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Plasmodium Condensin Core Subunits SMC2/SMC4 Mediate Atypical Mitosis and Are Essential for Parasite Proliferation and Transmission.

Pandey R, Abel S, Boucher M, Wall RJ, Zeeshan M, Rea E, Freville A, Lu XM, Brady D, Daniel E, Stanway RR, Wheatley S, Batugedara G, Hollin T, Bottrill AR, Gupta D, Holder AA, Le Roch KG, Tewari R.

Cell Rep. 2020 Feb 11;30(6):1883-1897.e6. doi: 10.1016/j.celrep.2020.01.033.


A recombinant platform for flavivirus vaccines and diagnostics using chimeras of a new insect-specific virus.

Hobson-Peters J, Harrison JJ, Watterson D, Hazlewood JE, Vet LJ, Newton ND, Warrilow D, Colmant AMG, Taylor C, Huang B, Piyasena TBH, Chow WK, Setoh YX, Tang B, Nakayama E, Yan K, Amarilla AA, Wheatley S, Moore PR, Finger M, Kurucz N, Modhiran N, Young PR, Khromykh AA, Bielefeldt-Ohmann H, Suhrbier A, Hall RA.

Sci Transl Med. 2019 Dec 11;11(522). pii: eaax7888. doi: 10.1126/scitranslmed.aax7888.


The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis.

Capalbo L, Bassi ZI, Geymonat M, Todesca S, Copoiu L, Enright AJ, Callaini G, Riparbelli MG, Yu L, Choudhary JS, Ferrero E, Wheatley S, Douglas ME, Mishima M, D'Avino PP.

Nat Commun. 2019 Oct 4;10(1):4513. doi: 10.1038/s41467-019-12507-9.


Transporting cells over several days without dry-ice.

Wheatley SP, Wheatley DN.

J Cell Sci. 2019 Nov 1;132(21). pii: jcs238139. doi: 10.1242/jcs.238139.


Are Bitcoin bubbles predictable? Combining a generalized Metcalfe's Law and the Log-Periodic Power Law Singularity model.

Wheatley S, Sornette D, Huber T, Reppen M, Gantner RN.

R Soc Open Sci. 2019 Jun 5;6(6):180538. doi: 10.1098/rsos.180538. eCollection 2019 Jun.


Survivin at a glance.

Wheatley SP, Altieri DC.

J Cell Sci. 2019 Apr 4;132(7). pii: jcs223826. doi: 10.1242/jcs.223826. Review.


Engulfment, persistence and fate of Bdellovibrio bacteriovorus predators inside human phagocytic cells informs their future therapeutic potential.

Raghunathan D, Radford PM, Gell C, Negus D, Moore C, Till R, Tighe PJ, Wheatley SP, Martinez-Pomares L, Sockett RE, Tyson J.

Sci Rep. 2019 Mar 12;9(1):4293. doi: 10.1038/s41598-019-40223-3.


Classification of cryptocurrency coins and tokens by the dynamics of their market capitalizations.

Wu K, Wheatley S, Sornette D.

R Soc Open Sci. 2018 Sep 5;5(9):180381. doi: 10.1098/rsos.180381. eCollection 2018 Sep.


The use of decellularised animal tissue to study disseminating cancer cells.

Grey JFE, Campbell-Ritchie A, Everitt NM, Fezovich AJ, Wheatley SP.

J Cell Sci. 2018 Dec 10;132(4). pii: jcs219907. doi: 10.1242/jcs.219907.


Survivin inhibits excessive autophagy in cancer cells but does so independently of its interaction with LC3.

Humphry NJ, Wheatley SP.

Biol Open. 2018 Oct 22;7(10). pii: bio037374. doi: 10.1242/bio.037374.


Author Correction: Plasmodium APC3 mediates chromosome condensation and cytokinesis during atypical mitosis in male gametogenesis.

Wall RJ, Ferguson DJP, Freville A, Franke-Fayard B, Brady D, Zeeshan M, Bottrill AR, Wheatley S, Fry AM, Janse CJ, Yamano H, Holder AA, Guttery DS, Tewari R.

Sci Rep. 2018 Aug 21;8(1):12814. doi: 10.1038/s41598-018-30924-6.


Responding to the marauding terror attack: the police perspective.

Wheatley S, Hollingsworth AC, Greaves I.

J R Army Med Corps. 2018 Jul 16. pii: jramc-2018-000960. doi: 10.1136/jramc-2018-000960. [Epub ahead of print]


Detection of Specific ZIKV IgM in Travelers Using a Multiplexed Flavivirus Microsphere Immunoassay.

Taylor CT, Mackay IM, McMahon JL, Wheatley SL, Moore PR, Finger MJ, Hewitson GR, Moore FA.

Viruses. 2018 May 12;10(5). pii: E253. doi: 10.3390/v10050253.


Efficacy of anthropometric measures for identifying cardiovascular disease risk in adolescents: review and meta-analysis.

Lichtenauer M, Wheatley SD, Martyn-St James M, Duncan MJ, Cobayashi F, Berg G, Musso C, Graffigna M, Soutelo J, Bovet P, Kollias A, Stergiou GS, Grammatikos E, Griffiths C, Ingle L, Jung C.

Minerva Pediatr. 2018 Aug;70(4):371-382. doi: 10.23736/S0026-4946.18.05175-7. Epub 2018 Apr 12. Review.


Plasmodium APC3 mediates chromosome condensation and cytokinesis during atypical mitosis in male gametogenesis.

Wall RJ, Ferguson DJP, Freville A, Franke-Fayard B, Brady D, Zeeshan M, Bottrill AR, Wheatley S, Fry AM, Janse CJ, Yamano H, Holder AA, Guttery DS, Tewari R.

Sci Rep. 2018 Apr 4;8(1):5610. doi: 10.1038/s41598-018-23871-9. Erratum in: Sci Rep. 2018 Aug 21;8(1):12814.


Clinical audit of estradiol implant therapy: Long duration of action and implications in non-hysterectomised women.

Wheatley S, Bell RJ, Stuckey BG, Robinson PJ, Davis SR.

Maturitas. 2016 Dec;94:84-86. doi: 10.1016/j.maturitas.2016.09.008. Epub 2016 Sep 15.


Clonidine Overdose in a Toddler Due to Accidental Ingestion of a Compounding Cream.

Cates AL, Wheatley SM, Katz KD.

Pediatr Emerg Care. 2018 Apr;34(4):e79-e81. doi: 10.1097/PEC.0000000000000790.


Case Series of Synthetic Cannabinoid Intoxication from One Toxicology Center.

Katz KD, Leonetti AL, Bailey BC, Surmaitis RM, Eustice ER, Kacinko S, Wheatley SM.

West J Emerg Med. 2016 May;17(3):290-4. doi: 10.5811/westjem.2016.2.29519. Epub 2016 Apr 26.


The N-terminus of survivin is a mitochondrial-targeting sequence and Src regulator.

Dunajová L, Cash E, Markus R, Rochette S, Townley AR, Wheatley SP.

J Cell Sci. 2016 Jul 15;129(14):2707-12. doi: 10.1242/jcs.183277. Epub 2016 May 31.


Of Disasters and Dragon Kings: A Statistical Analysis of Nuclear Power Incidents and Accidents.

Wheatley S, Sovacool B, Sornette D.

Risk Anal. 2017 Jan;37(1):99-115. doi: 10.1111/risa.12587. Epub 2016 Mar 22.


Plasmodium P-Type Cyclin CYC3 Modulates Endomitotic Growth during Oocyst Development in Mosquitoes.

Roques M, Wall RJ, Douglass AP, Ramaprasad A, Ferguson DJ, Kaindama ML, Brusini L, Joshi N, Rchiad Z, Brady D, Guttery DS, Wheatley SP, Yamano H, Holder AA, Pain A, Wickstead B, Tewari R.

PLoS Pathog. 2015 Nov 13;11(11):e1005273. doi: 10.1371/journal.ppat.1005273. eCollection 2015 Nov.


Mitotic activity of survivin is regulated by acetylation at K129.

Aljaberi AM, Webster JR, Wheatley SP.

Cell Cycle. 2015;14(11):1738-47. doi: 10.1080/15384101.2015.1033597.


The functional repertoire of survivin's tails.

Wheatley SP.

Cell Cycle. 2015;14(2):261-8. doi: 10.4161/15384101.2014.979680.


Sox2 acts as a transcriptional repressor in neural stem cells.

Liu YR, Laghari ZA, Novoa CA, Hughes J, Webster JR, Goodwin PE, Wheatley SP, Scotting PJ.

BMC Neurosci. 2014 Aug 8;15:95. doi: 10.1186/1471-2202-15-95.


Analysis of the functional repertoire of a mutant form of survivin, K129E, which has been linked to lung cancer.

Aljaberi AM, Webster JR, Wheatley SP.

Cancer Cell Int. 2014 Aug 19;14:78. doi: 10.1186/s12935-014-0078-8. eCollection 2014.


Protein synthesis in skeletal muscle of neonatal pigs is enhanced by administration of β-hydroxy-β-methylbutyrate.

Wheatley SM, El-Kadi SW, Suryawan A, Boutry C, Orellana RA, Nguyen HV, Davis SR, Davis TA.

Am J Physiol Endocrinol Metab. 2014 Jan 1;306(1):E91-9. doi: 10.1152/ajpendo.00500.2013. Epub 2013 Nov 5.


Leucine pulses enhance skeletal muscle protein synthesis during continuous feeding in neonatal pigs.

Boutry C, El-Kadi SW, Suryawan A, Wheatley SM, Orellana RA, Kimball SR, Nguyen HV, Davis TA.

Am J Physiol Endocrinol Metab. 2013 Sep 1;305(5):E620-31. doi: 10.1152/ajpendo.00135.2013. Epub 2013 Jul 9.


The Plasmodium berghei Ca(2+)/H(+) exchanger, PbCAX, is essential for tolerance to environmental Ca(2+) during sexual development.

Guttery DS, Pittman JK, Frénal K, Poulin B, McFarlane LR, Slavic K, Wheatley SP, Soldati-Favre D, Krishna S, Tewari R, Staines HM.

PLoS Pathog. 2013 Feb;9(2):e1003191. doi: 10.1371/journal.ppat.1003191. Epub 2013 Feb 28.


Chromosome 'by-Aurora-ientation' during mitosis.

Wheatley SP.

Cell Biol Int. 2011 Jun;35(6):575-8. doi: 10.1042/CBI20100911.


Genomic DNA damage and ATR-Chk1 signaling determine oncolytic adenoviral efficacy in human ovarian cancer cells.

Connell CM, Shibata A, Tookman LA, Archibald KM, Flak MB, Pirlo KJ, Lockley M, Wheatley SP, McNeish IA.

J Clin Invest. 2011 Apr;121(4):1283-97. doi: 10.1172/JCI43976. Epub 2011 Mar 7.


The polo-like kinase inhibitor BI 2536 exhibits potent activity against malignant plasma cells and represents a novel therapy in multiple myeloma.

Stewart HJ, Kishikova L, Powell FL, Wheatley SP, Chevassut TJ.

Exp Hematol. 2011 Mar;39(3):330-8. doi: 10.1016/j.exphem.2010.12.006. Epub 2010 Dec 22.


Raman spectroscopy in head and neck cancer.

Harris AT, Rennie A, Waqar-Uddin H, Wheatley SR, Ghosh SK, Martin-Hirsch DP, Fisher SE, High AS, Kirkham J, Upile T.

Head Neck Oncol. 2010 Oct 5;2:26. doi: 10.1186/1758-3284-2-26. Review.


p21 Promotes oncolytic adenoviral activity in ovarian cancer and is a potential biomarker.

Flak MB, Connell CM, Chelala C, Archibald K, Salako MA, Pirlo KJ, Lockley M, Wheatley SP, Balkwill FR, McNeish IA.

Mol Cancer. 2010 Jul 3;9:175. doi: 10.1186/1476-4598-9-175.


Liaisons between survivin and Plk1 during cell division and cell death.

Colnaghi R, Wheatley SP.

J Biol Chem. 2010 Jul 16;285(29):22592-604. doi: 10.1074/jbc.M109.065003. Epub 2010 Apr 28.


Phosphorylation of survivin at threonine 34 inhibits its mitotic function and enhances its cytoprotective activity.

Barrett RM, Osborne TP, Wheatley SP.

Cell Cycle. 2009 Jan 15;8(2):278-83. Epub 2009 Jan 10.


Nuclear survivin abrogates multiple cell cycle checkpoints and enhances viral oncolysis.

Connell CM, Wheatley SP, McNeish IA.

Cancer Res. 2008 Oct 1;68(19):7923-31. doi: 10.1158/0008-5472.CAN-08-0817.


Endopolyploidy in irradiated p53-deficient tumour cell lines: persistence of cell division activity in giant cells expressing Aurora-B kinase.

Erenpreisa J, Ivanov A, Wheatley SP, Kosmacek EA, Ianzini F, Anisimov AP, Mackey M, Davis PJ, Plakhins G, Illidge TM.

Cell Biol Int. 2008 Sep;32(9):1044-56. doi: 10.1016/j.cellbi.2008.06.003. Epub 2008 Jun 17.


Emotional intelligence of veterinary students.

Wheatley S.

Vet Rec. 2008 Apr 12;162(15):492. No abstract available.


Nuclear survivin has reduced stability and is not cytoprotective.

Connell CM, Colnaghi R, Wheatley SP.

J Biol Chem. 2008 Feb 8;283(6):3289-96. Epub 2007 Dec 5.


Phosphorylation by aurora-B negatively regulates survivin function during mitosis.

Wheatley SP, Barrett RM, Andrews PD, Medema RH, Morley SJ, Swedlow JR, Lens SM.

Cell Cycle. 2007 May 15;6(10):1220-30. Epub 2007 May 21.


Involvement of centrosome amplification in radiation-induced mitotic catastrophe.

Dodson H, Wheatley SP, Morrison CG.

Cell Cycle. 2007 Feb 1;6(3):364-70. Epub 2007 Feb 11.


Separating the anti-apoptotic and mitotic roles of survivin.

Colnaghi R, Connell CM, Barrett RM, Wheatley SP.

J Biol Chem. 2006 Nov 3;281(44):33450-6. Epub 2006 Sep 1.


Survivin: a protein with dual roles in mitosis and apoptosis.

Wheatley SP, McNeish IA.

Int Rev Cytol. 2005;247:35-88. Review.


Molecular analysis of survivin isoforms: evidence that alternatively spliced variants do not play a role in mitosis.

Noton EA, Colnaghi R, Tate S, Starck C, Carvalho A, Ko Ferrigno P, Wheatley SP.

J Biol Chem. 2006 Jan 13;281(2):1286-95. Epub 2005 Nov 16.


Survivin interacts with Smac/DIABLO in ovarian carcinoma cells but is redundant in Smac-mediated apoptosis.

McNeish IA, Lopes R, Bell SJ, McKay TR, Fernandez M, Lockley M, Wheatley SP, Lemoine NR.

Exp Cell Res. 2005 Jan 1;302(1):69-82.


Exploring and enhancing engagement to the psychosocial intervention 'Preparing for Parenthood'.

Wheatley SL, Brugha TS, Shapiro DA.

Arch Womens Ment Health. 2003 Nov;6(4):275-85.


Aurora-B phosphorylation in vitro identifies a residue of survivin that is essential for its localization and binding to inner centromere protein (INCENP) in vivo.

Wheatley SP, Henzing AJ, Dodson H, Khaled W, Earnshaw WC.

J Biol Chem. 2004 Feb 13;279(7):5655-60. Epub 2003 Nov 10.


Survivin is required for stable checkpoint activation in taxol-treated HeLa cells.

Carvalho A, Carmena M, Sambade C, Earnshaw WC, Wheatley SP.

J Cell Sci. 2003 Jul 15;116(Pt 14):2987-98. Epub 2003 Jun 3.


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