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The utility of routine surveillance screening with magnetic resonance imaging to detect tumor recurrence/progression in children with high-grade central nervous system tumors: a systematic review.

Stevens SP, Main C, Bailey S, Pizer B, English M, Phillips B, Peet A, Avula S, Wilne S, Wheatley K, Kearns PR, Wilson JS.

Pediatr Blood Cancer. 2018 Nov 8:e27509. doi: 10.1002/pbc.27509. [Epub ahead of print] Review.


High-Dose Chemotherapy and Blood Autologous Stem-Cell Rescue Compared With Standard Chemotherapy in Localized High-Risk Ewing Sarcoma: Results of Euro-E.W.I.N.G.99 and Ewing-2008.

Whelan J, Le Deley MC, Dirksen U, Le Teuff G, Brennan B, Gaspar N, Hawkins DS, Amler S, Bauer S, Bielack S, Blay JY, Burdach S, Castex MP, Dilloo D, Eggert A, Gelderblom H, Gentet JC, Hartmann W, Hassenpflug WA, Hjorth L, Jimenez M, Klingebiel T, Kontny U, Kruseova J, Ladenstein R, Laurence V, Lervat C, Marec-Berard P, Marreaud S, Michon J, Morland B, Paulussen M, Ranft A, Reichardt P, van den Berg H, Wheatley K, Judson I, Lewis I, Craft A, Juergens H, Oberlin O; Euro-E.W.I.N.G.99 and EWING-2008 Investigators.

J Clin Oncol. 2018 Sep 6:JCO2018782516. doi: 10.1200/JCO.2018.78.2516. [Epub ahead of print]


Hydroxycarbamide Plus Aspirin Versus Aspirin Alone in Patients With Essential Thrombocythemia Age 40 to 59 Years Without High-Risk Features.

Godfrey AL, Campbell PJ, MacLean C, Buck G, Cook J, Temple J, Wilkins BS, Wheatley K, Nangalia J, Grinfeld J, McMullin MF, Forsyth C, Kiladjian JJ, Green AR, Harrison CN; United Kingdom Medical Research Council Primary Thrombocythemia-1 Study; United Kingdom National Cancer Research Institute Myeloproliferative Neoplasms Subgroup; French Intergroup of Myeloproliferative Neoplasms; and the Australasian Leukaemia and Lymphoma Group.

J Clin Oncol. 2018 Aug 28:JCO2018788414. doi: 10.1200/JCO.2018.78.8414. [Epub ahead of print]


The utility of routine surveillance screening with magnetic resonance imaging (MRI) to detect tumour recurrence in children with low-grade central nervous system (CNS) tumours: a systematic review.

Stevens SP, Main C, Bailey S, Pizer B, English M, Phillips R, Peet A, Avula S, Wilne S, Wheatley K, Kearns PR, Wilson JS.

J Neurooncol. 2018 Sep;139(3):507-522. doi: 10.1007/s11060-018-2901-x. Epub 2018 Jun 9. Review.


PEPtalk2: results of a pilot randomised controlled trial to compare VZIG and aciclovir as postexposure prophylaxis (PEP) against chickenpox in children with cancer.

Bate J, Baker S, Breuer J, Chisholm JC, Gray J, Hambleton S, Houlton A, Jit M, Lowis S, Makin G, O'Sullivan C, Patel SR, Phillips R, Ransinghe N, Ramsay ME, Skinner R, Wheatley K, Heath PT.

Arch Dis Child. 2018 May 5. pii: archdischild-2017-314212. doi: 10.1136/archdischild-2017-314212. [Epub ahead of print]


Lee Silverman Voice Treatment versus standard speech and language therapy versus control in Parkinson's disease: a pilot randomised controlled trial (PD COMM pilot).

Sackley CM, Smith CH, Rick CE, Brady MC, Ives N, Patel S, Woolley R, Dowling F, Patel R, Roberts H, Jowett S, Wheatley K, Kelly D, Sands G, Clarke CE; PD COMM Pilot Collaborative Group.

Pilot Feasibility Stud. 2018 Jan 10;4:30. doi: 10.1186/s40814-017-0222-z. eCollection 2018.


Mutational analysis of disease relapse in patients allografted for acute myeloid leukemia.

Quek L, Ferguson P, Metzner M, Ahmed I, Kennedy A, Garnett C, Jeffries S, Walter C, Piechocki K, Timbs A, Danby R, Raghavan M, Peniket A, Griffiths M, Bacon A, Ward J, Wheatley K, Vyas P, Craddock C.

Blood Adv. 2016 Dec 14;1(3):193-204. doi: 10.1182/bloodadvances.2016000760. eCollection 2016 Dec 27.


Immunohistochemical evaluation of molecular radiotherapy target expression in neuroblastoma tissue.

Gains JE, Sebire NJ, Moroz V, Wheatley K, Gaze MN.

Eur J Nucl Med Mol Imaging. 2018 Mar;45(3):402-411. doi: 10.1007/s00259-017-3856-4. Epub 2017 Oct 17.


Relapse-Free Survival as a Surrogate for Overall Survival in the Evaluation of Stage II-III Melanoma Adjuvant Therapy.

Suciu S, Eggermont AMM, Lorigan P, Kirkwood JM, Markovic SN, Garbe C, Cameron D, Kotapati S, Chen TT, Wheatley K, Ives N, de Schaetzen G, Efendi A, Buyse M.

J Natl Cancer Inst. 2018 Jan 1;110(1). doi: 10.1093/jnci/djx133. Review.


Outcome of Azacitidine Therapy in Acute Myeloid Leukemia Is not Improved by Concurrent Vorinostat Therapy but Is Predicted by a Diagnostic Molecular Signature.

Craddock CF, Houlton AE, Quek LS, Ferguson P, Gbandi E, Roberts C, Metzner M, Garcia-Martin N, Kennedy A, Hamblin A, Raghavan M, Nagra S, Dudley L, Wheatley K, McMullin MF, Pillai SP, Kelly RJ, Siddique S, Dennis M, Cavenagh JD, Vyas P.

Clin Cancer Res. 2017 Nov 1;23(21):6430-6440. doi: 10.1158/1078-0432.CCR-17-1423. Epub 2017 Aug 1.


Adjuvant interferon-α for the treatment of high-risk melanoma: An individual patient data meta-analysis.

Ives NJ, Suciu S, Eggermont AMM, Kirkwood J, Lorigan P, Markovic SN, Garbe C, Wheatley K; International Melanoma Meta-Analysis Collaborative Group (IMMCG).

Eur J Cancer. 2017 Sep;82:171-183. doi: 10.1016/j.ejca.2017.06.006. Epub 2017 Jul 7. Review.


Investigating the heterogeneity of alkylating agents' efficacy and toxicity between sexes: A systematic review and meta-analysis of randomized trials comparing cyclophosphamide and ifosfamide (MAIAGE study).

Fresneau B, Hackshaw A, Hawkins DS, Paulussen M, Anderson JR, Judson I, Litière S, Dirksen U, Lewis I, van den Berg H, Gaspar N, Gelderblom H, Whelan J, Boddy AV, Wheatley K, Pignon JP, De Vathaire F, Le Deley MC, Le Teuff G.

Pediatr Blood Cancer. 2017 Aug;64(8). doi: 10.1002/pbc.26457. Epub 2017 Jan 23. Review.


Effect of topical imiquimod as primary treatment for lentigo maligna: the LIMIT-1 study.

Marsden JR, Fox R, Boota NM, Cook M, Wheatley K, Billingham LJ, Steven NM; NCRI Skin Cancer Clinical Studies Group, the U.K. Dermatology Clinical Trials Network and the LIMIT-1 Collaborative Group.

Br J Dermatol. 2017 May;176(5):1148-1154. doi: 10.1111/bjd.15112. Epub 2017 Apr 10.


Clinical effectiveness and cost-effectiveness of physiotherapy and occupational therapy versus no therapy in mild to moderate Parkinson's disease: a large pragmatic randomised controlled trial (PD REHAB).

Clarke CE, Patel S, Ives N, Rick CE, Woolley R, Wheatley K, Walker MF, Zhu S, Kandiyali R, Yao G, Sackley CM.

Health Technol Assess. 2016 Aug;20(63):1-96. doi: 10.3310/hta20630.


The impact of routine surveillance screening with magnetic resonance imaging (MRI) to detect tumour recurrence in children with central nervous system (CNS) tumours: protocol for a systematic review and meta-analysis.

Main C, Stevens SP, Bailey S, Phillips R, Pizer B, Wheatley K, Kearns PR, English M, Wilne S, Wilson JS.

Syst Rev. 2016 Aug 31;5(1):143. doi: 10.1186/s13643-016-0318-1. Review.


Home-based Reach-to-Grasp training for people after stroke is feasible: a pilot randomised controlled trial.

Turton AJ, Cunningham P, van Wijck F, Smartt H, Rogers CA, Sackley CM, Jowett S, Wolf SL, Wheatley K, van Vliet P.

Clin Rehabil. 2017 Jul;31(7):891-903. doi: 10.1177/0269215516661751. Epub 2016 Jul 28.


Reply to response to Wheatley et al., "Surgical excision margins in primary cutaneous melanoma: A meta-analysis and Bayesian probability evaluation" Cancer Treatment Reviews April 2016;45:76.

Wheatley K, Wilson JS, Gaunt P, Marsden JR.

Cancer Treat Rev. 2017 Apr;55:225-229. doi: 10.1016/j.ctrv.2016.07.002. Epub 2016 Jul 15. No abstract available.


The effectiveness and safety of proton beam radiation therapy in children with malignant central nervous system (CNS) tumours: protocol for a systematic review.

Main C, Dandapani M, Pritchard M, Dodds R, Stevens SP, Thorp N, Taylor RE, Wheatley K, Pizer B, Morrall M, Phillips R, English M, Kearns PR, Wilne S, Wilson JS.

Syst Rev. 2016 Jul 27;5(1):124. doi: 10.1186/s13643-016-0285-6. Review.


Effect of renal artery revascularization upon cardiac structure and function in atherosclerotic renal artery stenosis: cardiac magnetic resonance sub-study of the ASTRAL trial.

Ritchie J, Green D, Chrysochou T, Hegarty J, Handley K, Ives N, Wheatley K, Houston G, Wright J, Neyses L, Chalmers N, Mark P, Patel R, Moss J, Roditi G, Eadington D, Lukaschuk E, Cleland J, Kalra PA.

Nephrol Dial Transplant. 2017 Jun 1;32(6):1006-1013. doi: 10.1093/ndt/gfw107.


Bortezomib for the treatment of multiple myeloma.

Scott K, Hayden PJ, Will A, Wheatley K, Coyne I.

Cochrane Database Syst Rev. 2016 Apr 20;4:CD010816. doi: 10.1002/14651858.CD010816.pub2. Review.


An Occupational Therapy intervention for residents with stroke-related disabilities in UK Care Homes (OTCH): cluster randomised controlled trial with economic evaluation.

Sackley CM, Walker MF, Burton CR, Watkins CL, Mant J, Roalfe AK, Wheatley K, Sheehan B, Sharp L, Stant KE, Fletcher-Smith J, Steel K, Barton GR, Irvine L, Peryer G; OTCH investigators.

Health Technol Assess. 2016 Feb;20(15):1-138. doi: 10.3310/hta20150.


Dive characteristics can predict foraging success in Australian fur seals (Arctocephalus pusillus doriferus) as validated by animal-borne video.

Volpov BL, Rosen DA, Hoskins AJ, Lourie HJ, Dorville N, Baylis AM, Wheatley KE, Marshall G, Abernathy K, Semmens J, Hindell MA, Arnould JP.

Biol Open. 2016 Feb 12;5(3):262-71. doi: 10.1242/bio.016659.


Cost-utility analysis of deep brain stimulation surgery plus best medical therapy versus best medical therapy in patients with Parkinson's: Economic evaluation alongside the PD SURG trial.

McIntosh E, Gray A, Daniels J, Gill S, Ives N, Jenkinson C, Mitchell R, Pall H, Patel S, Quinn N, Rick C, Wheatley K, Williams A; PD SURG Collaborators Group.

Mov Disord. 2016 Aug;31(8):1173-82. doi: 10.1002/mds.26423. Epub 2016 Feb 5.


Physiotherapy and Occupational Therapy vs No Therapy in Mild to Moderate Parkinson Disease: A Randomized Clinical Trial.

Clarke CE, Patel S, Ives N, Rick CE, Dowling F, Woolley R, Wheatley K, Walker MF, Sackley CM; PD REHAB Collaborative Group.

JAMA Neurol. 2016 Mar;73(3):291-9. doi: 10.1001/jamaneurol.2015.4452.


The role of high-dose myeloablative chemotherapy with haematopoietic stem cell transplantation (HSCT) in children with central nervous system (CNS) tumours: protocol for a systematic review and meta-analysis.

Main C, Wilson JS, Stevens SP, Houlton AE, English M, Kearns PR, Phillips B, Pizer B, Wilne S, Wheatley K.

Syst Rev. 2015 Nov 20;4:168. doi: 10.1186/s13643-015-0155-7. Review.


Surgical excision margins in primary cutaneous melanoma: A meta-analysis and Bayesian probability evaluation.

Wheatley K, Wilson JS, Gaunt P, Marsden JR.

Cancer Treat Rev. 2016 Jan;42:73-81. doi: 10.1016/j.ctrv.2015.10.013. Epub 2015 Nov 10. Review.


Comparing results from long and short form versions of the Parkinson's disease questionnaire in a longitudinal study.

Jenkinson C, Clarke C, Gray R, Hewitson P, Ives N, Morley D, Rick C, Wheatley K, Williams A.

Parkinsonism Relat Disord. 2015 Nov;21(11):1312-6. doi: 10.1016/j.parkreldis.2015.09.008. Epub 2015 Sep 3.


Impact of gender on efficacy and acute toxicity of alkylating agent -based chemotherapy in Ewing sarcoma: secondary analysis of the Euro-Ewing99-R1 trial.

van den Berg H, Paulussen M, Le Teuff G, Judson I, Gelderblom H, Dirksen U, Brennan B, Whelan J, Ladenstein RL, Marec-Berard P, Kruseova J, Hjorth L, Kühne T, Brichard B, Wheatley K, Craft A, Juergens H, Gaspar N, Le Deley MC; Euro-EWING99 Group.

Eur J Cancer. 2015 Nov;51(16):2453-64. doi: 10.1016/j.ejca.2015.06.123. Epub 2015 Aug 10.


Identification of Prey Captures in Australian Fur Seals (Arctocephalus pusillus doriferus) Using Head-Mounted Accelerometers: Field Validation with Animal-Borne Video Cameras.

Volpov BL, Hoskins AJ, Battaile BC, Viviant M, Wheatley KE, Marshall G, Abernathy K, Arnould JP.

PLoS One. 2015 Jun 24;10(6):e0128789. doi: 10.1371/journal.pone.0128789. eCollection 2015.


An occupational therapy intervention for residents with stroke related disabilities in UK care homes (OTCH): cluster randomised controlled trial.

Sackley CM, Walker MF, Burton CR, Watkins CL, Mant J, Roalfe AK, Wheatley K, Sheehan B, Sharp L, Stant KE, Fletcher-Smith J, Steel K, Wilde K, Irvine L, Peryer G; OTCH trial investigators.

BMJ. 2015 Feb 5;350:h468. doi: 10.1136/bmj.h468.


Systematic review and meta-analysis of hydrocarbon exposure and the risk of Parkinson's disease.

Palin O, Herd C, Morrison KE, Jagielski AC, Wheatley K, Thomas GN, Clarke CE.

Parkinsonism Relat Disord. 2015 Mar;21(3):243-8. doi: 10.1016/j.parkreldis.2014.12.017. Epub 2014 Dec 26. Review.


Clinical trial designs for rare diseases: studies developed and discussed by the International Rare Cancers Initiative.

Bogaerts J, Sydes MR, Keat N, McConnell A, Benson A, Ho A, Roth A, Fortpied C, Eng C, Peckitt C, Coens C, Pettaway C, Arnold D, Hall E, Marshall E, Sclafani F, Hatcher H, Earl H, Ray-Coquard I, Paul J, Blay JY, Whelan J, Panageas K, Wheatley K, Harrington K, Licitra L, Billingham L, Hensley M, McCabe M, Patel PM, Carvajal R, Wilson R, Glynne-Jones R, McWilliams R, Leyvraz S, Rao S, Nicholson S, Filiaci V, Negrouk A, Lacombe D, Dupont E, Pauporté I, Welch JJ, Law K, Trimble T, Seymour M.

Eur J Cancer. 2015 Feb;51(3):271-81. doi: 10.1016/j.ejca.2014.10.027. Epub 2014 Dec 24. Review.


Treatment Reasons, Resource use and Costs of Hospitalisations in People with Parkinson's: Results from a Large Rct.

Xin Y, Clarke CE, Muzerengi S, Rick CE, Gray A, Gray R, Wheatley K, Ives N, McIntosh E.

Value Health. 2014 Nov;17(7):A809. doi: 10.1016/j.jval.2014.08.541. Epub 2014 Oct 26. No abstract available.


Mylotarg has potent anti-leukaemic effect: a systematic review and meta-analysis of anti-CD33 antibody treatment in acute myeloid leukaemia.

Loke J, Khan JN, Wilson JS, Craddock C, Wheatley K.

Ann Hematol. 2015 Mar;94(3):361-73. doi: 10.1007/s00277-014-2218-6. Epub 2014 Oct 5. Review.


Cyclophosphamide compared with ifosfamide in consolidation treatment of standard-risk Ewing sarcoma: results of the randomized noninferiority Euro-EWING99-R1 trial.

Le Deley MC, Paulussen M, Lewis I, Brennan B, Ranft A, Whelan J, Le Teuff G, Michon J, Ladenstein R, Marec-Bérard P, van den Berg H, Hjorth L, Wheatley K, Judson I, Juergens H, Craft A, Oberlin O, Dirksen U.

J Clin Oncol. 2014 Aug 10;32(23):2440-8. doi: 10.1200/JCO.2013.54.4833. Epub 2014 Jun 30.


Physiotherapy for Parkinson's disease: a comparison of techniques.

Tomlinson CL, Herd CP, Clarke CE, Meek C, Patel S, Stowe R, Deane KH, Shah L, Sackley CM, Wheatley K, Ives N.

Cochrane Database Syst Rev. 2014 Jun 17;(6):CD002815. doi: 10.1002/14651858.CD002815.pub2. Review.


Long-term effectiveness of dopamine agonists and monoamine oxidase B inhibitors compared with levodopa as initial treatment for Parkinson's disease (PD MED): a large, open-label, pragmatic randomised trial.

PD Med Collaborative Group, Gray R, Ives N, Rick C, Patel S, Gray A, Jenkinson C, McIntosh E, Wheatley K, Williams A, Clarke CE.

Lancet. 2014 Sep 27;384(9949):1196-205. doi: 10.1016/S0140-6736(14)60683-8. Epub 2014 Jun 11. Erratum in: Lancet. 2014 Sep 27;384(9949):1186.


Lee Silverman voice treatment versus standard NHS speech and language therapy versus control in Parkinson's disease (PD COMM pilot): study protocol for a randomized controlled trial.

Sackley CM, Smith CH, Rick C, Brady MC, Ives N, Patel R, Roberts H, Dowling F, Jowett S, Wheatley K, Patel S, Kelly D, Sands G, Clarke C.

Trials. 2014 Jun 7;15:213. doi: 10.1186/1745-6215-15-213.


Hyperfractionated Accelerated Radiotherapy (HART) with maintenance chemotherapy for metastatic (M1-3) Medulloblastoma--a safety/feasibility study.

Taylor RE, Howman AJ, Wheatley K, Brogden EE, Large B, Gibson MJ, Robson K, Mitra D, Saran F, Michalski A, Pizer BL.

Radiother Oncol. 2014 Apr;111(1):41-6. doi: 10.1016/j.radonc.2014.01.022. Epub 2014 Mar 11.


A systematic review of 131I-meta iodobenzylguanidine molecular radiotherapy for neuroblastoma.

Wilson JS, Gains JE, Moroz V, Wheatley K, Gaze MN.

Eur J Cancer. 2014 Mar;50(4):801-15. doi: 10.1016/j.ejca.2013.11.016. Epub 2013 Dec 12. Review.


Physiotherapy versus placebo or no intervention in Parkinson's disease.

Tomlinson CL, Patel S, Meek C, Herd CP, Clarke CE, Stowe R, Shah L, Sackley CM, Deane KH, Wheatley K, Ives N.

Cochrane Database Syst Rev. 2013 Sep 10;(9):CD002817. doi: 10.1002/14651858.CD002817.pub4. Review.


Diffuse intrinsic pontine glioma treated with prolonged temozolomide and radiotherapy--results of a United Kingdom phase II trial (CNS 2007 04).

Bailey S, Howman A, Wheatley K, Wherton D, Boota N, Pizer B, Fisher D, Kearns P, Picton S, Saran F, Gibson M, Glaser A, Connolly DJ, Hargrave D.

Eur J Cancer. 2013 Dec;49(18):3856-62. doi: 10.1016/j.ejca.2013.08.006. Epub 2013 Sep 4.


Optimization of chemotherapy for younger patients with acute myeloid leukemia: results of the medical research council AML15 trial.

Burnett AK, Russell NH, Hills RK, Hunter AE, Kjeldsen L, Yin J, Gibson BE, Wheatley K, Milligan D.

J Clin Oncol. 2013 Sep 20;31(27):3360-8. doi: 10.1200/JCO.2012.47.4874. Epub 2013 Aug 12.


Obesity, independent of p53 gene dosage, promotes mammary tumor progression and upregulates the p53 regulator microRNA-504.

Ford NA, Dunlap SM, Wheatley KE, Hursting SD.

PLoS One. 2013 Jun 28;8(6):e68089. doi: 10.1371/journal.pone.0068089. Print 2013.


Clofarabine doubles the response rate in older patients with acute myeloid leukemia but does not improve survival.

Burnett AK, Russell NH, Hunter AE, Milligan D, Knapper S, Wheatley K, Yin J, McMullin MF, Ali S, Bowen D, Hills RK; UK National Cancer Research Institute AML Working Group.

Blood. 2013 Aug 22;122(8):1384-94. doi: 10.1182/blood-2013-04-496596. Epub 2013 Jul 9.


Home-based reach-to-grasp training for people after stroke: study protocol for a feasibility randomized controlled trial.

Turton AJ, Cunningham P, Heron E, van Wijck F, Sackley C, Rogers C, Wheatley K, Jowett S, Wolf SL, van Vliet P.

Trials. 2013 Apr 25;14:109. doi: 10.1186/1745-6215-14-109.


Plasma exchange and glucocorticoid dosing in the treatment of anti-neutrophil cytoplasm antibody associated vasculitis (PEXIVAS): protocol for a randomized controlled trial.

Walsh M, Merkel PA, Peh CA, Szpirt W, Guillevin L, Pusey CD, De Zoysa J, Ives N, Clark WF, Quillen K, Winters JL, Wheatley K, Jayne D; PEXIVAS Investigators.

Trials. 2013 Mar 14;14:73. doi: 10.1186/1745-6215-14-73.


Intensity-modulated arc therapy to improve radiation dose delivery in the treatment of abdominal neuroblastoma.

Gains JE, Stacey C, Rosenberg I, Mandeville HC, Chang YC, D'Souza D, Moroz V, Wheatley K, Gaze MN.

Future Oncol. 2013 Mar;9(3):439-49. doi: 10.2217/fon.12.199.


Curability of patients with acute myeloid leukemia who did not undergo transplantation in first remission.

Burnett AK, Goldstone A, Hills RK, Milligan D, Prentice A, Yin J, Wheatley K, Hunter A, Russell N.

J Clin Oncol. 2013 Apr 1;31(10):1293-301. doi: 10.1200/JCO.2011.40.5977. Epub 2013 Feb 25.


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