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Items: 28


Targeted Doxorubicin-Loaded Bacterially Derived Nano-Cells for the Treatment of Neuroblastoma.

Sagnella SM, Trieu J, Brahmbhatt H, MacDiarmid JA, MacMillan A, Whan RM, Fife CM, McCarroll JA, Gifford AJ, Ziegler DS, Kavallaris M.

Mol Cancer Ther. 2018 May;17(5):1012-1023. doi: 10.1158/1535-7163.MCT-17-0738. Epub 2018 Feb 28.


Velocity landscape correlation resolves multiple flowing protein populations from fluorescence image time series.

Pandžić E, Abu-Arish A, Whan RM, Hanrahan JW, Wiseman PW.

Methods. 2018 May 1;140-141:126-139. doi: 10.1016/j.ymeth.2018.02.011. Epub 2018 Feb 16.


Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis.

Vennin C, Chin VT, Warren SC, Lucas MC, Herrmann D, Magenau A, Melenec P, Walters SN, Del Monte-Nieto G, Conway JR, Nobis M, Allam AH, McCloy RA, Currey N, Pinese M, Boulghourjian A, Zaratzian A, Adam AA, Heu C, Nagrial AM, Chou A, Steinmann A, Drury A, Froio D, Giry-Laterriere M, Harris NL, Phan T, Jain R, Weninger W, McGhee EJ, Whan R, Johns AL, Samra JS, Chantrill L, Gill AJ, Kohonen-Corish M, Harvey RP, Biankin AV; Australian Pancreatic Cancer Genome Initiative (APGI), Evans TR, Anderson KI, Grey ST, Ormandy CJ, Gallego-Ortega D, Wang Y, Samuel MS, Sansom OJ, Burgess A, Cox TR, Morton JP, Pajic M, Timpson P.

Sci Transl Med. 2017 Apr 5;9(384). pii: eaai8504. doi: 10.1126/scitranslmed.aai8504.


Live Tissue Imaging to Elucidate Mechanical Modulation of Stem Cell Niche Quiescence.

Yu NY, O'Brien CA, Slapetova I, Whan RM, Knothe Tate ML.

Stem Cells Transl Med. 2017 Jan;6(1):285-292. doi: 10.5966/sctm.2015-0306. Epub 2016 Jul 28.


The ATP binding cassette transporter, ABCG1, localizes to cortical actin filaments.

Pandzic E, Gelissen IC, Whan R, Barter PJ, Sviridov D, Gaus K, Rye KA, Cochran BJ.

Sci Rep. 2017 Feb 6;7:42025. doi: 10.1038/srep42025.


Scale-up of nature's tissue weaving algorithms to engineer advanced functional materials.

Ng JL, Knothe LE, Whan RM, Knothe U, Tate ML.

Sci Rep. 2017 Jan 11;7:40396. doi: 10.1038/srep40396.


The Polyphenol Altenusin Inhibits in Vitro Fibrillization of Tau and Reduces Induced Tau Pathology in Primary Neurons.

Chua SW, Cornejo A, van Eersel J, Stevens CH, Vaca I, Cueto M, Kassiou M, Gladbach A, Macmillan A, Lewis L, Whan R, Ittner LM.

ACS Chem Neurosci. 2017 Apr 19;8(4):743-751. doi: 10.1021/acschemneuro.6b00433. Epub 2017 Jan 12.


Effect of surface chemistry on tropomyosin binding to actin filaments on surfaces.

Nicovich PR, Janco M, Sobey T, Gajwani M, Obeidy P, Whan R, Gaus K, Gunning PW, Coster AC, Böcking T.

Cytoskeleton (Hoboken). 2016 Dec;73(12):729-738. doi: 10.1002/cm.21342. Epub 2016 Nov 23.


Translating Periosteum's Regenerative Power: Insights From Quantitative Analysis of Tissue Genesis With a Periosteum Substitute Implant.

Moore SR, Heu C, Yu NY, Whan RM, Knothe UR, Milz S, Knothe Tate ML.

Stem Cells Transl Med. 2016 Dec;5(12):1739-1749. Epub 2016 Jul 27.


STED imaging of tau filaments in Alzheimer's disease cortical grey matter.

Benda A, Aitken H, Davies DS, Whan R, Goldsbury C.

J Struct Biol. 2016 Sep;195(3):345-352. doi: 10.1016/j.jsb.2016.07.003. Epub 2016 Jul 9.


PDGF-AB and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells.

Chandrakanthan V, Yeola A, Kwan JC, Oliver RA, Qiao Q, Kang YC, Zarzour P, Beck D, Boelen L, Unnikrishnan A, Villanueva JE, Nunez AC, Knezevic K, Palu C, Nasrallah R, Carnell M, Macmillan A, Whan R, Yu Y, Hardy P, Grey ST, Gladbach A, Delerue F, Ittner L, Mobbs R, Walkley CR, Purton LE, Ward RL, Wong JW, Hesson LB, Walsh W, Pimanda JE.

Proc Natl Acad Sci U S A. 2016 Apr 19;113(16):E2306-15. doi: 10.1073/pnas.1518244113. Epub 2016 Apr 4.


Heterologously-expressed and Liposome-reconstituted Human Transient Receptor Potential Melastatin 4 Channel (TRPM4) is a Functional Tetramer.

Constantine M, Liew CK, Lo V, Macmillan A, Cranfield CG, Sunde M, Whan R, Graham RM, Martinac B.

Sci Rep. 2016 Jan 20;6:19352. doi: 10.1038/srep19352.


The nuclear localization pattern and interaction partners of GTF2IRD1 demonstrate a role in chromatin regulation.

Carmona-Mora P, Widagdo J, Tomasetig F, Canales CP, Cha Y, Lee W, Alshawaf A, Dottori M, Whan RM, Hardeman EC, Palmer SJ.

Hum Genet. 2015 Oct;134(10):1099-115. doi: 10.1007/s00439-015-1591-0. Epub 2015 Aug 15.


The endocytic pathway and therapeutic efficiency of doxorubicin conjugated cholesterol-derived polymers.

Sevimli S, Sagnella S, Macmillan A, Whan R, Kavallaris M, Bulmus V, Davis TP.

Biomater Sci. 2015 Feb;3(2):323-35. doi: 10.1039/c4bm00224e. Epub 2014 Sep 25.


Distribution of raphespinal fibers in the mouse spinal cord.

Liang H, Wang S, Francis R, Whan R, Watson C, Paxinos G.

Mol Pain. 2015 Jul 16;11:42. doi: 10.1186/s12990-015-0046-x.


Cell elasticity is regulated by the tropomyosin isoform composition of the actin cytoskeleton.

Jalilian I, Heu C, Cheng H, Freittag H, Desouza M, Stehn JR, Bryce NS, Whan RM, Hardeman EC, Fath T, Schevzov G, Gunning PW.

PLoS One. 2015 May 15;10(5):e0126214. doi: 10.1371/journal.pone.0126214. eCollection 2015.


Measuring sperm movement within the female reproductive tract using Fourier analysis.

Nicovich PR, Macartney EL, Whan RM, Crean AJ.

Microsc Microanal. 2015 Feb;21(1):256-63. doi: 10.1017/S1431927614014627. Epub 2015 Feb 2.


Fluorescence recovery after photobleaching (FRAP): acquisition, analysis, and applications.

Carnell M, Macmillan A, Whan R.

Methods Mol Biol. 2015;1232:255-71. doi: 10.1007/978-1-4939-1752-5_18.


Nanoparticles based on star polymers as theranostic vectors: endosomal-triggered drug release combined with MRI sensitivity.

Li Y, Duong HT, Laurent S, MacMillan A, Whan RM, Elst LV, Muller RN, Hu J, Lowe A, Boyer C, Davis TP.

Adv Healthc Mater. 2015 Jan 7;4(1):148-56. doi: 10.1002/adhm.201400164. Epub 2014 Jul 1.


Tracing the fate of limbal epithelial progenitor cells in the murine cornea.

Di Girolamo N, Bobba S, Raviraj V, Delic NC, Slapetova I, Nicovich PR, Halliday GM, Wakefield D, Whan R, Lyons JG.

Stem Cells. 2015 Jan;33(1):157-69. doi: 10.1002/stem.1769.


Dextran-based doxorubicin nanocarriers with improved tumor penetration.

Sagnella SM, Duong H, MacMillan A, Boyer C, Whan R, McCarroll JA, Davis TP, Kavallaris M.

Biomacromolecules. 2014 Jan 13;15(1):262-75. doi: 10.1021/bm401526d. Epub 2013 Dec 18.


Using fluorescence lifetime imaging microscopy to monitor theranostic nanoparticle uptake and intracellular doxorubicin release.

Basuki JS, Duong HT, Macmillan A, Erlich RB, Esser L, Akerfeldt MC, Whan RM, Kavallaris M, Boyer C, Davis TP.

ACS Nano. 2013 Nov 26;7(11):10175-89. doi: 10.1021/nn404407g. Epub 2013 Oct 16.


Functionalizing biodegradable dextran scaffolds using living radical polymerization: new versatile nanoparticles for the delivery of therapeutic molecules.

Duong HT, Hughes F, Sagnella S, Kavallaris M, Macmillan A, Whan R, Hook J, Davis TP, Boyer C.

Mol Pharm. 2012 Nov 5;9(11):3046-61. doi: 10.1021/mp300144y. Epub 2012 Oct 18.


SPontaneous Oscillatory Contraction (SPOC): auto-oscillations observed in striated muscle at partial activation.

Wolfe JE, Ishiwata S, Braet F, Whan R, Su Y, Lal S, Dos Remedios CG.

Biophys Rev. 2011 Jun;3(2):53-62. doi: 10.1007/s12551-011-0046-7. Epub 2011 May 4. Review.


Multi-dimensional correlative imaging of subcellular events: combining the strengths of light and electron microscopy.

Su Y, Nykanen M, Jahn KA, Whan R, Cantrill L, Soon LL, Ratinac KR, Braet F.

Biophys Rev. 2010 Aug;2(3):121-135. doi: 10.1007/s12551-010-0035-2. Epub 2010 Jul 28. Review.


Accumulation of an anthraquinone and its platinum complexes in cancer cell spheroids: the effect of charge on drug distribution in solid tumour models.

Bryce NS, Zhang JZ, Whan RM, Yamamoto N, Hambley TW.

Chem Commun (Camb). 2009 May 21;(19):2673-5. doi: 10.1039/b902415h. Epub 2009 Mar 23.


Development of the five primary podia from the coeloms of a sea star larva: homology with the echinoid echinoderms and other deuterostomes.

Morris VB, Selvakumaraswamy P, Whan R, Byrne M.

Proc Biol Sci. 2009 Apr 7;276(1660):1277-84. doi: 10.1098/rspb.2008.1659. Epub 2009 Jan 6.

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