Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 17

1.

Discovery of a lead series of potent benzodiazepine 5-HT2C receptor agonists with high selectivity in functional and binding assays.

Ren A, Zhu X, Feichtinger K, Lehman J, Kasem M, Schrader TO, Wong A, Dang H, Le M, Frazer J, Unett DJ, Grottick AJ, Whelan KT, Morgan ME, Sage CR, Semple G.

Bioorg Med Chem Lett. 2020 Mar 1;30(5):126929. doi: 10.1016/j.bmcl.2019.126929. Epub 2019 Dec 26.

PMID:
31952960
2.

Tetrahydroquinoline-based tricyclic amines as potent and selective agonists of the 5-HT2C receptor.

Schrader TO, Kasem M, Ren A, Feichtinger K, Al Doori B, Wei J, Wu C, Dang H, Le M, Gatlin J, Chase K, Dong J, Whelan KT, Sage C, Grottick AJ, Semple G.

Bioorg Med Chem Lett. 2016 Dec 15;26(24):5877-5882. doi: 10.1016/j.bmcl.2016.11.016. Epub 2016 Nov 9.

PMID:
27864071
3.

Pediatric Withdrawal Identification and Management.

Whelan KT, Heckmann MK, Lincoln PA, Hamilton SM.

J Pediatr Intensive Care. 2015 Jun;4(2):73-78. doi: 10.1055/s-0035-1556749. Review.

4.

Safety and immunogenicity of boosting BCG vaccinated subjects with BCG: comparison with boosting with a new TB vaccine, MVA85A.

Whelan KT, Pathan AA, Sander CR, Fletcher HA, Poulton I, Alder NC, Hill AV, McShane H.

PLoS One. 2009 Jun 16;4(6):e5934. doi: 10.1371/journal.pone.0005934. Erratum in: PLoS One. 2011;6(2).doi:10.1371/annotation/ec8cc565-bf24-4898-b7ba-6e0423d5809f.

5.

A comparison of IFNgamma detection methods used in tuberculosis vaccine trials.

Beveridge NE, Fletcher HA, Hughes J, Pathan AA, Scriba TJ, Minassian A, Sander CR, Whelan KT, Dockrell HM, Hill AV, Hanekom WA, McShane H.

Tuberculosis (Edinb). 2008 Nov;88(6):631-40. doi: 10.1016/j.tube.2008.06.005. Epub 2008 Sep 17.

PMID:
18801705
6.

Boosting BCG vaccination with MVA85A down-regulates the immunoregulatory cytokine TGF-beta1.

Fletcher HA, Pathan AA, Berthoud TK, Dunachie SJ, Whelan KT, Alder NC, Sander CR, Hill AV, McShane H.

Vaccine. 2008 Sep 26;26(41):5269-75. doi: 10.1016/j.vaccine.2008.07.040. Epub 2008 Aug 3.

7.

Discovery and structure-activity relationship of (1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine (Lorcaserin), a selective serotonin 5-HT2C receptor agonist for the treatment of obesity.

Smith BM, Smith JM, Tsai JH, Schultz JA, Gilson CA, Estrada SA, Chen RR, Park DM, Prieto EB, Gallardo CS, Sengupta D, Dosa PI, Covel JA, Ren A, Webb RR, Beeley NR, Martin M, Morgan M, Espitia S, Saldana HR, Bjenning C, Whelan KT, Grottick AJ, Menzaghi F, Thomsen WJ.

J Med Chem. 2008 Jan 24;51(2):305-13. Epub 2007 Dec 21.

PMID:
18095642
8.

Boosting BCG with recombinant modified vaccinia ankara expressing antigen 85A: different boosting intervals and implications for efficacy trials.

Pathan AA, Sander CR, Fletcher HA, Poulton I, Alder NC, Beveridge NE, Whelan KT, Hill AV, McShane H.

PLoS One. 2007 Oct 24;2(10):e1052. Erratum in: PLoS One. 2011;6(2).doi:10.1371/annotation/71208a01-eb32-469c-96ab-8d5e3c497fce.

9.

Discovery and SAR of new benzazepines as potent and selective 5-HT(2C) receptor agonists for the treatment of obesity.

Smith BM, Smith JM, Tsai JH, Schultz JA, Gilson CA, Estrada SA, Chen RR, Park DM, Prieto EB, Gallardo CS, Sengupta D, Thomsen WJ, Saldana HR, Whelan KT, Menzaghi F, Webb RR, Beeley NR.

Bioorg Med Chem Lett. 2005 Mar 1;15(5):1467-70.

PMID:
15713408
10.

Pharmacological characterization of SIB-1663, a conformationally rigid analog of nicotine.

Rao TS, Sacaan AI, Menzaghi FM, Reid RT, Adams PB, Correa LD, Whelan KT, Vernier JM.

Brain Res. 2004 Apr 2;1003(1-2):42-53.

PMID:
15019562
11.

The HIV protease inhibitor indinavir reduces immature dendritic cell transendothelial migration.

Whelan KT, Lin CL, Cella M, McMichael AJ, Austyn JM, Rowland-Jones SL.

Eur J Immunol. 2003 Sep;33(9):2520-30.

12.
14.

Macrophage-tropic HIV induces and exploits dendritic cell chemotaxis.

Lin CL, Sewell AK, Gao GF, Whelan KT, Phillips RE, Austyn JM.

J Exp Med. 2000 Aug 21;192(4):587-94.

15.

Interactions between a novel cholinergic ion channel agonist, SIB-1765F and L-DOPA in the reserpine model of Parkinson's disease in rats.

Menzaghi F, Whelan KT, Risbrough VB, Rao TS, Lloyd GK.

J Pharmacol Exp Ther. 1997 Jan;280(1):393-401.

PMID:
8996220
16.

Effects of a novel cholinergic ion channel agonist SIB-1765F on locomotor activity in rats.

Menzaghi F, Whelan KT, Risbrough VB, Rao TS, Lloyd GK.

J Pharmacol Exp Ther. 1997 Jan;280(1):384-92.

PMID:
8996219
17.

Epibatidine: a nicotinic acetylcholine receptor agonist releases monoaminergic neurotransmitters: in vitro and in vivo evidence in rats.

Sacaan AI, Menzaghi F, Dunlop JL, Correa LD, Whelan KT, Lloyd GK.

J Pharmacol Exp Ther. 1996 Feb;276(2):509-15.

PMID:
8632316

Supplemental Content

Loading ...
Support Center