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Items: 1 to 50 of 242

1.

Structure of a rabies virus polymerase complex from electron cryo-microscopy.

Horwitz JA, Jenni S, Harrison SC, Whelan SPJ.

Proc Natl Acad Sci U S A. 2020 Jan 17. pii: 201918809. doi: 10.1073/pnas.1918809117. [Epub ahead of print]

PMID:
31953264
2.

Increased summer food supply decreases non-breeding movement in black-legged kittiwakes.

Whelan S, Hatch SA, Irons DB, McKnight A, Elliott KH.

Biol Lett. 2020 Jan;16(1):20190725. doi: 10.1098/rsbl.2019.0725. Epub 2020 Jan 15.

PMID:
31937217
3.

Temporal and tissue-specific activation of aryl hydrocarbon receptor in discrete mouse models of kidney disease.

Walker JA, Richards S, Belghasem ME, Arinze N, Yoo SB, Tashjian JY, Whelan SA, Lee N, Kolachalama VB, Francis J, Ravid K, Sherr D, Chitalia VC.

Kidney Int. 2019 Oct 30. pii: S0085-2538(19)31037-3. doi: 10.1016/j.kint.2019.09.029. [Epub ahead of print]

PMID:
31932072
4.

A broad-spectrum antiviral molecule, QL47, selectively inhibits eukaryotic translation.

de Wispelaere M, Carocci M, Burri DJ, Neidermyer WJ Jr, Olson CM, Roggenbach I, Liang Y, Wang J, Whelan SPJ, Gray NS, Yang PL.

J Biol Chem. 2019 Dec 30. pii: jbc.RA119.011132. doi: 10.1074/jbc.RA119.011132. [Epub ahead of print]

5.

Structure of the Vesicular Stomatitis Virus L Protein in Complex with Its Phosphoprotein Cofactor.

Jenni S, Bloyet LM, Diaz-Avalos R, Liang B, Whelan SPJ, Grigorieff N, Harrison SC.

Cell Rep. 2020 Jan 7;30(1):53-60.e5. doi: 10.1016/j.celrep.2019.12.024.

6.

Metabolites in a mouse cancer model enhance venous thrombogenicity through the aryl hydrocarbon receptor-tissue factor axis.

Belghasem M, Roth D, Richards S, Napolene MA, Walker J, Yin W, Arinze N, Lyle C, Spencer C, Francis JM, Thompson C, Andry C, Whelan SA, Lee N, Ravid K, Chitalia VC.

Blood. 2019 Dec 26;134(26):2399-2413. doi: 10.1182/blood.2019001675.

PMID:
31877217
7.

Endotoxin Engages Mitochondrial Quality Control via an iNOS-Reactive Oxygen Species Signaling Pathway in Hepatocytes.

Cyr A, Chambers L, Waltz PK, Whelan SP, Kohut L, Carchman E, Dyer M, Luciano J, Kautza B, Gomez HD, Otterbein LE, Rosengart MR, Shiva S, Zuckerbraun BS.

Oxid Med Cell Longev. 2019 Oct 24;2019:4745067. doi: 10.1155/2019/4745067. eCollection 2019.

8.

Point-of-care blood analyzers measure the nutritional state of eighteen free-living bird species.

Morales A, Frei B, Leung C, Titman R, Whelan S, Benowitz-Fredericks ZM, Elliott KH.

Comp Biochem Physiol A Mol Integr Physiol. 2020 Feb;240:110594. doi: 10.1016/j.cbpa.2019.110594. Epub 2019 Oct 30.

PMID:
31676409
9.

Huffin' and puffin: seabirds use large bills to dissipate heat from energetically demanding flight.

Schraft HA, Whelan S, Elliott KH.

J Exp Biol. 2019 Nov 8;222(Pt 21). pii: jeb212563. doi: 10.1242/jeb.212563.

PMID:
31624096
10.

Vesicular Stomatitis Virus Transcription Is Inhibited by TRIM69 in the Interferon-Induced Antiviral State.

Kueck T, Bloyet LM, Cassella E, Zang T, Schmidt F, Brusic V, Tekes G, Pornillos O, Whelan SPJ, Bieniasz PD.

J Virol. 2019 Nov 26;93(24). pii: e01372-19. doi: 10.1128/JVI.01372-19. Print 2019 Dec 15.

11.

Evaluation of a Companion Robot for Individuals With Dementia: Quantitative Findings of the MARIO Project in an Irish Residential Care Setting.

Barrett E, Burke M, Whelan S, Santorelli A, Oliveira BL, Cavallo F, Dröes RM, Hopper L, Fawcett-Henesy A, Meiland FJM, Mountain G, Moyle W, Raciti M, Pegman G, Teare A, Sancarlo D, Riccardi F, D'Onofrio G, Giuliani F, Russo A, Bleaden A, Greco A, Casey D.

J Gerontol Nurs. 2019 Jul 1;45(7):36-45. doi: 10.3928/00989134-20190531-01.

PMID:
31237660
12.

Global analysis of polysome-associated mRNA in vesicular stomatitis virus infected cells.

Neidermyer WJ Jr, Whelan SPJ.

PLoS Pathog. 2019 Jun 21;15(6):e1007875. doi: 10.1371/journal.ppat.1007875. eCollection 2019 Jun.

13.

Identifying Clusters of High Confidence Homologies in Multiple Sequence Alignments.

Ali RH, Bogusz M, Whelan S.

Mol Biol Evol. 2019 Oct 1;36(10):2340-2351. doi: 10.1093/molbev/msz142.

14.

Sulfated glycosaminoglycans and low-density lipoprotein receptor contribute to Clostridium difficile toxin A entry into cells.

Tao L, Tian S, Zhang J, Liu Z, Robinson-McCarthy L, Miyashita SI, Breault DT, Gerhard R, Oottamasathien S, Whelan SPJ, Dong M.

Nat Microbiol. 2019 Oct;4(10):1760-1769. doi: 10.1038/s41564-019-0464-z. Epub 2019 Jun 3.

15.

Human, Nonhuman Primate, and Bat Cells Are Broadly Susceptible to Tibrovirus Particle Cell Entry.

Caì Y, Yú S, Jangra RK, Postnikova EN, Wada J, Tesh RB, Whelan SPJ, Lauck M, Wiley MR, Finch CL, Radoshitzky SR, O'Connor DH, Palacios G, Chandran K, Chiu CY, Kuhn JH.

Front Microbiol. 2019 Apr 26;10:856. doi: 10.3389/fmicb.2019.00856. eCollection 2019.

16.

Muscle fiber structure in an aging long-lived seabird, the black-legged kittiwake (Rissa tridactyla).

Brown K, Jimenez AG, Whelan S, Lalla K, Hatch SA, Elliott KH.

J Morphol. 2019 Jul;280(7):1061-1070. doi: 10.1002/jmor.21001. Epub 2019 May 11.

PMID:
31077454
17.

RNA ligands activate the Machupo virus polymerase and guide promoter usage.

Pyle JD, Whelan SPJ.

Proc Natl Acad Sci U S A. 2019 May 21;116(21):10518-10524. doi: 10.1073/pnas.1900790116. Epub 2019 May 9.

18.

MARIO Project: Validation and Evidence of Service Robots for Older People with Dementia.

D'Onofrio G, Sancarlo D, Raciti M, Burke M, Teare A, Kovacic T, Cortis K, Murphy K, Barrett E, Whelan S, Dolan A, Russo A, Ricciardi F, Pegman G, Presutti V, Messervey T, Cavallo F, Giuliani F, Bleaden A, Casey D, Greco A.

J Alzheimers Dis. 2019;68(4):1587-1601. doi: 10.3233/JAD-181165.

PMID:
30958360
19.

Improvement in health status with once-daily indacaterol/glycopyrronium 110/50 μg in COPD patients: real-world evidence from an observational study in Ireland.

O'Doherty B, Dorman J, McGrath K, Kelly K, Molony D, Lacey S, Whelan S, Schmid S, Sullivan S.

Ir J Med Sci. 2019 Nov;188(4):1251-1259. doi: 10.1007/s11845-019-02001-y. Epub 2019 Mar 28.

PMID:
30924006
20.

Physicochemical Amino Acid Properties Better Describe Substitution Rates in Large Populations.

Weber CC, Whelan S.

Mol Biol Evol. 2019 Apr 1;36(4):679-690. doi: 10.1093/molbev/msz003.

PMID:
30668757
21.

PVRIG and PVRL2 Are Induced in Cancer and Inhibit CD8+ T-cell Function.

Whelan S, Ophir E, Kotturi MF, Levy O, Ganguly S, Leung L, Vaknin I, Kumar S, Dassa L, Hansen K, Bernados D, Murter B, Soni A, Taube JM, Fader AN, Wang TL, Shih IM, White M, Pardoll DM, Liang SC.

Cancer Immunol Res. 2019 Feb;7(2):257-268. doi: 10.1158/2326-6066.CIR-18-0442. Epub 2019 Jan 18.

PMID:
30659054
22.

The effect of by-product inclusion and concentrate feeding rate on milk production and composition, pasture dry matter intake, and nitrogen excretion of mid-late lactation spring-calving cows grazing a perennial ryegrass-based pasture.

Condren SA, Kelly AK, Lynch MB, Boland TM, Whelan SJ, Grace C, Rajauria G, Pierce KM.

J Dairy Sci. 2019 Feb;102(2):1247-1256. doi: 10.3168/jds.2018-14970. Epub 2018 Dec 20.

PMID:
30580955
23.

Sweat Testing in Ireland

Blake O, Tsang V, Ghori R, Whelan S, Boran G, Linnane B.

Ir Med J. 2018 Aug 13;111(7):789.

PMID:
30520616
24.

Phase Transitions Drive the Formation of Vesicular Stomatitis Virus Replication Compartments.

Heinrich BS, Maliga Z, Stein DA, Hyman AA, Whelan SPJ.

mBio. 2018 Sep 4;9(5). pii: e02290-17. doi: 10.1128/mBio.02290-17.

25.

Reconstruction of the cell entry pathway of an extinct virus.

Robinson-McCarthy LR, McCarthy KR, Raaben M, Piccinotti S, Nieuwenhuis J, Stubbs SH, Bakkers MJG, Whelan SPJ.

PLoS Pathog. 2018 Aug 6;14(8):e1007123. doi: 10.1371/journal.ppat.1007123. eCollection 2018 Aug.

26.

Identification of Potent Ebola Virus Entry Inhibitors with Suitable Properties for in Vivo Studies.

Liu H, Tian Y, Lee K, Krishnan P, Wang MK, Whelan S, Mevers E, Soloveva V, Dedic B, Liu X, Cunningham JM.

J Med Chem. 2018 Jul 26;61(14):6293-6307. doi: 10.1021/acs.jmedchem.8b00704. Epub 2018 Jul 3.

PMID:
29920098
27.

PREQUAL: detecting non-homologous characters in sets of unaligned homologous sequences.

Whelan S, Irisarri I, Burki F.

Bioinformatics. 2018 Nov 15;34(22):3929-3930. doi: 10.1093/bioinformatics/bty448.

PMID:
29868763
28.

STING-dependent translation inhibition restricts RNA virus replication.

Franz KM, Neidermyer WJ, Tan YJ, Whelan SPJ, Kagan JC.

Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):E2058-E2067. doi: 10.1073/pnas.1716937115. Epub 2018 Feb 12.

29.

NRP2 and CD63 Are Host Factors for Lujo Virus Cell Entry.

Raaben M, Jae LT, Herbert AS, Kuehne AI, Stubbs SH, Chou YY, Blomen VA, Kirchhausen T, Dye JM, Brummelkamp TR, Whelan SP.

Cell Host Microbe. 2017 Nov 8;22(5):688-696.e5. doi: 10.1016/j.chom.2017.10.002.

30.
31.

Investigating the Effect of Social Robot Embodiment.

Whelan S, Kouroupetroglou C, Santorelli A, Raciti M, Barrett E, Casey D.

Stud Health Technol Inform. 2017;242:523-526.

PMID:
28873848
32.

Interacting with Dementia: The MARIO Approach.

Kouroupetroglou C, Casey D, Raciti M, Barrett E, D'Onofrio G, Ricciardi F, Giuliani F, Greco A, Sancarlo D, Mannion A, Whelan S, Pegman G, Koumpis A, Reforgiato Recupero D, Kouroupetroglou A, Santorelli A.

Stud Health Technol Inform. 2017;242:38-47.

PMID:
28873774
33.

Human Regulatory Protein Ki-1/57 Is a Target of SUMOylation and Affects PML Nuclear Body Formation.

Saito Â, Souza EE, Costa FC, Meirelles GV, Gonçalves KA, Santos MT, Bressan GC, McComb ME, Costello CE, Whelan SA, Kobarg J.

J Proteome Res. 2017 Sep 1;16(9):3147-3157. doi: 10.1021/acs.jproteome.7b00001. Epub 2017 Jul 31.

34.

Reduced reproductive performance associated with warmer ambient temperatures during incubation in a winter-breeding, food-storing passerine.

Whelan S, Strickland D, Morand-Ferron J, Norris DR.

Ecol Evol. 2017 Mar 23;7(9):3029-3036. doi: 10.1002/ece3.2864. eCollection 2017 May.

35.

Vesicular stomatitis virus N protein-specific single-domain antibody fragments inhibit replication.

Hanke L, Schmidt FI, Knockenhauer KE, Morin B, Whelan SP, Schwartz TU, Ploegh HL.

EMBO Rep. 2017 Jun;18(6):1027-1037. doi: 10.15252/embr.201643764. Epub 2017 Apr 10.

36.

What lies beneath: HSV meningitis in the asymptomatic infant.

Whelan S, Capra L.

Arch Dis Child. 2017 Oct;102(10):987. doi: 10.1136/archdischild-2016-311841. Epub 2017 Feb 2. No abstract available.

PMID:
28154005
37.

The effect of by-product inclusion level on milk production, nutrient digestibility and excretion, and rumen fermentation parameters in lactating dairy cows offered a pasture-based diet.

Whelan SJ, Carey W, Boland TM, Lynch MB, Kelly AK, Rajauria G, Pierce KM.

J Dairy Sci. 2017 Feb;100(2):1055-1062. doi: 10.3168/jds.2016-11600. Epub 2016 Dec 14.

38.

Mechanism of membrane fusion induced by vesicular stomatitis virus G protein.

Kim IS, Jenni S, Stanifer ML, Roth E, Whelan SP, van Oijen AM, Harrison SC.

Proc Natl Acad Sci U S A. 2017 Jan 3;114(1):E28-E36. doi: 10.1073/pnas.1618883114. Epub 2016 Dec 14.

39.

Inferring Trees.

Whelan S, Morrison DA.

Methods Mol Biol. 2017;1525:349-377.

PMID:
27896728
40.

Adult microbiota-deficient mice have distinct dendritic morphological changes: differential effects in the amygdala and hippocampus.

Luczynski P, Whelan SO, O'Sullivan C, Clarke G, Shanahan F, Dinan TG, Cryan JF.

Eur J Neurosci. 2016 Nov;44(9):2654-2666. doi: 10.1111/ejn.13291. Epub 2016 Jul 8.

41.

An In Vitro RNA Synthesis Assay for Rabies Virus Defines Ribonucleoprotein Interactions Critical for Polymerase Activity.

Morin B, Liang B, Gardner E, Ross RA, Whelan SPJ.

J Virol. 2016 Dec 16;91(1). pii: e01508-16. doi: 10.1128/JVI.01508-16. Print 2017 Jan 1.

42.

Phylogenetic Tree Estimation With and Without Alignment: New Distance Methods and Benchmarking.

Bogusz M, Whelan S.

Syst Biol. 2017 Mar 1;66(2):218-231. doi: 10.1093/sysbio/syw074.

PMID:
27633353
43.

Phenotypic lentivirus screens to identify functional single domain antibodies.

Schmidt FI, Hanke L, Morin B, Brewer R, Brusic V, Whelan SP, Ploegh HL.

Nat Microbiol. 2016 Jun 20;1(8):16080. doi: 10.1038/nmicrobiol.2016.80.

44.

Intermediate filaments enable pathogen docking to trigger type 3 effector translocation.

Russo BC, Stamm LM, Raaben M, Kim CM, Kahoud E, Robinson LR, Bose S, Queiroz AL, Herrera BB, Baxt LA, Mor-Vaknin N, Fu Y, Molina G, Markovitz DM, Whelan SP, Goldberg MB.

Nat Microbiol. 2016 Mar 7;1:16025. doi: 10.1038/nmicrobiol.2016.25.

45.

Tissue-resident Eomes(hi) T-bet(lo) CD56(bright) NK cells with reduced proinflammatory potential are enriched in the adult human liver.

Harmon C, Robinson MW, Fahey R, Whelan S, Houlihan DD, Geoghegan J, O'Farrelly C.

Eur J Immunol. 2016 Sep;46(9):2111-20. doi: 10.1002/eji.201646559.

46.

Rabies Internalizes into Primary Peripheral Neurons via Clathrin Coated Pits and Requires Fusion at the Cell Body.

Piccinotti S, Whelan SP.

PLoS Pathog. 2016 Jul 27;12(7):e1005753. doi: 10.1371/journal.ppat.1005753. eCollection 2016 Jul.

47.

Production of immunogenic West Nile virus-like particles using a herpes simplex virus 1 recombinant vector.

Taylor TJ, Diaz F, Colgrove RC, Bernard KA, DeLuca NA, Whelan SPJ, Knipe DM.

Virology. 2016 Sep;496:186-193. doi: 10.1016/j.virol.2016.06.006. Epub 2016 Jun 20.

48.

A Single Residue in Ebola Virus Receptor NPC1 Influences Cellular Host Range in Reptiles.

Ndungo E, Herbert AS, Raaben M, Obernosterer G, Biswas R, Miller EH, Wirchnianski AS, Carette JE, Brummelkamp TR, Whelan SP, Dye JM, Chandran K.

mSphere. 2016 Mar 30;1(2). pii: e00007-16. doi: 10.1128/mSphere.00007-16. eCollection 2016 Mar-Apr.

49.

Correction for Soh and Whelan, Tracking the Fate of Genetically Distinct Vesicular Stomatitis Virus Matrix Proteins Highlights the Role for Late Domains in Assembly.

Soh TK, Whelan SPJ.

J Virol. 2016 May 27;90(12):5847. doi: 10.1128/JVI.00633-16. Print 2016 Jun 15. No abstract available.

50.

O-Linked N-Acetylglucosamine (O-GlcNAc) Transferase and O-GlcNAcase Interact with Mi2β Protein at the Aγ-Globin Promoter.

Zhang Z, Costa FC, Tan EP, Bushue N, DiTacchio L, Costello CE, McComb ME, Whelan SA, Peterson KR, Slawson C.

J Biol Chem. 2016 Jul 22;291(30):15628-40. doi: 10.1074/jbc.M116.721928. Epub 2016 May 26.

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