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Items: 31


Analytical electrolyzer enabling operando characterization of flow plates.

Wheeler DG, Virca CN, Berlinguette CP.

Rev Sci Instrum. 2019 Jul;90(7):074103. doi: 10.1063/1.5053600.


Preclinical Development of a vWF Aptamer to Limit Thrombosis and Engender Arterial Recanalization of Occluded Vessels.

Nimjee SM, Dornbos D 3rd, Pitoc GA, Wheeler DG, Layzer JM, Venetos N, Huttinger A, Talentino SE, Musgrave NJ, Moody H, Rempel RE, Jones C, Carlisle K, Wilson J, Bratton C, Joseph ME, Khan S, Hoffman MR, Sommerville L, Becker RC, Zweier JL, Sullenger BA.

Mol Ther. 2019 Jul 3;27(7):1228-1241. doi: 10.1016/j.ymthe.2019.03.016. Epub 2019 Mar 30.


Ferric Chloride-induced Canine Carotid Artery Thrombosis: A Large Animal Model of Vascular Injury.

Huttinger AL, Wheeler DG, Gnyawali S, Dornbos D 3rd, Layzer JM, Venetos N, Talentino S, Musgrave NJ, Jones C, Bratton C, Joseph ME, Sen C, Sullenger BA, Nimjee SM.

J Vis Exp. 2018 Sep 7;(139). doi: 10.3791/57981.


PDE4D regulates Spine Plasticity and Memory in the Retrosplenial Cortex.

Baumgärtel K, Green A, Hornberger D, Lapira J, Rex C, Wheeler DG, Peters M.

Sci Rep. 2018 Mar 1;8(1):3895. doi: 10.1038/s41598-018-22193-0.


Kcnj11 Ablation Is Associated With Increased Nitro-Oxidative Stress During Ischemia-Reperfusion Injury: Implications for Human Ischemic Cardiomyopathy.

Zhang B, Novitskaya T, Wheeler DG, Xu Z, Chepurko E, Huttinger R, He H, Varadharaj S, Zweier JL, Song Y, Xu M, Harrell FE Jr, Su YR, Absi T, Kohr MJ, Ziolo MT, Roden DM, Shaffer CM, Galindo CL, Wells QS, Gumina RJ.

Circ Heart Fail. 2017 Feb;10(2). pii: e003523. doi: 10.1161/CIRCHEARTFAILURE.116.003523.


Impact of cardiac-specific expression of CD39 on myocardial infarct size in mice.

Smith SB, Xu Z, Novitskaya T, Zhang B, Chepurko E, Pu XA, Wheeler DG, Ziolo M, Gumina RJ.

Life Sci. 2017 Jun 15;179:54-59. doi: 10.1016/j.lfs.2016.10.016. Epub 2016 Oct 15.


Role of the CD39/CD73 Purinergic Pathway in Modulating Arterial Thrombosis in Mice.

Covarrubias R, Chepurko E, Reynolds A, Huttinger ZM, Huttinger R, Stanfill K, Wheeler DG, Novitskaya T, Robson SC, Dwyer KM, Cowan PJ, Gumina RJ.

Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1809-20. doi: 10.1161/ATVBAHA.116.307374. Epub 2016 Jul 14.


Ca(V)1 and Ca(V)2 channels engage distinct modes of Ca(2+) signaling to control CREB-dependent gene expression.

Wheeler DG, Groth RD, Ma H, Barrett CF, Owen SF, Safa P, Tsien RW.

Cell. 2012 May 25;149(5):1112-24. doi: 10.1016/j.cell.2012.03.041.


Ectonucleotide triphosphate diphosphohydrolase-1 (CD39) mediates resistance to occlusive arterial thrombus formation after vascular injury in mice.

Huttinger ZM, Milks MW, Nickoli MS, Aurand WL, Long LC, Wheeler DG, Dwyer KM, d'Apice AJ, Robson SC, Cowan PJ, Gumina RJ.

Am J Pathol. 2012 Jul;181(1):322-33. doi: 10.1016/j.ajpath.2012.03.024. Epub 2012 May 18.


Transgenic swine: expression of human CD39 protects against myocardial injury.

Wheeler DG, Joseph ME, Mahamud SD, Aurand WL, Mohler PJ, Pompili VJ, Dwyer KM, Nottle MB, Harrison SJ, d'Apice AJ, Robson SC, Cowan PJ, Gumina RJ.

J Mol Cell Cardiol. 2012 May;52(5):958-61. doi: 10.1016/j.yjmcc.2012.01.002. Epub 2012 Jan 12.


Transgenic over expression of ectonucleotide triphosphate diphosphohydrolase-1 protects against murine myocardial ischemic injury.

Cai M, Huttinger ZM, He H, Zhang W, Li F, Goodman LA, Wheeler DG, Druhan LJ, Zweier JL, Dwyer KM, He G, d'Apice AJ, Robson SC, Cowan PJ, Gumina RJ.

J Mol Cell Cardiol. 2011 Dec;51(6):927-35. doi: 10.1016/j.yjmcc.2011.09.003. Epub 2011 Sep 12.


Excitation-transcription coupling in sympathetic neurons and the molecular mechanism of its initiation.

Ma H, Groth RD, Wheeler DG, Barrett CF, Tsien RW.

Neurosci Res. 2011 May;70(1):2-8. doi: 10.1016/j.neures.2011.02.004. Epub 2011 Feb 23. Review.


Antioxidant network expression abrogates oxidative posttranslational modifications in mice.

Mital R, Zhang W, Cai M, Huttinger ZM, Goodman LA, Wheeler DG, Ziolo MT, Dwyer KM, d'Apice AJ, Zweier JL, He G, Cowan PJ, Gumina RJ.

Am J Physiol Heart Circ Physiol. 2011 May;300(5):H1960-70. doi: 10.1152/ajpheart.01285.2010. Epub 2011 Feb 18.


Uncoupling dendrite growth and patterning: single-cell knockout analysis of NMDA receptor 2B.

Espinosa JS, Wheeler DG, Tsien RW, Luo L.

Neuron. 2009 Apr 30;62(2):205-17. doi: 10.1016/j.neuron.2009.03.006.


CaMKII locally encodes L-type channel activity to signal to nuclear CREB in excitation-transcription coupling.

Wheeler DG, Barrett CF, Groth RD, Safa P, Tsien RW.

J Cell Biol. 2008 Dec 1;183(5):849-63. doi: 10.1083/jcb.200805048.


Biphasic effect of SIN-1 is reliant upon cardiomyocyte contractile state.

Kohr MJ, Wang H, Wheeler DG, Velayutham M, Zweier JL, Ziolo MT.

Free Radic Biol Med. 2008 Jul 1;45(1):73-80. doi: 10.1016/j.freeradbiomed.2008.03.019. Epub 2008 Apr 4.


Neuronal nitric oxide synthase signaling within cardiac myocytes targets phospholamban.

Wang H, Kohr MJ, Traynham CJ, Wheeler DG, Janssen PM, Ziolo MT.

Am J Physiol Cell Physiol. 2008 Jun;294(6):C1566-75. doi: 10.1152/ajpcell.00367.2007. Epub 2008 Apr 9.


Endothelial nitric oxide synthase decreases beta-adrenergic responsiveness via inhibition of the L-type Ca2+ current.

Wang H, Kohr MJ, Wheeler DG, Ziolo MT.

Am J Physiol Heart Circ Physiol. 2008 Mar;294(3):H1473-80. doi: 10.1152/ajpheart.01249.2007. Epub 2008 Jan 18.


Targeting of phospholamban by peroxynitrite decreases beta-adrenergic stimulation in cardiomyocytes.

Kohr MJ, Wang H, Wheeler DG, Velayutham M, Zweier JL, Ziolo MT.

Cardiovasc Res. 2008 Jan 15;77(2):353-61. Epub 2007 Sep 19.


Localised reductions in gyrification in the posterior cingulate: schizophrenia and controls.

Wheeler DG, Harper CG.

Prog Neuropsychopharmacol Biol Psychiatry. 2007 Mar 30;31(2):319-27. Epub 2006 Nov 1.


L-type calcium channel ligands block nicotine-induced signaling to CREB by inhibiting nicotinic receptors.

Wheeler DG, Barrett CF, Tsien RW.

Neuropharmacology. 2006 Jul;51(1):27-36. Epub 2006 Apr 24.


No differences in calcium-binding protein immunoreactivity in the posterior cingulate and visual cortex: schizophrenia and controls.

Wheeler DG, Dixon G, Harper CG.

Prog Neuropsychopharmacol Biol Psychiatry. 2006 Jun;30(4):630-9. Epub 2006 Feb 28.


Effect of glutathione augmentation on lipid peroxidation after spinal cord injury.

Lucas JH, Wheeler DG, Guan Z, Suntres Z, Stokes BT.

J Neurotrauma. 2002 Jun;19(6):763-75. Erratum in: J Neurotrauma. 2003 Jan;20(1):121..


Depolarization strongly induces human cytomegalovirus major immediate-early promoter/enhancer activity in neurons.

Wheeler DG, Cooper E.

J Biol Chem. 2001 Aug 24;276(34):31978-85. Epub 2001 Jun 7.


The endogenous antioxidant glutathione as a factor in the survival of physically injured mammalian spinal cord neurons.

Lucas JH, Wheeler DG, Emery DG, Mallery SR.

J Neuropathol Exp Neurol. 1998 Oct;57(10):937-54.


Analysis of molecular mechanisms controlling neuroendocrine cell specific transcription of the chromogranin A gene.

Canaff L, Bevan S, Wheeler DG, Mouland AJ, Rehfuss RP, White JH, Hendy GN.

Endocrinology. 1998 Mar;139(3):1184-96.


Calreticulin inhibits vitamin D3 signal transduction.

Wheeler DG, Horsford J, Michalak M, White JH, Hendy GN.

Nucleic Acids Res. 1995 Aug 25;23(16):3268-74.


Preterm birth prevention.

Wheeler DG.

J Nurse Midwifery. 1994 Mar-Apr;39(2 Suppl):66S-80S. Review.


Intrapartum bleeding.

Wheeler DG.

NAACOGS Clin Issu Perinat Womens Health Nurs. 1991;2(3):381-4.


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