfly (Zygoptera) distributions under a warming climate.

Corser JD, White EL, Schlesinger MD.

Biol Lett. 2015 Apr;11(4):20150001. doi: 10.1098/rsbl.2015.0001.

17.

Identification of a chemically validated target in replicating and non-replicating Mycobacterium tuberculosis with the aid of a small molecule probe.

Nag PP, Grant SS, Lewis TA, Gordon K, Kawate T, Fitzgerald M, Nietupski R, Gomez J, White EL, Maddox C, Nebane NM, Tower NA, McKellip S, Sosa M, Rasmussen L, Johnston S, Bittker JA, Dandapani S, Perez J, Munoz B, Palmer M, Schreiber SL, Hung DT.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2014 Apr 15 [updated 2015 Jan 16].

18.

Mechanically sintered gallium-indium nanoparticles.

Boley JW, White EL, Kramer RK.

Adv Mater. 2015 Apr 8;27(14):2355-60. doi: 10.1002/adma.201404790. Epub 2015 Feb 27.

PMID:
25728533
19.

Identification of a novel HIV-1 inhibitor targeting Vif-dependent degradation of human APOBEC3G protein.

Pery E, Sheehy A, Nebane NM, Brazier AJ, Misra V, Rajendran KS, Buhrlage SJ, Mankowski MK, Rasmussen L, White EL, Ptak RG, Gabuzda D.

J Biol Chem. 2015 Apr 17;290(16):10504-17. doi: 10.1074/jbc.M114.626903. Epub 2015 Feb 27.

20.

Adapting high-throughput screening methods and assays for biocontainment laboratories.

Rasmussen L, Tigabu B, White EL, Bostwick R, Tower N, Bukreyev A, Rockx B, LeDuc JW, Noah JW.

Assay Drug Dev Technol. 2015 Jan-Feb;13(1):44-54. doi: 10.1089/adt.2014.617. Review.

21.

Inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase.

Schoenen FJ, Whipple D, Baillargeon P, Brown CL, Chase P, Ferguson J, Fernandez-Vega V, Hodder P, Mathew R, Neuenswander B, Porubsky P, Rogers S, Skinner-Adams T, Sosa M, Spicer T, To J, Tower NA, Trenholme KR, Wang J, Weiner WS, Aubé J, Rosen H, White EL, Gardiner DL, Dalton JP.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2013 Dec 12 [updated 2014 Sep 18].

22.

Optimization of potent and selective quinazolinediones: inhibitors of respiratory syncytial virus that block RNA-dependent RNA-polymerase complex activity.

Matharu DS, Flaherty DP, Simpson DS, Schroeder CE, Chung D, Yan D, Noah JW, Jonsson CB, White EL, Aubé J, Plemper RK, Severson WE, Golden JE.

J Med Chem. 2014 Dec 26;57(24):10314-28. doi: 10.1021/jm500902x. Epub 2014 Dec 4.

23.

Development of (E)-2-((1,4-dimethylpiperazin-2-ylidene)amino)-5-nitro-N-phenylbenzamide, ML336: Novel 2-amidinophenylbenzamides as potent inhibitors of venezuelan equine encephalitis virus.

Schroeder CE, Yao T, Sotsky J, Smith RA, Roy S, Chu YK, Guo H, Tower NA, Noah JW, McKellip S, Sosa M, Rasmussen L, Smith LH, White EL, Aubé J, Jonsson CB, Chung D, Golden JE.

J Med Chem. 2014 Oct 23;57(20):8608-21. doi: 10.1021/jm501203v. Epub 2014 Oct 7.

24.

Unique functional and structural properties of the LRRK2 protein ATP-binding pocket.

Liu Z, Galemmo RA Jr, Fraser KB, Moehle MS, Sen S, Volpicelli-Daley LA, DeLucas LJ, Ross LJ, Valiyaveettil J, Moukha-Chafiq O, Pathak AK, Ananthan S, Kezar H, White EL, Gupta V, Maddry JA, Suto MJ, West AB.

J Biol Chem. 2014 Nov 21;289(47):32937-51. doi: 10.1074/jbc.M114.602318. Epub 2014 Sep 16.

25.

Inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase.

Schoenen FJ, Weiner WS, Baillargeon P, Brown CL, Chase P, Ferguson J, Fernandez-Vega V, Ghosh P, Hodder P, Krise JP, Matharu DS, Neuenswander B, Porubsky P, Rogers S, Skinner-Adams T, Sosa M, Spicer T, To J, Tower NA, Trenholme KR, Wang J, Whipple D, Aubé J, Rosen H, White EL, Dalton JP, Gardiner DL.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2013 Apr 12 [updated 2014 Sep 18].

26.

AlphaScreen HTS and live-cell bioluminescence resonance energy transfer (BRET) assays for identification of Tau-Fyn SH3 interaction inhibitors for Alzheimer disease.

Cochran JN, Diggs PV, Nebane NM, Rasmussen L, White EL, Bostwick R, Maddry JA, Suto MJ, Roberson ED.

J Biomol Screen. 2014 Dec;19(10):1338-49. doi: 10.1177/1087057114547232. Epub 2014 Aug 25.

27.

Lifting the mask: identification of new small molecule inhibitors of uropathogenic Escherichia coli group 2 capsule biogenesis.

Goller CC, Arshad M, Noah JW, Ananthan S, Evans CW, Nebane NM, Rasmussen L, Sosa M, Tower NA, White EL, Neuenswander B, Porubsky P, Maki BE, Rogers SA, Schoenen F, Seed PC.

PLoS One. 2014 Jul 1;9(7):e96054. doi: 10.1371/journal.pone.0096054. eCollection 2014.

28.

Discovery of a novel compound with anti-venezuelan equine encephalitis virus activity that targets the nonstructural protein 2.

Chung DH, Jonsson CB, Tower NA, Chu YK, Sahin E, Golden JE, Noah JW, Schroeder CE, Sotsky JB, Sosa MI, Cramer DE, McKellip SN, Rasmussen L, White EL, Schmaljohn CS, Julander JG, Smith JM, Filone CM, Connor JH, Sakurai Y, Davey RA.

PLoS Pathog. 2014 Jun 26;10(6):e1004213. doi: 10.1371/journal.ppat.1004213. eCollection 2014 Jun.

29.

A BSL-4 high-throughput screen identifies sulfonamide inhibitors of Nipah virus.

Tigabu B, Rasmussen L, White EL, Tower N, Saeed M, Bukreyev A, Rockx B, LeDuc JW, Noah JW.

Assay Drug Dev Technol. 2014 Apr;12(3):155-61. doi: 10.1089/adt.2013.567.

30.

ML336: Development of Quinazolinone-Based Inhibitors Against Venezuelan Equine Encephalitis Virus (VEEV).

Chung D, Schroeder CE, Sotsky J, Yao T, Roy S, Smith RA, Tower NA, Noah JW, McKellip S, Sosa M, Rasmussen L, White EL, Aubé J, Golden JE.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2012 Dec 17 [updated 2013 Nov 7].

31.

Elucidation of the physiology of non-replicating, drug tolerant Mycobacterium tuberculosis with the aid of the small molecule probe ML338.

Nag PP, Grant SS, Lewis TA, Gordon K, Kawate T, Iwase N, White EL, Maddox C, Nebane NM, Tower NA, McKellip S, Sosa MI, Rasmussen L, Mosher CM, Anthoine T, Johnston S, Dandapani S, Perez J, Munoz B, Palmer M, Schreiber SL, Hung DT.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2012 Dec 17 [updated 2013 Sep 16].

32.

A highly specific cell-based high-throughput screening assay for ligands of cyclic adenosine monophosphate receptor protein in gram-negative bacteria.

Wang H, Silva AJ, Rasmussen L, White EL, Benitez JA.

Assay Drug Dev Technol. 2013 Jul;11(6):382-7. doi: 10.1089/adt.2013.514. Epub 2013 Aug 1.

33.

N-(pyridin-4-yl)benzo[d]thiazole-6-carboxamide inhibits E. coli UT189 bacterial capsule biogenesis.

Noah JW, Ananthan S, Evans CW, Nebane NM, Rasmussen L, Sosa M, Tower NA, White EL, Seed P, Goller C, Arshad M, Datta A, Neuenswander B, Porubsky P, Maki BE, Liu C, Rogers SA, Schoenen F, Aubé J.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2012 Dec 17 [updated 2013 Apr 5].

34.

3-(2,6-difluorobenzamido)-5-(4-ethoxyphenyl) thiophene-2-carboxylic acid inhibits E.coli UT189 bacterial capsule biogenesis.

Noah JW, Ananthan S, Evans CW, Nebane NM, Rasmussen L, Sosa M, Tower NA, White EL, Seed P, Goller C, Datta A, Neuenswander B, Porubsky P, Maki BE, Rogers SA, Schoenen F, Aubé J.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2012 Apr 16 [updated 2013 Mar 14].

35.

Discovery and Development of Highly Potent Inhibitors of Mycobacterium tuberculosis Growth In Vitro.

White EL, Maddox C, Nebane NM, Tower NA, McKellip S, Manuvakhova A, Reddy L, Sosa M, Rasmussen L, Whig K, Ananthan S, Lun S, Bishai W, Weiner WS, Schoenen F, Dutta A, Aubé J.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2011 Apr 15 [updated 2013 Mar 7].

36.

A Cell Based HTS Approach for the Discovery of New Inhibitors of RSV.

Noah JW, Severson W, Chung DH, Moore B, Jia F, Xu X, Maddox C, Rasmussen L, Sosa MI, Tower NA, Ananthan S, White EL, Jonsson C, Matharu DS, Golden JE, Prisinzano TE, Aubé J.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2011 Apr 15 [updated 2013 Feb 28].

37.

Identification of a Series of Quinazolinediones as Potent, Selective, Post-Entry Inhibitors of Human Respiratory Syncytial Virus (hRSV) via a Cell-Based High Throughput Screen and Chemical Optimization.

Noah JW, Severson WE, Chung DH, Moore B, Jia F, Xu X, Maddox C, Rasmussen L, Sosa MI, Tower NA, Ananthan S, Evans CW, White EL, Jonsson C, Matharu DS, Flaherty DP, Simpson DS, Golden JE, Aubé J.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2011 Dec 16 [updated 2013 Feb 28].

38.

High-throughput RNA interference screening: tricks of the trade.

Nebane NM, Coric T, Whig K, McKellip S, Woods L, Sosa M, Sheppard R, Rasmussen L, Bjornsti MA, White EL.

J Lab Autom. 2013 Aug;18(4):334-9. doi: 10.1177/2211068213486786. Epub 2013 Apr 24.

39.

A cell based high-throughput screening approach for the discovery of new inhibitors of respiratory syncytial virus.

Chung DH, Moore BP, Matharu DS, Golden JE, Maddox C, Rasmussen L, Sosa MI, Ananthan S, White EL, Jia F, Jonsson CB, Severson WE.

Virol J. 2013 Jan 10;10:19. doi: 10.1186/1743-422X-10-19.

40.

(S)-N-(2,5-Dimethylphenyl)-1-(quinoline-8-ylsulfonyl)pyrrolidine-2-carboxamide as a small molecule inhibitor probe for the study of respiratory syncytial virus infection.

Moore BP, Chung DH, Matharu DS, Golden JE, Maddox C, Rasmussen L, Noah JW, Sosa MI, Ananthan S, Tower NA, White EL, Jia F, Prisinzano TE, Aubé J, Jonsson CB, Severson WE.

J Med Chem. 2012 Oct 25;55(20):8582-7. doi: 10.1021/jm300612z. Epub 2012 Oct 16.

41.

Discovery of putative salivary biomarkers for Sjögren's syndrome using high resolution mass spectrometry and bioinformatics.

Zoukhri D, Rawe I, Singh M, Brown A, Kublin CL, Dawson K, Haddon WF, White EL, Hanley KM, Tusé D, Malyj W, Papas A.

J Oral Sci. 2012 Mar;54(1):61-70.

42.

Screening methods for influenza antiviral drug discovery.

Atkins C, Evans CW, White EL, Noah JW.

Expert Opin Drug Discov. 2012 May;7(5):429-38. doi: 10.1517/17460441.2012.674510. Epub 2012 Mar 22. Review.

PMID:
22435452
43.

The NIH's role in accelerating translational sciences.

Reed JC, White EL, Aubé J, Lindsley C, Li M, Sklar L, Schreiber S.

Nat Biotechnol. 2012 Jan 9;30(1):16-9. doi: 10.1038/nbt.2087. No abstract available.

PMID:
22231085
44.

Primary and secondary drug screening assays for Friedreich ataxia.

Cotticelli MG, Rasmussen L, Kushner NL, McKellip S, Sosa MI, Manouvakhova A, Feng S, White EL, Maddry JA, Heemskerk J, Oldt RJ, Surrey LF, Ochs R, Wilson RB.

J Biomol Screen. 2012 Mar;17(3):303-13. doi: 10.1177/1087057111427949. Epub 2011 Nov 15.

PMID:
22086726
45.

Novel pyridopyrazine and pyrimidothiazine derivatives as FtsZ inhibitors.

Mathew B, Srivastava S, Ross LJ, Suling WJ, White EL, Woolhiser LK, Lenaerts AJ, Reynolds RC.

Bioorg Med Chem. 2011 Dec 1;19(23):7120-8. doi: 10.1016/j.bmc.2011.09.062. Epub 2011 Oct 5.

46.

High-throughput screening identifies a bisphenol inhibitor of SV40 large T antigen ATPase activity.

Seguin SP, Evans CW, Nebane-Akah M, McKellip S, Ananthan S, Tower NA, Sosa M, Rasmussen L, White EL, Maki BE, Matharu DS, Golden JE, Aubé J, Brodsky JL, Noah JW.

J Biomol Screen. 2012 Feb;17(2):194-203. doi: 10.1177/1087057111421630. Epub 2011 Sep 23.

47.

A high-throughput screening assay for inhibitors of bacterial motility identifies a novel inhibitor of the Na+-driven flagellar motor and virulence gene expression in Vibrio cholerae.

Rasmussen L, White EL, Pathak A, Ayala JC, Wang H, Wu JH, Benitez JA, Silva AJ.

Antimicrob Agents Chemother. 2011 Sep;55(9):4134-43. doi: 10.1128/AAC.00482-11. Epub 2011 Jun 27.

48.

High throughput screening of a library based on kinase inhibitor scaffolds against Mycobacterium tuberculosis H37Rv.

Reynolds RC, Ananthan S, Faaleolea E, Hobrath JV, Kwong CD, Maddox C, Rasmussen L, Sosa MI, Thammasuvimol E, White EL, Zhang W, Secrist JA 3rd.

Tuberculosis (Edinb). 2012 Jan;92(1):72-83. doi: 10.1016/j.tube.2011.05.005. Epub 2011 Jun 25.

49.

NIH: translation centre bridges a gap.

Reed JC, White EL.

Nature. 2011 Jun 8;474(7350):161. doi: 10.1038/474161b. No abstract available.

PMID:
21654789
50.

A Cell Based Assay for the Identification of Lead Compounds with Anti-Viral Activity Against West Nile Virus.

Chung DH, Ardecky R, Ganji SR, Cosford NDP, Jonsson CB, Moore BP, Jia F, Maddox C, McKellip SN, White EL, Ananthan S, Feng S, Rasmussen L, Su Y, Chung TDY, Dad S, Tower NA, Heil M.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2010 Feb 27 [updated 2010 Oct 4].

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