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Peripheral blood smear findings in a kidney transplant recipient with disseminated histoplasmosis and elevated Aspergillus galactomannan.

McCurdy L, Wheat LJ, Block J, Gajurel K.

Transpl Infect Dis. 2019 Jun 6:e13126. doi: 10.1111/tid.13126. [Epub ahead of print]


Rabbit Antithymocyte Globulin Causes Blastomyces and Histoplasma Antigenemia.

Kaur A, Eberlein M, Klesney-Tait J, Durkin MM, Wheat LJ, Gajurel K.

Open Forum Infect Dis. 2019 Mar 28;6(5):ofz165. doi: 10.1093/ofid/ofz165. eCollection 2019 May.


Novel canine anti-Coccidioides immunoglobulin G enzyme immunoassay aids in diagnosis of coccidioidomycosis in dogs.

Holbrook ED, Greene RT, Rubin SI, Renschler JS, Book BP, Hanzlicek AS, Durkin MM, Smedema ML, Wheat LJ.

Med Mycol. 2019 Jan 12. doi: 10.1093/mmy/myy157. [Epub ahead of print]


Cryptococcal meningitis is a cause for cross-reactivity in cerebrospinal fluid assays for anti-Histoplasma, anti-Coccidioides and anti-Blastomyces antibodies.

Bahr NC, Panackal AA, Durkin MM, Smedema ML, Keown W, Davis TE, Raymond-Guillen L, Park YD, Marr KA, Fries BC, Williamson PR, Boulware DR, Wheat LJ.

Mycoses. 2019 Mar;62(3):268-273. doi: 10.1111/myc.12882. Epub 2019 Jan 1.


NMR metabolomics of cerebrospinal fluid differentiates inflammatory diseases of the central nervous system.

French CD, Willoughby RE, Pan A, Wong SJ, Foley JF, Wheat LJ, Fernandez J, Encarnacion R, Ondrush JM, Fatteh N, Paez A, David D, Javaid W, Amzuta IG, Neilan AM, Robbins GK, Brunner AM, Hu WT, Mishchuk DO, Slupsky CM.

PLoS Negl Trop Dis. 2018 Dec 17;12(12):e0007045. doi: 10.1371/journal.pntd.0007045. eCollection 2018 Dec.


Accuracy of a Novel Histoplasmosis Enzyme Immunoassay to Evaluate Suspicious Lung Nodules.

Deppen SA, Massion PP, Blume J, Walker RC, Antic S, Chen H, Durkin MM, Wheat LJ, Grogan EL.

Cancer Epidemiol Biomarkers Prev. 2019 Feb;28(2):321-326. doi: 10.1158/1055-9965.EPI-18-0169. Epub 2018 Oct 19.


Detection of (1,3)-β-d-Glucan in Cerebrospinal Fluid in Histoplasma Meningitis.

Myint T, Chow FC, Bloch KC, Raymond-Guillen L, Davis TE, Wright PW, Woc-Colburn L, Khairy RN, Street AC, Yamamoto T, Albers A, Wheat LJ, Hage CA.

J Clin Microbiol. 2018 Sep 25;56(10). pii: e00663-18. doi: 10.1128/JCM.00663-18. Print 2018 Oct.


GM-CSF therapy in human caspase recruitment domain-containing protein 9 deficiency.

Drummond RA, Zahra FT, Natarajan M, Swamydas M, Hsu AP, Wheat LJ, Gavino C, Vinh DC, Holland SM, Mikelis CM, Lionakis MS.

J Allergy Clin Immunol. 2018 Oct;142(4):1334-1338.e5. doi: 10.1016/j.jaci.2018.05.025. Epub 2018 Jun 8. No abstract available.


Comparison of Compounded, Generic, and Innovator-Formulated Itraconazole in Dogs and Cats.

Renschler J, Albers A, Sinclair-Mackling H, Wheat LJ.

J Am Anim Hosp Assoc. 2018 Jul/Aug;54(4):195-200. doi: 10.5326/JAAHA-MS-6591. Epub 2018 May 14.


Erratum: In vitro activity of isavuconazole against fluconazole-resistant isolates of Histoplasma capsulatum.

Spec A, Connolly P, Montejano R, Wheat LJ.

Med Mycol. 2018 Oct 1;56(7):e1. doi: 10.1093/mmy/myy017. No abstract available.


In vitro activity of isavuconazole against fluconazole-resistant isolates of Histoplasma capsulatum.

Spec A, Connolly P, Montejano R, Wheat LJ.

Med Mycol. 2018 Oct 1;56(7):834-837. doi: 10.1093/mmy/myx130.


Clinical and epidemiological characterization of histoplasmosis cases in a nonendemic area, Connecticut, United States.

Azar MM, Zhang X, Assi R, Hage C, Wheat LJ, Malinis MF.

Med Mycol. 2018 Oct 1;56(7):896-899. doi: 10.1093/mmy/myx120.


Reduced susceptibility to fluconazole in a cat with histoplasmosis.

Renschler JS, Norsworthy GD, Rakian RA, Rakian AI, Wheat LJ, Hanzlicek AS.

JFMS Open Rep. 2017 Nov 28;3(2):2055116917743364. doi: 10.1177/2055116917743364. eCollection 2017 Jul-Dec.


Improvement in Diagnosis of Histoplasma Meningitis by Combined Testing for Histoplasma Antigen and Immunoglobulin G and Immunoglobulin M Anti-Histoplasma Antibody in Cerebrospinal Fluid.

Bloch KC, Myint T, Raymond-Guillen L, Hage CA, Davis TE, Wright PW, Chow FC, Woc-Colburn L, Khairy RN, Street AC, Yamamoto T, Albers A, Wheat LJ.

Clin Infect Dis. 2018 Jan 6;66(1):89-94. doi: 10.1093/cid/cix706.


Seroprevalence of Histoplasmosis in Somali, Burmese, and Hmong Refugees Residing in Thailand and Kenya.

Bahr NC, Lee D, Stauffer WM, Durkin M, Cetron MS, Wheat LJ, Boulware DR.

J Immigr Minor Health. 2018 Apr;20(2):334-338. doi: 10.1007/s10903-017-0595-3.


Peritoneal and genital coccidioidomycosis in an otherwise healthy Danish female: a case report.

Bæk O, Astvad K, Serizawa R, Wheat LJ, Brenøe PT, Hansen AE.

BMC Infect Dis. 2017 Jan 31;17(1):105. doi: 10.1186/s12879-017-2212-4.


Enhanced Antibody Detection and Diagnosis of Coccidioidomycosis with the MiraVista IgG and IgM Detection Enzyme Immunoassay.

Malo J, Holbrook E, Zangeneh T, Strawter C, Oren E, Robey I, Erickson H, Chahal R, Durkin M, Thompson C, Hoover SE, Ampel NM, Wheat LJ, Knox KS.

J Clin Microbiol. 2017 Mar;55(3):893-901. doi: 10.1128/JCM.01880-16. Epub 2017 Jan 4.


Antigen Concentrations as an Indicator of Clinical Remission and Disease Relapse in Cats with Histoplasmosis.

Hanzlicek AS, Meinkoth JH, Renschler JS, Goad C, Wheat LJ.

J Vet Intern Med. 2016 Jul;30(4):1065-73. doi: 10.1111/jvim.13962. Epub 2016 May 9.



Wheat LJ, Azar MM, Bahr NC, Spec A, Relich RF, Hage C.

Infect Dis Clin North Am. 2016 Mar;30(1):207-27. doi: 10.1016/j.idc.2015.10.009. Review.


Improved Diagnosis of Acute Pulmonary Histoplasmosis by Combining Antigen and Antibody Detection.

Richer SM, Smedema ML, Durkin MM, Herman KM, Hage CA, Fuller D, Wheat LJ.

Clin Infect Dis. 2016 Apr 1;62(7):896-902. doi: 10.1093/cid/ciw007. Epub 2016 Jan 20.


Improved Detection of Invasive Pulmonary Aspergillosis Arising during Leukemia Treatment Using a Panel of Host Response Proteins and Fungal Antigens.

Brasier AR, Zhao Y, Spratt HM, Wiktorowicz JE, Ju H, Wheat LJ, Baden L, Stafford S, Wu Z, Issa N, Caliendo AM, Denning DW, Soman K, Clancy CJ, Nguyen MH, Sugrue MW, Alexander BD, Wingard JR.

PLoS One. 2015 Nov 18;10(11):e0143165. doi: 10.1371/journal.pone.0143165. eCollection 2015.


Treatment of Disseminated Aspergillosis with Posaconazole in 10 Dogs.

Corrigan VK, Legendre AM, Wheat LJ, Mullis R, Johnson B, Bemis DA, Cepero L.

J Vet Intern Med. 2016 Jan-Feb;30(1):167-73. doi: 10.1111/jvim.13795. Epub 2015 Nov 14.


Seroprevalence of histoplasmosis in Kampala, Uganda.

Bahr NC, Sarosi GA, Meya DB, Bohjanen PR, Richer SM, Swartzentruber S, Halupnick R, Jarrett D, Wheat LJ, Boulware DR.

Med Mycol. 2016 Mar;54(3):295-300. doi: 10.1093/mmy/myv081. Epub 2015 Nov 2.


Evaluation of an enzyme immunoassay for antibodies to a recombinant Blastomyces adhesin-1 repeat antigen as an aid in the diagnosis of blastomycosis in dogs.

Mourning AC, Patterson EE, Kirsch EJ, Renschler JS, Wolf LA, Paris JK, Durkin MM, Wheat LJ.

J Am Vet Med Assoc. 2015 Nov 15;247(10):1133-8. doi: 10.2460/javma.247.10.1133.


Histoplasmosis: Up-to-Date Evidence-Based Approach to Diagnosis and Management.

Hage CA, Azar MM, Bahr N, Loyd J, Wheat LJ.

Semin Respir Crit Care Med. 2015 Oct;36(5):729-45. doi: 10.1055/s-0035-1562899. Epub 2015 Sep 23. Review.


Cerebrospinal fluid Coccidioides antigen testing in the diagnosis and management of central nervous system coccidioidomycosis.

Bamberger DM, Pepito BS, Proia LA, Ostrosky-Zeichner L, Ashraf M, Marty F, Scully E, Wheat LJ.

Mycoses. 2015 Oct;58(10):598-602. doi: 10.1111/myc.12366. Epub 2015 Sep 3.


Histoplasmosis infections worldwide: thinking outside of the Ohio River valley.

Bahr NC, Antinori S, Wheat LJ, Sarosi GA.

Curr Trop Med Rep. 2015 Jun 1;2(2):70-80.


Role of Coccidioides Antigen Testing in the Cerebrospinal Fluid for the Diagnosis of Coccidioidal Meningitis.

Kassis C, Zaidi S, Kuberski T, Moran A, Gonzalez O, Hussain S, Hartmann-Manrique C, Al-Jashaami L, Chebbo A, Myers RA, Wheat LJ.

Clin Infect Dis. 2015 Nov 15;61(10):1521-6. doi: 10.1093/cid/civ585. Epub 2015 Jul 24.


Performance Characteristics of Galactomannan and β-d-Glucan in High-Risk Liver Transplant Recipients.

Singh N, Winston DJ, Limaye AP, Pelletier S, Safdar N, Morris MI, Meneses K, Busuttil RW, Wagener MM, Wheat LJ.

Transplantation. 2015 Dec;99(12):2543-50. doi: 10.1097/TP.0000000000000763.


Blastomycosis in Indiana: Clinical and Epidemiologic Patterns of Disease Gleaned from a Multicenter Retrospective Study.

Azar MM, Assi R, Relich RF, Schmitt BH, Norris S, Wheat LJ, Hage CA.

Chest. 2015 Nov;148(5):1276-1284. doi: 10.1378/chest.15-0289.


Coughing spells in a Michiganian girl after a trip to Southwest US.

Salama H, Wheat LJ, Sobel JD, Srivastava R, Richer SM, Rongkavilit C.

Pediatr Infect Dis J. 2015 May;34(5):546, 553-4. doi: 10.1097/INF.0000000000000657. No abstract available.


Histoplasmosis complicating tumor necrosis factor-α blocker therapy: a retrospective analysis of 98 cases.

Vergidis P, Avery RK, Wheat LJ, Dotson JL, Assi MA, Antoun SA, Hamoud KA, Burdette SD, Freifeld AG, McKinsey DS, Money ME, Myint T, Andes DR, Hoey CA, Kaul DA, Dickter JK, Liebers DE, Miller RA, Muth WE, Prakash V, Steiner FT, Walker RC, Hage CA.

Clin Infect Dis. 2015 Aug 1;61(3):409-17. doi: 10.1093/cid/civ299. Epub 2015 Apr 13.


Positive (1-3) B-d-glucan and cross reactivity of fungal assays in coccidioidomycosis.

Zangeneh TT, Malo J, Luraschi-Monjagatta C, Hage CA, Wheat LJ, Strawter C, Klotz SA, Knox KS.

Med Mycol. 2015 Feb 1;53(2):171-3. doi: 10.1093/mmy/myu077. Epub 2014 Dec 24.


(1,3)-β-d-glucan in cerebrospinal fluid for diagnosis of fungal meningitis associated with contaminated methylprednisolone injections.

Malani AN, Singal B, Wheat LJ, Al Sous O, Summons TA, Durkin MM, Pettit AC.

J Clin Microbiol. 2015 Mar;53(3):799-803. doi: 10.1128/JCM.02952-14. Epub 2014 Dec 24.


Low-positive histoplasma antigen results in the MVista assay should not be assumed to be false positive.

Hage CA, Wheat LJ.

J Clin Microbiol. 2014 Dec;52(12):4445. doi: 10.1128/JCM.02514-14. No abstract available.


Reply to "Insufficient demonstration of long-term stability of Aspergillus galactomannan".

Wheat LJ, Nguyen MH, Alexander BD, Denning D, Caliendo AM, Lyon GM, Baden LR, Marty FM, Clancy C, Kirsch E, Noth P, Witt J, Sugrue M, Wingard JR.

J Clin Microbiol. 2014 Nov;52(11):4119. doi: 10.1128/JCM.02433-14. No abstract available.


Histoplasma capsulatum endocarditis: multicenter case series with review of current diagnostic techniques and treatment.

Riddell J 4th, Kauffman CA, Smith JA, Assi M, Blue S, Buitrago MI, Deresinski S, Wright PW, Drevets DA, Norris SA, Vikram HR, Carson PJ, Vergidis P, Carpenter J, Seidenfeld SM, Wheat LJ.

Medicine (Baltimore). 2014 Jul;93(5):186-93. doi: 10.1097/MD.0000000000000034.


Glycosylation and immunoreactivity of the Histoplasma capsulatum Cfp4 yeast-phase exoantigen.

Holbrook ED, Kemski MM, Richer SM, Wheat LJ, Rappleye CA.

Infect Immun. 2014 Oct;82(10):4414-25. doi: 10.1128/IAI.01893-14. Epub 2014 Aug 11.


Cryptococcal meningitis post autologous stem cell transplantation.

Chaaban S, Wheat LJ, Assi M.

Transpl Infect Dis. 2014 Jun;16(3):473-6. doi: 10.1111/tid.12216. Epub 2014 Apr 21.


Long-term stability at -20 °C of Aspergillus galactomannan in serum and bronchoalveolar lavage specimens.

Wheat LJ, Nguyen MH, Alexander BD, Denning D, Caliendo AM, Lyon GM, Baden LR, Marty FM, Clancy C, Kirsch E, Noth P, Witt J, Sugrue M, Wingard JR.

J Clin Microbiol. 2014 Jun;52(6):2108-11. doi: 10.1128/JCM.03500-13. Epub 2014 Apr 9.


Reduction in false-positive Aspergillus serum galactomannan enzyme immunoassay results associated with use of piperacillin-tazobactam in the United States.

Vergidis P, Razonable RR, Wheat LJ, Estes L, Caliendo AM, Baden LR, Wingard JR, Baddley J, Assi M, Norris S, Chandrasekar P, Shields R, Nguyen H, Freifeld A, Kohler R, Kleiman M, Walsh TJ, Hage CA.

J Clin Microbiol. 2014 Jun;52(6):2199-201. doi: 10.1128/JCM.00285-14. Epub 2014 Apr 9.


Serum and urine Blastomyces antigen concentrations as markers of clinical remission in dogs treated for systemic blastomycosis.

Foy DS, Trepanier LA, Kirsch EJ, Wheat LJ.

J Vet Intern Med. 2014 Mar-Apr;28(2):305-10. doi: 10.1111/jvim.12306. Epub 2014 Feb 3.


Histoplasmosis in patients with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS): multicenter study of outcomes and factors associated with relapse.

Myint T, Anderson AM, Sanchez A, Farabi A, Hage C, Baddley JW, Jhaveri M, Greenberg RN, Bamberger DM, Rodgers M, Crawford TN, Wheat LJ.

Medicine (Baltimore). 2014 Jan;93(1):11-8. doi: 10.1097/MD.0000000000000016.


Development of a highly sensitive and specific blastomycosis antibody enzyme immunoassay using Blastomyces dermatitidis surface protein BAD-1.

Richer SM, Smedema ML, Durkin MM, Brandhorst TT, Hage CA, Connolly PA, Leland DS, Davis TE, Klein BS, Wheat LJ.

Clin Vaccine Immunol. 2014 Feb;21(2):143-6. doi: 10.1128/CVI.00597-13. Epub 2013 Nov 27.


Histoplasmosis after solid organ transplant.

Assi M, Martin S, Wheat LJ, Hage C, Freifeld A, Avery R, Baddley JW, Vergidis P, Miller R, Andes D, Young JA, Hammoud K, Huprikar S, McKinsey D, Myint T, Garcia-Diaz J, Esguerra E, Kwak EJ, Morris M, Mullane KM, Prakash V, Burdette SD, Sandid M, Dickter J, Ostrander D, Antoun SA, Kaul DR.

Clin Infect Dis. 2013 Dec;57(11):1542-9. doi: 10.1093/cid/cit593. Epub 2013 Sep 17.


Immunological characterization of bronchoalveolar lavage fluid in patients with acute pulmonary coccidioidomycosis.

Nesbit LA, Knox KS, Nguyen CT, Roesch J, Wheat LJ, Johnson SM, Pappagianis D, Chavez S, Ampel NM.

J Infect Dis. 2013 Sep 1;208(5):857-63. doi: 10.1093/infdis/jit246. Epub 2013 Jun 3.


Development and evaluation of a calibrator material for nucleic acid-based assays for diagnosing aspergillosis.

Lyon GM, Abdul-Ali D, Loeffler J, White PL, Wickes B, Herrera ML, Alexander BD, Baden LR, Clancy C, Denning D, Nguyen MH, Sugrue M, Wheat LJ, Wingard JR, Donnelly JP, Barnes R, Patterson TF, Caliendo AM; AsTeC, IAAM, EAPCRI Investigators.

J Clin Microbiol. 2013 Jul;51(7):2403-5. doi: 10.1128/JCM.00744-13. Epub 2013 Apr 24.


Histoplasma capsulatum preferentially induces IDO in the lung.

Hage CA, Horan DJ, Durkin M, Connolly P, Desta Z, Skaar TC, Knox KS, Wheat LJ.

Med Mycol. 2013 Apr;51(3):270-9. doi: 10.3109/13693786.2012.710857. Epub 2012 Nov 27.


Histoplasmosis among hospitalized febrile patients in northern Tanzania.

Lofgren SM, Kirsch EJ, Maro VP, Morrissey AB, Msuya LJ, Kinabo GD, Saganda W, Diefenthal HC, Ramadhani HO, Wheat LJ, Crump JA.

Trans R Soc Trop Med Hyg. 2012 Aug;106(8):504-7. doi: 10.1016/j.trstmh.2012.05.009. Epub 2012 Jun 26.


Donor-derived fungal infections in organ transplant recipients: guidelines of the American Society of Transplantation, infectious diseases community of practice.

Singh N, Huprikar S, Burdette SD, Morris MI, Blair JE, Wheat LJ; American Society of Transplantation, Infectious Diseases Community of Practice, Donor-Derived Fungal Infection Working Group.

Am J Transplant. 2012 Sep;12(9):2414-28. doi: 10.1111/j.1600-6143.2012.04100.x. Epub 2012 Jun 13.

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