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Items: 1 to 50 of 109

1.

Using White-tailed Deer (Odocoileus virginianus) in Infectious Disease Research.

Palmer MV, Cox RJ, Waters WR, Thacker TC, Whipple DL.

J Am Assoc Lab Anim Sci. 2017 Jul 1;56(4):350-360.

2.

Design of high-throughput screening assays and identification of a SUMO1-specific small molecule chemotype targeting the SUMO-interacting motif-binding surface.

Alontaga AY, Li Y, Chen CH, Ma CT, Malany S, Key DE, Sergienko E, Sun Q, Whipple DA, Matharu DS, Li B, Vega R, Li YJ, Schoenen FJ, Blagg BS, Chung TD, Chen Y.

ACS Comb Sci. 2015 Apr 13;17(4):239-46. doi: 10.1021/co500181b. Epub 2015 Mar 23.

3.

Potency enhancement of the κ-opioid receptor antagonist probe ML140 through sulfonamide constraint utilizing a tetrahydroisoquinoline motif.

Frankowski KJ, Slauson SR, Lovell KM, Phillips AM, Streicher JM, Zhou L, Whipple DA, Schoenen FJ, Prisinzano TE, Bohn LM, Aubé J.

Bioorg Med Chem. 2015 Jul 15;23(14):3948-56. doi: 10.1016/j.bmc.2014.12.033. Epub 2014 Dec 23.

4.

Inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase.

Schoenen FJ, Whipple D, Baillargeon P, Brown CL, Chase P, Ferguson J, Fernandez-Vega V, Hodder P, Mathew R, Neuenswander B, Porubsky P, Rogers S, Skinner-Adams T, Sosa M, Spicer T, To J, Tower NA, Trenholme KR, Wang J, Weiner WS, Aubé J, Rosen H, White EL, Gardiner DL, Dalton JP.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2013 Dec 12 [updated 2014 Sep 18].

5.

Inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase.

Schoenen FJ, Weiner WS, Baillargeon P, Brown CL, Chase P, Ferguson J, Fernandez-Vega V, Ghosh P, Hodder P, Krise JP, Matharu DS, Neuenswander B, Porubsky P, Rogers S, Skinner-Adams T, Sosa M, Spicer T, To J, Tower NA, Trenholme KR, Wang J, Whipple D, Aubé J, Rosen H, White EL, Dalton JP, Gardiner DL.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2013 Apr 12 [updated 2014 Sep 18].

6.

Identification of Potent and Selective Inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PfM18AAP) of Human Malaria via High-Throughput Screening.

Spicer T, Fernandez-Vega V, Chase P, Scampavia L, To J, Dalton JP, Da Silva FL, Skinner-Adams TS, Gardiner DL, Trenholme KR, Brown CL, Ghosh P, Porubsky P, Wang JL, Whipple DA, Schoenen FJ, Hodder P.

J Biomol Screen. 2014 Aug;19(7):1107-15. doi: 10.1177/1087057114525852. Epub 2014 Mar 11.

7.

Reliability of temporal artery thermometers.

McConnell E, Senseney D, George SS, Whipple D.

Medsurg Nurs. 2013 Nov-Dec;22(6):387-92. No abstract available.

PMID:
24600936
8.

High-impact animal health research conducted at the USDA's National Animal Disease Center.

Bannantine JP, Olsen SC, Kehrli ME Jr, Stanton TB, Casas E, Whipple DL, Zuelke KA.

Vet Microbiol. 2013 Aug 30;165(3-4):224-33. doi: 10.1016/j.vetmic.2013.04.010. Epub 2013 Apr 12. Review.

PMID:
23642415
9.

Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy.

Frankowski KJ, Hedrick MP, Gosalia P, Li K, Shi S, Whipple D, Ghosh P, Prisinzano TE, Schoenen FJ, Su Y, Vasile S, Sergienko E, Gray W, Hariharan S, Milan L, Heynen-Genel S, Mangravita-Novo A, Vicchiarelli M, Smith LH, Streicher JM, Caron MG, Barak LS, Bohn LM, Chung TD, Aubé J.

ACS Chem Neurosci. 2012 Mar 21;3(3):221-236. Epub 2012 Jan 20.

10.

Ionic liquid-mediated selective conversion of CO₂ to CO at low overpotentials.

Rosen BA, Salehi-Khojin A, Thorson MR, Zhu W, Whipple DT, Kenis PJ, Masel RI.

Science. 2011 Nov 4;334(6056):643-4. doi: 10.1126/science.1209786. Epub 2011 Sep 29.

11.

Preparation, gram-negative antibacterial activity, and hydrolytic stability of novel siderophore-conjugated monocarbam diols.

Flanagan ME, Brickner SJ, Lall M, Casavant J, Deschenes L, Finegan SM, George DM, Granskog K, Hardink JR, Huband MD, Hoang T, Lamb L, Marra A, Mitton-Fry M, Mueller JP, Mullins LM, Noe MC, O'Donnell JP, Pattavina D, Penzien JB, Schuff BP, Sun J, Whipple DA, Young J, Gootz TD.

ACS Med Chem Lett. 2011 Mar 2;2(5):385-90. doi: 10.1021/ml200012f. eCollection 2011 May 12.

12.

Selective KOP Receptor Antagonists: Probe 1.

Hedrick MP, Gosalia P, Frankowski K, Whipple DA, Shi S, Prisinzano TE, Schoenen F, Aubé J, Su Y, Vasile S, Sergienko E, Gray W, Hariharan S, Milan L, Heynen-Genel S, Chung TDY, Dad S, Caron M, Bohn LM, Barak LS.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2010 Feb 28 [updated 2010 Oct 4].

13.

Use of the intradermal tuberculin test in a herd of captive elk (Cervus elaphus nelsoni) naturally infected with Mycobacterium bovis.

Palmer MV, Whipple DL, Payeur JB, Bolin CA.

J Vet Diagn Invest. 2011 Mar;23(2):363-6.

PMID:
21398465
14.

Discovery of CP-690,550: a potent and selective Janus kinase (JAK) inhibitor for the treatment of autoimmune diseases and organ transplant rejection.

Flanagan ME, Blumenkopf TA, Brissette WH, Brown MF, Casavant JM, Shang-Poa C, Doty JL, Elliott EA, Fisher MB, Hines M, Kent C, Kudlacz EM, Lillie BM, Magnuson KS, McCurdy SP, Munchhof MJ, Perry BD, Sawyer PS, Strelevitz TJ, Subramanyam C, Sun J, Whipple DA, Changelian PS.

J Med Chem. 2010 Dec 23;53(24):8468-84. doi: 10.1021/jm1004286. Epub 2010 Nov 24.

PMID:
21105711
15.

Discovery of azetidinyl ketolides for the treatment of susceptible and multidrug resistant community-acquired respiratory tract infections.

Magee TV, Ripp SL, Li B, Buzon RA, Chupak L, Dougherty TJ, Finegan SM, Girard D, Hagen AE, Falcone MJ, Farley KA, Granskog K, Hardink JR, Huband MD, Kamicker BJ, Kaneko T, Knickerbocker MJ, Liras JL, Marra A, Medina I, Nguyen TT, Noe MC, Obach RS, O'Donnell JP, Penzien JB, Reilly UD, Schafer JR, Shen Y, Stone GG, Strelevitz TJ, Sun J, Tait-Kamradt A, Vaz AD, Whipple DA, Widlicka DW, Wishka DG, Wolkowski JP, Flanagan ME.

J Med Chem. 2009 Dec 10;52(23):7446-57. doi: 10.1021/jm900729s.

PMID:
19775168
16.

The specificity of JAK3 kinase inhibitors.

Changelian PS, Moshinsky D, Kuhn CF, Flanagan ME, Munchhof MJ, Harris TM, Whipple DA, Doty JL, Sun J, Kent CR, Magnuson KS, Perregaux DG, Sawyer PS, Kudlacz EM.

Blood. 2008 Feb 15;111(4):2155-7. Epub 2007 Dec 19. Erratum in: Blood. 2009 Oct 1;114(14):3132. Dosage error in article text; Whipple, David A [added].

18.

Top down mass spectrometry of < 60-kDa proteins from Methanosarcina acetivorans using quadrupole FRMS with automated octopole collisionally activated dissociation.

Patrie SM, Ferguson JT, Robinson DE, Whipple D, Rother M, Metcalf WW, Kelleher NL.

Mol Cell Proteomics. 2006 Jan;5(1):14-25.

19.

Investigation of the transmission of Mycobacterium bovis from deer to cattle through indirect contact.

Palmer MV, Waters WR, Whipple DL.

Am J Vet Res. 2004 Nov;65(11):1483-9.

PMID:
15566085
20.

CD80 and CD86, but not CD154, augment DNA vaccine-induced protection in experimental bovine tuberculosis.

Maue AC, Waters WR, Palmer MV, Whipple DL, Minion FC, Brown WC, Estes DM.

Vaccine. 2004 Dec 21;23(6):769-79.

PMID:
15542201
21.

Antigen recognition by serum antibodies in white-tailed deer (Odocoileus virginianus) experimentally infected with Mycobacterium bovis.

Waters WR, Palmer MV, Bannantine JP, Whipple DL, Greenwald R, Esfandiari J, Andersen P, McNair J, Pollock JM, Lyashchenko KP.

Clin Diagn Lab Immunol. 2004 Sep;11(5):849-55.

22.

Use of recombinant ESAT-6:CFP-10 fusion protein for differentiation of infections of cattle by Mycobacterium bovis and by M. avium subsp. avium and M. avium subsp. paratuberculosis.

Waters WR, Nonnecke BJ, Palmer MV, Robbe-Austermann S, Bannantine JP, Stabel JR, Whipple DL, Payeur JB, Estes DM, Pitzer JE, Minion FC.

Clin Diagn Lab Immunol. 2004 Jul;11(4):729-35.

23.

Construction of a hybrid quadrupole/Fourier transform ion cyclotron resonance mass spectrometer for versatile MS/MS above 10 kDa.

Patrie SM, Charlebois JP, Whipple D, Kelleher NL, Hendrickson CL, Quinn JP, Marshall AG, Mukhopadhyay B.

J Am Soc Mass Spectrom. 2004 Jul;15(7):1099-108.

24.

Shared feed as a means of deer-to-deer transmission of Mycobacterium bovis.

Palmer MV, Waters WR, Whipple DL.

J Wildl Dis. 2004 Jan;40(1):87-91.

PMID:
15137492
25.

Immune responses of white-tailed deer (Odocoileus virginianus) to Mycobacterium bovis BCG vaccination.

Waters WR, Palmer MV, Whipple DL, Slaughter RE, Jones SL.

J Wildl Dis. 2004 Jan;40(1):66-78.

PMID:
15137490
26.

The sensitivity of gross necropsy, caudal fold and comparative cervical tests for the diagnosis of bovine tuberculosis.

Norby B, Bartlett PC, Fitzgerald SD, Granger LM, Bruning-Fann CS, Whipple DL, Payeur JB.

J Vet Diagn Invest. 2004 Mar;16(2):126-31.

PMID:
15053363
27.
28.

Aerosol exposure of white-tailed deer (Odocoileus virginianus) to Mycobacterium bovis.

Palmer MV, Waters WR, Whipple DL.

J Wildl Dis. 2003 Oct;39(4):817-23.

PMID:
14733276
29.

Mycobacterium bovis infection of vitamin D-deficient NOS2-/- mice.

Waters WR, Palmer MV, Nonnecke BJ, Whipple DL, Horst RL.

Microb Pathog. 2004 Jan;36(1):11-7.

PMID:
14643635
30.

Prevention of organ allograft rejection by a specific Janus kinase 3 inhibitor.

Changelian PS, Flanagan ME, Ball DJ, Kent CR, Magnuson KS, Martin WH, Rizzuti BJ, Sawyer PS, Perry BD, Brissette WH, McCurdy SP, Kudlacz EM, Conklyn MJ, Elliott EA, Koslov ER, Fisher MB, Strelevitz TJ, Yoon K, Whipple DA, Sun J, Munchhof MJ, Doty JL, Casavant JM, Blumenkopf TA, Hines M, Brown MF, Lillie BM, Subramanyam C, Shang-Poa C, Milici AJ, Beckius GE, Moyer JD, Su C, Woodworth TG, Gaweco AS, Beals CR, Littman BH, Fisher DA, Smith JF, Zagouras P, Magna HA, Saltarelli MJ, Johnson KS, Nelms LF, Des Etages SG, Hayes LS, Kawabata TT, Finco-Kent D, Baker DL, Larson M, Si MS, Paniagua R, Higgins J, Holm B, Reitz B, Zhou YJ, Morris RE, O'Shea JJ, Borie DC.

Science. 2003 Oct 31;302(5646):875-8.

31.

Mycobacterium bovis bacille Calmette-Guerin vaccination of cattle: activation of bovine CD4+ and gamma delta TCR+ cells and modulation by 1,25-dihydroxyvitamin D3.

Waters WR, Nonnecke BJ, Foote MR, Maue AC, Rahner TE, Palmer MV, Whipple DL, Horst RL, Estes DM.

Tuberculosis (Edinb). 2003;83(5):287-97.

PMID:
12972342
32.

Arcanobacterium pyogenes as a cause of fatal pleuropneumonia after capture and transport of white-tailed deer (Odocoileus virginianus).

Palmer MV, Whipple DL.

J Vet Diagn Invest. 1999 Sep;11(5):468-71. No abstract available.

PMID:
12968764
34.

Epidemiology and diagnosis of Mycobacterium tuberculosis in captive Asian elephants (Elephas maximus).

Mikota SK, Peddie L, Peddie J, Isaza R, Dunker F, West G, Lindsay W, Larsen RS, Salman MD, Chatterjee D, Payeur J, Whipple D, Thoen C, Davis DS, Sedgwick C, Montali RJ, Ziccardi M, Maslow J.

J Zoo Wildl Med. 2001 Mar;32(1):1-16.

PMID:
12790389
35.

Aerosol delivery of virulent Mycobacterium bovis to cattle.

Palmer MV, Waters WR, Whipple DL.

Tuberculosis (Edinb). 2002;82(6):275-82.

PMID:
12623270
36.

Immune responses of elk to Mycobacterium bovis bacillus Calmette Guerin vaccination.

Waters WR, Palmer MV, Olsen SC, Sacco RE, Whipple DL.

Vaccine. 2003 Mar 28;21(13-14):1518-26.

PMID:
12615449
37.

Expression of L-Selectin (CD62L), CD44, and CD25 on activated bovine T cells.

Waters WR, Rahner TE, Palmer MV, Cheng D, Nonnecke BJ, Whipple DL.

Infect Immun. 2003 Jan;71(1):317-26.

38.

Milk containing Mycobacterium bovis as a source of infection for white-tailed deer fawns (Odocoileus virginianus).

Palmer MV, Waters WR, Whipple DL.

Tuberculosis (Edinb). 2002;82(4-5):161-5.

PMID:
12464487
39.
40.

Prevalence of Mycobacterium bovis infection in cervids on privately owned ranches.

Kaneene JB, VanderKlok M, Bruning-Fann CS, Palmer MV, Whipple DL, Schmitt SM, Miller R.

J Am Vet Med Assoc. 2002 Mar 1;220(5):656-9.

PMID:
12418527
41.

Bovine tuberculosis in Michigan wildlife.

Payeur JB, Church S, Mosher L, Robinson-Dunn B, Schmitt S, Whipple D.

Ann N Y Acad Sci. 2002 Oct;969:259-61. Review.

PMID:
12381602
42.

Mycobacterial isolations in captive elephants in the United States.

Payeur JB, Jarnagin JL, Marquardt JG, Whipple DL.

Ann N Y Acad Sci. 2002 Oct;969:256-8. Review.

PMID:
12381601
43.

Apoptosis in lymph node granulomas from white-tailed deer (Odocoileus virginianus) experimentally infected with Mycobacterium bovis.

Palmer MV, Gosch G, Lyon R, Waters WR, Whipple DL.

J Comp Pathol. 2002 Jul;127(1):7-13.

PMID:
12354540
44.

Tonsillar lesions in white-tailed deer (Odocoileus virginianus) naturally infected with Mycobacterium bovis.

Palmer MV, Whipple DL, Butler KL, Fitzgerald SD, Bruning-Fann CS, Schmitt SM.

Vet Rec. 2002 Aug 3;151(5):149-50. No abstract available.

PMID:
12199435
45.

Nitric oxide production as an indication of Mycobacterium bovis infection in white-tailed deer (Odocoileus virginianus).

Waters WR, Palmer MV, Sacco RE, Whipple DL.

J Wildl Dis. 2002 Apr;38(2):338-43.

PMID:
12038133
46.

Susceptibility of raccoons (Procyon lotor) to infection with Mycobacterium bovis.

Palmer MV, Waters WR, Whipple DL.

J Wildl Dis. 2002 Apr;38(2):266-74.

PMID:
12038124
47.
48.

Tuberculin skin testing in white-tailed deer (Odocoileus virginianus).

Palmer MV, Whipple DL, Waters WR.

J Vet Diagn Invest. 2001 Nov;13(6):530-3.

PMID:
11724147
49.

Modulation of Mycobacterium bovis-specific responses of bovine peripheral blood mononuclear cells by 1,25-dihydroxyvitamin D(3).

Waters WR, Nonnecke BJ, Rahner TE, Palmer MV, Whipple DL, Horst RL.

Clin Diagn Lab Immunol. 2001 Nov;8(6):1204-12.

50.

Abomasal ulcers in captive white-tailed deer (Odocoileus virginianus).

Palmer MV, Waters WR, Whipple DL.

J Comp Pathol. 2001 Aug-Oct;125(2-3):224-7.

PMID:
11578141

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