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Items: 1 to 50 of 74

1.

Clinical outcomes associated with the use of the NexSite hemodialysis catheter with new exit barrier technology: Results from a prospective, observational multi-center registry study.

Hoggard JG, Blair RD, Montero M, Moustafa MA, Newman J, Pergola PE, Saucier N, Wheeler CJ 3rd, Mermel LA, Ross JR, Beserab AD.

PLoS One. 2019 Oct 7;14(10):e0223285. doi: 10.1371/journal.pone.0223285. eCollection 2019.

2.

A Simple Three-dimensional Hydrogel Platform Enables Ex Vivo Cell Culture of Patient and PDX Tumors for Assaying Their Response to Clinically Relevant Therapies.

Hribar KC, Wheeler CJ, Bazarov A, Varshneya K, Yamada R, Buckley P, Patil CG.

Mol Cancer Ther. 2019 Mar;18(3):718-725. doi: 10.1158/1535-7163.MCT-18-0359. Epub 2019 Feb 12.

PMID:
30755456
3.

Human Hematopoietic Signal peptide-containing Secreted 1 (hHSS1) modulates genes and pathways in glioma: implications for the regulation of tumorigenicity and angiogenesis.

Junes-Gill KS, Lawrence CE, Wheeler CJ, Cordner R, Gill TG, Mar V, Shiri L, Basile LA.

BMC Cancer. 2014 Dec 6;14:920. doi: 10.1186/1471-2407-14-920.

4.

T-Lymphocyte Deficiency Exacerbates Behavioral Deficits in the 6-OHDA Unilateral Lesion Rat Model for Parkinson's Disease.

Wheeler CJ, Seksenyan A, Koronyo Y, Rentsendorj A, Sarayba D, Wu H, Gragg A, Siegel E, Thomas D, Espinosa A, Thompson K, Black K, Koronyo-Hamaoui M, Pechnick R, Irvin DK.

J Neurol Neurophysiol. 2014 May;5(3). pii: 209.

5.

Intrinsically de-sialylated CD103(+) CD8 T cells mediate beneficial anti-glioma immune responses.

Jouanneau E, Black KL, Veiga L, Cordner R, Goverdhana S, Zhai Y, Zhang XX, Panwar A, Mardiros A, Wang H, Gragg A, Zandian M, Irvin DK, Wheeler CJ.

Cancer Immunol Immunother. 2014 Sep;63(9):911-24. doi: 10.1007/s00262-014-1559-2. Epub 2014 Jun 4.

PMID:
24893855
6.

Exploitation of adaptive evolution in glioma treatment.

Cordner R, Black KL, Wheeler CJ.

CNS Oncol. 2013 Mar;2(2):171-9. Review.

7.

Transcriptomic profiling of human peritumoral neocortex tissues revealed genes possibly involved in tumor-induced epilepsy.

Niesen CE, Xu J, Fan X, Li X, Wheeler CJ, Mamelak AN, Wang C.

PLoS One. 2013;8(2):e56077. doi: 10.1371/journal.pone.0056077. Epub 2013 Feb 13.

8.

Phase I trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastoma.

Phuphanich S, Wheeler CJ, Rudnick JD, Mazer M, Wang H, Nuño MA, Richardson JE, Fan X, Ji J, Chu RM, Bender JG, Hawkins ES, Patil CG, Black KL, Yu JS.

Cancer Immunol Immunother. 2013 Jan;62(1):125-35. doi: 10.1007/s00262-012-1319-0. Epub 2012 Jul 31.

9.

Vaccines for glioblastoma and high-grade glioma.

Wheeler CJ, Black KL.

Expert Rev Vaccines. 2011 Jun;10(6):875-86. doi: 10.1586/erv.11.71. Review.

PMID:
21692706
10.

hHSS1: a novel secreted factor and suppressor of glioma growth located at chromosome 19q13.33.

Junes-Gill KS, Gallaher TK, Gluzman-Poltorak Z, Miller JD, Wheeler CJ, Fan X, Basile LA.

J Neurooncol. 2011 Apr;102(2):197-211. doi: 10.1007/s11060-010-0314-6. Epub 2010 Jul 31.

11.

T cells enhance stem-like properties and conditional malignancy in gliomas.

Irvin DK, Jouanneau E, Duvall G, Zhang XX, Zhai Y, Sarayba D, Seksenyan A, Panwar A, Black KL, Wheeler CJ.

PLoS One. 2010 Jun 7;5(6):e10974. doi: 10.1371/journal.pone.0010974.

12.

Dendritic cell vaccines to combat glioblastoma.

Wheeler CJ.

Expert Rev Neurother. 2010 Apr;10(4):483-6. doi: 10.1586/ern.10.26. No abstract available.

PMID:
20367199
13.

DCVax-Brain and DC vaccines in the treatment of GBM.

Wheeler CJ, Black KL.

Expert Opin Investig Drugs. 2009 Apr;18(4):509-19. doi: 10.1517/13543780902841951 . Review.

PMID:
19335279
14.

Vaccination elicits correlated immune and clinical responses in glioblastoma multiforme patients.

Wheeler CJ, Black KL, Liu G, Mazer M, Zhang XX, Pepkowitz S, Goldfinger D, Ng H, Irvin D, Yu JS.

Cancer Res. 2008 Jul 15;68(14):5955-64. doi: 10.1158/0008-5472.CAN-07-5973.

15.

Hereditary hemochromatosis: a review of the genetics, mechanism, diagnosis, and treatment of iron overload.

Wheeler CJ, Kowdley KV.

Compr Ther. 2006 Spring;32(1):10-6. Review.

PMID:
16785576
16.

Effect of "helper lipid" on lipoplex electrostatics.

Hirsch-Lerner D, Zhang M, Eliyahu H, Ferrari ME, Wheeler CJ, Barenholz Y.

Biochim Biophys Acta. 2005 Aug 15;1714(2):71-84.

17.

Dendritic cell vaccines and immunity in glioma patients.

Wheeler CJ, Black KL.

Front Biosci. 2005 Sep 1;10:2861-81. Review.

PMID:
15970541
18.

Cytotoxic T cell targeting of TRP-2 sensitizes human malignant glioma to chemotherapy.

Liu G, Akasaki Y, Khong HT, Wheeler CJ, Das A, Black KL, Yu JS.

Oncogene. 2005 Aug 4;24(33):5226-34.

PMID:
15897911
19.

Dendritic cell vaccines and obstacles to beneficial immunity in glioma patients.

Wheeler CJ, Black KL.

Curr Opin Mol Ther. 2005 Feb;7(1):35-47. Review.

PMID:
15732528
20.

Cellular immunity in the treatment of brain tumors.

Wheeler CJ, Yu JS, Black KL.

Clin Neurosurg. 2004;51:132-9. No abstract available.

PMID:
15571138
21.

Clinical responsiveness of glioblastoma multiforme to chemotherapy after vaccination.

Wheeler CJ, Das A, Liu G, Yu JS, Black KL.

Clin Cancer Res. 2004 Aug 15;10(16):5316-26.

22.

HER-2, gp100, and MAGE-1 are expressed in human glioblastoma and recognized by cytotoxic T cells.

Liu G, Ying H, Zeng G, Wheeler CJ, Black KL, Yu JS.

Cancer Res. 2004 Jul 15;64(14):4980-6.

23.

Vaccination with tumor lysate-pulsed dendritic cells elicits antigen-specific, cytotoxic T-cells in patients with malignant glioma.

Yu JS, Liu G, Ying H, Yong WH, Black KL, Wheeler CJ.

Cancer Res. 2004 Jul 15;64(14):4973-9.

24.

Characterization of defective CD4-CD8- T cells in murine tumors generated independent of antigen specificity.

Prins RM, Incardona F, Lau R, Lee P, Claus S, Zhang W, Black KL, Wheeler CJ.

J Immunol. 2004 Feb 1;172(3):1602-11.

25.

Thymic CD8+ T cell production strongly influences tumor antigen recognition and age-dependent glioma mortality.

Wheeler CJ, Black KL, Liu G, Ying H, Yu JS, Zhang W, Lee PK.

J Immunol. 2003 Nov 1;171(9):4927-33.

26.

Intratumoral T cell subset ratios and Fas ligand expression on brain tumor endothelium.

Yu JS, Lee PK, Ehtesham M, Samoto K, Black KL, Wheeler CJ.

J Neurooncol. 2003 Aug-Sep;64(1-2):55-61.

PMID:
12952286
27.

Thymic function and output of recent thymic emigrant T cells during intracranial glioma progression.

Prins RM, Graf MR, Merchant RE, Black KL, Wheeler CJ.

J Neurooncol. 2003 Aug-Sep;64(1-2):45-54.

PMID:
12952285
28.

Molecular and functional analysis of tyrosinase-related protein (TRP)-2 as a cytotoxic T lymphocyte target in patients with malignant glioma.

Liu G, Khong HT, Wheeler CJ, Yu JS, Black KL, Ying H.

J Immunother. 2003 Jul-Aug;26(4):301-12.

PMID:
12843792
29.
30.

Photochemical transfection: a technology for efficient light-directed gene delivery.

Høgset A, Prasmickaite L, Hellum M, Engesaeter BO, Olsen VM, Tjelle TE, Wheeler CJ, Berg K.

Somat Cell Mol Genet. 2002 Nov;27(1-6):97-113. Review.

PMID:
12774944
31.

Salivary gland delivery of pDNA-cationic lipoplexes elicits systemic immune responses.

Sankar V, Baccaglini L, Sawdey M, Wheeler CJ, Pillemer SR, Baum BJ, Atkinson JC.

Oral Dis. 2002 Nov;8(6):275-81.

PMID:
12477057
32.

Synergy between cationic lipid and co-lipid determines the macroscopic structure and transfection activity of lipoplexes.

Ferrari ME, Rusalov D, Enas J, Wheeler CJ.

Nucleic Acids Res. 2002 Apr 15;30(8):1808-16.

33.

In situ adenoviral interleukin 12 gene transfer confers potent and long-lasting cytotoxic immunity in glioma.

Liu Y, Ehtesham M, Samoto K, Wheeler CJ, Thompson RC, Villarreal LP, Black KL, Yu JS.

Cancer Gene Ther. 2002 Jan;9(1):9-15.

34.

Electroporation-facilitated delivery of plasmid DNA in skeletal muscle: plasmid dependence of muscle damage and effect of poloxamer 188.

Hartikka J, Sukhu L, Buchner C, Hazard D, Bozoukova V, Margalith M, Nishioka WK, Wheeler CJ, Manthorp M, Sawdey M.

Mol Ther. 2001 Nov;4(5):407-15.

35.

Phase behavior, DNA ordering, and size instability of cationic lipoplexes. Relevance to optimal transfection activity.

Simberg D, Danino D, Talmon Y, Minsky A, Ferrari ME, Wheeler CJ, Barenholz Y.

J Biol Chem. 2001 Dec 14;276(50):47453-9. Epub 2001 Sep 19.

36.

Vaxfectin enhances antigen specific antibody titers and maintains Th1 type immune responses to plasmid DNA immunization.

Reyes L, Hartikka J, Bozoukova V, Sukhu L, Nishioka W, Singh G, Ferrari M, Enas J, Wheeler CJ, Manthorpe M, Wloch MK.

Vaccine. 2001 Jun 14;19(27):3778-86.

PMID:
11395213
37.

Cationic liposome-mediated gene transfer to rat salivary epithelial cells in vitro and in vivo.

Baccaglini L, Shamsul Hoque AT, Wellner RB, Goldsmith CM, Redman RS, Sankar V, Kingman A, Barnhart KM, Wheeler CJ, Baum BJ.

J Gene Med. 2001 Jan-Feb;3(1):82-90.

PMID:
11269339
38.
39.

Vaxfectin enhances the humoral immune response to plasmid DNA-encoded antigens.

Hartikka J, Bozoukova V, Ferrari M, Sukhu L, Enas J, Sawdey M, Wloch MK, Tonsky K, Norman J, Manthorpe M, Wheeler CJ.

Vaccine. 2001 Feb 28;19(15-16):1911-23.

PMID:
11228361
40.

Vaccination of malignant glioma patients with peptide-pulsed dendritic cells elicits systemic cytotoxicity and intracranial T-cell infiltration.

Yu JS, Wheeler CJ, Zeltzer PM, Ying H, Finger DN, Lee PK, Yong WH, Incardona F, Thompson RC, Riedinger MS, Zhang W, Prins RM, Black KL.

Cancer Res. 2001 Feb 1;61(3):842-7.

41.
42.

Increased levels of surgical adhesions in TGFbeta1 heterozygous mice.

Krause TJ, Katz D, Wheeler CJ, Ebner S, McKinnon RD.

J Invest Surg. 1999 Jan-Feb;12(1):31-8.

PMID:
10084677
43.

Structural requirements for cationic lipid mediated phosphorothioate oligonucleotides delivery to cells in culture.

Bennett CF, Mirejovsky D, Crooke RM, Tsai YJ, Felgner J, Sridhar CN, Wheeler CJ, Felgner PL.

J Drug Target. 1998;5(3):149-62.

PMID:
9606005
44.
45.

Polyreactive antigen-binding B cells are the predominant cell type in the newborn B cell repertoire.

Chen ZJ, Wheeler CJ, Shi W, Wu AJ, Yarboro CH, Gallagher M, Notkins AL.

Eur J Immunol. 1998 Mar;28(3):989-94.

46.
47.

A novel cationic lipid greatly enhances plasmid DNA delivery and expression in mouse lung.

Wheeler CJ, Felgner PL, Tsai YJ, Marshall J, Sukhu L, Doh SG, Hartikka J, Nietupski J, Manthorpe M, Nichols M, Plewe M, Liang X, Norman J, Smith A, Cheng SH.

Proc Natl Acad Sci U S A. 1996 Oct 15;93(21):11454-9.

48.

A new cationic liposome DNA complex enhances the efficiency of arterial gene transfer in vivo.

Stephan DJ, Yang ZY, San H, Simari RD, Wheeler CJ, Felgner PL, Gordon D, Nabel GJ, Nabel EG.

Hum Gene Ther. 1996 Oct 1;7(15):1803-12.

49.

Lipid prodrugs of phosphonoacids: greatly enhanced antiviral activity of 1-O-octadecyl-sn-glycero-3-phosphonoformate in HIV-1, HSV-1 and HCMV-infected cells, in vitro.

Hostetler KY, Kini GD, Beadle JR, Aldern KA, Gardner MF, Border R, Kumar R, Barshak L, Sridhar CN, Wheeler CJ, Richman DD.

Antiviral Res. 1996 Jun;31(1-2):59-67.

PMID:
8793009
50.

Converting an alcohol to an amine in a cationic lipid dramatically alters the co-lipid requirement, cellular transfection activity and the ultrastructure of DNA-cytofectin complexes.

Wheeler CJ, Sukhu L, Yang G, Tsai Y, Bustamente C, Felgner P, Norman J, Manthorpe M.

Biochim Biophys Acta. 1996 Apr 3;1280(1):1-11.

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