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Items: 1 to 50 of 136

1.

Structure-Based Design of Selective, Covalent G Protein-Coupled Receptor Kinase 5 Inhibitors.

Rowlands RA, Cato MC, Waldschmidt HV, Bouley RA, Chen Q, Avramova L, Larsen SD, Tesmer JJG, White AD.

ACS Med Chem Lett. 2019 Nov 12;10(12):1628-1634. doi: 10.1021/acsmedchemlett.9b00365. eCollection 2019 Dec 12.

PMID:
31857838
2.

PTH/PTHrP Receptor Signaling, Allostery, and Structures.

Sutkeviciute I, Clark LJ, White AD, Gardella TJ, Vilardaga JP.

Trends Endocrinol Metab. 2019 Nov;30(11):860-874. doi: 10.1016/j.tem.2019.07.011. Review.

PMID:
31699241
3.

Use of Backbone Modification To Enlarge the Spatiotemporal Diversity of Parathyroid Hormone Receptor-1 Signaling via Biased Agonism.

Liu S, Jean-Alphonse FG, White AD, Wootten D, Sexton PM, Gardella TJ, Vilardaga JP, Gellman SH.

J Am Chem Soc. 2019 Sep 18;141(37):14486-14490. doi: 10.1021/jacs.9b04179. Epub 2019 Sep 9.

PMID:
31496241
4.

The Use of Closure Devices for Aortic Stent-Graft Insertion: Outcomes Following a Paradigm Shift to Percutaneous Access in a Tertiary Vascular Center.

White AD, Hazar C, Jarosz D, Walker P, Shaw D, Tingerides C.

Vasc Endovascular Surg. 2019 Oct;53(7):536-540. doi: 10.1177/1538574419858829. Epub 2019 Jun 24.

PMID:
31234730
5.

Structure and dynamics of the active human parathyroid hormone receptor-1.

Zhao LH, Ma S, Sutkeviciute I, Shen DD, Zhou XE, de Waal PW, Li CY, Kang Y, Clark LJ, Jean-Alphonse FG, White AD, Yang D, Dai A, Cai X, Chen J, Li C, Jiang Y, Watanabe T, Gardella TJ, Melcher K, Wang MW, Vilardaga JP, Xu HE, Zhang Y.

Science. 2019 Apr 12;364(6436):148-153. doi: 10.1126/science.aav7942.

6.

Author Correction: The influence of haemoglobin and iron on in vitro mycobacterial growth inhibition assays.

Tanner R, O'Shea MK, White AD, Müller J, Harrington-Kandt R, Matsumiya M, Dennis MJ, Parizotto EA, Harris S, Stylianou E, Naranbhai V, Bettencourt P, Drakesmith H, Sharpe S, Fletcher HA, McShane H.

Sci Rep. 2019 Apr 3;9(1):5596. doi: 10.1038/s41598-019-41387-8.

7.

Differences in monocyte: lymphocyte ratio and Tuberculosis disease progression in genetically distinct populations of macaques.

Sibley L, Gooch K, Wareham A, Gray S, Chancellor A, Dowall S, Bate S, Marriott A, Dennis M, White AD, Marsh PD, Fletcher H, Sharpe S.

Sci Rep. 2019 Mar 4;9(1):3340. doi: 10.1038/s41598-019-39819-6.

8.

Regarding "Long-Term Evaluation of Percutaneous Groin Access for EVAR".

White AD, Hazar C, Jarosz D, Walker P, Tingerides C.

Cardiovasc Intervent Radiol. 2019 May;42(5):788. doi: 10.1007/s00270-019-02174-0. Epub 2019 Feb 7. No abstract available.

PMID:
30734068
9.

Ca2+ allostery in PTH-receptor signaling.

White AD, Fang F, Jean-Alphonse FG, Clark LJ, An HJ, Liu H, Zhao Y, Reynolds SL, Lee S, Xiao K, Sutkeviciute I, Vilardaga JP.

Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3294-3299. doi: 10.1073/pnas.1814670116. Epub 2019 Feb 4.

10.

Luminescence-activated nucleotide cyclase regulates spatial and temporal cAMP synthesis.

Naim N, White AD, Reece JM, Wankhede M, Zhang X, Vilardaga JP, Altschuler DL.

J Biol Chem. 2019 Jan 25;294(4):1095-1103. doi: 10.1074/jbc.AC118.004905. Epub 2018 Dec 17.

11.

Encoding and selecting coarse-grain mapping operators with hierarchical graphs.

Chakraborty M, Xu C, White AD.

J Chem Phys. 2018 Oct 7;149(13):134106. doi: 10.1063/1.5040114.

PMID:
30292213
12.

Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N-([1,2,4]Triazolo[4,3- a]pyridin-3-yl)methane-sulfonamides as Potent and Selective hNaV1.7 Inhibitors for the Treatment of Pain.

Focken T, Chowdhury S, Zenova A, Grimwood ME, Chabot C, Sheng T, Hemeon I, Decker SM, Wilson M, Bichler P, Jia Q, Sun S, Young C, Lin S, Goodchild SJ, Shuart NG, Chang E, Xie Z, Li B, Khakh K, Bankar G, Waldbrook M, Kwan R, Nelkenbrecher K, Karimi Tari P, Chahal N, Sojo L, Robinette CL, White AD, Chen CA, Zhang Y, Pang J, Chang JH, Hackos DH, Johnson JP Jr, Cohen CJ, Ortwine DF, Sutherlin DP, Dehnhardt CM, Safina BS.

J Med Chem. 2018 Jun 14;61(11):4810-4831. doi: 10.1021/acs.jmedchem.7b01826. Epub 2018 May 23.

PMID:
29737846
13.

High Fat Diet Attenuates the Anticontractile Activity of Aortic PVAT via a Mechanism Involving AMPK and Reduced Adiponectin Secretion.

Almabrouk TAM, White AD, Ugusman AB, Skiba DS, Katwan OJ, Alganga H, Guzik TJ, Touyz RM, Salt IP, Kennedy S.

Front Physiol. 2018 Feb 9;9:51. doi: 10.3389/fphys.2018.00051. eCollection 2018.

14.

Multiscale Kinetic Modeling Reveals an Ensemble of Cl-/H+ Exchange Pathways in ClC-ec1 Antiporter.

Mayes HB, Lee S, White AD, Voth GA, Swanson JMJ.

J Am Chem Soc. 2018 Feb 7;140(5):1793-1804. doi: 10.1021/jacs.7b11463. Epub 2018 Jan 30.

15.

An aerosol challenge model of tuberculosis in Mauritian cynomolgus macaques.

Sharpe SA, White AD, Sibley L, Gleeson F, Hall GA, Basaraba RJ, McIntyre A, Clark SO, Gooch K, Marsh PD, Williams A, Dennis MJ.

PLoS One. 2017 Mar 8;12(3):e0171906. doi: 10.1371/journal.pone.0171906. eCollection 2017.

16.

The influence of haemoglobin and iron on in vitro mycobacterial growth inhibition assays.

Tanner R, O'Shea MK, White AD, Müller J, Harrington-Kandt R, Matsumiya M, Dennis MJ, Parizotto EA, Harris S, Stylianou E, Naranbhai V, Bettencourt P, Drakesmith H, Sharpe S, Fletcher HA, McShane H.

Sci Rep. 2017 Mar 3;7:43478. doi: 10.1038/srep43478. Erratum in: Sci Rep. 2019 Apr 3;9(1):5596.

17.

Communication: Improved ab initio molecular dynamics by minimally biasing with experimental data.

White AD, Knight C, Hocky GM, Voth GA.

J Chem Phys. 2017 Jan 28;146(4):041102. doi: 10.1063/1.4974837.

PMID:
28147531
18.

The Problem with Big Data: Operating on Smaller Datasets to Bridge the Implementation Gap.

Mann RP, Mushtaq F, White AD, Mata-Cervantes G, Pike T, Coker D, Murdoch S, Hiles T, Smith C, Berridge D, Hinchliffe S, Hall G, Smye S, Wilkie RM, Lodge JP, Mon-Williams M.

Front Public Health. 2016 Dec 1;4:248. eCollection 2016.

19.

Activation of AMP-activated protein kinase rapidly suppresses multiple pro-inflammatory pathways in adipocytes including IL-1 receptor-associated kinase-4 phosphorylation.

Mancini SJ, White AD, Bijland S, Rutherford C, Graham D, Richter EA, Viollet B, Touyz RM, Palmer TM, Salt IP.

Mol Cell Endocrinol. 2017 Jan 15;440:44-56. doi: 10.1016/j.mce.2016.11.010. Epub 2016 Nov 11.

20.

Laparoscopic Motor Learning and Workspace Exploration.

White AD, Mushtaq F, Giles O, Wood ML, Mole C, Culmer PR, Wilkie RM, Mon-Williams M, Lodge JPA.

J Surg Educ. 2016 Nov - Dec;73(6):992-998. doi: 10.1016/j.jsurg.2016.05.001. Epub 2016 Jun 16.

21.

A Direct Method for Incorporating Experimental Data into Multiscale Coarse-Grained Models.

Dannenhoffer-Lafage T, White AD, Voth GA.

J Chem Theory Comput. 2016 May 10;12(5):2144-53. doi: 10.1021/acs.jctc.6b00043. Epub 2016 Apr 15.

PMID:
27045328
22.

Designing free energy surfaces that match experimental data with metadynamics.

White AD, Dama JF, Voth GA.

J Chem Theory Comput. 2015 Jun 9;11(6):2451-60. doi: 10.1021/acs.jctc.5b00178. Epub 2015 May 14.

PMID:
26575545
23.

Inconsistent reporting of minimally invasive surgery errors.

White AD, Skelton M, Mushtaq F, Pike TW, Mon-Williams M, Lodge JP, Wilkie RM.

Ann R Coll Surg Engl. 2015 Nov;97(8):608-12. doi: 10.1308/rcsann.2015.0038.

24.

Evaluation of the Immunogenicity of Mycobacterium bovis BCG Delivered by Aerosol to the Lungs of Macaques.

White AD, Sarfas C, West K, Sibley LS, Wareham AS, Clark S, Dennis MJ, Williams A, Marsh PD, Sharpe SA.

Clin Vaccine Immunol. 2015 Sep;22(9):992-1003. doi: 10.1128/CVI.00289-15. Epub 2015 Jun 24.

25.

Impact of the new fast track kidney allocation scheme for declined kidneys in the United Kingdom.

White AD, Roberts H, Ecuyer C, Brady K, Pathak S, Clark B, Hostert LH, Attia MS, Wellberry-Smith M, Hudson A, Ahmad N.

Clin Transplant. 2015 Oct;29(10):872-81. doi: 10.1111/ctr.12576. Epub 2015 Sep 28.

PMID:
26094680
26.

Learning curve evaluation using cumulative summation analysis-a clinical example of pediatric robot-assisted laparoscopic pyeloplasty.

Cundy TP, Gattas NE, White AD, Najmaldin AS.

J Pediatr Surg. 2015 Aug;50(8):1368-73. doi: 10.1016/j.jpedsurg.2014.12.025. Epub 2015 Jan 8.

PMID:
25783405
27.

Contextual effects on activity profiles of domestic field hockey during competition and training.

White AD, MacFarlane NG.

Hum Mov Sci. 2015 Apr;40:422-31. doi: 10.1016/j.humov.2015.01.007. Epub 2015 Feb 16.

PMID:
25697973
28.

Outcome after liver resection in patients presenting with simultaneous hepatopulmonary colorectal metastases.

Dave RV, Pathak S, White AD, Hidalgo E, Prasad KR, Lodge JP, Milton R, Toogood GJ.

Br J Surg. 2015 Feb;102(3):261-8. doi: 10.1002/bjs.9737. Epub 2014 Dec 22.

PMID:
25529247
29.

The management of the surgical complications of HELLP syndrome.

Wilson SG, White AD, Young AL, Davies MH, Pollard SG.

Ann R Coll Surg Engl. 2014 Oct;96(7):512-6. doi: 10.1308/003588414X13946184901362. Review.

30.

Simplified fast-track laparoscopic Roux-en-Y gastric bypass.

Pike TW, White AD, Snook NJ, Dean SG, Lodge JP.

Obes Surg. 2015 Mar;25(3):413-7. doi: 10.1007/s11695-014-1408-6.

PMID:
25194561
31.

The learning curve of robot-assisted laparoscopic fundoplication in children: a prospective evaluation and CUSUM analysis.

Cundy TP, Rowland SP, Gattas NE, White AD, Najmaldin AS.

Int J Med Robot. 2015 Jun;11(2):141-9. doi: 10.1002/rcs.1610. Epub 2014 Aug 25.

PMID:
25156491
32.

Characterizing Social and Recreational Programming in Assisted Living.

Hanson HM, Hoppmann CA, Condon K, Davis J, Feldman F, Friesen M, Leung PM, White AD, Sims-Gould J, Ashe MC.

Can J Aging. 2014 Sep;33(3):285-95. doi: 10.1017/S0714980814000178. Epub 2014 Aug 11.

PMID:
25110902
33.

Efficient and Minimal Method to Bias Molecular Simulations with Experimental Data.

White AD, Voth GA.

J Chem Theory Comput. 2014 Aug 12;10(8):3023-30. doi: 10.1021/ct500320c. Epub 2014 Jul 2.

PMID:
26588273
34.

Analysis of international competition and training in men's field hockey by global positioning system and inertial sensor technology.

White AD, MacFarlane NG.

J Strength Cond Res. 2015 Jan;29(1):137-43. doi: 10.1519/JSC.0000000000000600.

PMID:
24978837
35.

cis-1-Oxo-heterocyclyl-4-amido cyclohexane derivatives as NPY5 receptor antagonists.

Burns JF, Chen B, Chen CA, Doller D, Edelmenky E, Jiang Y, Peterson JM, Sabio M, Weiss J, White AD, Wu L, Bhardwaj R, Chandrasena G, Boyle NJ, Huang X.

Bioorg Med Chem Lett. 2014 Mar 15;24(6):1458-61. doi: 10.1016/j.bmcl.2014.02.023. Epub 2014 Feb 15.

PMID:
24582476
36.

Biologically inspired stealth peptide-capped gold nanoparticles.

Nowinski AK, White AD, Keefe AJ, Jiang S.

Langmuir. 2014 Feb 25;30(7):1864-70. doi: 10.1021/la404980g. Epub 2014 Feb 7.

PMID:
24483727
37.

Nodular regenerative hyperplasia (NRH) complicating oxaliplatin chemotherapy in patients undergoing resection of colorectal liver metastases.

Morris-Stiff G, White AD, Gomez D, Cameron IC, Farid S, Toogood GJ, Lodge JP, Prasad KR.

Eur J Surg Oncol. 2014 Aug;40(8):1016-20. doi: 10.1016/j.ejso.2013.09.015. Epub 2013 Nov 1.

PMID:
24370284
38.

Difference of carboxybetaine and oligo(ethylene glycol) moieties in altering hydrophobic interactions: a molecular simulation study.

Shao Q, White AD, Jiang S.

J Phys Chem B. 2014 Jan 9;118(1):189-94. doi: 10.1021/jp410224w. Epub 2013 Dec 20.

PMID:
24328129
39.

Minimally invasive surgery training using multiple port sites to improve performance.

White AD, Giles O, Sutherland RJ, Ziff O, Mon-Williams M, Wilkie RM, Lodge JP.

Surg Endosc. 2014 Apr;28(4):1188-93.

40.

Fused thiazolyl alkynes as potent mGlu5 receptor positive allosteric modulators.

Packiarajan M, Grenon M, Zorn S, Hopper AT, White AD, Chandrasena G, Pu X, Brodbeck RM, Robichaud AJ.

Bioorg Med Chem Lett. 2013 Jul 15;23(14):4037-43. doi: 10.1016/j.bmcl.2013.05.070. Epub 2013 May 30.

PMID:
23770058
41.

Free energy of solvated salt bridges: a simulation and experimental study.

White AD, Keefe AJ, Ella-Menye JR, Nowinski AK, Shao Q, Pfaendtner J, Jiang S.

J Phys Chem B. 2013 Jun 20;117(24):7254-9. doi: 10.1021/jp4024469. Epub 2013 Jun 11.

PMID:
23697872
42.

Evaluation of the safety and immunogenicity of a candidate tuberculosis vaccine, MVA85A, delivered by aerosol to the lungs of macaques.

White AD, Sibley L, Dennis MJ, Gooch K, Betts G, Edwards N, Reyes-Sandoval A, Carroll MW, Williams A, Marsh PD, McShane H, Sharpe SA.

Clin Vaccine Immunol. 2013 May;20(5):663-72. doi: 10.1128/CVI.00690-12. Epub 2013 Feb 27.

43.

Time-on-pitch or full-game GPS analysis procedures for elite field hockey?

White AD, MacFarlane N.

Int J Sports Physiol Perform. 2013 Sep;8(5):549-55. Epub 2013 Feb 14.

PMID:
23412758
44.

Standardizing and simplifying analysis of peptide library data.

White AD, Keefe AJ, Nowinski AK, Shao Q, Caldwell K, Jiang S.

J Chem Inf Model. 2013 Feb 25;53(2):493-9. doi: 10.1021/ci300484q. Epub 2013 Feb 4.

PMID:
23327110
45.

Directly functionalizable surface platform for protein arrays in undiluted human blood plasma.

Brault ND, White AD, Taylor AD, Yu Q, Jiang S.

Anal Chem. 2013 Feb 5;85(3):1447-53. doi: 10.1021/ac303462u. Epub 2013 Jan 17.

PMID:
23298516
46.

Role of nonspecific interactions in molecular chaperones through model-based bioinformatics.

White AD, Huang W, Jiang S.

Biophys J. 2012 Dec 19;103(12):2484-91. doi: 10.1016/j.bpj.2012.10.040. Epub 2012 Dec 18.

47.

Meta-analysis of prospective trials determining the short- and mid-term effect of elective open and endovascular repair of abdominal aortic aneurysms on quality of life.

Coughlin PA, Jackson D, White AD, Bailey MA, Farrow C, Scott DJ, Howell SJ.

Br J Surg. 2013 Mar;100(4):448-55. doi: 10.1002/bjs.9018. Epub 2012 Dec 19. Review.

PMID:
23254440
48.

Screening nonspecific interactions of peptides without background interference.

Keefe AJ, Caldwell KB, Nowinski AK, White AD, Thakkar A, Jiang S.

Biomaterials. 2013 Mar;34(8):1871-7. doi: 10.1016/j.biomaterials.2012.11.014. Epub 2012 Dec 14.

49.

Implantable versus cuffed external central venous catheters for the management of children and adolescents with acute lymphoblastic leukaemia.

White AD, Othman D, Dawrant MJ, Sohrabi S, Young AL, Squire R.

Pediatr Surg Int. 2012 Dec;28(12):1195-9. doi: 10.1007/s00383-012-3213-4. Epub 2012 Nov 23.

PMID:
23178960
50.

Loss of OPA1 disturbs cellular calcium homeostasis and sensitizes for excitotoxicity.

Kushnareva YE, Gerencser AA, Bossy B, Ju WK, White AD, Waggoner J, Ellisman MH, Perkins G, Bossy-Wetzel E.

Cell Death Differ. 2013 Feb;20(2):353-65. doi: 10.1038/cdd.2012.128. Epub 2012 Nov 9.

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