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Items: 1 to 50 of 282

1.

Unbiased data analytic strategies to improve biomarker discovery in precision medicine.

Khan SR, Manialawy Y, Wheeler MB, Cox BJ.

Drug Discov Today. 2019 May 31. pii: S1359-6446(19)30023-6. doi: 10.1016/j.drudis.2019.05.018. [Epub ahead of print] Review.

PMID:
31158511
2.

Shape-fitting collagen-PLA composite promotes osteogenic differentiation of porcine adipose stem cells.

Dewey MJ, Johnson EM, Weisgerber DW, Wheeler MB, Harley BAC.

J Mech Behav Biomed Mater. 2019 Jul;95:21-33. doi: 10.1016/j.jmbbm.2019.03.017. Epub 2019 Mar 22.

PMID:
30953806
3.

Pharmacologic or genetic activation of SIRT1 attenuates the fat-induced decrease in beta-cell function in vivo.

Desai T, Koulajian K, Ivovic A, Breen DM, Luu L, Tsiani EL, Wheeler MB, Giacca A.

Nutr Diabetes. 2019 Mar 19;9(1):11. doi: 10.1038/s41387-019-0075-z.

4.

Non-invasive nuclear magnetic resonance analysis of male and female embryo metabolites during in vitro embryo culture.

Rubessa M, Ambrosi A, Gonzalez-Pena D, Polkoff KM, Wheeler MB.

Metabolomics. 2018 Aug 25;14(9):113. doi: 10.1007/s11306-018-1414-0.

PMID:
30830365
5.

Correction to: The discovery of novel predictive biomarkers and early-stage pathophysiology for the transition from gestational diabetes to type 2 diabetes.

Khan SR, Mohan H, Liu Y, Batchuluun B, Gohil H, Al Rijjal D, Manialawy Y, Cox BJ, Gunderson EP, Wheeler MB.

Diabetologia. 2019 Apr;62(4):730-731. doi: 10.1007/s00125-019-4827-z.

PMID:
30734838
6.

The discovery of novel predictive biomarkers and early-stage pathophysiology for the transition from gestational diabetes to type 2 diabetes.

Khan SR, Mohan H, Liu Y, Batchuluun B, Gohil H, Al Rijjal D, Manialawy Y, Cox BJ, Gunderson EP, Wheeler MB.

Diabetologia. 2019 Apr;62(4):687-703. doi: 10.1007/s00125-018-4800-2. Epub 2019 Jan 15. Erratum in: Diabetologia. 2019 Feb 8;:.

PMID:
30645667
7.

SLIM microscopy allows for visualization of DNA-containing liposomes designed for sperm-mediated gene transfer in cattle.

Rubessa M, Lotti SN, Kandel ME, Popescu G, Wheeler MB.

Mol Biol Rep. 2019 Feb;46(1):695-703. doi: 10.1007/s11033-018-4525-9. Epub 2018 Dec 11.

PMID:
30539382
8.

GABA promotes β-cell proliferation, but does not overcome impaired glucose homeostasis associated with diet-induced obesity.

Untereiner A, Abdo S, Bhattacharjee A, Gohil H, Pourasgari F, Ibeh N, Lai M, Batchuluun B, Wong A, Khuu N, Liu Y, Al Rijjal D, Winegarden N, Virtanen C, Orser BA, Cabrera O, Varga G, Rocheleau J, Dai FF, Wheeler MB.

FASEB J. 2019 Mar;33(3):3968-3984. doi: 10.1096/fj.201801397R. Epub 2018 Dec 3.

PMID:
30509117
9.

Cilostamide affects in a concentration and exposure time-dependent manner the viability and the kinetics of in vitro maturation of caprine and bovine oocytes.

Correia HHV, Vieira LA, Mielgo CM, Paes VM, Alves BG, Silva JRV, Wheeler MB, Rodrigues APR, Figueiredo JR.

Res Vet Sci. 2019 Feb;122:22-28. doi: 10.1016/j.rvsc.2018.11.002. Epub 2018 Nov 12.

PMID:
30448391
10.

3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid (CMPF) prevents high fat diet-induced insulin resistance via maintenance of hepatic lipid homeostasis.

Mohan H, Brandt SL, Kim JH, Wong F, Lai M, Prentice KJ, Al Rijjal D, Magomedova L, Batchuluun B, Burdett E, Bhattacharjee A, Cummins CL, Belsham DD, Cox B, Liu Y, Wheeler MB.

Diabetes Obes Metab. 2019 Jan;21(1):61-72. doi: 10.1111/dom.13483. Epub 2018 Sep 6.

PMID:
30062833
11.

Glucolipotoxic conditions induce β-cell iron import, cytosolic ROS formation and apoptosis.

Hansen JB, Dos Santos LRB, Liu Y, Prentice KJ, Teudt F, Tonnesen M, Jonas JC, Wheeler MB, Mandrup-Poulsen T.

J Mol Endocrinol. 2018 Aug;61(2):69-77. doi: 10.1530/JME-17-0262.

PMID:
30030388
12.

Co-culture of adipose-derived stem cells and chondrocytes on three-dimensionally printed bioscaffolds for craniofacial cartilage engineering.

Morrison RJ, Nasser HB, Kashlan KN, Zopf DA, Milner DJ, Flanangan CL, Wheeler MB, Green GE, Hollister SJ.

Laryngoscope. 2018 Jul;128(7):E251-E257. doi: 10.1002/lary.27200. Epub 2018 Apr 18.

13.

Topography and refractometry of sperm cells using spatial light interference microscopy.

Liu L, Kandel ME, Rubessa M, Schreiber S, Wheeler MB, Popescu G.

J Biomed Opt. 2018 Feb;23(2):1-6. doi: 10.1117/1.JBO.23.2.025003.

PMID:
29488366
14.

Elevated Medium-Chain Acylcarnitines Are Associated With Gestational Diabetes Mellitus and Early Progression to Type 2 Diabetes and Induce Pancreatic β-Cell Dysfunction.

Batchuluun B, Al Rijjal D, Prentice KJ, Eversley JA, Burdett E, Mohan H, Bhattacharjee A, Gunderson EP, Liu Y, Wheeler MB.

Diabetes. 2018 May;67(5):885-897. doi: 10.2337/db17-1150. Epub 2018 Feb 7.

15.

Holo-lipocalin-2-derived siderophores increase mitochondrial ROS and impair oxidative phosphorylation in rat cardiomyocytes.

Song E, Ramos SV, Huang X, Liu Y, Botta A, Sung HK, Turnbull PC, Wheeler MB, Berger T, Wilson DJ, Perry CGR, Mak TW, Sweeney G.

Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):1576-1581. doi: 10.1073/pnas.1720570115. Epub 2018 Jan 29.

16.

Myogenic potential of mesenchymal stem cells isolated from porcine adipose tissue.

Milner DJ, Bionaz M, Monaco E, Cameron JA, Wheeler MB.

Cell Tissue Res. 2018 Jun;372(3):507-522. doi: 10.1007/s00441-017-2764-z. Epub 2018 Jan 9.

PMID:
29318389
17.

CMPF, a Metabolite Formed Upon Prescription Omega-3-Acid Ethyl Ester Supplementation, Prevents and Reverses Steatosis.

Prentice KJ, Wendell SG, Liu Y, Eversley JA, Salvatore SR, Mohan H, Brandt SL, Adams AC, Serena Wang X, Wei D, FitzGerald GA, Durham TB, Hammond CD, Sloop KW, Skarke C, Schopfer FJ, Wheeler MB.

EBioMedicine. 2018 Jan;27:200-213. doi: 10.1016/j.ebiom.2017.12.019. Epub 2017 Dec 19.

18.

A Mineralized Collagen-Polycaprolactone Composite Promotes Healing of a Porcine Mandibular Defect.

Weisgerber DW, Milner DJ, Lopez-Lake H, Rubessa M, Lotti S, Polkoff K, Hortensius RA, Flanagan CL, Hollister SJ, Wheeler MB, Harley BAC.

Tissue Eng Part A. 2018 Jun;24(11-12):943-954. doi: 10.1089/ten.TEA.2017.0293. Epub 2018 Feb 1.

PMID:
29264958
19.

Relationship between follicular dynamics and oocyte maturation during in vitro culture as a non-invasive sign of caprine oocyte meiotic competence.

Cadenas J, Maside C, Ferreira ACA, Vieira LA, Leiva-Revilla J, Paes VM, Alves BG, Brandão FZ, Rodrigues APR, Wheeler MB, Figueiredo JR.

Theriogenology. 2018 Feb;107:95-103. doi: 10.1016/j.theriogenology.2017.10.038. Epub 2017 Nov 4.

PMID:
29145066
20.

Gradient light interference microscopy for 3D imaging of unlabeled specimens.

Nguyen TH, Kandel ME, Rubessa M, Wheeler MB, Popescu G.

Nat Commun. 2017 Aug 8;8(1):210. doi: 10.1038/s41467-017-00190-7.

21.

IKKβ inhibition prevents fat-induced beta cell dysfunction in vitro and in vivo in rodents.

Ivovic A, Oprescu AI, Koulajian K, Mori Y, Eversley JA, Zhang L, Nino-Fong R, Lewis GF, Donath MY, Karin M, Wheeler MB, Ehses J, Volchuk A, Chan CB, Giacca A.

Diabetologia. 2017 Oct;60(10):2021-2032. doi: 10.1007/s00125-017-4345-9. Epub 2017 Jul 20.

PMID:
28725915
22.

Uncoupling protein 2 regulates daily rhythms of insulin secretion capacity in MIN6 cells and isolated islets from male mice.

Seshadri N, Jonasson ME, Hunt KL, Xiang B, Cooper S, Wheeler MB, Dolinsky VW, Doucette CA.

Mol Metab. 2017 Apr 27;6(7):760-769. doi: 10.1016/j.molmet.2017.04.008. eCollection 2017 Jul.

23.

High diluted and dynamised follicle stimulating hormone modulates steroid production in isolated porcine preantral follicles cultured in vitro.

de Lima LF, Rubessa M, Rocha RMP, Winters R, Milner DJ, Campello CC, Figueiredo JR, Wheeler MB.

Homeopathy. 2017 May;106(2):87-92. doi: 10.1016/j.homp.2017.03.004. Epub 2017 Apr 18.

PMID:
28552178
24.

Integration of microfluidics in animal in vitro embryo production.

Wheeler MB, Rubessa M.

Mol Hum Reprod. 2017 Apr 1;23(4):269. doi: 10.1093/molehr/gax009. No abstract available.

PMID:
28369598
25.

Use of Pig as a Model for Mesenchymal Stem Cell Therapies for Bone Regeneration.

Rubessa M, Polkoff K, Bionaz M, Monaco E, Milner DJ, Holllister SJ, Goldwasser MS, Wheeler MB.

Anim Biotechnol. 2017 Oct 2;28(4):275-287. doi: 10.1080/10495398.2017.1279169. Epub 2017 Mar 7.

PMID:
28267421
26.

Synthesis and Characterization of Urofuranoic Acids: In Vivo Metabolism of 2-(2-Carboxyethyl)-4-methyl-5-propylfuran-3-carboxylic Acid (CMPF) and Effects on in Vitro Insulin Secretion.

Nagy E, Liu Y, Prentice KJ, Sloop KW, Sanders PE, Batchuluun B, Hammond CD, Wheeler MB, Durham TB.

J Med Chem. 2017 Mar 9;60(5):1860-1875. doi: 10.1021/acs.jmedchem.6b01668. Epub 2017 Feb 27.

PMID:
28171722
27.

In vitro growth and maturation of isolated caprine preantral follicles: Influence of insulin and FSH concentration, culture dish, coculture, and oocyte size on meiotic resumption.

Silva GM, Brito IR, Sales AD, Aguiar FLN, Duarte ABG, Araújo VR, Vieira LA, Magalhães-Padilha DM, Lima LF, Alves BG, Silveira LBR, Lo Turco EG, Rodrigues AP, Campello CC, Wheeler MB, Figueiredo JR.

Theriogenology. 2017 Mar 1;90:32-41. doi: 10.1016/j.theriogenology.2016.10.026. Epub 2016 Nov 9.

PMID:
28166985
28.

Modification of the Genome of Domestic Animals.

Lotti SN, Polkoff KM, Rubessa M, Wheeler MB.

Anim Biotechnol. 2017 Jul 3;28(3):198-210. doi: 10.1080/10495398.2016.1261874. Epub 2017 Jan 19.

PMID:
28103141
29.

Unexpected effect of the vehicle (grain ethanol) of homeopathic FSH on the in vitro survival and development of isolated ovine preantral follicles.

Lima LF, Rocha RM, Duarte AB, Brito IR, Silva GM, Rodrigues GQ, Nunes-Pinheiro DC, Sales AD, Moura AA, Wheeler MB, Rodrigues AP, Campello CC, Figueiredo JR.

Microsc Res Tech. 2017 Apr;80(4):406-418. doi: 10.1002/jemt.22810. Epub 2016 Dec 5.

PMID:
27921341
30.

High fat induces acute and chronic inflammation in the hypothalamus: effect of high-fat diet, palmitate and TNF-α on appetite-regulating NPY neurons.

Dalvi PS, Chalmers JA, Luo V, Han DY, Wellhauser L, Liu Y, Tran DQ, Castel J, Luquet S, Wheeler MB, Belsham DD.

Int J Obes (Lond). 2017 Jan;41(1):149-158. doi: 10.1038/ijo.2016.183. Epub 2016 Oct 24.

PMID:
27773938
31.

An Abbreviated Protocol for In Vitro Generation of Functional Human Embryonic Stem Cell-Derived Beta-Like Cells.

Massumi M, Pourasgari F, Nalla A, Batchuluun B, Nagy K, Neely E, Gull R, Nagy A, Wheeler MB.

PLoS One. 2016 Oct 18;11(10):e0164457. doi: 10.1371/journal.pone.0164457. eCollection 2016.

32.

Integrating Image-Based Design and 3D Biomaterial Printing to create Patient Specific Devices within a Design Control Framework for Clinical Translation.

Hollister SJ, Flanagan CL, Morrison RJ, Patel JJ, Wheeler MB, Edwards SP, Green GE.

ACS Biomater Sci Eng. 2016 Oct 10;2(10):1827-1836. doi: 10.1021/acsbiomaterials.6b00332. Epub 2016 Sep 12.

33.

Integration of microfluidics in animal in vitro embryo production.

Wheeler MB, Rubessa M.

Mol Hum Reprod. 2017 Apr 1;23(4):248-256. doi: 10.1093/molehr/gaw048. Review. Erratum in: Mol Hum Reprod. 2017 Apr 1;23(4):269.

PMID:
27418669
34.

A Predictive Metabolic Signature for the Transition From Gestational Diabetes Mellitus to Type 2 Diabetes.

Allalou A, Nalla A, Prentice KJ, Liu Y, Zhang M, Dai FF, Ning X, Osborne LR, Cox BJ, Gunderson EP, Wheeler MB.

Diabetes. 2016 Sep;65(9):2529-39. doi: 10.2337/db15-1720. Epub 2016 Jun 23.

35.

Transgenic bovine as bioreactors: Challenges and perspectives.

Monzani PS, Adona PR, Ohashi OM, Meirelles FV, Wheeler MB.

Bioengineered. 2016 Apr;7(3):123-31. doi: 10.1080/21655979.2016.1171429. Epub 2016 May 11. Review.

36.

Anti-Müllerian hormone reduces growth rate without altering follicular survival in isolated caprine preantral follicles cultured in vitro.

Rocha RMP, Lima LF, Brito IR, Silva GM, Correia HHV, Ribeiro de Sá NA, Ferreira ACA, Sales AD, Lobo CH, Campello CC, Smitz J, Wheeler MB, Figueiredo JR.

Reprod Fertil Dev. 2017 Jun;29(6):1144-1154. doi: 10.1071/RD15290.

PMID:
27166082
37.

Rapid Elevation in CMPF May Act As a Tipping Point in Diabetes Development.

Liu Y, Prentice KJ, Eversley JA, Hu C, Batchuluun B, Leavey K, Hansen JB, Wei DW, Cox B, Dai FF, Jia W, Wheeler MB.

Cell Rep. 2016 Mar 29;14(12):2889-900. doi: 10.1016/j.celrep.2016.02.079. Epub 2016 Mar 17.

38.

Deletion of ARNT/HIF1β in pancreatic beta cells does not impair glucose homeostasis in mice, but is associated with defective glucose sensing ex vivo.

Pillai R, Paglialunga S, Hoang M, Cousteils K, Prentice KJ, Bombardier E, Huang M, Gonzalez FJ, Tupling AR, Wheeler MB, Joseph JW.

Diabetologia. 2015 Dec;58(12):2832-42. doi: 10.1007/s00125-015-3768-4. Epub 2015 Sep 26.

39.
40.

A Novel GLP1 Receptor Interacting Protein ATP6ap2 Regulates Insulin Secretion in Pancreatic Beta Cells.

Dai FF, Bhattacharjee A, Liu Y, Batchuluun B, Zhang M, Wang XS, Huang X, Luu L, Zhu D, Gaisano H, Wheeler MB.

J Biol Chem. 2015 Oct 9;290(41):25045-61. doi: 10.1074/jbc.M115.648592. Epub 2015 Aug 13.

41.

Correction: A Novel Humanized GLP-1 Receptor Model Enables Both Affinity Purification and Cre-LoxP Deletion of the Receptor.

Jun LS, Showalter AD, Ali N, Dai F, Ma W, Coskun T, Ficorilli JV, Wheeler MB, Michael MD, Sloop KW.

PLoS One. 2015 Jul 14;10(7):e0132875. doi: 10.1371/journal.pone.0132875. eCollection 2015. No abstract available.

42.

Islet amyloid inhibitors improve glucose homeostasis in a transgenic mouse model of type 2 diabetes.

Wijesekara N, Ahrens R, Wu L, Ha K, Liu Y, Wheeler MB, Fraser PE.

Diabetes Obes Metab. 2015 Oct;17(10):1003-6. doi: 10.1111/dom.12529. Epub 2015 Aug 19.

PMID:
26095311
43.

The Identification of Novel Protein-Protein Interactions in Liver that Affect Glucagon Receptor Activity.

Han J, Zhang M, Froese S, Dai FF, Robitaille M, Bhattacharjee A, Huang X, Jia W, Angers S, Wheeler MB, Wei L.

PLoS One. 2015 Jun 15;10(6):e0129226. doi: 10.1371/journal.pone.0129226. eCollection 2015.

44.

INVITED REVIEW: Evolution of meat animal growth research during the past 50 years: Adipose and muscle stem cells.

Dodson MV, Allen RE, Du M, Bergen WG, Velleman SG, Poulos SP, Fernyhough-Culver M, Wheeler MB, Duckett SK, Young MR, Voy BH, Jiang Z, Hausman GJ.

J Anim Sci. 2015 Feb;93(2):457-81. doi: 10.2527/jas.2014-8221. Review.

PMID:
26020737
45.

Rhabdomyolysis precipitated by possible interaction of ticagrelor with high-dose atorvastatin.

Kido K, Wheeler MB, Seratnahaei A, Bailey A, Bain JA.

J Am Pharm Assoc (2003). 2015 May-Jun;55(3):320-3. doi: 10.1331/JAPhA.2015.14151.

PMID:
26003161
46.

Characterization of Zinc Influx Transporters (ZIPs) in Pancreatic β Cells: ROLES IN REGULATING CYTOSOLIC ZINC HOMEOSTASIS AND INSULIN SECRETION.

Liu Y, Batchuluun B, Ho L, Zhu D, Prentice KJ, Bhattacharjee A, Zhang M, Pourasgari F, Hardy AB, Taylor KM, Gaisano H, Dai FF, Wheeler MB.

J Biol Chem. 2015 Jul 24;290(30):18757-69. doi: 10.1074/jbc.M115.640524. Epub 2015 May 12.

47.

LKB1 couples glucose metabolism to insulin secretion in mice.

Fu A, Robitaille K, Faubert B, Reeks C, Dai XQ, Hardy AB, Sankar KS, Ogrel S, Al-Dirbashi OY, Rocheleau JV, Wheeler MB, MacDonald PE, Jones R, Screaton RA.

Diabetologia. 2015 Jul;58(7):1513-22. doi: 10.1007/s00125-015-3579-7. Epub 2015 Apr 16.

PMID:
25874445
48.

Zip4 mediated zinc influx stimulates insulin secretion in pancreatic beta cells.

Hardy AB, Prentice KJ, Froese S, Liu Y, Andrews GK, Wheeler MB.

PLoS One. 2015 Mar 25;10(3):e0119136. doi: 10.1371/journal.pone.0119136. eCollection 2015.

49.

Ambient ionisation mass spectrometry for lipid profiling and structural analysis of mammalian oocytes, preimplantation embryos and stem cells.

Ferreira CR, Jarmusch AK, Pirro V, Alfaro CM, González-Serrano AF, Niemann H, Wheeler MB, Rabel RA, Hallett JE, Houser R, Kaufman A, Cooks RG.

Reprod Fertil Dev. 2015 May;27(4):621-37. doi: 10.1071/RD14310. Review.

PMID:
25763644
50.

FFAR out new targets for diabetes.

Prentice KJ, Wheeler MB.

Cell Metab. 2015 Mar 3;21(3):353-4. doi: 10.1016/j.cmet.2015.02.015.

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