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Photosynthetic responses of turf-forming red macroalgae to high-CO2 conditions.

McCoy SJ, Santillán-Sarmiento A, Brown MT, Widdicombe S, Wheeler GL.

J Phycol. 2019 Sep 25. doi: 10.1111/jpy.12922. [Epub ahead of print]


Microsyntenic Clusters Reveal Conservation of lncRNAs in Chordates Despite Absence of Sequence Conservation.

Herrera-Úbeda C, Marín-Barba M, Navas-Pérez E, Gravemeyer J, Albuixech-Crespo B, Wheeler GN, Garcia-Fernàndez J.

Biology (Basel). 2019 Aug 24;8(3). pii: E61. doi: 10.3390/biology8030061.


A Retrospective Evaluation of Risk of Peripartum Cardiac Dysfunction in Survivors of Childhood, Adolescent and Young Adult Malignancies.

Chait-Rubinek L, Mariani JA, Goroncy N, Herschtal A, Wheeler GC, Dwyer MK, Seymour JF, Campbell BA.

Cancers (Basel). 2019 Jul 24;11(8). pii: E1046. doi: 10.3390/cancers11081046.


Assembling the brain trust: the multidisciplinary imperative in neuro-oncology.

Ludmir EB, Mahajan A, Ahern V, Ajithkumar T, Alapetite C, Bernier-Chastagner V, Bindra RS, Bishop AJ, Bolle S, Brown PD, Carrie C, Chalmers AJ, Chang EL, Chung C, Dieckmann K, Esiashvili N, Gandola L, Ghia AJ, Gondi V, Grosshans DR, Harrabi SB, Horan G, Indelicato DJ, Jalali R, Janssens GO, Krause M, Laack NN, Laperriere N, Laprie A, Li J, Marcus KJ, McGovern SL, Merchant TE, Merrell KW, Padovani L, Parkes J, Paulino AC, Schwarz R, Shih HA, Souhami L, Sulman EP, Taylor RE, Thorp N, Timmermann B, Wheeler G, Wolden SL, Woodhouse KD, Yeboa DN, Yock TI, Kortmann RD, McAleer MF.

Nat Rev Clin Oncol. 2019 Aug;16(8):521-522. doi: 10.1038/s41571-019-0235-z. No abstract available.


A Review of Chronic Leukoencephalopathy among Survivors of Childhood Cancer.

Partap S, Russo S, Esfahani B, Yeom K, Mazewski C, Embry L, Wheeler G, Ullrich NJ, Bowers DC.

Pediatr Neurol. 2019 Mar 21. pii: S0887-8994(18)31330-4. doi: 10.1016/j.pediatrneurol.2019.03.006. [Epub ahead of print] Review.


Alternative Mechanisms for Fast Na+/Ca2+ Signaling in Eukaryotes via a Novel Class of Single-Domain Voltage-Gated Channels.

Helliwell KE, Chrachri A, Koester JA, Wharam S, Verret F, Taylor AR, Wheeler GL, Brownlee C.

Curr Biol. 2019 May 6;29(9):1503-1511.e6. doi: 10.1016/j.cub.2019.03.041. Epub 2019 Apr 18.


A Bayesian model-free approach to combination therapy phase I trials using censored time-to-toxicity data.

Wheeler GM, Sweeting MJ, Mander AP.

J R Stat Soc Ser C Appl Stat. 2019 Feb;68(2):309-329. doi: 10.1111/rssc.12323. Epub 2018 Nov 22.


Virtual interaction and visualisation of 3D medical imaging data with VTK and Unity.

Wheeler G, Deng S, Toussaint N, Pushparajah K, Schnabel JA, Simpson JM, Gomez A.

Healthc Technol Lett. 2018 Sep 21;5(5):148-153. doi: 10.1049/htl.2018.5064. eCollection 2018 Oct.


Stereotactic ablative radiotherapy versus standard radiotherapy in stage 1 non-small-cell lung cancer (TROG 09.02 CHISEL): a phase 3, open-label, randomised controlled trial.

Ball D, Mai GT, Vinod S, Babington S, Ruben J, Kron T, Chesson B, Herschtal A, Vanevski M, Rezo A, Elder C, Skala M, Wirth A, Wheeler G, Lim A, Shaw M, Schofield P, Irving L, Solomon B; TROG 09.02 CHISEL investigators.

Lancet Oncol. 2019 Apr;20(4):494-503. doi: 10.1016/S1470-2045(18)30896-9. Epub 2019 Feb 12.


How to design a dose-finding study using the continual reassessment method.

Wheeler GM, Mander AP, Bedding A, Brock K, Cornelius V, Grieve AP, Jaki T, Love SB, Odondi L, Weir CJ, Yap C, Bond SJ.

BMC Med Res Methodol. 2019 Jan 18;19(1):18. doi: 10.1186/s12874-018-0638-z.


Correction: The anti-rheumatic drug, leflunomide, synergizes with MEK inhibition to suppress melanoma growth.

Hanson K, Robinson SD, Al-Yousuf K, Hendry AE, Sexton DW, Sherwood V, Wheeler GN.

Oncotarget. 2018 Nov 27;9(93):36645. doi: 10.18632/oncotarget.26415. eCollection 2018 Nov 27.


A Comparison of Structured Education Programs for Pediatric Patients With Type 1 Diabetes: Multiple Daily Injection Therapy Delivered by Group Workshop vs. Self-Study Course.

Johnston K, Wheeler G, Rosolowsky E.

Can J Diabetes. 2019 Jun;43(4):290-293. doi: 10.1016/j.jcjd.2018.08.060. Epub 2018 Aug 9. No abstract available.


Solid lipid nanoparticles for the delivery of anti-microbial oligonucleotides.

González-Paredes A, Sitia L, Ruyra A, Morris CJ, Wheeler GN, McArthur M, Gasco P.

Eur J Pharm Biopharm. 2019 Jan;134:166-177. doi: 10.1016/j.ejpb.2018.11.017. Epub 2018 Nov 20.


Paracetamol-induced liver injury modelled in Xenopus laevis embryos.

Saide K, Sherwood V, Wheeler GN.

Toxicol Lett. 2019 Mar 1;302:83-91. doi: 10.1016/j.toxlet.2018.09.016. Epub 2018 Sep 30.


Toxic Peptides in Populations of Two Pergid Sawflies, Potential Biocontrol Agents of Brazilian Peppertree.

Boevé JL, Rozenberg R, Mc Kay F, Wheeler GS.

J Chem Ecol. 2018 Dec;44(12):1139-1145. doi: 10.1007/s10886-018-1021-6. Epub 2018 Oct 1.


A technique for total skin electron therapy (TSET) of an anesthetized pediatric patient.

Kron T, Donahoo G, Lonski P, Wheeler G.

J Appl Clin Med Phys. 2018 Nov;19(6):109-116. doi: 10.1002/acm2.12457. Epub 2018 Sep 29.


Cross-exchange of B-vitamins underpins a mutualistic interaction between Ostreococcus tauri and Dinoroseobacter shibae.

Cooper MB, Kazamia E, Helliwell KE, Kudahl UJ, Sayer A, Wheeler GL, Smith AG.

ISME J. 2019 Feb;13(2):334-345. doi: 10.1038/s41396-018-0274-y. Epub 2018 Sep 18.


ADAMTS9, a member of the ADAMTS family, in Xenopus development.

Desanlis I, Felstead HL, Edwards DR, Wheeler GN.

Gene Expr Patterns. 2018 Sep;29:72-81. doi: 10.1016/j.gep.2018.06.001. Epub 2018 Jun 21.


The requirement for calcification differs between ecologically important coccolithophore species.

Walker CE, Taylor AR, Langer G, Durak GM, Heath S, Probert I, Tyrrell T, Brownlee C, Wheeler GL.

New Phytol. 2018 Oct;220(1):147-162. doi: 10.1111/nph.15272. Epub 2018 Jun 19.


Incoherent dose-escalation in phase I trials using the escalation with overdose control approach.

Wheeler GM.

Stat Pap (Berl). 2018 Jun;59(2):801-811. doi: 10.1007/s00362-016-0790-7. Epub 2016 Jun 24.


miR-133-mediated regulation of the Hedgehog pathway orchestrates embryo myogenesis.

Mok GF, Lozano-Velasco E, Maniou E, Viaut C, Moxon S, Wheeler G, Münsterberg A.

Development. 2018 Jun 11;145(12). pii: dev159657. doi: 10.1242/dev.159657.


High sensitivity and label-free oligonucleotides detection using photonic bandgap sensing structures biofunctionalized with molecular beacon probes.

Ruiz-Tórtola Á, Prats-Quílez F, González-Lucas D, Bañuls MJ, Maquieira Á, Wheeler G, Dalmay T, Griol A, Hurtado J, García-Rupérez J.

Biomed Opt Express. 2018 Mar 14;9(4):1717-1727. doi: 10.1364/BOE.9.001717. eCollection 2018 Apr 1.


Experimental study of the evanescent-wave photonic sensors response in presence of molecular beacon conformational changes.

Ruiz-Tórtola Á, Prats-Quílez F, González-Lucas D, Bañuls MJ, Maquieira Á, Wheeler G, Dalmay T, Griol A, Hurtado J, Bohlmann H, Götzen R, García-Rupérez J.

J Biophotonics. 2018 Oct;11(10):e201800030. doi: 10.1002/jbio.201800030. Epub 2018 Jun 28.


Adaptive designs in clinical trials: why use them, and how to run and report them.

Pallmann P, Bedding AW, Choodari-Oskooei B, Dimairo M, Flight L, Hampson LV, Holmes J, Mander AP, Odondi L, Sydes MR, Villar SS, Wason JMS, Weir CJ, Wheeler GM, Yap C, Jaki T.

BMC Med. 2018 Feb 28;16(1):29. doi: 10.1186/s12916-018-1017-7.


The anti-rheumatic drug, leflunomide, synergizes with MEK inhibition to suppress melanoma growth.

Hanson K, Robinson SD, Al-Yousuf K, Hendry AE, Sexton DW, Sherwood V, Wheeler GN.

Oncotarget. 2017 Dec 17;9(3):3815-3829. doi: 10.18632/oncotarget.23378. eCollection 2018 Jan 9. Erratum in: Oncotarget. 2018 Nov 27;9(93):36645. Robinson, Stephen R [corrected to Robinson, Stephen D].


Transcriptome profiles of sunflower reveal the potential role of microsatellites in gene expression divergence.

Ranathunge C, Wheeler GL, Chimahusky ME, Kennedy MM, Morrison JI, Baldwin BS, Perkins AD, Welch ME.

Mol Ecol. 2018 Mar;27(5):1188-1199. doi: 10.1111/mec.14522. Epub 2018 Mar 8.


Evaluating the adaptive evolutionary convergence of carnivorous plant taxa through functional genomics.

Wheeler GL, Carstens BC.

PeerJ. 2018 Jan 31;6:e4322. doi: 10.7717/peerj.4322. eCollection 2018.


Surfer's myelopathy: A rare presentation in a teenage gymnast and review of the literature.

Dillen WL, Hendricks BK, Mannas JP, Wheeler GR.

J Clin Neurosci. 2018 Apr;50:157-160. doi: 10.1016/j.jocn.2018.01.039. Epub 2018 Feb 1. Review.


microRNAs associated with early neural crest development in Xenopus laevis.

Ward NJ, Green D, Higgins J, Dalmay T, Münsterberg A, Moxon S, Wheeler GN.

BMC Genomics. 2018 Jan 18;19(1):59. doi: 10.1186/s12864-018-4436-0.


Dynamic changes in carbonate chemistry in the microenvironment around single marine phytoplankton cells.

Chrachri A, Hopkinson BM, Flynn K, Brownlee C, Wheeler GL.

Nat Commun. 2018 Jan 8;9(1):74. doi: 10.1038/s41467-017-02426-y.


Unravelling the mechanisms that determine the uptake and metabolism of magnetic single and multicore nanoparticles in a Xenopus laevis model.

Marín-Barba M, Gavilán H, Gutiérrez L, Lozano-Velasco E, Rodríguez-Ramiro I, Wheeler GN, Morris CJ, Morales MP, Ruiz A.

Nanoscale. 2018 Jan 3;10(2):690-704. doi: 10.1039/c7nr06020c.


Genome-wide dose-dependent inhibition of histone deacetylases studies reveal their roles in enhancer remodeling and suppression of oncogenic super-enhancers.

Sanchez GJ, Richmond PA, Bunker EN, Karman SS, Azofeifa J, Garnett AT, Xu Q, Wheeler GE, Toomey CM, Zhang Q, Dowell RD, Liu X.

Nucleic Acids Res. 2018 Feb 28;46(4):1756-1776. doi: 10.1093/nar/gkx1225.


Single Fraction Stereotactic Ablative Body Radiotherapy for Oligometastasis: Outcomes from 132 Consecutive Patients.

Gandhidasan S, Ball D, Kron T, Bressel M, Shaw M, Chu J, Chander S, Wheeler G, Plumridge N, Chesson B, David S, Siva S.

Clin Oncol (R Coll Radiol). 2018 Mar;30(3):178-184. doi: 10.1016/j.clon.2017.11.010. Epub 2017 Dec 8.


Development of Functional Electrical Stimulation Rowing: The Rowstim Series.

Andrews B, Gibbons R, Wheeler G.

Artif Organs. 2017 Nov;41(11):E203-E212. doi: 10.1111/aor.13053. Review.


The role of the cytoskeleton in biomineralisation in haptophyte algae.

Durak GM, Brownlee C, Wheeler GL.

Sci Rep. 2017 Nov 13;7(1):15409. doi: 10.1038/s41598-017-15562-8.


Frizzled-7 is required for Xenopus heart development.

Abu-Elmagd M, Mulvaney J, Wheeler GN.

Biol Open. 2017 Dec 15;6(12):1861-1868. doi: 10.1242/bio.026963.


Impact of Field Densities of the Naturalized Defoliator Caloptilia triadicae (Lepidoptera: Gracillariidae) on the Invasive Weed Chinese Tallowtree.

Wheeler GS, Hight SD, Wright SA.

Environ Entomol. 2017 Dec 8;46(6):1305-1312. doi: 10.1093/ee/nvx148.


Combining Cytotoxicity Assessment and Xenopus laevis Phenotypic Abnormality Assay as a Predictor of Nanomaterial Safety.

Al-Yousuf K, Webster CA, Wheeler GN, Bombelli FB, Sherwood V.

Curr Protoc Toxicol. 2017 Aug 4;73:20.13.1-20.13.33. doi: 10.1002/cptx.25.


Insights into the red algae and eukaryotic evolution from the genome of Porphyra umbilicalis (Bangiophyceae, Rhodophyta).

Brawley SH, Blouin NA, Ficko-Blean E, Wheeler GL, Lohr M, Goodson HV, Jenkins JW, Blaby-Haas CE, Helliwell KE, Chan CX, Marriage TN, Bhattacharya D, Klein AS, Badis Y, Brodie J, Cao Y, Collén J, Dittami SM, Gachon CMM, Green BR, Karpowicz SJ, Kim JW, Kudahl UJ, Lin S, Michel G, Mittag M, Olson BJSC, Pangilinan JL, Peng Y, Qiu H, Shu S, Singer JT, Smith AG, Sprecher BN, Wagner V, Wang W, Wang ZY, Yan J, Yarish C, Zäuner-Riek S, Zhuang Y, Zou Y, Lindquist EA, Grimwood J, Barry KW, Rokhsar DS, Schmutz J, Stiller JW, Grossman AR, Prochnik SE.

Proc Natl Acad Sci U S A. 2017 Aug 1;114(31):E6361-E6370. doi: 10.1073/pnas.1703088114. Epub 2017 Jul 17.


A functional approach to understanding the role of NCKX5 in Xenopus pigmentation.

Williams RM, Winkfein RJ, Ginger RS, Green MR, Schnetkamp PP, Wheeler GN.

PLoS One. 2017 Jul 10;12(7):e0180465. doi: 10.1371/journal.pone.0180465. eCollection 2017.


Cationic liposomal vectors incorporating a bolaamphiphile for oligonucleotide antimicrobials.

Mamusa M, Sitia L, Barbero F, Ruyra A, Calvo TD, Montis C, Gonzalez-Paredes A, Wheeler GN, Morris CJ, McArthur M, Berti D.

Biochim Biophys Acta Biomembr. 2017 Oct;1859(10):1767-1777. doi: 10.1016/j.bbamem.2017.06.006. Epub 2017 Jun 10.


Phylogeography and genetic structure of endemic Acmispon argophyllus and A. dendroideus (Fabaceae) across the California Channel Islands.

Wallace LE, Wheeler GL, McGlaughlin ME, Bresowar G, Helenurm K.

Am J Bot. 2017 May;104(5):743-756. doi: 10.3732/ajb.1600429. Epub 2017 May 19.


Extended and standard duration weight-loss programme referrals for adults in primary care (WRAP): a randomised controlled trial.

Ahern AL, Wheeler GM, Aveyard P, Boyland EJ, Halford JCG, Mander AP, Woolston J, Thomson AM, Tsiountsioura M, Cole D, Mead BR, Irvine L, Turner D, Suhrcke M, Pimpin L, Retat L, Jaccard A, Webber L, Cohn SR, Jebb SA.

Lancet. 2017 Jun 3;389(10085):2214-2225. doi: 10.1016/S0140-6736(17)30647-5. Epub 2017 May 3. Erratum in: Lancet. 2017 Jun 3;389(10085):2192.


Toxicity-dependent feasibility bounds for the escalation with overdose control approach in phase I cancer trials.

Wheeler GM, Sweeting MJ, Mander AP.

Stat Med. 2017 Jul 20;36(16):2499-2513. doi: 10.1002/sim.7280. Epub 2017 Mar 15.


Coccolithophore Cell Biology: Chalking Up Progress.

Taylor AR, Brownlee C, Wheeler G.

Ann Rev Mar Sci. 2017 Jan 3;9:283-310. doi: 10.1146/annurev-marine-122414-034032. Epub 2016 Oct 28.


The Evolution of Silicon Transport in Eukaryotes.

Marron AO, Ratcliffe S, Wheeler GL, Goldstein RE, King N, Not F, de Vargas C, Richter DJ.

Mol Biol Evol. 2016 Dec;33(12):3226-3248. Epub 2016 Oct 11.


Spatial and temporal specificity of Ca2+ signalling in Chlamydomonas reinhardtii in response to osmotic stress.

Bickerton P, Sello S, Brownlee C, Pittman JK, Wheeler GL.

New Phytol. 2016 Dec;212(4):920-933. doi: 10.1111/nph.14128. Epub 2016 Aug 12.


AplusB: A Web Application for Investigating A + B Designs for Phase I Cancer Clinical Trials.

Wheeler GM, Sweeting MJ, Mander AP.

PLoS One. 2016 Jul 12;11(7):e0159026. doi: 10.1371/journal.pone.0159026. eCollection 2016.


The role of coccolithophore calcification in bioengineering their environment.

Flynn KJ, Clark DR, Wheeler G.

Proc Biol Sci. 2016 Jun 29;283(1833). pii: 20161099. doi: 10.1098/rspb.2016.1099.


Early and Intensive Dietary Counseling in Lung Cancer Patients Receiving (Chemo)Radiotherapy-A Pilot Randomized Controlled Trial.

Kiss N, Isenring E, Gough K, Wheeler G, Wirth A, Campbell BA, Krishnasamy M.

Nutr Cancer. 2016 Aug-Sep;68(6):958-67. doi: 10.1080/01635581.2016.1188972. Epub 2016 Jun 27.


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